2-Oxo-3-ethyl-4-butanolide

Overview IFRA Request a quote

  • Identifiers

    CAS number
    923291-29-6

    Molecular formula
    C6H8O3

    SMILES
    CCC1COC(=O)C1=O

    Safety labels

  • Odor profile

    Fragrance
    Caramellic 83.43%
    Sweet 69.05%
    Burnt 56.53%
    Nutty 38.41%
    Buttery 38.39%
    Coumarinic 37.47%
    Fruity 35.42%
    Coffee 32.21%
    Coconut 31.0%
    Tobacco 30.4%

     

    Flavor
    Caramel 57.09%
    Sweet 52.15%
    Maple 40.93%
    Buttery 33.42%
    Sugar 32.58%
    Candy 27.33%
    Tonka 26.33%
    Coconut 25.95%
    Creamy 25.19%
    Coumarin 24.24%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    7.77 (neutral)

    Molecular weight
    128.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    267°C

    Flash point

    • 94.26 ˚C est.

    Solubility expt.

    • Practically insoluble or insoluble in water
    • Soluble (in ethanol)

  • Synonyms

    • 2-Oxo-3-ethyl-4-butanolide
    • FEMA No. 4460
    • 2,3-Furandione, 4-ethyldihydro-
    • UNII-028177L89R
    • 923291-29-6
    • 028177L89R
    • 4-ETHYLDIHYDRO-2,3-FURANDIONE
    • RefChem:88914
    • 4-ethyloxolane-2,3-dione
    • SCHEMBL3092802
    • DTXSID00919244
    • Q27231505
    • 923291-29-6

  • Applications

    2-Oxo-3-ethyl-4-butanolide (CAS 923291-29-6) is primarily used as a chemical intermediate in fragrance and flavor chemistry. It is commonly evaluated as a building block for aroma compounds and may serve as a fragrance ingredient or odor-active intermediate in perfumery and in cosmetics/personal care formulations. In polymer and plastics contexts, it can act as a precursor for specialty polyesters via lactone-ring opening polymerization. In industrial manufacturing, it may function as a processing aid or specialty solvent in the synthesis of higher-value chemicals. In coatings and inks, it is explored as an intermediate for specialty materials or as a monomer component in tailored polyester systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 209.94
    methanol 339.13
    isopropanol 154.7
    water 7.04
    ethyl acetate 213.83
    n-propanol 152.84
    acetone 334.87
    n-butanol 156.5
    acetonitrile 281.16
    DMF 692.79
    toluene 71.09
    isobutanol 116.74
    1,4-dioxane 346.24
    methyl acetate 332.34
    THF 287.25
    2-butanone 235.89
    n-pentanol 112.17
    sec-butanol 156.14
    n-hexane 5.5
    ethylene glycol 146.48
    NMP 364.06
    cyclohexane 10.5
    DMSO 547.9
    n-butyl acetate 141.43
    n-octanol 103.6
    chloroform 417.51
    n-propyl acetate 131.21
    acetic acid 419.79
    dichloromethane 418.09
    cyclohexanone 228.3
    propylene glycol 114.67
    isopropyl acetate 116.63
    DMAc 462.25
    2-ethoxyethanol 288.24
    isopentanol 157.75
    n-heptane 5.45
    ethyl formate 213.54
    1,2-dichloroethane 320.24
    n-hexanol 117.99
    2-methoxyethanol 514.92
    isobutyl acetate 69.78
    tetrachloromethane 48.73
    n-pentyl acetate 110.61
    transcutol 1114.12
    n-heptanol 76.48
    ethylbenzene 54.53
    MIBK 118.01
    2-propoxyethanol 247.98
    tert-butanol 213.41
    MTBE 141.46
    2-butoxyethanol 194.29
    propionic acid 212.14
    o-xylene 70.81
    formic acid 334.45
    diethyl ether 112.69
    m-xylene 64.17
    p-xylene 73.97
    chlorobenzene 172.96
    dimethyl carbonate 121.03
    n-octane 5.25
    formamide 544.62
    cyclopentanone 237.01
    2-pentanone 168.81
    anisole 154.06
    cyclopentyl methyl ether 100.66
    gamma-butyrolactone 345.48
    1-methoxy-2-propanol 295.01
    pyridine 294.13
    3-pentanone 114.9
    furfural 510.47
    n-dodecane 6.87
    diethylene glycol 307.33
    diisopropyl ether 36.57
    tert-amyl alcohol 198.98
    acetylacetone 256.25
    n-hexadecane 7.86
    acetophenone 168.42
    methyl propionate 185.13
    isopentyl acetate 135.46
    trichloroethylene 664.03
    n-nonanol 87.06
    cyclohexanol 127.67
    benzyl alcohol 158.91
    2-ethylhexanol 74.69
    isooctanol 67.53
    dipropyl ether 43.9
    1,2-dichlorobenzene 176.58
    ethyl lactate 104.09
    propylene carbonate 216.18
    n-methylformamide 400.74
    2-pentanol 104.76
    n-pentane 6.58
    1-propoxy-2-propanol 158.98
    1-methoxy-2-propyl acetate 157.1
    2-(2-methoxypropoxy) propanol 221.2
    mesitylene 46.69
    ε-caprolactone 237.21
    p-cymene 39.56
    epichlorohydrin 458.85
    1,1,1-trichloroethane 244.12
    2-aminoethanol 181.44
    morpholine-4-carbaldehyde 490.97
    sulfolane 427.45
    2,2,4-trimethylpentane 8.2
    2-methyltetrahydrofuran 178.4
    n-hexyl acetate 185.6
    isooctane 6.94
    2-(2-butoxyethoxy)ethanol 334.49
    sec-butyl acetate 84.53
    tert-butyl acetate 137.81
    decalin 11.38
    glycerin 228.98
    diglyme 582.42
    acrylic acid 251.92
    isopropyl myristate 60.69
    n-butyric acid 231.82
    acetyl acetate 152.52
    di(2-ethylhexyl) phthalate 73.16
    ethyl propionate 111.89
    nitromethane 831.99
    1,2-diethoxyethane 218.12
    benzonitrile 203.94
    trioctyl phosphate 51.6
    1-bromopropane 109.2
    gamma-valerolactone 420.83
    n-decanol 65.27
    triethyl phosphate 60.99
    4-methyl-2-pentanol 77.07
    propionitrile 176.3
    vinylene carbonate 261.91
    1,1,2-trichlorotrifluoroethane 381.13
    DMS 165.3
    cumene 43.11
    2-octanol 67.16
    2-hexanone 115.58
    octyl acetate 85.41
    limonene 47.29
    1,2-dimethoxyethane 391.2
    ethyl orthosilicate 54.4
    tributyl phosphate 62.71
    diacetone alcohol 213.92
    N,N-dimethylaniline 102.27
    acrylonitrile 307.37
    aniline 138.3
    1,3-propanediol 261.06
    bromobenzene 158.5
    dibromomethane 230.69
    1,1,2,2-tetrachloroethane 467.27
    2-methyl-cyclohexyl acetate 79.58
    tetrabutyl urea 87.17
    diisobutyl methanol 53.31
    2-phenylethanol 141.79
    styrene 70.46
    dioctyl adipate 86.55
    dimethyl sulfate 210.59
    ethyl butyrate 91.31
    methyl lactate 154.61
    butyl lactate 106.67
    diethyl carbonate 83.5
    propanediol butyl ether 232.26
    triethyl orthoformate 70.35
    p-tert-butyltoluene 39.32
    methyl 4-tert-butylbenzoate 146.38
    morpholine 333.65
    tert-butylamine 106.44
    n-dodecanol 49.24
    dimethoxymethane 262.27
    ethylene carbonate 180.55
    cyrene 162.29
    2-ethoxyethyl acetate 189.96
    2-ethylhexyl acetate 96.92
    1,2,4-trichlorobenzene 206.32
    4-methylpyridine 247.97
    dibutyl ether 77.87
    2,6-dimethyl-4-heptanol 53.31
    DEF 254.52
    dimethyl isosorbide 261.89
    tetrachloroethylene 304.89
    eugenol 187.89
    triacetin 165.83
    span 80 152.31
    1,4-butanediol 118.28
    1,1-dichloroethane 255.49
    2-methyl-1-pentanol 122.75
    methyl formate 343.36
    2-methyl-1-butanol 134.74
    n-decane 9.72
    butyronitrile 152.88
    3,7-dimethyl-1-octanol 106.1
    1-chlorooctane 53.42
    1-chlorotetradecane 23.21
    n-nonane 8.38
    undecane 8.12
    tert-butylcyclohexane 10.5
    cyclooctane 5.03
    cyclopentanol 120.38
    tetrahydropyran 158.92
    tert-amyl methyl ether 111.57
    2,5,8-trioxanonane 378.96
    1-hexene 27.68
    2-isopropoxyethanol 184.67
    2,2,2-trifluoroethanol 198.48
    methyl butyrate 160.91

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction