2-(Phenoxymethyl)furan

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  • Identifiers

    CAS number
    4437-23-4

    Molecular formula
    C11H10O2

    SMILES
    C1=CC=C(C=C1)OCC2=CC=CO2

    Safety labels

  • Odor profile

    Fragrance
    Earthy 48.49%
    Floral 45.78%
    Green 41.48%
    Fruity 36.06%
    Burnt 35.89%
    Aromatic 35.33%
    Metallic 34.5%
    Sweet 33.45%
    Rose 32.46%
    Mushroom 30.93%

     

    Flavor
    Sweet 70.57%
    Fruity 52.99%
    Coffee 38.79%
    Almond 37.02%
    Earthy 36.34%
    Chocolate 34.91%
    Green 34.0%
    Nutty 33.48%
    Balsam 32.65%
    Rose 32.18%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    5.73 (weak acid)

    Molecular weight
    174.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    260°C

    Flash point

    • 101.01 ˚C est.

  • Synonyms

    • 2-(phenoxymethyl)furan
    • Furan, 2-(phenoxymethyl)-
    • 4437-23-4
    • 2-phenoxymethyl furan
    • Furfuryl-phenyl-ather
    • (2-furylmethoxy)benzene
    • SCHEMBL920785
    • SCHEMBL921876
    • SCHEMBL1607082
    • SCHEMBL5759284
    • SCHEMBL27282809
    • DTXSID90394788
    • AKOS002228807
    • HS-5810
    • ST50112641
    • 4437-23-4

  • Applications

    2-(Phenoxymethyl)furan (CAS 4437-23-4) is used as an organic synthesis intermediate to access substituted furan derivatives and compounds bearing the phenoxymethyl group. It may serve as a precursor in fragrance and flavor chemistry, providing a route to aroma-related intermediates. In pharmaceutical development, it can act as a starting material for heterocyclic intermediates based on the furan ring. In materials science, it is explored as a functional building block for specialty polymers and for coatings/inks formulations. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 137.42
    methanol 161.81
    isopropanol 67.32
    water 0.25
    ethyl acetate 217.86
    n-propanol 103.15
    acetone 27.11
    n-butanol 82.91
    acetonitrile 188.36
    DMF 19.7
    toluene 100.34
    isobutanol 58.35
    1,4-dioxane 490.2
    methyl acetate 150.36
    THF 265.53
    2-butanone 75.46
    n-pentanol 77.21
    sec-butanol 91.16
    n-hexane 10.99
    ethylene glycol 51.66
    NMP 15.61
    cyclohexane 28.89
    DMSO 195.69
    n-butyl acetate 75.24
    n-octanol 33.34
    chloroform 558.2
    n-propyl acetate 87.11
    acetic acid 135.75
    dichloromethane 629.46
    cyclohexanone 58.36
    propylene glycol 70.18
    isopropyl acetate 85.17
    DMAc 73.28
    2-ethoxyethanol 198.35
    isopentanol 74.91
    n-heptane 14.27
    ethyl formate 64.43
    1,2-dichloroethane 322.52
    n-hexanol 61.88
    2-methoxyethanol 203.51
    isobutyl acetate 58.8
    tetrachloromethane 31.29
    n-pentyl acetate 38.22
    transcutol 942.25
    n-heptanol 26.72
    ethylbenzene 60.76
    MIBK 63.98
    2-propoxyethanol 133.76
    tert-butanol 98.09
    MTBE 114.89
    2-butoxyethanol 70.93
    propionic acid 83.85
    o-xylene 58.42
    formic acid 50.41
    diethyl ether 234.84
    m-xylene 51.45
    p-xylene 59.24
    chlorobenzene 93.54
    dimethyl carbonate 50.76
    n-octane 6.0
    formamide 87.55
    cyclopentanone 45.41
    2-pentanone 51.41
    anisole 158.61
    cyclopentyl methyl ether 84.53
    gamma-butyrolactone 89.58
    1-methoxy-2-propanol 139.14
    pyridine 284.3
    3-pentanone 64.51
    furfural 135.52
    n-dodecane 6.34
    diethylene glycol 127.92
    diisopropyl ether 43.15
    tert-amyl alcohol 99.24
    acetylacetone 105.85
    n-hexadecane 7.11
    acetophenone 97.93
    methyl propionate 96.45
    isopentyl acetate 76.79
    trichloroethylene 465.69
    n-nonanol 36.11
    cyclohexanol 65.77
    benzyl alcohol 92.56
    2-ethylhexanol 51.58
    isooctanol 27.06
    dipropyl ether 93.96
    1,2-dichlorobenzene 86.36
    ethyl lactate 51.26
    propylene carbonate 73.4
    n-methylformamide 27.82
    2-pentanol 59.33
    n-pentane 9.61
    1-propoxy-2-propanol 95.16
    1-methoxy-2-propyl acetate 105.25
    2-(2-methoxypropoxy) propanol 145.19
    mesitylene 34.09
    ε-caprolactone 84.42
    p-cymene 36.11
    epichlorohydrin 283.57
    1,1,1-trichloroethane 172.0
    2-aminoethanol 92.51
    morpholine-4-carbaldehyde 107.84
    sulfolane 92.8
    2,2,4-trimethylpentane 10.28
    2-methyltetrahydrofuran 146.86
    n-hexyl acetate 61.76
    isooctane 6.89
    2-(2-butoxyethoxy)ethanol 186.43
    sec-butyl acetate 70.21
    tert-butyl acetate 89.35
    decalin 17.61
    glycerin 89.58
    diglyme 368.06
    acrylic acid 78.62
    isopropyl myristate 41.94
    n-butyric acid 102.4
    acetyl acetate 121.74
    di(2-ethylhexyl) phthalate 39.72
    ethyl propionate 90.96
    nitromethane 165.6
    1,2-diethoxyethane 228.28
    benzonitrile 86.5
    trioctyl phosphate 21.83
    1-bromopropane 160.6
    gamma-valerolactone 95.83
    n-decanol 29.23
    triethyl phosphate 52.01
    4-methyl-2-pentanol 43.15
    propionitrile 128.15
    vinylene carbonate 79.38
    1,1,2-trichlorotrifluoroethane 157.84
    DMS 83.31
    cumene 40.79
    2-octanol 18.87
    2-hexanone 69.69
    octyl acetate 42.28
    limonene 45.64
    1,2-dimethoxyethane 305.71
    ethyl orthosilicate 53.23
    tributyl phosphate 33.53
    diacetone alcohol 95.78
    N,N-dimethylaniline 89.8
    acrylonitrile 140.26
    aniline 98.01
    1,3-propanediol 110.08
    bromobenzene 107.9
    dibromomethane 365.94
    1,1,2,2-tetrachloroethane 341.56
    2-methyl-cyclohexyl acetate 69.64
    tetrabutyl urea 40.86
    diisobutyl methanol 40.84
    2-phenylethanol 72.23
    styrene 78.73
    dioctyl adipate 69.26
    dimethyl sulfate 57.82
    ethyl butyrate 85.74
    methyl lactate 53.01
    butyl lactate 37.22
    diethyl carbonate 76.83
    propanediol butyl ether 72.79
    triethyl orthoformate 72.19
    p-tert-butyltoluene 33.04
    methyl 4-tert-butylbenzoate 87.39
    morpholine 374.53
    tert-butylamine 64.28
    n-dodecanol 25.15
    dimethoxymethane 102.63
    ethylene carbonate 66.79
    cyrene 84.72
    2-ethoxyethyl acetate 85.01
    2-ethylhexyl acetate 59.45
    1,2,4-trichlorobenzene 102.32
    4-methylpyridine 106.34
    dibutyl ether 79.46
    2,6-dimethyl-4-heptanol 40.84
    DEF 64.23
    dimethyl isosorbide 177.3
    tetrachloroethylene 208.97
    eugenol 84.99
    triacetin 106.16
    span 80 82.32
    1,4-butanediol 45.85
    1,1-dichloroethane 188.43
    2-methyl-1-pentanol 78.97
    methyl formate 26.02
    2-methyl-1-butanol 71.35
    n-decane 9.47
    butyronitrile 92.56
    3,7-dimethyl-1-octanol 50.82
    1-chlorooctane 32.95
    1-chlorotetradecane 17.39
    n-nonane 8.52
    undecane 7.39
    tert-butylcyclohexane 14.5
    cyclooctane 11.02
    cyclopentanol 46.27
    tetrahydropyran 253.44
    tert-amyl methyl ether 93.67
    2,5,8-trioxanonane 294.67
    1-hexene 46.68
    2-isopropoxyethanol 122.65
    2,2,2-trifluoroethanol 40.67
    methyl butyrate 89.39

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction