2-Naphthaleneethanol, 1,2,3,4,4a,5,6,8a-octahydro-4a,8-dimethyl-beta-methylene-, (2R,4aR,8aR)-

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  • Identifiers

    CAS number
    65018-15-7

    Molecular formula
    C15H24O

    SMILES
    CC1=CCC[C@]2([C@H]1C[C@@H](CC2)C(=C)CO)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 75.83%
    Sweet 62.58%
    Amber 40.41%
    Balsamic 39.44%
    Floral 37.92%
    Dry 37.22%
    Sandalwood 36.75%
    Fruity 36.6%
    Cedar 33.66%
    Herbal 33.51%

     

    Flavor
    Woody 48.75%
    Sweet 48.04%
    Herbal 39.9%
    Spicy 36.81%
    Fruity 34.16%
    Spice 31.53%
    Balsam 30.13%
    Fresh 28.52%
    Herb 28.21%
    Wood 27.84%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.0

    pKa est.
    9.54 (weak base)

    Molecular weight
    220.35 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    328°C

    Flash point

    • 136.1 ˚C est.

  • Synonyms

    • RefChem:1063889
    • 2-((2R,4aR,8aR)-4a,8-dimethyl-2,3,4,5,6,8a-hexahydro-1H-naphthalen-2-yl)prop-2-en-1-ol
    • 2-Naphthaleneethanol, 1,2,3,4,4a,5,6,8a-octahydro-4a,8-dimethyl-beta-methylene-, (2R,4aR,8aR)-
    • alpha-Costol
    • .alpha.-Costol
    • 65018-15-7
    • (-)-.alpha.-Costol
    • MTJCJJFCDOSALI-QLFBSQMISA-N
    • 2-((2R,4aR,8aR)-4a,8-Dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl)prop-2-en-1-ol
    • 2-Naphthaleneethanol, 1,2,3,4,4a,5,6,8a-octahydro-4a,8-dimethyl-.beta.-methylene-, (2R,4aR,8aR)-
    • 2-Naphthaleneethanol, 1,2,3,4,4a,5,6,8a-octahydro-4a,8-dimethyl-.beta.-methylene-, [2R-(2.alpha.,4a.alpha.,8a.beta.)]-
    • 65018-15-7

  • Applications

    2-Naphthaleneethanol, 1,2,3,4,4a,5,6,8a-octahydro-4a,8-dimethyl-beta-methylene-, (2R,4aR,8aR)- (CAS 65018-15-7) is primarily used as a fragrance ingredient and odorant in perfumery and cosmetics, and may appear as a fragrance component in household products. In industrial manufacturing, it is commonly evaluated as a chiral intermediate and building block for the synthesis of specialty chemicals. In pharmaceutical research, it may serve as a stereochemically defined intermediate where a rigid bicyclic framework is advantageous. Depending on regulatory and formulation constraints, it is considered for applications requiring a naphthyl bicyclic motif in aroma-related formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2909.19
    methanol 2393.59
    isopropanol 2853.03
    water 0.54
    ethyl acetate 3475.29
    n-propanol 3201.18
    acetone 2284.89
    n-butanol 3041.13
    acetonitrile 1764.11
    DMF 2133.18
    toluene 2215.23
    isobutanol 1669.89
    1,4-dioxane 5104.94
    methyl acetate 1887.07
    THF 6266.49
    2-butanone 2451.92
    n-pentanol 745.78
    sec-butanol 1487.77
    n-hexane 68.01
    ethylene glycol 118.34
    NMP 508.75
    cyclohexane 280.72
    DMSO 1001.37
    n-butyl acetate 1683.42
    n-octanol 237.43
    chloroform 3038.38
    n-propyl acetate 974.72
    acetic acid 604.31
    dichloromethane 2327.98
    cyclohexanone 1919.91
    propylene glycol 268.41
    isopropyl acetate 1955.27
    DMAc 873.99
    2-ethoxyethanol 1249.61
    isopentanol 1947.72
    n-heptane 60.13
    ethyl formate 1183.71
    1,2-dichloroethane 1782.22
    n-hexanol 1292.68
    2-methoxyethanol 3582.93
    isobutyl acetate 524.6
    tetrachloromethane 532.55
    n-pentyl acetate 605.82
    transcutol 5820.63
    n-heptanol 347.13
    ethylbenzene 384.86
    MIBK 1150.34
    2-propoxyethanol 2387.69
    tert-butanol 2713.84
    MTBE 3780.26
    2-butoxyethanol 844.12
    propionic acid 743.31
    o-xylene 629.98
    formic acid 203.01
    diethyl ether 5191.96
    m-xylene 1082.32
    p-xylene 375.96
    chlorobenzene 1095.18
    dimethyl carbonate 567.28
    n-octane 15.2
    formamide 586.74
    cyclopentanone 2000.78
    2-pentanone 2435.11
    anisole 930.8
    cyclopentyl methyl ether 2307.5
    gamma-butyrolactone 1793.97
    1-methoxy-2-propanol 2738.88
    pyridine 3012.91
    3-pentanone 1415.21
    furfural 1270.45
    n-dodecane 8.44
    diethylene glycol 961.0
    diisopropyl ether 884.45
    tert-amyl alcohol 1220.16
    acetylacetone 1564.41
    n-hexadecane 10.53
    acetophenone 490.53
    methyl propionate 1907.86
    isopentyl acetate 1347.77
    trichloroethylene 2723.86
    n-nonanol 204.05
    cyclohexanol 1275.12
    benzyl alcohol 564.05
    2-ethylhexanol 502.09
    isooctanol 274.61
    dipropyl ether 1207.39
    1,2-dichlorobenzene 712.44
    ethyl lactate 262.27
    propylene carbonate 791.83
    n-methylformamide 1676.78
    2-pentanol 1527.87
    n-pentane 169.96
    1-propoxy-2-propanol 1671.76
    1-methoxy-2-propyl acetate 1824.64
    2-(2-methoxypropoxy) propanol 584.93
    mesitylene 546.85
    ε-caprolactone 1461.5
    p-cymene 225.47
    epichlorohydrin 2843.01
    1,1,1-trichloroethane 1513.82
    2-aminoethanol 581.14
    morpholine-4-carbaldehyde 1444.59
    sulfolane 840.91
    2,2,4-trimethylpentane 55.55
    2-methyltetrahydrofuran 3123.63
    n-hexyl acetate 664.34
    isooctane 80.71
    2-(2-butoxyethoxy)ethanol 1139.53
    sec-butyl acetate 673.05
    tert-butyl acetate 1711.3
    decalin 57.35
    glycerin 304.68
    diglyme 2422.82
    acrylic acid 396.57
    isopropyl myristate 181.5
    n-butyric acid 2034.31
    acetyl acetate 928.4
    di(2-ethylhexyl) phthalate 175.74
    ethyl propionate 855.05
    nitromethane 1366.32
    1,2-diethoxyethane 2656.0
    benzonitrile 815.01
    trioctyl phosphate 112.62
    1-bromopropane 1322.19
    gamma-valerolactone 2432.58
    n-decanol 134.97
    triethyl phosphate 241.19
    4-methyl-2-pentanol 722.96
    propionitrile 2215.93
    vinylene carbonate 837.1
    1,1,2-trichlorotrifluoroethane 894.32
    DMS 485.36
    cumene 199.38
    2-octanol 179.69
    2-hexanone 761.31
    octyl acetate 221.92
    limonene 310.33
    1,2-dimethoxyethane 2396.9
    ethyl orthosilicate 293.66
    tributyl phosphate 160.07
    diacetone alcohol 1203.8
    N,N-dimethylaniline 418.0
    acrylonitrile 1721.5
    aniline 1886.03
    1,3-propanediol 1581.39
    bromobenzene 1131.22
    dibromomethane 1648.34
    1,1,2,2-tetrachloroethane 1882.43
    2-methyl-cyclohexyl acetate 392.11
    tetrabutyl urea 173.5
    diisobutyl methanol 341.93
    2-phenylethanol 752.63
    styrene 505.98
    dioctyl adipate 243.26
    dimethyl sulfate 409.34
    ethyl butyrate 944.6
    methyl lactate 434.93
    butyl lactate 403.56
    diethyl carbonate 510.59
    propanediol butyl ether 540.11
    triethyl orthoformate 678.08
    p-tert-butyltoluene 261.62
    methyl 4-tert-butylbenzoate 423.56
    morpholine 6105.99
    tert-butylamine 1861.51
    n-dodecanol 88.77
    dimethoxymethane 3322.94
    ethylene carbonate 849.19
    cyrene 308.12
    2-ethoxyethyl acetate 1120.75
    2-ethylhexyl acetate 892.04
    1,2,4-trichlorobenzene 754.7
    4-methylpyridine 2679.71
    dibutyl ether 527.15
    2,6-dimethyl-4-heptanol 341.93
    DEF 1630.22
    dimethyl isosorbide 949.96
    tetrachloroethylene 1197.35
    eugenol 386.03
    triacetin 473.19
    span 80 407.64
    1,4-butanediol 224.47
    1,1-dichloroethane 2090.44
    2-methyl-1-pentanol 521.97
    methyl formate 884.1
    2-methyl-1-butanol 1415.2
    n-decane 19.87
    butyronitrile 2659.79
    3,7-dimethyl-1-octanol 328.5
    1-chlorooctane 132.28
    1-chlorotetradecane 34.98
    n-nonane 18.59
    undecane 12.23
    tert-butylcyclohexane 58.83
    cyclooctane 81.39
    cyclopentanol 924.11
    tetrahydropyran 5728.76
    tert-amyl methyl ether 1358.41
    2,5,8-trioxanonane 1139.76
    1-hexene 324.42
    2-isopropoxyethanol 725.13
    2,2,2-trifluoroethanol 174.91
    methyl butyrate 951.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction