2-Palmitoylglycerol

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  • Identifiers

    CAS number
    23470-00-0

    Molecular formula
    C19H38O4

    SMILES
    CCCCCCCCCCCCCCCC(=O)OC(CO)CO

    Safety labels

  • Odor profile

    Fragrance
    Waxy 65.4%
    Fatty 60.33%
    Oily 44.5%
    Odorless 39.42%
    Creamy 26.9%
    Buttery 24.27%
    Milky 23.05%
    Sweet 22.94%
    Dairy 21.85%
    Coconut 20.1%

     

    Flavor
    Waxy 58.52%
    Fatty 48.56%
    Oily 43.84%
    Mild 42.46%
    Soapy 34.37%
    Bland 32.68%
    Creamy 29.68%
    Odorless 29.65%
    Fat 29.21%
    Coconut 29.15%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.1

    pKa est.
    6.81 (neutral)

    Molecular weight
    330.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    433°C

    Flash point

    • 194.71 ˚C est.

  • Synonyms

    • 2-Palmitoylglycerol
    • 2-Monopalmitin
    • 23470-00-0
    • 1,3-dihydroxypropan-2-yl hexadecanoate
    • 2-Monopalmitoylglycerol
    • 2-palmitoyl-glycerol
    • 2-Hexadecanoyl glycerol
    • Glycerol, 2-palmitate
    • Palmitin, 2-mono
    • Glyceryl 2-palmitate
    • Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester
    • 21I29V2935
    • CHEBI:75455
    • DTXSID30178024
    • 2-Palm-Gl
    • RefChem:910191
    • GlyTouCan:G78009RD
    • DTXCID60100515
    • G78009RD
    • 2-Palmitoyl-rac-glycerol
    • 1,3-dihydroxypropan-2-yl palmitate
    • Palmitin, 2-mono-
    • 2-Monopalmitoyl-sn-glycerol
    • .beta.-Monopalmitin
    • 2-hexadecanoylglycerol
    • 2-hexadecanoyl-sn-glycerol
    • MG(0:0/16:0/0:0)
    • beta-Monopalmitin
    • 2-O-palmitoylglycerol
    • 2-Monohexadecanoylglycerol
    • UNII-21I29V2935
    • Glycerol 2-hexadecanoate
    • Glycerol .beta.-palmitate
    • 2-hexadecanoyl-rac-glycerol
    • palmitic acid glycerol ester
    • SCHEMBL133614
    • QSPL 170
    • GLYCERYL 2-HEXADECANOATE
    • Palmitic acid beta-monoglyceride
    • CHEMBL1317070
    • 2-Palmitoylmonoglycerol (2-PG)
    • Hexadecanoic Acid 2-Hydroxy-1-(hydroxymethyl)ethyl Ester
    • hexadecanoic acid, 2-hydroxy-1-
    • 1,3-dihydroxypropan-2-ylpalmitate
    • BDBM197166
    • Palmitic acid .beta.-monoglyceride
    • 1,3-Dihydroxy-2-propanyl palmitate
    • LMGL01010025
    • MFCD00058513
    • MSK175619
    • AKOS015951327
    • CS-W014504
    • EBC-618575
    • HY-W013788
    • 2-Palmitoylglycerol, analytical standard
    • NCGC00092337-01
    • DA-49455
    • FP167393
    • MS-24972
    • PD017581
    • MAG(0:0/16:0)
    • 2-Hydroxy-1-(hydroxymethyl)ethyl palmitate
    • NS00051368
    • G12159
    • MG(0:0/16:0)
    • P-1120
    • [2-hydroxy-1-(hydroxymethyl)ethyl] hexadecanoate
    • MG (0:0/16:0/0:0)
    • Q27145323
    • Hexadecanoic acid,2-hydroxy-1-(hydroxymethyl)ethyl ester
    • VLP
    • 23470-00-0

  • Applications

    2-Palmitoylglycerol (CAS 23470-00-0) is a lipidic monoacylglyceride commonly used in formulations as an emollient and surfactant; in cosmetics and personal care it acts as an emollient, conditioning agent, and emulsifier that helps stabilize emulsions and improve texture. It may be used as a processing aid or carrier in pharmaceutical lipid-based drug delivery systems, functioning as a solubilizer or viscosity modifier. In the food processing sector, monoacylglycerides and related MAGs serve as emulsifiers and processing aids, and this compound may be used in similar roles within lipid-containing formulations. In cleaning and household products, it can act as a surfactant and emulsifier to assist cleaning performance. In coatings, inks, and industrial formulations, it may serve as a lubricating additive or plasticizer to improve processing and film formation. In agricultural formulations, it can be used to improve dispersion and compatibility of active ingredients.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.14
    methanol 41.71
    isopropanol 25.8
    water 0.09
    ethyl acetate 119.19
    n-propanol 30.69
    acetone 101.64
    n-butanol 33.9
    acetonitrile 40.81
    DMF 226.22
    toluene 35.18
    isobutanol 33.86
    1,4-dioxane 135.62
    methyl acetate 90.29
    THF 424.85
    2-butanone 119.28
    n-pentanol 36.32
    sec-butanol 38.22
    n-hexane 7.01
    ethylene glycol 4.75
    NMP 483.08
    cyclohexane 40.65
    DMSO 530.63
    n-butyl acetate 143.74
    n-octanol 47.96
    chloroform 280.19
    n-propyl acetate 191.29
    acetic acid 77.7
    dichloromethane 320.09
    cyclohexanone 428.9
    propylene glycol 12.61
    isopropyl acetate 132.04
    DMAc 390.18
    2-ethoxyethanol 112.39
    isopentanol 55.16
    n-heptane 8.65
    ethyl formate 72.33
    1,2-dichloroethane 264.27
    n-hexanol 31.85
    2-methoxyethanol 112.32
    isobutyl acetate 120.84
    tetrachloromethane 70.68
    n-pentyl acetate 237.64
    transcutol 497.55
    n-heptanol 44.06
    ethylbenzene 33.67
    MIBK 142.83
    2-propoxyethanol 97.66
    tert-butanol 78.85
    MTBE 93.25
    2-butoxyethanol 141.61
    propionic acid 67.33
    o-xylene 45.75
    formic acid 21.9
    diethyl ether 55.95
    m-xylene 35.02
    p-xylene 52.09
    chlorobenzene 79.44
    dimethyl carbonate 45.91
    n-octane 5.67
    formamide 50.59
    cyclopentanone 434.88
    2-pentanone 133.36
    anisole 83.47
    cyclopentyl methyl ether 186.88
    gamma-butyrolactone 418.73
    1-methoxy-2-propanol 119.37
    pyridine 140.41
    3-pentanone 112.22
    furfural 297.38
    n-dodecane 3.74
    diethylene glycol 52.61
    diisopropyl ether 35.07
    tert-amyl alcohol 82.98
    acetylacetone 219.05
    n-hexadecane 4.51
    acetophenone 141.4
    methyl propionate 103.17
    isopentyl acetate 153.31
    trichloroethylene 411.44
    n-nonanol 48.4
    cyclohexanol 103.71
    benzyl alcohol 63.27
    2-ethylhexanol 41.77
    isooctanol 50.42
    dipropyl ether 72.91
    1,2-dichlorobenzene 118.07
    ethyl lactate 82.08
    propylene carbonate 231.0
    n-methylformamide 75.52
    2-pentanol 33.75
    n-pentane 4.69
    1-propoxy-2-propanol 108.17
    1-methoxy-2-propyl acetate 148.71
    2-(2-methoxypropoxy) propanol 117.39
    mesitylene 32.82
    ε-caprolactone 355.81
    p-cymene 33.47
    epichlorohydrin 379.07
    1,1,1-trichloroethane 254.18
    2-aminoethanol 16.7
    morpholine-4-carbaldehyde 310.75
    sulfolane 845.83
    2,2,4-trimethylpentane 8.7
    2-methyltetrahydrofuran 245.34
    n-hexyl acetate 195.07
    isooctane 4.85
    2-(2-butoxyethoxy)ethanol 164.56
    sec-butyl acetate 137.16
    tert-butyl acetate 201.81
    decalin 18.38
    glycerin 30.52
    diglyme 411.8
    acrylic acid 51.31
    isopropyl myristate 57.25
    n-butyric acid 146.76
    acetyl acetate 101.71
    di(2-ethylhexyl) phthalate 54.2
    ethyl propionate 142.82
    nitromethane 195.61
    1,2-diethoxyethane 166.17
    benzonitrile 88.03
    trioctyl phosphate 44.1
    1-bromopropane 105.06
    gamma-valerolactone 560.09
    n-decanol 29.47
    triethyl phosphate 87.21
    4-methyl-2-pentanol 34.81
    propionitrile 45.76
    vinylene carbonate 168.19
    1,1,2-trichlorotrifluoroethane 311.32
    DMS 108.22
    cumene 30.14
    2-octanol 42.85
    2-hexanone 146.09
    octyl acetate 75.12
    limonene 60.04
    1,2-dimethoxyethane 271.84
    ethyl orthosilicate 86.05
    tributyl phosphate 62.12
    diacetone alcohol 207.95
    N,N-dimethylaniline 68.64
    acrylonitrile 55.86
    aniline 46.28
    1,3-propanediol 35.47
    bromobenzene 90.03
    dibromomethane 196.17
    1,1,2,2-tetrachloroethane 435.8
    2-methyl-cyclohexyl acetate 130.08
    tetrabutyl urea 93.47
    diisobutyl methanol 36.6
    2-phenylethanol 56.07
    styrene 39.12
    dioctyl adipate 110.73
    dimethyl sulfate 139.17
    ethyl butyrate 147.05
    methyl lactate 66.27
    butyl lactate 154.35
    diethyl carbonate 84.95
    propanediol butyl ether 113.21
    triethyl orthoformate 117.83
    p-tert-butyltoluene 32.33
    methyl 4-tert-butylbenzoate 162.18
    morpholine 203.65
    tert-butylamine 45.88
    n-dodecanol 20.23
    dimethoxymethane 111.94
    ethylene carbonate 161.48
    cyrene 152.68
    2-ethoxyethyl acetate 236.75
    2-ethylhexyl acetate 124.13
    1,2,4-trichlorobenzene 142.28
    4-methylpyridine 127.11
    dibutyl ether 93.53
    2,6-dimethyl-4-heptanol 36.6
    DEF 219.81
    dimethyl isosorbide 263.27
    tetrachloroethylene 286.96
    eugenol 126.84
    triacetin 223.51
    span 80 109.74
    1,4-butanediol 17.88
    1,1-dichloroethane 171.61
    2-methyl-1-pentanol 50.37
    methyl formate 56.72
    2-methyl-1-butanol 48.37
    n-decane 8.39
    butyronitrile 56.54
    3,7-dimethyl-1-octanol 50.71
    1-chlorooctane 48.56
    1-chlorotetradecane 13.73
    n-nonane 7.97
    undecane 5.15
    tert-butylcyclohexane 12.8
    cyclooctane 9.83
    cyclopentanol 110.46
    tetrahydropyran 196.17
    tert-amyl methyl ether 94.24
    2,5,8-trioxanonane 226.23
    1-hexene 22.9
    2-isopropoxyethanol 97.35
    2,2,2-trifluoroethanol 52.79
    methyl butyrate 228.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction