2-(Octadecyloxy)ethanol

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  • Identifiers

    CAS number
    2136-72-3

    Molecular formula
    C20H42O2

    SMILES
    CCCCCCCCCCCCCCCCCCOCCO

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Waxy 70.25%
    Fatty 54.21%
    Oily 47.1%
    Odorless 29.33%
    Fruity 28.92%
    Clean 27.08%
    Sweet 24.74%
    Fresh 23.24%
    Floral 20.72%
    Soapy 20.34%

     

    Flavor
    Waxy 67.3%
    Fatty 47.82%
    Mild 38.85%
    Soapy 37.63%
    Floral 36.09%
    Fat 36.0%
    Oily 34.91%
    Coconut 32.7%
    Flower 31.71%
    Wax 30.8%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.4

    pKa est.
    6.91 (neutral)

    Molecular weight
    314.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    404°C

    Flash point

    • 183.26 ˚C est.

  • Synonyms

    • 2-(Octadecyloxy)ethanol
    • 2136-72-3
    • 2-Octadecoxyethanol
    • Ethanol, 2-(octadecyloxy)-
    • Ethylene glycol monooctadecyl ether
    • 2-(octadecyloxy)ethan-1-ol
    • POE (10) stearyl alcohol ether
    • Steareth-21
    • Ethanol,2-(octadecyloxy)-
    • C20H42O2
    • MFCD00043351
    • 2-Octadecyloxyethanol
    • SP Brij? S2 MBAL
    • 2-(octadecyloxy) ethanol
    • 2-(octadecyloxy)-ethanol
    • DSSTox_CID_9299
    • DSSTox_RID_78754
    • DSSTox_GSID_29299
    • SCHEMBL490673
    • CHEMBL3181944
    • DTXSID60858842
    • EINECS 218-374-0
    • Tox21_202772
    • AKOS015839820
    • AS-2008
    • FO39233
    • NCGC00260319-01
    • CAS-9005-00-9
    • DB-066492
    • A4605
    • CS-0318307
    • NS00008395
    • NS00048617
    • D08975
    • F20467
    • F77844
    • G79814

  • Applications

    Chemical name: 2-(Octadecyloxy)ethanol; CAS number: 2136-72-3 is used as a nonionic surfactant and emulsifier in formulations. It acts as a co-solvent, a wetting agent, and helps disperse hydrophobic components in cosmetics and personal care products as well as in household cleaners. In industrial manufacturing, it functions as a processing aid and surfactant in coatings, inks, and adhesives, improving surface balance and dispersion of colors. It can be a intermediate to prepare other alkyl glyceryl ether derivatives and may serve as a co-solvent or plasticizer in certain polymer systems. Overall, typical applications span personal care, cleaning products, coatings/inks, and polymer processing, subject to formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 13.79
    methanol 13.8
    isopropanol 21.79
    water 0.02
    ethyl acetate 167.01
    n-propanol 26.91
    acetone 72.66
    n-butanol 41.68
    acetonitrile 28.03
    DMF 90.01
    toluene 53.31
    isobutanol 34.1
    1,4-dioxane 186.21
    methyl acetate 80.64
    THF 496.05
    2-butanone 111.9
    n-pentanol 35.01
    sec-butanol 39.86
    n-hexane 33.28
    ethylene glycol 1.84
    NMP 309.57
    cyclohexane 218.37
    DMSO 207.49
    n-butyl acetate 291.16
    n-octanol 70.28
    chloroform 459.21
    n-propyl acetate 257.88
    acetic acid 41.17
    dichloromethane 444.9
    cyclohexanone 472.94
    propylene glycol 6.07
    isopropyl acetate 193.47
    DMAc 186.6
    2-ethoxyethanol 84.32
    isopentanol 68.41
    n-heptane 84.84
    ethyl formate 64.6
    1,2-dichloroethane 320.76
    n-hexanol 47.71
    2-methoxyethanol 73.85
    isobutyl acetate 187.43
    tetrachloromethane 158.92
    n-pentyl acetate 399.02
    transcutol 585.4
    n-heptanol 64.54
    ethylbenzene 58.44
    MIBK 187.5
    2-propoxyethanol 101.79
    tert-butanol 71.73
    MTBE 141.01
    2-butoxyethanol 152.99
    propionic acid 47.39
    o-xylene 68.98
    formic acid 6.36
    diethyl ether 111.45
    m-xylene 56.33
    p-xylene 85.83
    chlorobenzene 108.86
    dimethyl carbonate 33.7
    n-octane 29.48
    formamide 13.55
    cyclopentanone 405.23
    2-pentanone 161.33
    anisole 115.87
    cyclopentyl methyl ether 320.3
    gamma-butyrolactone 371.64
    1-methoxy-2-propanol 93.25
    pyridine 150.76
    3-pentanone 139.5
    furfural 247.7
    n-dodecane 12.68
    diethylene glycol 33.61
    diisopropyl ether 89.24
    tert-amyl alcohol 88.39
    acetylacetone 200.52
    n-hexadecane 16.06
    acetophenone 164.44
    methyl propionate 101.91
    isopentyl acetate 292.41
    trichloroethylene 493.44
    n-nonanol 75.22
    cyclohexanol 143.92
    benzyl alcohol 58.51
    2-ethylhexanol 93.89
    isooctanol 84.26
    dipropyl ether 295.37
    1,2-dichlorobenzene 168.65
    ethyl lactate 83.47
    propylene carbonate 229.75
    n-methylformamide 29.74
    2-pentanol 49.23
    n-pentane 22.75
    1-propoxy-2-propanol 166.63
    1-methoxy-2-propyl acetate 235.29
    2-(2-methoxypropoxy) propanol 140.84
    mesitylene 59.91
    ε-caprolactone 407.01
    p-cymene 89.74
    epichlorohydrin 389.93
    1,1,1-trichloroethane 405.98
    2-aminoethanol 8.4
    morpholine-4-carbaldehyde 241.04
    sulfolane 706.92
    2,2,4-trimethylpentane 28.94
    2-methyltetrahydrofuran 373.43
    n-hexyl acetate 306.22
    isooctane 17.88
    2-(2-butoxyethoxy)ethanol 191.27
    sec-butyl acetate 217.32
    tert-butyl acetate 312.31
    decalin 60.07
    glycerin 13.72
    diglyme 515.95
    acrylic acid 28.59
    isopropyl myristate 117.75
    n-butyric acid 140.55
    acetyl acetate 121.68
    di(2-ethylhexyl) phthalate 70.98
    ethyl propionate 216.23
    nitromethane 101.38
    1,2-diethoxyethane 336.32
    benzonitrile 89.64
    trioctyl phosphate 64.45
    1-bromopropane 205.52
    gamma-valerolactone 480.24
    n-decanol 48.17
    triethyl phosphate 179.05
    4-methyl-2-pentanol 49.83
    propionitrile 42.2
    vinylene carbonate 155.99
    1,1,2-trichlorotrifluoroethane 262.9
    DMS 125.86
    cumene 55.7
    2-octanol 67.88
    2-hexanone 191.18
    octyl acetate 128.05
    limonene 176.22
    1,2-dimethoxyethane 285.68
    ethyl orthosilicate 190.38
    tributyl phosphate 90.87
    diacetone alcohol 218.31
    N,N-dimethylaniline 98.82
    acrylonitrile 38.11
    aniline 54.47
    1,3-propanediol 23.15
    bromobenzene 141.83
    dibromomethane 315.1
    1,1,2,2-tetrachloroethane 565.81
    2-methyl-cyclohexyl acetate 263.04
    tetrabutyl urea 134.94
    diisobutyl methanol 103.89
    2-phenylethanol 66.81
    styrene 62.22
    dioctyl adipate 180.88
    dimethyl sulfate 96.67
    ethyl butyrate 354.05
    methyl lactate 45.06
    butyl lactate 191.04
    diethyl carbonate 174.96
    propanediol butyl ether 97.26
    triethyl orthoformate 314.41
    p-tert-butyltoluene 84.05
    methyl 4-tert-butylbenzoate 220.81
    morpholine 238.76
    tert-butylamine 59.24
    n-dodecanol 34.91
    dimethoxymethane 91.64
    ethylene carbonate 166.61
    cyrene 152.97
    2-ethoxyethyl acetate 311.75
    2-ethylhexyl acetate 274.28
    1,2,4-trichlorobenzene 195.47
    4-methylpyridine 138.53
    dibutyl ether 272.88
    2,6-dimethyl-4-heptanol 103.89
    DEF 209.88
    dimethyl isosorbide 358.02
    tetrachloroethylene 364.55
    eugenol 144.96
    triacetin 303.73
    span 80 143.93
    1,4-butanediol 10.37
    1,1-dichloroethane 234.08
    2-methyl-1-pentanol 56.7
    methyl formate 24.92
    2-methyl-1-butanol 57.9
    n-decane 33.27
    butyronitrile 64.88
    3,7-dimethyl-1-octanol 97.05
    1-chlorooctane 125.04
    1-chlorotetradecane 36.76
    n-nonane 35.0
    undecane 18.7
    tert-butylcyclohexane 43.7
    cyclooctane 60.51
    cyclopentanol 121.27
    tetrahydropyran 363.43
    tert-amyl methyl ether 151.35
    2,5,8-trioxanonane 280.55
    1-hexene 58.04
    2-isopropoxyethanol 88.69
    2,2,2-trifluoroethanol 25.94
    methyl butyrate 288.4

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction