2-Methylquinolin-4-ol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    607-67-0

    Molecular formula
    C10H9NO

    SMILES
    CC1=CC(=O)C2=CC=CC=C2N1

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Animal 41.41%
    Phenolic 39.43%
    Burnt 37.61%
    Musty 31.27%
    Fruity 29.31%
    Bitter 29.09%
    Nutty 27.48%
    Roasted 27.36%
    Tobacco 25.03%
    Sweet 24.41%

     

    Flavor
    Bitter 80.86%
    Very strong 22.8%
    Indole 22.32%
    Nitrile 21.05%
    Moth ball 20.94%
    Naphthelene 20.68%
    Almond shell 20.66%
    Curry 20.4%
    Flat 20.2%
    Bread crust 20.15%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    6.45 (neutral)

    Molecular weight
    159.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    367°C

    Flash point

    • 152.62 ˚C est.

  • Synonyms

    • 4-Hydroxy-2-methylquinoline
    • 2-Methylquinolin-4-ol
    • 607-67-0
    • EINECS 210-140-6
    • DTXSID40209515
    • NSC 21483
    • RefChem:476257
    • DTXCID90132006
    • 210-140-6
    • 2-methylquinolin-4(1H)-one
    • 2-Methyl-4-quinolinol
    • 2-methyl-1H-quinolin-4-one
    • 4-Quinolinol, 2-methyl-
    • 4-Hydroxyquinaldine
    • 2-Methyl-4-hydroxyquinoline
    • MFCD00006758
    • 4(1H)-Quinolinone, 2-methyl-
    • 2-METHYLQUINOLIN-4-ONE
    • 2-Methyl-quinolin-4-ol
    • 1H-4-Oxoquinaldine
    • MFCD00518775
    • 2-methyl-quinolin-4(1H)-one
    • NSC-21483
    • NSC21483
    • VFH
    • 2-Methyl-4-quinolinone
    • Maybridge1_000216
    • DMH3M2MT6S
    • Oprea1_457343
    • Oprea1_710493
    • MLS000084685
    • SCHEMBL266459
    • SCHEMBL527043
    • orb3030029
    • SCHEMBL3458273
    • SCHEMBL6447066
    • SCHEMBL9163258
    • CHEMBL1256109
    • SCHEMBL30199873
    • HMS542B18
    • NWINIEGDLHHNLH-UHFFFAOYSA-
    • WLZ3963
    • CHEBI:194391
    • HMS2364A23
    • KUC100216N
    • ALBB-019943
    • BB_SC-06490
    • c1269
    • CCG-44041
    • EBC-76056
    • SBB003979
    • STK024344
    • STK054930
    • ZB0110
    • AKOS000265038
    • AKOS003238098
    • 4-Hydroxy-2-methylquinoline, 98.5%
    • EBC-153107
    • SB67513
    • SB67949
    • SMR000019032
    • SY048580
    • TS-02117
    • DB-053699
    • DB-081638
    • CS-0019244
    • CS-0159505
    • M2620
    • NS00034449
    • ST45025443
    • C21873
    • D82318
    • EN300-129304
    • F16203
    • AB00404214-09
    • 660M242
    • AH-034/32851007
    • SR-01000620630-2
    • F0451-0420
    • Z445211720
    • InChI=1/C10H9NO/c1-7-6-10(12)8-4-2-3-5-9(8)11-7/h2-6H,1H3,(H,11,12)
    • 607-67-0

  • Applications

    2-Methylquinolin-4-ol (CAS 607-67-0) is primarily used as an intermediate in the synthesis of heterocyclic compounds for pharmaceutical and agricultural chemical research, serving as a building block for quinoline derivatives studied for drug development and crop protection. It is also employed as a precursor for color and pigment compounds used in coatings and printing materials, and can function as a ligand or building block in coordination chemistry and catalysis. Given its quinoline framework, it is explored as a component for organic electronic materials and functional polymers, including potential applications in OLEDs and related organic semiconductors. Actual use is subject to local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 54.97
    methanol 51.66
    isopropanol 41.16
    water 1.54
    ethyl acetate 45.24
    n-propanol 48.82
    acetone 97.52
    n-butanol 44.09
    acetonitrile 53.06
    DMF 319.56
    toluene 12.55
    isobutanol 39.12
    1,4-dioxane 100.04
    methyl acetate 53.93
    THF 161.63
    2-butanone 68.03
    n-pentanol 43.56
    sec-butanol 33.96
    n-hexane 3.24
    ethylene glycol 21.16
    NMP 152.31
    cyclohexane 2.24
    DMSO 278.28
    n-butyl acetate 50.48
    n-octanol 34.18
    chloroform 73.66
    n-propyl acetate 48.0
    acetic acid 57.75
    dichloromethane 94.48
    cyclohexanone 106.16
    propylene glycol 18.86
    isopropyl acetate 28.07
    DMAc 144.4
    2-ethoxyethanol 62.9
    isopentanol 38.44
    n-heptane 5.69
    ethyl formate 53.15
    1,2-dichloroethane 63.26
    n-hexanol 59.34
    2-methoxyethanol 95.56
    isobutyl acetate 32.7
    tetrachloromethane 9.03
    n-pentyl acetate 37.29
    transcutol 119.07
    n-heptanol 33.96
    ethylbenzene 15.36
    MIBK 42.16
    2-propoxyethanol 91.95
    tert-butanol 44.47
    MTBE 24.07
    2-butoxyethanol 57.25
    propionic acid 48.68
    o-xylene 14.1
    formic acid 22.08
    diethyl ether 27.7
    m-xylene 16.59
    p-xylene 23.3
    chlorobenzene 26.73
    dimethyl carbonate 32.78
    n-octane 2.96
    formamide 43.68
    cyclopentanone 149.54
    2-pentanone 62.6
    anisole 37.28
    cyclopentyl methyl ether 57.11
    gamma-butyrolactone 162.25
    1-methoxy-2-propanol 72.44
    pyridine 62.61
    3-pentanone 46.53
    furfural 111.87
    n-dodecane 3.23
    diethylene glycol 73.38
    diisopropyl ether 9.42
    tert-amyl alcohol 33.09
    acetylacetone 70.58
    n-hexadecane 3.61
    acetophenone 47.82
    methyl propionate 55.27
    isopentyl acetate 41.68
    trichloroethylene 100.58
    n-nonanol 31.08
    cyclohexanol 35.47
    benzyl alcohol 39.42
    2-ethylhexanol 36.2
    isooctanol 28.79
    dipropyl ether 35.89
    1,2-dichlorobenzene 30.13
    ethyl lactate 36.31
    propylene carbonate 78.74
    n-methylformamide 105.56
    2-pentanol 27.09
    n-pentane 2.36
    1-propoxy-2-propanol 64.67
    1-methoxy-2-propyl acetate 53.43
    2-(2-methoxypropoxy) propanol 54.1
    mesitylene 10.98
    ε-caprolactone 81.78
    p-cymene 16.96
    epichlorohydrin 141.84
    1,1,1-trichloroethane 37.52
    2-aminoethanol 34.28
    morpholine-4-carbaldehyde 144.67
    sulfolane 171.89
    2,2,4-trimethylpentane 1.93
    2-methyltetrahydrofuran 77.33
    n-hexyl acetate 50.56
    isooctane 1.92
    2-(2-butoxyethoxy)ethanol 72.82
    sec-butyl acetate 28.04
    tert-butyl acetate 30.71
    decalin 3.31
    glycerin 34.02
    diglyme 125.65
    acrylic acid 44.29
    isopropyl myristate 23.27
    n-butyric acid 54.68
    acetyl acetate 29.4
    di(2-ethylhexyl) phthalate 28.37
    ethyl propionate 43.3
    nitromethane 107.5
    1,2-diethoxyethane 51.42
    benzonitrile 46.08
    trioctyl phosphate 23.74
    1-bromopropane 31.16
    gamma-valerolactone 153.11
    n-decanol 25.77
    triethyl phosphate 26.52
    4-methyl-2-pentanol 20.94
    propionitrile 49.05
    vinylene carbonate 72.28
    1,1,2-trichlorotrifluoroethane 67.24
    DMS 43.74
    cumene 15.92
    2-octanol 25.72
    2-hexanone 55.32
    octyl acetate 32.13
    limonene 21.44
    1,2-dimethoxyethane 127.58
    ethyl orthosilicate 23.21
    tributyl phosphate 26.23
    diacetone alcohol 53.03
    N,N-dimethylaniline 34.26
    acrylonitrile 66.26
    aniline 25.27
    1,3-propanediol 47.81
    bromobenzene 21.92
    dibromomethane 54.21
    1,1,2,2-tetrachloroethane 73.4
    2-methyl-cyclohexyl acetate 38.52
    tetrabutyl urea 39.96
    diisobutyl methanol 20.93
    2-phenylethanol 43.79
    styrene 15.02
    dioctyl adipate 34.03
    dimethyl sulfate 58.37
    ethyl butyrate 42.28
    methyl lactate 37.05
    butyl lactate 38.53
    diethyl carbonate 30.69
    propanediol butyl ether 49.47
    triethyl orthoformate 28.62
    p-tert-butyltoluene 14.62
    methyl 4-tert-butylbenzoate 49.58
    morpholine 99.36
    tert-butylamine 23.24
    n-dodecanol 21.21
    dimethoxymethane 109.55
    ethylene carbonate 61.45
    cyrene 62.07
    2-ethoxyethyl acetate 47.11
    2-ethylhexyl acetate 34.15
    1,2,4-trichlorobenzene 36.51
    4-methylpyridine 58.46
    dibutyl ether 31.49
    2,6-dimethyl-4-heptanol 20.93
    DEF 81.14
    dimethyl isosorbide 83.4
    tetrachloroethylene 44.73
    eugenol 57.12
    triacetin 46.12
    span 80 46.16
    1,4-butanediol 31.09
    1,1-dichloroethane 49.31
    2-methyl-1-pentanol 38.99
    methyl formate 85.6
    2-methyl-1-butanol 35.26
    n-decane 4.58
    butyronitrile 52.86
    3,7-dimethyl-1-octanol 30.32
    1-chlorooctane 19.83
    1-chlorotetradecane 8.96
    n-nonane 4.21
    undecane 3.82
    tert-butylcyclohexane 3.77
    cyclooctane 1.15
    cyclopentanol 48.57
    tetrahydropyran 62.36
    tert-amyl methyl ether 21.96
    2,5,8-trioxanonane 89.93
    1-hexene 15.86
    2-isopropoxyethanol 49.69
    2,2,2-trifluoroethanol 29.34
    methyl butyrate 63.59

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction