2-Methyl-1,5-dioxaspiro[5.5]undecane

Overview IFRA Request a quote

  • Identifiers

    CAS number
    6413-26-9

    Molecular formula
    C10H18O2

    SMILES
    CC1CCOC2(O1)CCCCC2

  • Odor profile

    Fragrance
    Herbal 71.85%
    Woody 67.64%
    Mint 42.71%
    Camphoreous 36.92%
    Fresh 35.76%
    Spicy 35.03%
    Sweet 31.73%
    Amber 31.21%
    Green 31.03%
    Tobacco 28.91%

     

    Flavor
    Green 34.34%
    Vegetable 31.82%
    Sweet 30.01%
    Earthy 28.94%
    Caramel 27.41%
    Cauliflower 23.04%
    Warm 22.35%
    Musty 22.32%
    Metallic 22.11%
    Roasted 21.7%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    7.96 (neutral)

    Molecular weight
    170.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    223°C

    Flash point

    • 74.0 ˚C est.

  • Synonyms

    • 2-Methyl-1,5-dioxaspiro[5.5]undecane
    • 6413-26-9
    • 2-Methyl-1,5-dioxaspiro(5.5)undecane
    • 1,5-Dioxaspiro[5.5]undecane, 2-methyl-
    • 4-methyl-1,5-dioxaspiro[5.5]undecane
    • Cyclohexanone 1,3-butylene glycol ketal
    • 6C00W8M69N
    • 1,5-Dioxaspiro(5.5)undecane, 2-methyl-
    • EINECS 229-115-6
    • NSC 46270
    • UNII-6C00W8M69N
    • AI3-22544
    • NSC-46270
    • DTXSID60863794
    • (+/-)-2-METHYL-1,5-DIOXASPIRO(5.5)UNDECANE
    • 2-METHYL-1,5-DIOXASPIRO(5.5)UNDECANE, (+/-)-
    • NSC46270
    • SCHEMBL1472080
    • Cyclohexanone-1,3-butylene ketal
    • DTXCID50812372
    • AKOS006230053
    • 1,5-Dioxaspiro5.5undecane, 2-methyl-
    • 2,2-pentamethylene-4-methyl-1,3-dioxan
    • DB-279156
    • NS00012885
    • SR-01000390247
    • SR-01000390247-1
    • Q27264463
    • 229-115-6

  • Applications

    2-Methyl-1,5-dioxaspiro[5.5]undecane (CAS 6413-26-9) is primarily used as a fragrance ingredient/odorant in perfumery and cosmetics, contributing a stable note and occasionally functioning as a fixative. It also serves as an intermediate in organic synthesis, notably as a spiro acetal protecting group that can shield carbonyl functionalities during multi-step sequences. The compound may be used as a processing aid or specialty component in formulations for coatings, inks, and cleaning products, depending on formulation and regulatory constraints. In broader materials contexts, it may act as a precursor or functional additive in specialty polymers/plastics where a protected diol motif provides beneficial processing or performance characteristics.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 398.25
    methanol 429.66
    isopropanol 342.19
    water 1.06
    ethyl acetate 547.34
    n-propanol 388.5
    acetone 471.91
    n-butanol 367.72
    acetonitrile 460.68
    DMF 486.26
    toluene 542.6
    isobutanol 325.9
    1,4-dioxane 761.78
    methyl acetate 477.36
    THF 1063.13
    2-butanone 470.34
    n-pentanol 275.52
    sec-butanol 350.9
    n-hexane 155.17
    ethylene glycol 83.53
    NMP 665.9
    cyclohexane 319.0
    DMSO 638.24
    n-butyl acetate 543.08
    n-octanol 306.08
    chloroform 2836.89
    n-propyl acetate 387.03
    acetic acid 465.58
    dichloromethane 2328.13
    cyclohexanone 938.09
    propylene glycol 126.53
    isopropyl acetate 385.03
    DMAc 501.91
    2-ethoxyethanol 294.61
    isopentanol 323.02
    n-heptane 157.31
    ethyl formate 373.28
    1,2-dichloroethane 971.79
    n-hexanol 454.14
    2-methoxyethanol 404.17
    isobutyl acetate 284.95
    tetrachloromethane 445.87
    n-pentyl acetate 385.67
    transcutol 979.19
    n-heptanol 244.57
    ethylbenzene 281.05
    MIBK 318.97
    2-propoxyethanol 480.1
    tert-butanol 392.93
    MTBE 365.6
    2-butoxyethanol 305.3
    propionic acid 426.27
    o-xylene 333.52
    formic acid 111.82
    diethyl ether 460.44
    m-xylene 347.98
    p-xylene 367.48
    chlorobenzene 821.64
    dimethyl carbonate 205.03
    n-octane 69.64
    formamide 134.37
    cyclopentanone 882.7
    2-pentanone 429.08
    anisole 431.11
    cyclopentyl methyl ether 630.42
    gamma-butyrolactone 1075.67
    1-methoxy-2-propanol 373.82
    pyridine 885.68
    3-pentanone 401.21
    furfural 873.96
    n-dodecane 68.41
    diethylene glycol 278.32
    diisopropyl ether 192.79
    tert-amyl alcohol 345.58
    acetylacetone 519.02
    n-hexadecane 78.22
    acetophenone 437.33
    methyl propionate 421.61
    isopentyl acetate 451.72
    trichloroethylene 1880.83
    n-nonanol 263.36
    cyclohexanol 512.91
    benzyl alcohol 347.76
    2-ethylhexanol 313.02
    isooctanol 201.55
    dipropyl ether 396.58
    1,2-dichlorobenzene 743.62
    ethyl lactate 197.98
    propylene carbonate 734.28
    n-methylformamide 280.33
    2-pentanol 280.73
    n-pentane 141.27
    1-propoxy-2-propanol 381.71
    1-methoxy-2-propyl acetate 407.58
    2-(2-methoxypropoxy) propanol 347.44
    mesitylene 241.96
    ε-caprolactone 873.41
    p-cymene 234.28
    epichlorohydrin 983.68
    1,1,1-trichloroethane 1039.09
    2-aminoethanol 172.28
    morpholine-4-carbaldehyde 658.6
    sulfolane 1129.28
    2,2,4-trimethylpentane 78.98
    2-methyltetrahydrofuran 829.71
    n-hexyl acetate 585.96
    isooctane 61.15
    2-(2-butoxyethoxy)ethanol 420.64
    sec-butyl acetate 277.42
    tert-butyl acetate 363.53
    decalin 134.91
    glycerin 162.04
    diglyme 704.24
    acrylic acid 351.16
    isopropyl myristate 271.46
    n-butyric acid 582.41
    acetyl acetate 437.39
    di(2-ethylhexyl) phthalate 241.01
    ethyl propionate 360.86
    nitromethane 574.89
    1,2-diethoxyethane 422.86
    benzonitrile 640.82
    trioctyl phosphate 183.98
    1-bromopropane 720.39
    gamma-valerolactone 928.74
    n-decanol 198.05
    triethyl phosphate 224.14
    4-methyl-2-pentanol 186.4
    propionitrile 502.26
    vinylene carbonate 702.32
    1,1,2-trichlorotrifluoroethane 646.51
    DMS 414.88
    cumene 210.4
    2-octanol 191.66
    2-hexanone 347.15
    octyl acetate 328.33
    limonene 330.93
    1,2-dimethoxyethane 554.85
    ethyl orthosilicate 195.14
    tributyl phosphate 240.98
    diacetone alcohol 316.37
    N,N-dimethylaniline 285.27
    acrylonitrile 528.53
    aniline 478.26
    1,3-propanediol 241.64
    bromobenzene 1031.48
    dibromomethane 1668.66
    1,1,2,2-tetrachloroethane 1428.08
    2-methyl-cyclohexyl acetate 355.87
    tetrabutyl urea 268.79
    diisobutyl methanol 187.82
    2-phenylethanol 365.28
    styrene 387.15
    dioctyl adipate 361.57
    dimethyl sulfate 311.98
    ethyl butyrate 413.48
    methyl lactate 215.25
    butyl lactate 274.18
    diethyl carbonate 300.22
    propanediol butyl ether 289.89
    triethyl orthoformate 286.52
    p-tert-butyltoluene 219.59
    methyl 4-tert-butylbenzoate 389.52
    morpholine 689.69
    tert-butylamine 319.68
    n-dodecanol 159.31
    dimethoxymethane 404.16
    ethylene carbonate 613.51
    cyrene 288.14
    2-ethoxyethyl acetate 411.47
    2-ethylhexyl acetate 387.96
    1,2,4-trichlorobenzene 830.65
    4-methylpyridine 820.18
    dibutyl ether 414.1
    2,6-dimethyl-4-heptanol 187.82
    DEF 486.02
    dimethyl isosorbide 561.22
    tetrachloroethylene 960.35
    eugenol 324.6
    triacetin 538.78
    span 80 385.94
    1,4-butanediol 125.84
    1,1-dichloroethane 1015.34
    2-methyl-1-pentanol 261.48
    methyl formate 261.73
    2-methyl-1-butanol 312.82
    n-decane 106.96
    butyronitrile 525.93
    3,7-dimethyl-1-octanol 301.9
    1-chlorooctane 316.81
    1-chlorotetradecane 140.68
    n-nonane 109.43
    undecane 81.79
    tert-butylcyclohexane 114.35
    cyclooctane 125.68
    cyclopentanol 510.36
    tetrahydropyran 831.42
    tert-amyl methyl ether 308.44
    2,5,8-trioxanonane 521.48
    1-hexene 344.7
    2-isopropoxyethanol 236.9
    2,2,2-trifluoroethanol 159.24
    methyl butyrate 474.11

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction