2-Naphthoxyacetic acid

Overview IFRA Request a quote

  • Identifiers

    CAS number
    120-23-0

    Molecular formula
    C12H10O3

    SMILES
    C1=CC=C2C=C(C=CC2=C1)OCC(=O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Honey 61.21%
    Floral 55.03%
    Sweet 51.92%
    Balsamic 42.38%
    Powdery 38.74%
    Phenolic 34.64%
    Rose 34.29%
    Fatty 33.94%
    Animal 30.35%
    Aromatic 25.98%

     

    Flavor
    Sweet 85.02%
    Balsam 53.71%
    Honey 43.42%
    Floral 42.31%
    Balsamic 39.7%
    Powdery 34.45%
    Creamy 32.54%
    Faint 32.22%
    Sour 30.8%
    Mild 30.1%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    7.31 (neutral)

    Molecular weight
    202.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    384°C

    Melting point expt.

    • 156 °C

    Flash point

    • 199.56 ˚C est.

  • Synonyms

    • 2-Naphthoxyacetic acid
    • 120-23-0
    • (2-Naphthyloxy)acetic acid
    • 2-Naphthyloxyacetic acid
    • Betoxon
    • 2-Noxa
    • NOXA
    • Betapal
    • BETA-NAPHTHOXYACETIC ACID
    • O-(2-Naphthyl)glycolic acid
    • Betokson
    • beta-Naphthyloxyacetic acid
    • (beta-Naphthalenyloxy)acetic acid
    • DTXSID2042195
    • 717GVR334R
    • NSC-2070
    • DTXCID0022195
    • CHEBI:50397
    • RefChem:910128
    • 204-380-0
    • Bnoa
    • 2-(Naphthalen-2-yloxy)acetic acid
    • 2-(2-naphthyloxy)acetic acid
    • Acetic acid, (2-naphthalenyloxy)-
    • Gerlach 1396
    • (2-Naphthalenyloxy)acetic acid
    • 2-naphthalen-2-yloxyacetic acid
    • Acetic acid, 2-(2-naphthalenyloxy)-
    • (2-Naphthloxy)acetic acid
    • (naphthalen-2-yloxy)acetic acid
    • Acetic acid, (2-naphthyloxy)-
    • b-Naphthoxyacetic acid
    • (2-Naphthoxy)acetic acid
    • 2-Naphthalenoxyacetic acid
    • MFCD00004066
    • NSC 2070
    • .beta.-Naphthoxyacetic acid
    • 2-naphthoxy acetic acid
    • (.beta.-Naphthalenyloxy)acetic acid
    • 2-(2-Naphthoxy)acetic acid
    • .beta.-Naphthyloxyacetic acid
    • CCRIS 3156
    • Acide naphtyloxyacetique
    • 2-Napthyloxyacetic acid
    • Acide naphthyloxyacetique [French]
    • Acide naphthyloxyacetique
    • EINECS 204-380-0
    • Acide naphtyloxyacetique [ISO-French]
    • (2-Naphthyloxy)acetic acid [BSI:ISO]
    • BRN 1074148
    • Betokson super
    • UNII-717GVR334R
    • AI3-14654
    • A1ISN
    • (b-Naphthyloxy)acetic acid
    • BDBM50
    • (2-naphthoxy)ethanoic acid
    • cid_8422
    • Oprea1_727299
    • SCHEMBL25640
    • (2-naphthyloxy)-Acetic acid
    • CBDivE_003164
    • (beta-Naphthyloxy)acetic acid
    • 2-Naphthalenyloxyethanoic acid
    • (b-Naphthalenyloxy)acetic acid
    • 2-Naphthoxyacetic acid, 98%
    • orb1692346
    • orb3026050
    • SCHEMBL3483085
    • SCHEMBL3483381
    • SCHEMBL6563888
    • Glycollic acid 2-naphthyl ether
    • BNOA, beta-naphthoxyacetic acid
    • CHEMBL1732186
    • SCHEMBL29367022
    • (2-naphthalenyloxy)-Acetic acid
    • RZCJYMOBWVJQGV-UHFFFAOYSA-
    • NSC2070
    • (naphthalen-2-yloxy)-acetic acid
    • 2-(2-naphthalenyloxy)acetic acid
    • 2-naphthalen-2-yloxyethanoic acid
    • HMS3753E11
    • ACETIC ACID, 2-NAPHTHOXY-
    • [(Naphthalen-2-yl)oxy]acetic acid
    • 2-(2-Naphthalenyloxy)-Acetic acid
    • MSK24062
    • 2-NAPHTHOXYACETIC ACID [MI]
    • Tox21_301390
    • NOXA (NAPHTHYLOXYACETIC ACID)
    • SBB003523
    • STK117074
    • AKOS000101579
    • CS-W015512
    • EBC-612498
    • FN34496
    • HY-W014796
    • KS-5264
    • (.BETA.-NAPHTHYLOXY)ACETIC ACID
    • NCGC00166229-01
    • NCGC00255805-01
    • (2-NAPHTHYLOXY)ACETIC ACID [ISO]
    • CAS-120-23-0
    • PD158315
    • SY015707
    • N0045
    • NS00000707
    • ST45061288
    • (2-Naphthyloxy)acetic acid, 8CI, BSI, ISO
    • EN300-18402
    • C18750
    • H11815
    • MLS-0412048.0001
    • AC-907/25014305
    • F791382
    • Q27122052
    • Z57246951
    • 2-Naphthoxyacetic acid, Vetec(TM) reagent grade, 98%
    • F0307-0743
    • 2-Naphthoxyacetic acid, PESTANAL(R), analytical standard
    • 2-Naphthoxyacetic acid, BioReagent, plant cell culture tested, crystalline
    • InChI=1/C12H10O3/c13-12(14)8-15-11-6-5-9-3-1-2-4-10(9)7-11/h1-7H,8H2,(H,13,14)
    • 120-23-0

  • Applications

    2-Naphthoxyacetic acid is primarily used as an intermediate in organic synthesis, notably as a building block for phenoxyacetic acid derivatives used in agrochemicals, including herbicides. It is also commonly employed as a building block in pharmaceutical synthesis and in fragrance and cosmetics formulation. Additionally, the compound serves as a precursor for aryl ether intermediates in dye, pigment, coatings, and ink chemistries, and as a building block in polymer and plastic material development. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 104.7
    methanol 164.98
    isopropanol 46.65
    water 0.33
    ethyl acetate 63.7
    n-propanol 68.75
    acetone 179.43
    n-butanol 40.25
    acetonitrile 47.22
    DMF 176.56
    toluene 4.22
    isobutanol 29.77
    1,4-dioxane 155.43
    methyl acetate 89.6
    THF 248.94
    2-butanone 93.71
    n-pentanol 48.8
    sec-butanol 37.81
    n-hexane 0.1
    ethylene glycol 75.8
    NMP 44.6
    cyclohexane 0.09
    DMSO 422.78
    n-butyl acetate 32.43
    n-octanol 9.68
    chloroform 5.98
    n-propyl acetate 49.37
    acetic acid 71.16
    dichloromethane 11.26
    cyclohexanone 40.24
    propylene glycol 49.96
    isopropyl acetate 34.03
    DMAc 208.64
    2-ethoxyethanol 228.23
    isopentanol 37.37
    n-heptane 0.41
    ethyl formate 26.78
    1,2-dichloroethane 28.01
    n-hexanol 30.39
    2-methoxyethanol 256.24
    isobutyl acetate 23.71
    tetrachloromethane 0.92
    n-pentyl acetate 13.54
    transcutol 403.18
    n-heptanol 12.18
    ethylbenzene 5.84
    MIBK 33.45
    2-propoxyethanol 104.78
    tert-butanol 81.48
    MTBE 38.32
    2-butoxyethanol 44.86
    propionic acid 42.01
    o-xylene 4.99
    formic acid 71.07
    diethyl ether 40.76
    m-xylene 4.71
    p-xylene 6.28
    chlorobenzene 6.45
    dimethyl carbonate 37.62
    n-octane 0.33
    formamide 202.46
    cyclopentanone 76.36
    2-pentanone 52.74
    anisole 40.57
    cyclopentyl methyl ether 33.33
    gamma-butyrolactone 95.23
    1-methoxy-2-propanol 133.21
    pyridine 41.26
    3-pentanone 32.89
    furfural 68.0
    n-dodecane 0.55
    diethylene glycol 132.72
    diisopropyl ether 8.95
    tert-amyl alcohol 55.83
    acetylacetone 79.04
    n-hexadecane 0.61
    acetophenone 33.94
    methyl propionate 54.45
    isopentyl acetate 30.58
    trichloroethylene 40.64
    n-nonanol 10.56
    cyclohexanol 15.51
    benzyl alcohol 34.94
    2-ethylhexanol 15.74
    isooctanol 11.26
    dipropyl ether 20.88
    1,2-dichlorobenzene 8.39
    ethyl lactate 30.57
    propylene carbonate 32.73
    n-methylformamide 104.65
    2-pentanol 22.04
    n-pentane 0.08
    1-propoxy-2-propanol 59.23
    1-methoxy-2-propyl acetate 55.67
    2-(2-methoxypropoxy) propanol 62.35
    mesitylene 3.39
    ε-caprolactone 41.25
    p-cymene 6.44
    epichlorohydrin 149.62
    1,1,1-trichloroethane 8.0
    2-aminoethanol 104.68
    morpholine-4-carbaldehyde 118.06
    sulfolane 101.76
    2,2,4-trimethylpentane 0.49
    2-methyltetrahydrofuran 74.49
    n-hexyl acetate 19.71
    isooctane 0.41
    2-(2-butoxyethoxy)ethanol 86.71
    sec-butyl acetate 30.87
    tert-butyl acetate 46.62
    decalin 0.62
    glycerin 91.61
    diglyme 174.54
    acrylic acid 39.72
    isopropyl myristate 11.45
    n-butyric acid 35.99
    acetyl acetate 28.38
    di(2-ethylhexyl) phthalate 12.95
    ethyl propionate 41.55
    nitromethane 174.08
    1,2-diethoxyethane 77.78
    benzonitrile 17.9
    trioctyl phosphate 8.73
    1-bromopropane 5.46
    gamma-valerolactone 105.51
    n-decanol 8.75
    triethyl phosphate 18.8
    4-methyl-2-pentanol 16.21
    propionitrile 32.65
    vinylene carbonate 26.51
    1,1,2-trichlorotrifluoroethane 78.94
    DMS 30.69
    cumene 5.53
    2-octanol 7.02
    2-hexanone 44.45
    octyl acetate 13.64
    limonene 7.43
    1,2-dimethoxyethane 220.27
    ethyl orthosilicate 18.26
    tributyl phosphate 12.02
    diacetone alcohol 81.22
    N,N-dimethylaniline 25.0
    acrylonitrile 46.17
    aniline 16.75
    1,3-propanediol 104.93
    bromobenzene 4.53
    dibromomethane 4.26
    1,1,2,2-tetrachloroethane 30.22
    2-methyl-cyclohexyl acetate 23.59
    tetrabutyl urea 18.59
    diisobutyl methanol 11.66
    2-phenylethanol 28.54
    styrene 6.65
    dioctyl adipate 20.61
    dimethyl sulfate 59.66
    ethyl butyrate 29.41
    methyl lactate 37.56
    butyl lactate 18.86
    diethyl carbonate 24.22
    propanediol butyl ether 41.06
    triethyl orthoformate 23.42
    p-tert-butyltoluene 6.23
    methyl 4-tert-butylbenzoate 30.31
    morpholine 172.83
    tert-butylamine 24.37
    n-dodecanol 7.29
    dimethoxymethane 168.84
    ethylene carbonate 22.77
    cyrene 47.13
    2-ethoxyethyl acetate 37.26
    2-ethylhexyl acetate 21.16
    1,2,4-trichlorobenzene 12.18
    4-methylpyridine 26.11
    dibutyl ether 16.88
    2,6-dimethyl-4-heptanol 11.66
    DEF 52.91
    dimethyl isosorbide 88.48
    tetrachloroethylene 16.97
    eugenol 35.97
    triacetin 33.57
    span 80 33.07
    1,4-butanediol 52.64
    1,1-dichloroethane 8.39
    2-methyl-1-pentanol 37.11
    methyl formate 67.94
    2-methyl-1-butanol 33.26
    n-decane 0.72
    butyronitrile 23.84
    3,7-dimethyl-1-octanol 13.48
    1-chlorooctane 4.18
    1-chlorotetradecane 2.32
    n-nonane 0.53
    undecane 0.63
    tert-butylcyclohexane 0.82
    cyclooctane 0.09
    cyclopentanol 20.49
    tetrahydropyran 51.27
    tert-amyl methyl ether 32.25
    2,5,8-trioxanonane 123.28
    1-hexene 1.77
    2-isopropoxyethanol 116.03
    2,2,2-trifluoroethanol 26.14
    methyl butyrate 46.45

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction