2,2-Dichloro-1,1,1,3,3-pentafluoropropane

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  • Identifiers

    CAS number
    128903-21-9

    Molecular formula
    C3HCl2F5

    SMILES
    C(C(C(F)(F)F)(Cl)Cl)(F)F

  • Odor profile

    Fragrance
    Odorless 55.55%
    Fishy 26.9%
    Woody 24.78%
    Cooling 22.27%
    Sweet 21.87%
    Balsamic 17.98%
    Animal 17.04%
    Savory 16.21%
    Mint 16.12%
    Dry 15.52%

     

    Flavor
    Odorless 32.19%
    Bland 21.52%
    Sulfurous 21.24%
    Mild 18.13%
    Sweet-like 17.8%
    Bloody 17.72%
    Glue 17.56%
    Bitter 17.43%
    Bouillon 17.37%
    Skunky 17.07%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    5.48 (weak acid)

    Molecular weight
    202.93 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    55°C

    Flash point

    • 3.04 ˚C est.

  • Synonyms

    • 2,2-DICHLORO-1,1,1,3,3-PENTAFLUOROPROPANE
    • 128903-21-9
    • HCFC-225aa
    • HCFC 225aa
    • 2,2-DICHLORO-1,1,1,3,3-PENTAFLUORO-PROPANE
    • 801K277HE4
    • DTXSID6042024
    • UNII-801K277HE4
    • R-225AA
    • Propane, 2,2-dichloro-1,1,1,3,3-pentafluoro-
    • 1,1,1,3,3-PENTAFLUORO-2,2-DICHLOROPROPANE
    • pentafluorodichloropropane
    • SCHEMBL224372
    • DTXCID4022024
    • FD86332
    • NS00122485
    • Q27894274

  • Applications

    This highly halogenated compound is commonly evaluated as a specialty solvent and processing aid in coatings, inks, and cleaning formulations; serves as an intermediate in the synthesis of fluorinated polymers and related materials; can function as a blowing agent or feedstock for polymer foams; and may appear as a component in refrigerant or heat-transfer fluid formulations, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 459.39
    methanol 926.47
    isopropanol 372.19
    water 195.28
    ethyl acetate 157.59
    n-propanol 317.84
    acetone 517.23
    n-butanol 254.06
    acetonitrile 434.88
    DMF 1499.16
    toluene 68.23
    isobutanol 244.13
    1,4-dioxane 282.34
    methyl acetate 214.19
    THF 626.31
    2-butanone 345.71
    n-pentanol 206.44
    sec-butanol 284.23
    n-hexane 45.51
    ethylene glycol 247.99
    NMP 981.32
    cyclohexane 40.26
    DMSO 1476.32
    n-butyl acetate 94.16
    n-octanol 87.34
    chloroform 132.63
    n-propyl acetate 150.54
    acetic acid 230.29
    dichloromethane 170.13
    cyclohexanone 240.56
    propylene glycol 212.58
    isopropyl acetate 130.6
    DMAc 1250.44
    2-ethoxyethanol 437.86
    isopentanol 210.1
    n-heptane 43.93
    ethyl formate 168.68
    1,2-dichloroethane 151.7
    n-hexanol 132.43
    2-methoxyethanol 640.47
    isobutyl acetate 83.16
    tetrachloromethane 33.77
    n-pentyl acetate 67.8
    transcutol 358.34
    n-heptanol 81.5
    ethylbenzene 55.1
    MIBK 193.78
    2-propoxyethanol 312.67
    tert-butanol 384.49
    MTBE 241.36
    2-butoxyethanol 163.83
    propionic acid 148.95
    o-xylene 83.89
    formic acid 290.19
    diethyl ether 294.42
    m-xylene 74.55
    p-xylene 62.89
    chlorobenzene 30.55
    dimethyl carbonate 184.36
    n-octane 18.06
    formamide 561.28
    cyclopentanone 357.09
    2-pentanone 292.18
    anisole 139.78
    cyclopentyl methyl ether 288.1
    gamma-butyrolactone 322.0
    1-methoxy-2-propanol 546.09
    pyridine 185.81
    3-pentanone 240.55
    furfural 255.67
    n-dodecane 12.21
    diethylene glycol 282.33
    diisopropyl ether 101.12
    tert-amyl alcohol 291.63
    acetylacetone 235.59
    n-hexadecane 12.55
    acetophenone 153.16
    methyl propionate 222.39
    isopentyl acetate 71.79
    trichloroethylene 138.59
    n-nonanol 80.96
    cyclohexanol 165.86
    benzyl alcohol 127.8
    2-ethylhexanol 78.78
    isooctanol 63.73
    dipropyl ether 163.35
    1,2-dichlorobenzene 30.57
    ethyl lactate 153.66
    propylene carbonate 147.56
    n-methylformamide 639.67
    2-pentanol 212.45
    n-pentane 72.51
    1-propoxy-2-propanol 230.55
    1-methoxy-2-propyl acetate 145.46
    2-(2-methoxypropoxy) propanol 174.82
    mesitylene 58.23
    ε-caprolactone 185.07
    p-cymene 48.43
    epichlorohydrin 302.4
    1,1,1-trichloroethane 77.68
    2-aminoethanol 325.39
    morpholine-4-carbaldehyde 649.72
    sulfolane 465.49
    2,2,4-trimethylpentane 27.26
    2-methyltetrahydrofuran 325.5
    n-hexyl acetate 83.27
    isooctane 21.54
    2-(2-butoxyethoxy)ethanol 188.78
    sec-butyl acetate 94.62
    tert-butyl acetate 144.16
    decalin 20.57
    glycerin 266.2
    diglyme 335.92
    acrylic acid 145.16
    isopropyl myristate 49.28
    n-butyric acid 141.62
    acetyl acetate 78.42
    di(2-ethylhexyl) phthalate 45.06
    ethyl propionate 152.4
    nitromethane 537.45
    1,2-diethoxyethane 144.96
    benzonitrile 86.75
    trioctyl phosphate 42.34
    1-bromopropane 136.52
    gamma-valerolactone 409.0
    n-decanol 63.33
    triethyl phosphate 69.29
    4-methyl-2-pentanol 132.02
    propionitrile 263.25
    vinylene carbonate 115.62
    1,1,2-trichlorotrifluoroethane 232.74
    DMS 82.24
    cumene 48.08
    2-octanol 61.1
    2-hexanone 217.43
    octyl acetate 59.51
    limonene 70.32
    1,2-dimethoxyethane 615.67
    ethyl orthosilicate 67.36
    tributyl phosphate 47.07
    diacetone alcohol 252.87
    N,N-dimethylaniline 194.26
    acrylonitrile 273.79
    aniline 106.39
    1,3-propanediol 270.18
    bromobenzene 24.79
    dibromomethane 134.5
    1,1,2,2-tetrachloroethane 140.71
    2-methyl-cyclohexyl acetate 82.66
    tetrabutyl urea 103.54
    diisobutyl methanol 63.71
    2-phenylethanol 90.65
    styrene 53.45
    dioctyl adipate 69.1
    dimethyl sulfate 267.39
    ethyl butyrate 118.41
    methyl lactate 224.92
    butyl lactate 84.0
    diethyl carbonate 75.2
    propanediol butyl ether 151.15
    triethyl orthoformate 89.38
    p-tert-butyltoluene 48.35
    methyl 4-tert-butylbenzoate 120.69
    morpholine 442.69
    tert-butylamine 274.01
    n-dodecanol 50.69
    dimethoxymethane 782.58
    ethylene carbonate 107.22
    cyrene 243.24
    2-ethoxyethyl acetate 83.11
    2-ethylhexyl acetate 57.47
    1,2,4-trichlorobenzene 39.66
    4-methylpyridine 192.39
    dibutyl ether 85.72
    2,6-dimethyl-4-heptanol 63.71
    DEF 447.59
    dimethyl isosorbide 275.27
    tetrachloroethylene 87.49
    eugenol 123.66
    triacetin 94.48
    span 80 108.47
    1,4-butanediol 172.68
    1,1-dichloroethane 120.24
    2-methyl-1-pentanol 156.55
    methyl formate 402.43
    2-methyl-1-butanol 208.7
    n-decane 19.91
    butyronitrile 219.87
    3,7-dimethyl-1-octanol 77.11
    1-chlorooctane 41.86
    1-chlorotetradecane 21.05
    n-nonane 20.54
    undecane 14.97
    tert-butylcyclohexane 20.98
    cyclooctane 22.56
    cyclopentanol 220.72
    tetrahydropyran 234.67
    tert-amyl methyl ether 227.76
    2,5,8-trioxanonane 271.52
    1-hexene 98.26
    2-isopropoxyethanol 282.37
    2,2,2-trifluoroethanol 168.58
    methyl butyrate 199.35

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction