2-Methoxyfuran

Overview IFRA Request a quote

  • Identifiers

    CAS number
    25414-22-6

    Molecular formula
    C5H6O2

    SMILES
    COC1=CC=CO1

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Ethereal 72.4%
    Sweet 69.1%
    Nutty 47.86%
    Burnt 47.35%
    Spicy 41.71%
    Fruity 39.91%
    Earthy 36.6%
    Coffee 36.33%
    Musty 36.06%
    Rummy 35.97%

     

    Flavor
    Sweet 86.47%
    Bitter 36.07%
    Green 34.62%
    Coffee 33.8%
    Vanilla 33.31%
    Nutty 32.56%
    Musty 32.39%
    Earthy 32.3%
    Ethereal 29.42%
    Fruity 28.65%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    6.48 (neutral)

    Molecular weight
    98.1 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    126°C

    Flash point

    • 17.38 ˚C est.

  • Synonyms

    • 2-Methoxyfuran
    • 25414-22-6
    • 25Y8I1P35T
    • DTXSID00180078
    • RefChem:474656
    • DTXCID10102569
    • 246-953-8
    • Furan, 2-methoxy-
    • 2-Furyl methyl ether
    • MFCD00003227
    • 2-methoxy furan
    • UNII-25Y8I1P35T
    • 2-methoxy-furan
    • Furan,2-methoxy-
    • EINECS 246-953-8
    • 2-Methoxyfuran, 97%
    • 2-Furyl methyl ether #
    • SCHEMBL170531
    • SCHEMBL446578
    • SCHEMBL448098
    • SCHEMBL826030
    • SCHEMBL827212
    • SCHEMBL6847362
    • GEO-02985
    • AKOS015912861
    • NCGC00166235-01
    • DB-008218
    • M0936
    • NS00049740
    • F10347
    • Q27254009
    • InChI=1/C5H6O2/c1-6-5-3-2-4-7-5/h2-4H,1H
    • 25414-22-6

  • Applications

    2-Methoxyfuran (CAS 25414-22-6) is used as a chemical intermediate and building block in organic synthesis, with applications across several industrial sectors. In perfumery and flavor chemistry, it is commonly evaluated as a precursor for fragrance and aroma compounds. In pharmaceuticals, it can serve as an intermediate in the synthesis of heterocyclic compounds. In polymers and coatings, it can function as a reactive intermediate or processing aid for furan-containing monomers and formulations. It also appears in cosmetics/personal care and household products as a fragrance ingredient or solvent/processing medium, and may serve as a solvent or processing aid in cleaning formulations. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1546.69
    methanol 2369.08
    isopropanol 1087.72
    water 97.49
    ethyl acetate 1035.33
    n-propanol 1135.04
    acetone 1287.28
    n-butanol 1012.07
    acetonitrile 1712.36
    DMF 1630.56
    toluene 549.55
    isobutanol 918.47
    1,4-dioxane 1602.22
    methyl acetate 1046.09
    THF 1876.84
    2-butanone 1062.14
    n-pentanol 826.08
    sec-butanol 1054.91
    n-hexane 200.96
    ethylene glycol 469.58
    NMP 1249.07
    cyclohexane 265.14
    DMSO 1623.43
    n-butyl acetate 417.53
    n-octanol 292.99
    chloroform 2162.89
    n-propyl acetate 557.36
    acetic acid 1806.26
    dichloromethane 2737.81
    cyclohexanone 867.16
    propylene glycol 398.48
    isopropyl acetate 535.32
    DMAc 1324.62
    2-ethoxyethanol 1536.34
    isopentanol 910.63
    n-heptane 136.21
    ethyl formate 761.75
    1,2-dichloroethane 1359.79
    n-hexanol 475.91
    2-methoxyethanol 2000.53
    isobutyl acetate 313.55
    tetrachloromethane 573.52
    n-pentyl acetate 286.46
    transcutol 1650.67
    n-heptanol 246.64
    ethylbenzene 250.95
    MIBK 502.91
    2-propoxyethanol 872.15
    tert-butanol 1452.88
    MTBE 1234.33
    2-butoxyethanol 485.61
    propionic acid 909.72
    o-xylene 331.78
    formic acid 1292.12
    diethyl ether 1355.99
    m-xylene 325.12
    p-xylene 336.62
    chlorobenzene 565.87
    dimethyl carbonate 399.33
    n-octane 62.55
    formamide 1592.85
    cyclopentanone 1102.48
    2-pentanone 808.09
    anisole 636.07
    cyclopentyl methyl ether 972.73
    gamma-butyrolactone 1160.75
    1-methoxy-2-propanol 1181.0
    pyridine 1251.55
    3-pentanone 689.52
    furfural 1152.81
    n-dodecane 48.25
    diethylene glycol 721.46
    diisopropyl ether 397.77
    tert-amyl alcohol 1213.74
    acetylacetone 729.82
    n-hexadecane 51.97
    acetophenone 435.74
    methyl propionate 762.22
    isopentyl acetate 356.94
    trichloroethylene 1974.62
    n-nonanol 255.16
    cyclohexanol 806.43
    benzyl alcohol 523.51
    2-ethylhexanol 296.15
    isooctanol 225.78
    dipropyl ether 457.4
    1,2-dichlorobenzene 466.36
    ethyl lactate 238.35
    propylene carbonate 535.73
    n-methylformamide 1290.74
    2-pentanol 761.23
    n-pentane 238.27
    1-propoxy-2-propanol 530.4
    1-methoxy-2-propyl acetate 382.08
    2-(2-methoxypropoxy) propanol 426.54
    mesitylene 218.32
    ε-caprolactone 719.47
    p-cymene 152.56
    epichlorohydrin 1762.38
    1,1,1-trichloroethane 1163.58
    2-aminoethanol 833.82
    morpholine-4-carbaldehyde 1246.66
    sulfolane 1131.92
    2,2,4-trimethylpentane 140.93
    2-methyltetrahydrofuran 1631.48
    n-hexyl acetate 391.13
    isooctane 94.45
    2-(2-butoxyethoxy)ethanol 564.35
    sec-butyl acetate 355.49
    tert-butyl acetate 569.14
    decalin 116.08
    glycerin 577.98
    diglyme 1134.69
    acrylic acid 833.12
    isopropyl myristate 177.83
    n-butyric acid 1006.26
    acetyl acetate 532.66
    di(2-ethylhexyl) phthalate 159.96
    ethyl propionate 488.05
    nitromethane 2218.21
    1,2-diethoxyethane 725.84
    benzonitrile 623.54
    trioctyl phosphate 113.51
    1-bromopropane 948.98
    gamma-valerolactone 1242.97
    n-decanol 187.78
    triethyl phosphate 181.34
    4-methyl-2-pentanol 410.04
    propionitrile 1116.73
    vinylene carbonate 554.76
    1,1,2-trichlorotrifluoroethane 997.74
    DMS 292.95
    cumene 197.72
    2-octanol 196.32
    2-hexanone 558.65
    octyl acetate 211.76
    limonene 233.95
    1,2-dimethoxyethane 1745.74
    ethyl orthosilicate 191.3
    tributyl phosphate 150.99
    diacetone alcohol 605.49
    N,N-dimethylaniline 446.33
    acrylonitrile 1192.81
    aniline 748.84
    1,3-propanediol 1070.35
    bromobenzene 550.71
    dibromomethane 1685.43
    1,1,2,2-tetrachloroethane 1272.28
    2-methyl-cyclohexyl acetate 263.17
    tetrabutyl urea 210.84
    diisobutyl methanol 209.17
    2-phenylethanol 340.2
    styrene 342.41
    dioctyl adipate 232.55
    dimethyl sulfate 506.76
    ethyl butyrate 383.33
    methyl lactate 336.84
    butyl lactate 189.16
    diethyl carbonate 255.97
    propanediol butyl ether 355.2
    triethyl orthoformate 266.83
    p-tert-butyltoluene 149.25
    methyl 4-tert-butylbenzoate 349.1
    morpholine 1846.16
    tert-butylamine 995.99
    n-dodecanol 148.34
    dimethoxymethane 1320.44
    ethylene carbonate 478.62
    cyrene 431.18
    2-ethoxyethyl acetate 390.55
    2-ethylhexyl acetate 287.64
    1,2,4-trichlorobenzene 506.2
    4-methylpyridine 1107.12
    dibutyl ether 382.15
    2,6-dimethyl-4-heptanol 209.17
    DEF 994.22
    dimethyl isosorbide 607.82
    tetrachloroethylene 1028.54
    eugenol 345.4
    triacetin 332.41
    span 80 289.78
    1,4-butanediol 554.3
    1,1-dichloroethane 1455.11
    2-methyl-1-pentanol 727.85
    methyl formate 977.26
    2-methyl-1-butanol 902.36
    n-decane 77.49
    butyronitrile 1074.84
    3,7-dimethyl-1-octanol 307.99
    1-chlorooctane 208.78
    1-chlorotetradecane 92.67
    n-nonane 80.61
    undecane 58.55
    tert-butylcyclohexane 119.51
    cyclooctane 104.0
    cyclopentanol 939.19
    tetrahydropyran 1340.86
    tert-amyl methyl ether 926.66
    2,5,8-trioxanonane 765.73
    1-hexene 443.89
    2-isopropoxyethanol 943.39
    2,2,2-trifluoroethanol 682.85
    methyl butyrate 624.01

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction