2-Octyldodecanol

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  • Identifiers

    CAS number
    5333-42-6

    Molecular formula
    C20H42O

    SMILES
    CCCCCCCCCCC(CCCCCCCC)CO

    Safety labels

  • Odor profile

    Fragrance
    Waxy 69.93%
    Fatty 53.12%
    Oily 50.78%
    Fruity 29.71%
    Floral 25.5%
    Fresh 25.4%
    Clean 25.19%
    Odorless 25.05%
    Citrus 23.56%
    Balsamic 23.34%

     

    Flavor
    Waxy 50.12%
    Mild 34.04%
    Alkane 30.82%
    Bland 28.39%
    Fatty 26.8%
    Fat 24.65%
    Flower 24.55%
    Wax 24.14%
    Delicate 24.11%
    Faint 24.09%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.2

    pKa est.
    7.19 (neutral)

    Molecular weight
    298.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    369°C

    Flash point

    • 165.76 ˚C est.

  • Synonyms

    • 2-Octyl-1-dodecanol
    • 5333-42-6
    • Octyldodecanol
    • 2-Octyldodecanol
    • 1-DODECANOL, 2-OCTYL-
    • 2-Octyldodecyl alcohol
    • Octyl dodecanol
    • NSC-2405
    • DTXSID3036288
    • 461N1O614Y
    • DTXCID1016288
    • RefChem:167911
    • 226-242-9
    • 2-Octyldodecan-1-ol
    • Standamul G
    • 2-Octyl dodecanol
    • Isofol 20
    • Kalcohl 200G
    • Rilanit G 20
    • Exxal 20
    • 2-Octyldodecane-1-ol
    • 2-n-octyl-1-dodecanol
    • MFCD01310428
    • NSC 2405
    • NCGC00166213-01
    • 8039-11-0
    • Kalcohl 200GD
    • 2-octildodecanol
    • Guerbet C20
    • Risonol 20SP
    • CAS-5333-42-6
    • Octyldodecanol [NF]
    • Octyldodecanol; (2RS)-2-octyldodecan-1-ol
    • Jarcol I 20
    • Fine Oxocol 2000
    • EINECS 226-242-9
    • BRN 1763479
    • AI3-19966
    • UNII-461N1O614Y
    • OHV 180
    • 2-octyl-dodecanol
    • Octyldodecanol CRS
    • Michel XO-150-20
    • EC 226-242-9
    • OCTYLDODECANOL [II]
    • OCTYLDODECANOL [MI]
    • SCHEMBL4873
    • 1-?Dodecanol, 2-?octyl-
    • 3-01-00-01844 (Beilstein Handbook Reference)
    • 2-Octyl-1-dodecanol, 97%
    • OCTYLDODECANOL [MART.]
    • SCHEMBL1616398
    • OCTYLDODECANOL [USP-RS]
    • OCTYLDODECANOL [WHO-DD]
    • CHEMBL1572050
    • SCHEMBL17102127
    • NSC2405
    • (+/-)-2-OCTYLDODECANOL
    • Tox21_112351
    • Tox21_302294
    • OCTYLDODECANOL [EP MONOGRAPH]
    • 2-OCTYLDODECANOL, (+/-)-
    • AKOS015912966
    • Tox21_112351_1
    • CS-W021736
    • DB14134
    • DS-6274
    • NCGC00166213-02
    • NCGC00255681-01
    • BP-30229
    • BP-31255
    • FO142351
    • SY052786
    • NS00002605
    • O0429
    • C20338
    • D77924
    • EN300-373383
    • SBI-0654217.0001
    • F791768
    • SR-01000944811
    • SR-01000944811-1
    • BRD-A51407134-001-01-9
    • Q27258886
    • Octyldodecanol, European Pharmacopoeia (EP) Reference Standard
    • Octyldodecanol, United States Pharmacopeia (USP) Reference Standard
    • Octyldodecanol, Pharmaceutical Secondary Standard; Certified Reference Material
    • 5333-42-6

  • Applications

    2-Octyldodecanol (CAS 5333-42-6) is a long-chain branched primary alcohol used widely as an emollient and non-volatile solvent in cosmetics and personal care, helping to soften the skin and act as a carrier for other ingredients. In perfumery and fragrance applications, it serves as a fixative and diluent to improve scent longevity and formulation stability. It also functions as a processing aid and lubricant in coatings, inks, and polymer formulations, aiding handling and dispersion. In industrial manufacturing, it can act as a plasticizer and processing lubricant for polymers, improving flexibility and processability. Additionally, as a synthetic intermediate, it is used to prepare esters and specialty fragrance ingredients.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 501.12
    methanol 218.17
    isopropanol 808.15
    water 0.01
    ethyl acetate 2071.25
    n-propanol 681.51
    acetone 1535.09
    n-butanol 958.04
    acetonitrile 354.3
    DMF 1091.19
    toluene 559.67
    isobutanol 706.73
    1,4-dioxane 1736.43
    methyl acetate 945.96
    THF 4729.44
    2-butanone 1594.5
    n-pentanol 493.8
    sec-butanol 838.0
    n-hexane 489.05
    ethylene glycol 11.24
    NMP 1643.1
    cyclohexane 2035.34
    DMSO 1476.59
    n-butyl acetate 3064.44
    n-octanol 510.43
    chloroform 2669.99
    n-propyl acetate 2188.33
    acetic acid 318.64
    dichloromethane 2630.77
    cyclohexanone 3947.27
    propylene glycol 56.24
    isopropyl acetate 2138.03
    DMAc 1258.79
    2-ethoxyethanol 673.94
    isopentanol 1124.9
    n-heptane 814.96
    ethyl formate 685.69
    1,2-dichloroethane 2321.21
    n-hexanol 678.86
    2-methoxyethanol 867.2
    isobutyl acetate 1479.27
    tetrachloromethane 998.97
    n-pentyl acetate 2451.68
    transcutol 3463.75
    n-heptanol 578.19
    ethylbenzene 416.15
    MIBK 1774.73
    2-propoxyethanol 1028.35
    tert-butanol 1469.09
    MTBE 2372.87
    2-butoxyethanol 1089.6
    propionic acid 444.34
    o-xylene 490.45
    formic acid 25.9
    diethyl ether 2224.41
    m-xylene 470.59
    p-xylene 610.83
    chlorobenzene 887.95
    dimethyl carbonate 267.52
    n-octane 233.72
    formamide 72.36
    cyclopentanone 3404.28
    2-pentanone 2128.45
    anisole 760.44
    cyclopentyl methyl ether 2837.09
    gamma-butyrolactone 2655.73
    1-methoxy-2-propanol 1086.39
    pyridine 1428.95
    3-pentanone 1504.22
    furfural 1372.73
    n-dodecane 77.75
    diethylene glycol 252.27
    diisopropyl ether 1137.08
    tert-amyl alcohol 1217.46
    acetylacetone 1842.4
    n-hexadecane 98.4
    acetophenone 855.33
    methyl propionate 1170.92
    isopentyl acetate 2852.37
    trichloroethylene 3054.31
    n-nonanol 514.64
    cyclohexanol 1579.5
    benzyl alcohol 379.97
    2-ethylhexanol 911.04
    isooctanol 692.12
    dipropyl ether 3124.33
    1,2-dichlorobenzene 1030.1
    ethyl lactate 496.21
    propylene carbonate 1580.75
    n-methylformamide 329.01
    2-pentanol 919.0
    n-pentane 383.07
    1-propoxy-2-propanol 1562.59
    1-methoxy-2-propyl acetate 1887.85
    2-(2-methoxypropoxy) propanol 677.18
    mesitylene 428.82
    ε-caprolactone 2883.68
    p-cymene 542.05
    epichlorohydrin 2743.91
    1,1,1-trichloroethane 2944.13
    2-aminoethanol 75.41
    morpholine-4-carbaldehyde 1464.58
    sulfolane 3447.75
    2,2,4-trimethylpentane 248.29
    2-methyltetrahydrofuran 3479.22
    n-hexyl acetate 1892.4
    isooctane 199.84
    2-(2-butoxyethoxy)ethanol 1071.63
    sec-butyl acetate 1854.32
    tert-butyl acetate 2752.52
    decalin 375.87
    glycerin 79.98
    diglyme 2769.62
    acrylic acid 205.04
    isopropyl myristate 737.88
    n-butyric acid 1624.95
    acetyl acetate 1016.58
    di(2-ethylhexyl) phthalate 343.66
    ethyl propionate 1792.36
    nitromethane 815.39
    1,2-diethoxyethane 2733.45
    benzonitrile 626.88
    trioctyl phosphate 357.85
    1-bromopropane 1955.79
    gamma-valerolactone 3422.62
    n-decanol 333.89
    triethyl phosphate 857.62
    4-methyl-2-pentanol 691.89
    propionitrile 593.06
    vinylene carbonate 963.04
    1,1,2-trichlorotrifluoroethane 1400.03
    DMS 724.16
    cumene 345.63
    2-octanol 565.67
    2-hexanone 1657.32
    octyl acetate 788.5
    limonene 1159.51
    1,2-dimethoxyethane 2271.18
    ethyl orthosilicate 959.35
    tributyl phosphate 493.7
    diacetone alcohol 1768.4
    N,N-dimethylaniline 566.36
    acrylonitrile 421.39
    aniline 541.44
    1,3-propanediol 310.4
    bromobenzene 1076.5
    dibromomethane 1979.46
    1,1,2,2-tetrachloroethane 3188.42
    2-methyl-cyclohexyl acetate 1477.29
    tetrabutyl urea 661.55
    diisobutyl methanol 853.47
    2-phenylethanol 469.56
    styrene 480.64
    dioctyl adipate 897.01
    dimethyl sulfate 549.59
    ethyl butyrate 2859.03
    methyl lactate 327.19
    butyl lactate 1137.78
    diethyl carbonate 1249.25
    propanediol butyl ether 601.66
    triethyl orthoformate 2038.42
    p-tert-butyltoluene 532.49
    methyl 4-tert-butylbenzoate 1011.88
    morpholine 2564.67
    tert-butylamine 1149.21
    n-dodecanol 237.11
    dimethoxymethane 1114.47
    ethylene carbonate 1163.7
    cyrene 563.69
    2-ethoxyethyl acetate 1934.02
    2-ethylhexyl acetate 2387.92
    1,2,4-trichlorobenzene 1080.21
    4-methylpyridine 1416.69
    dibutyl ether 2183.94
    2,6-dimethyl-4-heptanol 853.47
    DEF 2096.42
    dimethyl isosorbide 1519.19
    tetrachloroethylene 2012.91
    eugenol 621.92
    triacetin 1349.74
    span 80 732.52
    1,4-butanediol 87.27
    1,1-dichloroethane 2242.48
    2-methyl-1-pentanol 616.42
    methyl formate 229.89
    2-methyl-1-butanol 897.52
    n-decane 215.25
    butyronitrile 1067.16
    3,7-dimethyl-1-octanol 750.32
    1-chlorooctane 778.02
    1-chlorotetradecane 216.77
    n-nonane 238.28
    undecane 118.42
    tert-butylcyclohexane 309.93
    cyclooctane 472.13
    cyclopentanol 1291.75
    tetrahydropyran 4232.77
    tert-amyl methyl ether 1599.03
    2,5,8-trioxanonane 1297.76
    1-hexene 897.8
    2-isopropoxyethanol 705.03
    2,2,2-trifluoroethanol 129.68
    methyl butyrate 2366.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction