2-Methylbutylamine, (S)-

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  • Identifiers

    CAS number
    34985-37-0

    Molecular formula
    C5H13N

    SMILES
    CC[C@H](C)CN

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Cheesy 83.34%
    Fishy 78.69%
    Ripe 58.92%
    Sweaty 26.19%
    Fermented 26.18%
    Pungent 24.49%
    Oily 24.37%
    Fresh 23.52%
    Meaty 23.4%
    Animal 22.86%

     

    Flavor
    Fishy 43.71%
    Ammoniacal 37.18%
    Ammonia 29.86%
    Glue 23.36%
    Meaty 23.28%
    Bloody 23.27%
    Skunky 22.24%
    Leathery 21.25%
    Sulfurous 21.12%
    Yeasty 21.08%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    7.57 (neutral)

    Molecular weight
    87.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    97°C

    Flash point

    • 9.33 ˚C est.

  • Synonyms

    • 34985-37-0
    • (S)-(-)-2-Methylbutylamine
    • (S)-2-Methylbutylamine
    • 1-Butanamine, 2-methyl-, (2S)-
    • (S)-(-)-2-Methyl-1-butylamine
    • (S)-2-Methylbutylamine, (-)-
    • D8Q8RZF45X
    • (S)-1-Amino-2-methylbutane
    • EINECS 252-307-6
    • (2S)-2-METHYLBUTYLAMINE
    • DTXSID301311845
    • 2-METHYLBUTYLAMINE, (S)-
    • (S)-2-METHYL-1-BUTANAMINE
    • (S)-2-METHYL-1-BUTYLAMINE
    • S)-(-)-2-METHYLBUTYLAMINE
    • 1-BUTANAMINE, 2-METHYL-, (S)-
    • RefChem:476008
    • DTXCID501741664
    • 252-307-6
    • (2S)-2-methylbutan-1-amine
    • MFCD00064430
    • (S)-2-methylbutan-1-amine
    • (s)-1-amino-2-methyl-butane
    • 2-Methyl-1-butanamine #
    • S-(-)-2-Methylbutylamine
    • UNII-D8Q8RZF45X
    • [(2S)-2-methylbutyl]amine
    • 2(S)-methylbutylamine
    • 20626-52-2
    • SCHEMBL172570
    • (2S)-2-methyl-1-butylamine
    • SCHEMBL7327498
    • SCHEMBL27597671
    • CHEBI:231981
    • AKOS006238137
    • (S)-(-)-2-Methylbutylamine, 95%
    • AS-60354
    • FM178873
    • DB-031994
    • NS00087817
    • G77772
    • EN300-2977538
    • 985M370
    • Q27276251
    • 20626-52-2

  • Applications

    2-Methylbutylamine, (S)- is a chiral primary amine primarily used as an intermediate in pharmaceutical synthesis, providing the amine functionality required for active compounds. It also serves as a precursor for agrochemical development and related biologically active molecules. Owing to its chiral nature, it is commonly employed as a building block in asymmetric synthesis and as a precursor for amine-containing cores in APIs. In the polymer and coatings industry, it can act as a curing agent or crosslinking component in epoxy and polyurethane systems, helping to improve adhesion and durability of coatings.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 728.57
    methanol 924.57
    isopropanol 395.99
    water 4.89
    ethyl acetate 329.78
    n-propanol 589.54
    acetone 283.09
    n-butanol 691.15
    acetonitrile 289.68
    DMF 170.23
    toluene 59.45
    isobutanol 346.43
    1,4-dioxane 354.28
    methyl acetate 259.5
    THF 877.62
    2-butanone 291.14
    n-pentanol 293.14
    sec-butanol 353.67
    n-hexane 37.5
    ethylene glycol 112.49
    NMP 297.46
    cyclohexane 50.48
    DMSO 331.79
    n-butyl acetate 814.38
    n-octanol 111.73
    chloroform 613.28
    n-propyl acetate 198.19
    acetic acid 826.57
    dichloromethane 390.06
    cyclohexanone 467.37
    propylene glycol 152.07
    isopropyl acetate 173.32
    DMAc 137.13
    2-ethoxyethanol 287.61
    isopentanol 430.59
    n-heptane 92.32
    ethyl formate 340.65
    1,2-dichloroethane 208.31
    n-hexanol 694.0
    2-methoxyethanol 593.18
    isobutyl acetate 113.63
    tetrachloromethane 210.57
    n-pentyl acetate 198.61
    transcutol 613.62
    n-heptanol 228.61
    ethylbenzene 21.26
    MIBK 130.09
    2-propoxyethanol 683.72
    tert-butanol 384.52
    MTBE 227.22
    2-butoxyethanol 341.01
    propionic acid 489.1
    o-xylene 38.15
    formic acid 315.96
    diethyl ether 256.57
    m-xylene 38.13
    p-xylene 34.65
    chlorobenzene 139.52
    dimethyl carbonate 34.63
    n-octane 19.28
    formamide 249.29
    cyclopentanone 587.44
    2-pentanone 271.84
    anisole 60.68
    cyclopentyl methyl ether 317.22
    gamma-butyrolactone 627.78
    1-methoxy-2-propanol 318.03
    pyridine 324.7
    3-pentanone 164.7
    furfural 499.26
    n-dodecane 9.1
    diethylene glycol 358.35
    diisopropyl ether 70.12
    tert-amyl alcohol 329.08
    acetylacetone 179.11
    n-hexadecane 9.41
    acetophenone 66.7
    methyl propionate 173.86
    isopentyl acetate 485.04
    trichloroethylene 419.48
    n-nonanol 96.79
    cyclohexanol 329.42
    benzyl alcohol 82.32
    2-ethylhexanol 406.45
    isooctanol 145.73
    dipropyl ether 347.26
    1,2-dichlorobenzene 105.12
    ethyl lactate 78.72
    propylene carbonate 343.64
    n-methylformamide 289.32
    2-pentanol 316.12
    n-pentane 50.45
    1-propoxy-2-propanol 619.23
    1-methoxy-2-propyl acetate 296.6
    2-(2-methoxypropoxy) propanol 115.6
    mesitylene 24.02
    ε-caprolactone 416.91
    p-cymene 58.61
    epichlorohydrin 422.65
    1,1,1-trichloroethane 272.46
    2-aminoethanol 270.31
    morpholine-4-carbaldehyde 275.24
    sulfolane 467.79
    2,2,4-trimethylpentane 26.55
    2-methyltetrahydrofuran 581.98
    n-hexyl acetate 174.91
    isooctane 18.87
    2-(2-butoxyethoxy)ethanol 213.61
    sec-butyl acetate 105.63
    tert-butyl acetate 166.02
    decalin 15.59
    glycerin 192.23
    diglyme 365.31
    acrylic acid 327.69
    isopropyl myristate 56.44
    n-butyric acid 936.27
    acetyl acetate 162.74
    di(2-ethylhexyl) phthalate 55.82
    ethyl propionate 116.77
    nitromethane 594.08
    1,2-diethoxyethane 327.2
    benzonitrile 162.65
    trioctyl phosphate 53.9
    1-bromopropane 171.22
    gamma-valerolactone 581.97
    n-decanol 67.49
    triethyl phosphate 94.04
    4-methyl-2-pentanol 140.24
    propionitrile 282.19
    vinylene carbonate 260.07
    1,1,2-trichlorotrifluoroethane 362.42
    DMS 71.82
    cumene 19.93
    2-octanol 107.23
    2-hexanone 182.98
    octyl acetate 80.95
    limonene 125.36
    1,2-dimethoxyethane 314.53
    ethyl orthosilicate 105.0
    tributyl phosphate 77.44
    diacetone alcohol 199.65
    N,N-dimethylaniline 33.14
    acrylonitrile 265.14
    aniline 165.41
    1,3-propanediol 479.63
    bromobenzene 107.74
    dibromomethane 271.83
    1,1,2,2-tetrachloroethane 353.93
    2-methyl-cyclohexyl acetate 182.79
    tetrabutyl urea 72.6
    diisobutyl methanol 147.65
    2-phenylethanol 173.46
    styrene 30.71
    dioctyl adipate 66.75
    dimethyl sulfate 53.03
    ethyl butyrate 364.09
    methyl lactate 95.93
    butyl lactate 165.04
    diethyl carbonate 160.57
    propanediol butyl ether 161.37
    triethyl orthoformate 237.45
    p-tert-butyltoluene 55.27
    methyl 4-tert-butylbenzoate 73.96
    morpholine 491.71
    tert-butylamine 249.61
    n-dodecanol 50.23
    dimethoxymethane 134.11
    ethylene carbonate 249.21
    cyrene 81.58
    2-ethoxyethyl acetate 186.77
    2-ethylhexyl acetate 377.66
    1,2,4-trichlorobenzene 116.4
    4-methylpyridine 239.49
    dibutyl ether 149.6
    2,6-dimethyl-4-heptanol 147.65
    DEF 219.46
    dimethyl isosorbide 226.29
    tetrachloroethylene 318.8
    eugenol 84.82
    triacetin 109.21
    span 80 162.14
    1,4-butanediol 131.26
    1,1-dichloroethane 242.04
    2-methyl-1-pentanol 217.46
    methyl formate 182.07
    2-methyl-1-butanol 392.51
    n-decane 16.98
    butyronitrile 392.77
    3,7-dimethyl-1-octanol 121.58
    1-chlorooctane 55.65
    1-chlorotetradecane 18.74
    n-nonane 18.2
    undecane 11.62
    tert-butylcyclohexane 19.55
    cyclooctane 18.02
    cyclopentanol 412.93
    tetrahydropyran 463.35
    tert-amyl methyl ether 156.75
    2,5,8-trioxanonane 196.56
    1-hexene 103.68
    2-isopropoxyethanol 164.47
    2,2,2-trifluoroethanol 199.97
    methyl butyrate 198.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction