2-Methyl-1-butanol

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    137-32-6

    Molecular formula
    C5H12O

    SMILES
    CCC(C)CO

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

    Retention indicies (RI)

    • DB5: 749.0
    • Carbowax: 1221.33

  • Odor profile

    Alcoholic 79.42%
    Fermented 79.18%
    Ethereal 72.34%
    Solvent 69.19%
    Oily 67.45%
    Sweet 60.83%
    Winey 56.66%
    Pungent 45.69%
    Musty 44.45%
    Fruity 42.92%

    Scent© AI

    Odor threshold

    • Odor Threshold Low: 0.12 [mmHg]. Odor Threshold High: 0.23 [mmHg]. [Merck Index] Odor threshold from CHEMINFO
    • 0.045 mg/cu m (Odor low) 0.83 mg/cu m (Odor high)

  • Properties

    XLogP3-AA
    1.2

    pKa est.
    8.76 (weak base)

    Molecular weight
    88.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Melting point expt.

    • FREEZING POINT: LESS THAN -70 °C

    Boiling point

    • 128 °C @ 760 MM HG
    • 128.00 to 130.00 °C. @ 760.00 mm Hg
    • 128 °C

    Flash point est.
    36.25 ˚C

    Flash point expt.

    • 50 °C
    • 122 °F (50 °C) (OPEN CUP)
    • 50 °C o.c.

    Solubility expt.

    • MISCIBLE WITH ALC & ETHER
    • Sol in acetone
    • Water solubility: 30,000 mg/l : 25 °C
    • Solubility in water, g/100ml at 25 °C: 3.0 (moderate)
    • Very slightly soluble in water; 50% soluble in heptane, triacetin
    • soluble (in ethanol)

  • Synonyms

    • 2-METHYL-1-BUTANOL
    • 2-Methylbutan-1-ol
    • 137-32-6
    • 1-Butanol, 2-methyl-
    • Active amyl alcohol
    • sec-Butylcarbinol
    • 2-Methylbutanol
    • DL-2-Methyl-1-butanol
    • 2-Methyl-n-butanol
    • 2-Methylbutyl alcohol
    • Active primary amyl alcohol
    • Primary active amyl alcohol
    • 2-Methyl butanol-1
    • (+/-)-2-Methyl-1-butanol
    • dl-sec-Butyl carbinol
    • L-2-Methyl-1-butanol
    • sec-Butyl carbinol
    • NSC 8431
    • Methyl-2-butan-1-ol
    • 2-Methyl-Butan-1-Ol
    • HSDB 5626
    • UNII-7VTJ239ASU
    • EINECS 205-289-9
    • EINECS 252-163-4
    • (1)-2-Methylbutan-1-ol
    • 7VTJ239ASU
    • CH3CH2CH(CH3)CH2OH
    • BRN 1718810
    • CCRIS 8805
    • D-2-METHYL-1-BUTANOL
    • Butanol, 2-methyl-
    • 3-Methyl iso-butanol
    • DTXSID5027069
    • CHEBI:48945
    • AI3-24190
    • NSC-8431
    • ( inverted exclamation markA)-2-Methyl-1-butanol
    • DL-2-METHYL-1-BUTANOL, PRACT
    • 2-Methyl-(S)-1-Butanol
    • 2-Methyl-(2S)-1-Butanol
    • DTXCID107069
    • FEMA NO. 3998
    • EC 205-289-9
    • 2-METHYL-1-BUTANOL [MI]
    • 2-Methyl-(.+/-.)-1-Butanol
    • 4-01-00-01666 (Beilstein Handbook Reference)
    • 2-METHYL-1-BUTANOL [HSDB]
    • 2-METHYL-1-BUTANOL,(+/-)-
    • (+/-)-2-METHYL-1-BUTANOL [FHFI]
    • 34713-94-5
    • (-)-2-methylbutanol
    • CAS-137-32-6
    • 2methylbutanol
    • 2Methylnbutanol
    • secButylcarbinol
    • 2-methyl-butanol
    • 2Methyl butanol1
    • dlsecButyl carbinol
    • 1Butanol, 2methyl
    • 2Methylbutyl alcohol
    • MFCD00004743
    • DL-sec-Butylcarbinol
    • (-)2-methylbutanol
    • 2-methyl 1-butanol
    • (+)-2-methylbutanol
    • (RS)-2-methyl-1-butanol
    • CHEMBL451923
    • 2-Methyl-(+/-)-1-butanol
    • 2-Methyl-1-butanol, >=99%
    • NSC8431
    • WLN: Q1Y2 & 1
    • Tox21_201558
    • Tox21_303200
    • LMFA05000104
    • STL185573
    • 2-Methyl-1-butanol, >=99%, FG
    • AKOS009159118
    • FM29134
    • 2-Methyl-1-butanol, analytical standard
    • NCGC00249069-01
    • NCGC00256976-01
    • NCGC00259107-01
    • 2-Methyl-1-butanol, natural, 99%, FG
    • DB-003288
    • M0175
    • NS00010145
    • EN300-126214
    • Q209425
    • (+/-)-2-Methyl-1-butanol, >=98.0% (GC)
    • F0001-0469

  • Applications

    2-Methyl-1-butanol (also known as isoamyl alcohol) has a mild fruity odor and acts as a versatile organic solvent in paints, printing inks, adhesives and cleaners thanks to its strong solvency and moderate evaporation rate; in the flavor and fragrance industry it is the main precursor of isoamyl acetate that imparts banana and pear notes and is incorporated into perfumes, creams and toiletries; in pharmaceutical, veterinary and agrochemical manufacture it serves as an intermediate for carboxylate and sulfonate derivatives; additionally, 2-Methyl-1-butanol is being explored as a biofuel additive, a cold-flow improver for diesel, an extraction solvent in chromatographic analysis and a pretreatment agent for lignocellulosic biomass.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 899.49
    methanol 932.78
    isopropanol 564.35
    water 5.1
    ethyl acetate 242.17
    n-propanol 692.46
    acetone 183.76
    n-butanol 732.86
    acetonitrile 210.25
    DMF 120.4
    toluene 34.12
    isobutanol 465.75
    1,4-dioxane 410.04
    methyl acetate 192.12
    THF 690.8
    2-butanone 216.12
    n-pentanol 369.03
    sec-butanol 481.6
    n-hexane 53.24
    ethylene glycol 154.81
    NMP 201.59
    cyclohexane 59.83
    DMSO 295.77
    n-butyl acetate 485.56
    n-octanol 167.27
    chloroform 459.57
    n-propyl acetate 191.82
    acetic acid 777.33
    dichloromethane 303.93
    cyclohexanone 381.87
    propylene glycol 200.99
    isopropyl acetate 146.29
    DMAc 95.4
    2-ethoxyethanol 331.28
    isopentanol 506.74
    n-heptane 78.72
    ethyl formate 215.25
    1,2-dichloroethane 179.81
    n-hexanol 632.91
    2-methoxyethanol 607.57
    isobutyl acetate 117.2
    tetrachloromethane 154.37
    n-pentyl acetate 182.14
    transcutol 968.77
    n-heptanol 235.91
    ethylbenzene 25.32
    MIBK 124.51
    2-propoxyethanol 599.12
    tert-butanol 618.8
    MTBE 255.77
    2-butoxyethanol 359.06
    propionic acid 474.32
    o-xylene 31.41
    formic acid 294.32
    diethyl ether 234.17
    m-xylene 31.5
    p-xylene 39.56
    chlorobenzene 90.92
    dimethyl carbonate 24.01
    n-octane 22.93
    formamide 228.13
    cyclopentanone 363.18
    2-pentanone 192.18
    anisole 71.89
    cyclopentyl methyl ether 246.76
    gamma-butyrolactone 407.93
    1-methoxy-2-propanol 349.18
    pyridine 222.78
    3-pentanone 107.79
    furfural 334.67
    n-dodecane 13.15
    diethylene glycol 391.02
    diisopropyl ether 81.3
    tert-amyl alcohol 469.75
    acetylacetone 138.24
    n-hexadecane 13.72
    acetophenone 70.08
    methyl propionate 121.05
    isopentyl acetate 352.78
    trichloroethylene 357.72
    n-nonanol 142.09
    cyclohexanol 390.82
    benzyl alcohol 92.95
    2-ethylhexanol 386.2
    isooctanol 192.1
    dipropyl ether 260.88
    1,2-dichlorobenzene 86.91
    ethyl lactate 81.59
    propylene carbonate 255.81
    n-methylformamide 195.62
    2-pentanol 379.56
    n-pentane 54.44
    1-propoxy-2-propanol 525.58
    1-methoxy-2-propyl acetate 247.64
    2-(2-methoxypropoxy) propanol 196.6
    mesitylene 25.52
    ε-caprolactone 357.03
    p-cymene 53.9
    epichlorohydrin 351.56
    1,1,1-trichloroethane 208.6
    2-aminoethanol 376.99
    morpholine-4-carbaldehyde 263.39
    sulfolane 376.04
    2,2,4-trimethylpentane 32.81
    2-methyltetrahydrofuran 551.13
    n-hexyl acetate 210.61
    isooctane 29.49
    2-(2-butoxyethoxy)ethanol 340.51
    sec-butyl acetate 116.93
    tert-butyl acetate 165.93
    decalin 24.37
    glycerin 280.23
    diglyme 494.49
    acrylic acid 311.24
    isopropyl myristate 74.37
    n-butyric acid 809.92
    acetyl acetate 118.9
    di(2-ethylhexyl) phthalate 72.87
    ethyl propionate 114.53
    nitromethane 449.67
    1,2-diethoxyethane 303.21
    benzonitrile 135.79
    trioctyl phosphate 69.45
    1-bromopropane 148.14
    gamma-valerolactone 450.62
    n-decanol 102.18
    triethyl phosphate 79.86
    4-methyl-2-pentanol 191.29
    propionitrile 214.1
    vinylene carbonate 191.3
    1,1,2-trichlorotrifluoroethane 337.67
    DMS 78.61
    cumene 29.0
    2-octanol 141.69
    2-hexanone 186.24
    octyl acetate 96.78
    limonene 106.8
    1,2-dimethoxyethane 342.77
    ethyl orthosilicate 90.47
    tributyl phosphate 84.83
    diacetone alcohol 226.62
    N,N-dimethylaniline 45.52
    acrylonitrile 192.85
    aniline 115.51
    1,3-propanediol 585.33
    bromobenzene 67.71
    dibromomethane 223.03
    1,1,2,2-tetrachloroethane 303.22
    2-methyl-cyclohexyl acetate 170.08
    tetrabutyl urea 80.62
    diisobutyl methanol 175.47
    2-phenylethanol 164.28
    styrene 30.86
    dioctyl adipate 99.3
    dimethyl sulfate 40.13
    ethyl butyrate 274.79
    methyl lactate 78.82
    butyl lactate 168.28
    diethyl carbonate 134.18
    propanediol butyl ether 255.73
    triethyl orthoformate 179.85
    p-tert-butyltoluene 50.81
    methyl 4-tert-butylbenzoate 103.01
    morpholine 557.54
    tert-butylamine 396.97
    n-dodecanol 74.43
    dimethoxymethane 100.31
    ethylene carbonate 180.8
    cyrene 120.85
    2-ethoxyethyl acetate 175.72
    2-ethylhexyl acetate 265.67
    1,2,4-trichlorobenzene 97.29
    4-methylpyridine 155.42
    dibutyl ether 169.66
    2,6-dimethyl-4-heptanol 175.47
    DEF 166.83
    dimethyl isosorbide 279.8
    tetrachloroethylene 287.72
    eugenol 126.69
    triacetin 138.14
    span 80 245.94
    1,4-butanediol 180.21
    1,1-dichloroethane 192.28
    2-methyl-1-pentanol 302.02
    methyl formate 113.43
    2-methyl-1-butanol 452.46
    n-decane 24.5
    butyronitrile 315.52
    3,7-dimethyl-1-octanol 175.97
    1-chlorooctane 78.09
    1-chlorotetradecane 27.05
    n-nonane 25.68
    undecane 17.14
    tert-butylcyclohexane 30.76
    cyclooctane 20.22
    cyclopentanol 433.57
    tetrahydropyran 475.14
    tert-amyl methyl ether 173.76
    2,5,8-trioxanonane 290.9
    1-hexene 134.98
    2-isopropoxyethanol 213.11
    2,2,2-trifluoroethanol 189.05
    methyl butyrate 192.74

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Cardamom (Costa Rica) 8000-66-6 Elettaria cardamomum (L.) Maton, fam. Zingiberaceae 0.01%
Roman chamomile (India) 8015-92-7 Anthemis nobilis L., fam. Asteraceae (Compositae) 0.02%
Eriocephalus punctualis Eriocephalus punctualis DC., fam. Eriocaulaceae 0.5%
Laurel leaf (USA) 8006-78-8 Laurus nobilis L., fam. Lauraceae 0.03%
Myrtle leaf, cultivated (Spain) 8008-46-6 Myrtus communis L., fam. Myrtaceae 0.14%
Myrtle leaf, wildgrowing (Spain) 8008-46-6 Myrtus communis L., fam. Myrtaceae 0.11%
Rose (Turkey) 6 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.05%
Rose (Bulgaria) 3a 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.05%
Truffle, black (Perigord) Tuber melanosporum, fam. Ascomycetae 17.0%
Santolina chamaecyparisus (Egypt) 84961-58-0 Santolina chamaecyparisus L., fam. Asteraceae (Compositae) 0.01%
Rose (Bulgaria) 2 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.05%
Myrtle leaf (Spain) 8008-46-6 Myrtus communis L., fam. Myrtaceae 0.11%
Myrtle flower (Spain) 8008-46-6 Myrtus communis L., fam. Myrtaceae 0.1%
Myrtle unripe fruits (Spain) 8008-46-6 Myrtus communis L., fam. Myrtaceae 0.07%
Daylily, Headspace Living Flower 1 Hemerocallis minor hybrid, fam. Liliaceae 0.07%
Daylily, Headspace Living Flower 2 Hemerocallis, ssp. Satin Glass, fam. Liliaceae 2.59%
Myrtle leaf (Morocco) 3 8008-46-6 Myrtus communis L., fam. Myrtaceae 0.02%
Myrtle leaf (Albania) 1 8008-46-6 Myrtus communis L., fam. Myrtaceae 0.08%
Bouea macrophylla fruit (Malaysia) Bouea macrophylla Grif. (B. gandaria Blume x Miq., fam. Anacardiaceae 0.07%
Truffle, white (Italy) Tuber magnatum Pico, fam. Ascomycetae 5.0%
Rose (Bulgaria) 3b 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.01%
Rose (Turkey) 4 8007-01-7 Rosa damascena Mill., fam. Rosaceae 0.27%
Rose (Turkey) 5 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.1%
Psidium cattleianum fruit (R‚union Island) Psidium cattleianum Sabine, fam. Myrtaceae 0.7%
Mullilam leaf (India) Zanthoxylum rhetsa D.C. syn. Z. limonella (Dennst.) Alston, fam. Rutaceae 0.2%
Truffle, Asian Tuber indicum Cooke et Mass. (T. himalayense Zhang-Minter),fam.Ascomycetae 10.0%