2-t-Butyl-4-methylphenol

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  • Identifiers

    CAS number
    2409-55-4

    Molecular formula
    C11H16O

    SMILES
    CC1=CC(=C(C=C1)O)C(C)(C)C

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Phenolic 73.63%
    Leathery 62.0%
    Smoky 50.98%
    Medicinal 49.27%
    Spicy 47.1%
    Woody 45.53%
    Animal 38.81%
    Burnt 36.63%
    Dry 35.42%
    Camphoreous 32.71%

     

    Flavor
    Phenolic 63.33%
    Camphor 46.25%
    Medicinal 43.25%
    Woody 35.15%
    Leather 34.49%
    Musty 33.06%
    Smoke 29.17%
    Spice 29.02%
    Smoky 27.84%
    Mild 27.82%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.6

    pKa est.
    9.87 (weak base)

    Molecular weight
    164.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Melting point expt.

    • 55 °C

    Boiling point

    • 237 °C

    Flash point

    • 107.0 ˚C est.
    • 105 °C

    Solubility expt.

    • Insoluble in water, soluble in oxygenated solvents.

  • Synonyms

    • 2-tert-Butyl-4-methylphenol
    • 2409-55-4
    • 2-tert-Butyl-p-cresol
    • 2-(tert-butyl)-4-methylphenol
    • 4-Methyl-2-tert-butylphenol
    • o-tert-Butyl-p-cresol
    • p-Cresol, 2-tert-butyl-
    • 2-t-Butyl-p-cresol
    • 4-Methyl-6-t-butylphenol
    • 2-Terc.butyl-p-kresol
    • 2-T-BUTYL-4-METHYLPHENOL
    • 4-Methyl-2-t-butylphenol
    • Phenol, 2-(1,1-dimethylethyl)-4-methyl-
    • 2-tert-Butyl-4-methyl-1-phenol
    • 1-Hydroxy-2-tert-butyl-4-methylbenzene
    • 2-(1,1-Dimethylethyl)-4-methylphenol
    • Phenol, (1,1-dimethylethyl)-4-methyl-
    • NSC 60301
    • 2-tert-Butyl-4-methyl-phenol
    • CCRIS 4045
    • 2-terc.Butyl-p-kresol [Czech]
    • 4-Methyl-2-(1,1-dimethylethyl)phenol
    • HSDB 5875
    • EINECS 219-314-6
    • Y9VVU7G7J4
    • MFCD00002381
    • BRN 1817645
    • DTXSID2020212
    • NSC-60301
    • DTXCID00212
    • 25567-40-2
    • EC 219-314-6
    • 4-06-00-03397 (Beilstein Handbook Reference)
    • EINECS 247-108-6
    • BUTYL-4-METHYLPHENOL, 2-TERT-
    • 2-T-BUTYL-4-METHYLPHENOL [HSDB]
    • 2-TBMP
    • CAS-2409-55-4
    • UNII-Y9VVU7G7J4
    • 2tButylpcresol
    • otertButylpcresol
    • 2tertButylpcresol
    • t-butyl p-cresol
    • 2terc.Butylpkresol
    • 4Methyl2tbutylphenol
    • 4Methyl6tbutylphenol
    • pCresol, 2tertbutyl
    • 2tertButyl4methylphenol
    • 4Methyl2tertbutylphenol
    • 2tertButyl4methyl1phenol
    • 2-tert-Butyl-4-cresol
    • mono-tert-butyl-p-cresol
    • TimTec1_002162
    • SCHEMBL270433
    • 2-TERC BUTYL-P-KRESOL
    • 2-tertiarybutyl-4-methylphenol
    • CHEMBL281976
    • 1Hydroxy2tertbutyl4methylbenzene
    • phenol, 2-tert-butyl-4-methyl-
    • T-BUTYL P-CRESOL [INCI]
    • 2(1,1Dimethylethyl)4methylphenol
    • 4Methyl2(1,1dimethylethyl)phenol
    • HMS1540C06
    • NSC60301
    • Phenol,1-dimethylethyl)-4-methyl-
    • WLN: QR D1 BX1&1&1
    • Tox21_201938
    • Tox21_303003
    • 2-tert-Butyl-4-methylphenol, 99%
    • Phenol, 2(1,1dimethylethyl)4methyl
    • STK367442
    • AKOS000120238
    • CS-W016085
    • 2-TERC BUTYL-P-KRESOL (CZECH)
    • 2-(1,1-Dimethylethyl)-4-methyl-phenol
    • NCGC00249138-01
    • NCGC00249138-02
    • NCGC00256616-01
    • NCGC00259487-01
    • LS-13987
    • DB-019858
    • B0910
    • NS00004882
    • EN300-20370
    • D84620
    • AB00443915-03
    • BRD-K22403246-001-01-7
    • Q27294416
    • F0001-0824
    • Z104477904

  • Applications

    2-t-Butyl-4-methylphenol (CAS 2409-55-4) is a hindered phenolic antioxidant used mainly as a stabilizer to limit thermo-oxidative degradation in polymers and elastomers; it is also employed as an antioxidant additive in lubricants and fuels to preserve properties and performance during storage and use. In coatings and inks, it serves as a processing stabilizer to improve handling and film integrity, and it can function as a chemical intermediate in the synthesis of specialty antioxidants and related derivatives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 543.68
    methanol 480.5
    isopropanol 750.97
    water 0.96
    ethyl acetate 888.36
    n-propanol 658.02
    acetone 1165.53
    n-butanol 660.4
    acetonitrile 888.95
    DMF 1070.26
    toluene 415.73
    isobutanol 610.71
    1,4-dioxane 1409.8
    methyl acetate 850.04
    THF 3150.39
    2-butanone 1100.7
    n-pentanol 470.87
    sec-butanol 720.27
    n-hexane 443.6
    ethylene glycol 104.82
    NMP 857.19
    cyclohexane 338.85
    DMSO 678.56
    n-butyl acetate 852.15
    n-octanol 559.22
    chloroform 1328.78
    n-propyl acetate 523.6
    acetic acid 271.39
    dichloromethane 958.97
    cyclohexanone 1233.22
    propylene glycol 236.04
    isopropyl acetate 632.74
    DMAc 700.55
    2-ethoxyethanol 426.31
    isopentanol 599.94
    n-heptane 287.02
    ethyl formate 474.21
    1,2-dichloroethane 785.54
    n-hexanol 1190.99
    2-methoxyethanol 637.52
    isobutyl acetate 406.03
    tetrachloromethane 285.37
    n-pentyl acetate 458.82
    transcutol 773.27
    n-heptanol 507.23
    ethylbenzene 367.42
    MIBK 687.86
    2-propoxyethanol 1043.19
    tert-butanol 1090.26
    MTBE 1268.45
    2-butoxyethanol 527.74
    propionic acid 438.47
    o-xylene 300.12
    formic acid 70.85
    diethyl ether 1122.56
    m-xylene 410.86
    p-xylene 424.93
    chlorobenzene 452.8
    dimethyl carbonate 311.06
    n-octane 143.94
    formamide 109.61
    cyclopentanone 1819.45
    2-pentanone 1006.59
    anisole 574.95
    cyclopentyl methyl ether 1384.25
    gamma-butyrolactone 1536.83
    1-methoxy-2-propanol 770.97
    pyridine 659.41
    3-pentanone 724.51
    furfural 703.79
    n-dodecane 109.2
    diethylene glycol 465.84
    diisopropyl ether 487.35
    tert-amyl alcohol 853.59
    acetylacetone 742.53
    n-hexadecane 122.11
    acetophenone 389.33
    methyl propionate 744.94
    isopentyl acetate 773.06
    trichloroethylene 1187.3
    n-nonanol 472.9
    cyclohexanol 698.47
    benzyl alcohol 314.43
    2-ethylhexanol 614.04
    isooctanol 411.22
    dipropyl ether 786.15
    1,2-dichlorobenzene 392.3
    ethyl lactate 258.08
    propylene carbonate 784.4
    n-methylformamide 430.19
    2-pentanol 662.34
    n-pentane 310.34
    1-propoxy-2-propanol 801.33
    1-methoxy-2-propyl acetate 705.14
    2-(2-methoxypropoxy) propanol 367.0
    mesitylene 299.7
    ε-caprolactone 920.32
    p-cymene 257.33
    epichlorohydrin 1419.93
    1,1,1-trichloroethane 997.71
    2-aminoethanol 222.96
    morpholine-4-carbaldehyde 823.49
    sulfolane 1386.38
    2,2,4-trimethylpentane 145.58
    2-methyltetrahydrofuran 1849.68
    n-hexyl acetate 766.12
    isooctane 154.14
    2-(2-butoxyethoxy)ethanol 563.33
    sec-butyl acetate 395.06
    tert-butyl acetate 752.34
    decalin 183.07
    glycerin 217.37
    diglyme 825.65
    acrylic acid 282.69
    isopropyl myristate 332.05
    n-butyric acid 620.53
    acetyl acetate 401.8
    di(2-ethylhexyl) phthalate 193.31
    ethyl propionate 519.24
    nitromethane 664.52
    1,2-diethoxyethane 590.99
    benzonitrile 404.72
    trioctyl phosphate 209.32
    1-bromopropane 784.08
    gamma-valerolactone 1365.26
    n-decanol 384.14
    triethyl phosphate 208.98
    4-methyl-2-pentanol 453.36
    propionitrile 850.0
    vinylene carbonate 517.96
    1,1,2-trichlorotrifluoroethane 505.27
    DMS 414.3
    cumene 290.33
    2-octanol 405.62
    2-hexanone 657.12
    octyl acetate 425.09
    limonene 404.16
    1,2-dimethoxyethane 969.66
    ethyl orthosilicate 213.81
    tributyl phosphate 219.92
    diacetone alcohol 706.74
    N,N-dimethylaniline 400.01
    acrylonitrile 712.54
    aniline 360.3
    1,3-propanediol 342.86
    bromobenzene 494.16
    dibromomethane 776.3
    1,1,2,2-tetrachloroethane 1081.92
    2-methyl-cyclohexyl acetate 417.12
    tetrabutyl urea 281.01
    diisobutyl methanol 360.41
    2-phenylethanol 507.09
    styrene 362.08
    dioctyl adipate 306.78
    dimethyl sulfate 416.54
    ethyl butyrate 510.5
    methyl lactate 318.2
    butyl lactate 318.36
    diethyl carbonate 292.62
    propanediol butyl ether 462.29
    triethyl orthoformate 317.34
    p-tert-butyltoluene 290.26
    methyl 4-tert-butylbenzoate 434.43
    morpholine 1328.48
    tert-butylamine 800.54
    n-dodecanol 314.01
    dimethoxymethane 853.65
    ethylene carbonate 491.38
    cyrene 344.5
    2-ethoxyethyl acetate 414.84
    2-ethylhexyl acetate 577.18
    1,2,4-trichlorobenzene 403.26
    4-methylpyridine 705.48
    dibutyl ether 588.38
    2,6-dimethyl-4-heptanol 360.41
    DEF 709.27
    dimethyl isosorbide 669.92
    tetrachloroethylene 581.3
    eugenol 363.6
    triacetin 363.98
    span 80 396.45
    1,4-butanediol 170.17
    1,1-dichloroethane 1053.71
    2-methyl-1-pentanol 427.87
    methyl formate 417.88
    2-methyl-1-butanol 555.58
    n-decane 173.1
    butyronitrile 929.83
    3,7-dimethyl-1-octanol 484.88
    1-chlorooctane 478.4
    1-chlorotetradecane 203.48
    n-nonane 188.21
    undecane 134.41
    tert-butylcyclohexane 213.04
    cyclooctane 173.7
    cyclopentanol 834.09
    tetrahydropyran 1741.33
    tert-amyl methyl ether 833.11
    2,5,8-trioxanonane 517.51
    1-hexene 802.62
    2-isopropoxyethanol 411.93
    2,2,2-trifluoroethanol 124.55
    methyl butyrate 613.92

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction