2-Phenylphenol

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  • Identifiers

    CAS number
    90-43-7

    Molecular formula
    C12H10O

    SMILES
    C1=CC=C(C=C1)C2=CC=CC=C2O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Phenolic 76.72%
    Medicinal 55.76%
    Spicy 46.23%
    Animal 39.06%
    Smoky 35.75%
    Leathery 35.72%
    Burnt 30.56%
    Metallic 30.05%
    Geranium 29.34%
    Rose 29.18%

     

    Flavor
    Phenolic 63.43%
    Medicinal 43.91%
    Geranium 39.55%
    Plastic 33.24%
    Phenol 32.11%
    Green 32.05%
    Fecal 29.17%
    Animal 26.73%
    Rubber 26.65%
    Guaiacol 26.39%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.1

    pKa est.
    9.3 (weak base)

    Molecular weight
    170.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 131.9 to 135.5 °F (NTP, 1992)
    • 59 °C
    • 56 °C
    • 58-60 °C

    Boiling point

    • 527 °F at 760 mmHg (NTP, 1992)
    • 286 °C
    • 282.00 to 285.00 °C. @ 760.00 mm Hg

    Flash point

    • 146.64 ˚C est.
    • 255 °F (NTP, 1992)
    • 124 °C
    • Value: 138 degree C Type: closed cup
    • 124 °C c.c.

    Solubility expt.

    • less than 0.1 mg/mL at 68.9 °F (NTP, 1992)
    • FORMS SALTS OF WHICH THOSE OF THE ALKALI METALS ARE WATER-SOLUBLE; THE SODIUM SALT CRYSTALLIZES AS A TETRAHYDRATE, SOLUBILITY CIRCA 1.1 KG/KG WATER (35 °C), GIVING A SOLUTION OF PH 12.0-13.5.
    • Soluble in fixed alkali hydroxide solutions and most organic solvents.
    • Soluble in sodium hydroxide
    • Soluble in ethanol, acetone, benzene, chloroform, and ligroin; very soluble in ethyl ether and pyridine.
    • Sol in most organic solvents, including ethanol, ethylene glycol, isopropanol, glycolethers, and polyglycols.
    • For more Solubility (Complete) data for o-Phenylphenol (6 total), please visit the HSDB record page.
    • 0.7 mg/mL at 25 °C
    • Solubility in water, g/l at 20 °C: 0.2 (very poor)
    • insoluble in water
    • moderately soluble (in ethanol)

  • Synonyms

    • 2-Phenylphenol
    • 2-Hydroxybiphenyl
    • 90-43-7
    • O-PHENYLPHENOL
    • Biphenyl-2-ol
    • 2-Biphenylol
    • o-Hydroxybiphenyl
    • 2-Hydroxydiphenyl
    • o-Hydroxydiphenyl
    • o-Phenyl phenol
    • Phenylphenol
    • Biphenylol
    • Orthophenylphenol
    • Orthoxenol
    • o-Diphenylol
    • Dowicide 1
    • Torsite
    • [1,1'-Biphenyl]-2-ol
    • o-Xenol
    • o-Biphenylol
    • Preventol O extra
    • Nectryl
    • Orthohydroxydiphenyl
    • Tumescal OPE
    • (1,1'-Biphenyl)-2-ol
    • ortho-Phenylphenol
    • Remol TRF
    • Phenol, o-phenyl-
    • Tetrosin oe
    • 2-Fenylfenol
    • 2-Hydroxybifenyl
    • o-Xonal
    • Invalon OP
    • 2-Phenyl phenol
    • 1-Hydroxy-2-phenylbenzene
    • Anthrapole 73
    • Biphenyl, 2-hydroxy-
    • 2-hydroxy biphenyl
    • Hydroxdiphenyl
    • o-phenylphenate
    • Usaf ek-2219
    • Kiwi lustr 277
    • 1,1'-Biphenyl-2-ol
    • (1,1-Biphenyl)-2-ol
    • Phenyl-2 phenol
    • Orthophenyl phenol
    • ortho-phenylphenate
    • orthohydroxydipbenyl
    • Dowicide 1 antimicrobial
    • Biphenyl-2-o1
    • o-Phenylphenol, cosmetic grade
    • Dowicide
    • NCI-C50351
    • 2-Fenylfenol [Czech]
    • Hydroxy-2-phenylbenzene
    • Nipacide OPP
    • Caswell No. 623AA
    • OPP [pesticide]
    • 2-Hydroxybifenyl [Czech]
    • NSC 1548
    • 2-Phenylphenol [BSI:ISO]
    • Stellisept
    • CCRIS 1388
    • Rotoline
    • Phenyl-2 phenol [ISO-French]
    • HSDB 1753
    • 2-Hydroxy-1,1'-biphenyl
    • Tetrosin OE-N
    • EINECS 201-993-5
    • EPA Pesticide Chemical Code 064103
    • Amocid (TN)
    • BRN 0606907
    • ORTOFENILFENOL
    • Preventol 3041
    • DTXSID2021151
    • CHEBI:17043
    • AI3-00062
    • D343Z75HT8
    • NSC-1548
    • PHENYLPHENOL, O-
    • ORTHO PHENYL PHENOL
    • O-PHENYLPHENOL [MI]
    • 2-Phenylphenol, BSI, ISO
    • 2-PHENYLPHENOL [ISO]
    • 2-PHENYLPHENOL [FHFI]
    • 2-PHENYLPHENOL [HSDB]
    • CHEMBL108829
    • DTXCID201151
    • FEMA 3959
    • ORTHO-PHENYLPHENOL [IARC]
    • ORTHOPHENYLPHENOL [MART.]
    • EC 201-993-5
    • OPP (pesticide)
    • ORTHOPHENYLPHENOL [WHO-DD]
    • 4-06-00-04579 (Beilstein Handbook Reference)
    • MFCD00002208
    • ORTHOPHENYL PHENOL (E 231)
    • Dowicide A
    • E231
    • Lyorthol
    • 2-hydroxybifenyl (Czech)
    • Tumescal 0PE
    • Phenyl-2 phenol (ISO-French)
    • ORTHO-PHENYLPHENOL (IARC)
    • ORTHOPHENYLPHENOL (MART.)
    • sodium o-phenylphenoate
    • Hydroxybiphenyl
    • Xenol
    • CAS-90-43-7
    • Kiwiydiphenyl
    • oBiphenylol
    • oDiphenylol
    • Manusept
    • 2phenylphenol
    • Amocid
    • 2Hydroxybifenyl
    • oHydroxybiphenyl
    • oHydroxydiphenyl
    • oPhenyl phenol
    • UNII-D343Z75HT8
    • 2Biphenylol
    • 2Fenylfenol
    • 2hydroxybiphenyl
    • Biphenyl2ol
    • o-Fenilfenol
    • o-phenyl-phenol
    • 2Hydroxydiphenyl
    • Phenol, ophenyl

  • Applications

    2-Phenylphenol (CAS 90-43-7) is used as an antimicrobial/disinfectant in household and industrial cleaning products; serves as a chemical intermediate in the synthesis of dyes and pigments for coatings and inks; acts as a precursor for phenolic resins and other polymer-related compounds; and functions as a process intermediate for various specialty chemicals in the chemical industry.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 558.21
    methanol 372.19
    isopropanol 400.06
    water 0.61
    ethyl acetate 555.65
    n-propanol 411.27
    acetone 1124.93
    n-butanol 326.01
    acetonitrile 787.53
    DMF 1655.69
    toluene 138.3
    isobutanol 244.07
    1,4-dioxane 1170.73
    methyl acetate 521.67
    THF 1378.33
    2-butanone 695.58
    n-pentanol 189.7
    sec-butanol 242.06
    n-hexane 39.47
    ethylene glycol 91.72
    NMP 575.23
    cyclohexane 45.59
    DMSO 1568.05
    n-butyl acetate 372.05
    n-octanol 167.4
    chloroform 794.01
    n-propyl acetate 366.16
    acetic acid 339.23
    dichloromethane 840.59
    cyclohexanone 769.75
    propylene glycol 114.8
    isopropyl acetate 265.24
    DMAc 709.99
    2-ethoxyethanol 249.27
    isopentanol 211.84
    n-heptane 54.35
    ethyl formate 466.32
    1,2-dichloroethane 827.51
    n-hexanol 265.1
    2-methoxyethanol 545.0
    isobutyl acetate 199.52
    tetrachloromethane 77.14
    n-pentyl acetate 188.59
    transcutol 757.03
    n-heptanol 154.25
    ethylbenzene 115.98
    MIBK 271.56
    2-propoxyethanol 366.41
    tert-butanol 338.17
    MTBE 278.6
    2-butoxyethanol 223.64
    propionic acid 342.02
    o-xylene 87.32
    formic acid 62.42
    diethyl ether 531.77
    m-xylene 97.49
    p-xylene 113.91
    chlorobenzene 234.89
    dimethyl carbonate 246.55
    n-octane 28.62
    formamide 297.72
    cyclopentanone 1074.54
    2-pentanone 605.32
    anisole 285.06
    cyclopentyl methyl ether 394.8
    gamma-butyrolactone 1063.01
    1-methoxy-2-propanol 393.73
    pyridine 762.09
    3-pentanone 367.57
    furfural 581.72
    n-dodecane 23.64
    diethylene glycol 213.85
    diisopropyl ether 105.53
    tert-amyl alcohol 216.17
    acetylacetone 468.07
    n-hexadecane 26.8
    acetophenone 242.0
    methyl propionate 427.07
    isopentyl acetate 249.8
    trichloroethylene 1076.61
    n-nonanol 142.56
    cyclohexanol 209.45
    benzyl alcohol 164.8
    2-ethylhexanol 160.09
    isooctanol 122.55
    dipropyl ether 328.93
    1,2-dichlorobenzene 183.45
    ethyl lactate 131.02
    propylene carbonate 499.04
    n-methylformamide 704.84
    2-pentanol 191.04
    n-pentane 29.79
    1-propoxy-2-propanol 289.23
    1-methoxy-2-propyl acetate 254.25
    2-(2-methoxypropoxy) propanol 180.36
    mesitylene 65.95
    ε-caprolactone 520.53
    p-cymene 71.98
    epichlorohydrin 1165.21
    1,1,1-trichloroethane 420.19
    2-aminoethanol 187.4
    morpholine-4-carbaldehyde 558.2
    sulfolane 975.73
    2,2,4-trimethylpentane 15.03
    2-methyltetrahydrofuran 697.59
    n-hexyl acetate 283.17
    isooctane 17.05
    2-(2-butoxyethoxy)ethanol 282.52
    sec-butyl acetate 173.77
    tert-butyl acetate 221.3
    decalin 30.64
    glycerin 137.22
    diglyme 611.15
    acrylic acid 248.27
    isopropyl myristate 112.4
    n-butyric acid 474.69
    acetyl acetate 235.56
    di(2-ethylhexyl) phthalate 72.78
    ethyl propionate 285.55
    nitromethane 939.2
    1,2-diethoxyethane 363.87
    benzonitrile 254.21
    trioctyl phosphate 67.82
    1-bromopropane 351.53
    gamma-valerolactone 876.39
    n-decanol 107.58
    triethyl phosphate 91.01
    4-methyl-2-pentanol 108.9
    propionitrile 552.64
    vinylene carbonate 414.35
    1,1,2-trichlorotrifluoroethane 430.57
    DMS 194.34
    cumene 77.41
    2-octanol 110.0
    2-hexanone 359.71
    octyl acetate 139.47
    limonene 103.75
    1,2-dimethoxyethane 713.28
    ethyl orthosilicate 83.6
    tributyl phosphate 78.44
    diacetone alcohol 268.2
    N,N-dimethylaniline 157.48
    acrylonitrile 664.54
    aniline 209.79
    1,3-propanediol 297.7
    bromobenzene 213.27
    dibromomethane 547.34
    1,1,2,2-tetrachloroethane 813.82
    2-methyl-cyclohexyl acetate 142.47
    tetrabutyl urea 116.96
    diisobutyl methanol 99.72
    2-phenylethanol 165.57
    styrene 144.22
    dioctyl adipate 137.64
    dimethyl sulfate 305.41
    ethyl butyrate 276.51
    methyl lactate 174.05
    butyl lactate 130.16
    diethyl carbonate 160.04
    propanediol butyl ether 184.45
    triethyl orthoformate 139.85
    p-tert-butyltoluene 65.95
    methyl 4-tert-butylbenzoate 177.13
    morpholine 1046.0
    tert-butylamine 190.75
    n-dodecanol 84.28
    dimethoxymethane 804.1
    ethylene carbonate 386.74
    cyrene 159.8
    2-ethoxyethyl acetate 224.27
    2-ethylhexyl acetate 182.4
    1,2,4-trichlorobenzene 203.98
    4-methylpyridine 489.7
    dibutyl ether 237.52
    2,6-dimethyl-4-heptanol 99.72
    DEF 537.63
    dimethyl isosorbide 280.49
    tetrachloroethylene 444.74
    eugenol 165.3
    triacetin 199.14
    span 80 153.11
    1,4-butanediol 89.94
    1,1-dichloroethane 632.52
    2-methyl-1-pentanol 144.54
    methyl formate 523.56
    2-methyl-1-butanol 182.25
    n-decane 40.39
    butyronitrile 525.29
    3,7-dimethyl-1-octanol 121.93
    1-chlorooctane 138.46
    1-chlorotetradecane 52.96
    n-nonane 41.13
    undecane 30.22
    tert-butylcyclohexane 28.93
    cyclooctane 19.31
    cyclopentanol 286.42
    tetrahydropyran 908.56
    tert-amyl methyl ether 172.7
    2,5,8-trioxanonane 352.88
    1-hexene 162.82
    2-isopropoxyethanol 181.21
    2,2,2-trifluoroethanol 115.32
    methyl butyrate 411.92

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction