2-Isopropyl-p-cresol

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    4427-56-9

    Molecular formula
    C10H14O

    SMILES
    CC1=CC(=C(C=C1)O)C(C)C

    Retention indicies (RI)

    • Carbowax: 1586.0

  • Odor profile

    Phenolic 84.71%
    Spicy 72.66%
    Smoky 66.49%
    Medicinal 64.64%
    Leathery 55.96%
    Woody 53.81%
    Herbal 51.06%
    Burnt 43.13%
    Animal 34.33%
    Camphoreous 33.38%

    Scent© AI

  • Properties

    XLogP3-AA
    3.1

    Molecular weight
    150.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    232°C

    Flash point est.
    103.42 ˚C

  • Synonyms

    • 2-Isopropyl-4-methylphenol
    • 4427-56-9
    • 4-Methyl-2-isopropylphenol
    • 2-Isopropyl-p-cresol
    • Phenol, 4-methyl-2-(1-methylethyl)-
    • m-Cymen-4-ol
    • 4-methyl-2-propan-2-ylphenol
    • p-Cresol, 2-isopropyl-
    • Phenol, 2-isopropyl-4-methyl-
    • 1-Hydroxy-4-methyl-2-isopropylbenzene
    • RIM60IN3PY
    • EINECS 224-611-9
    • NSC 62110
    • 2-isopropyl-4-methyl-phenol
    • m-Cymen-6-ol
    • 4-Methyl-2-isopropylphenol (Isothymol)
    • BRN 1860557
    • AI3-01514
    • MFCD00151522
    • NSC-62110
    • DTXSID2052104
    • 4-METHYL-2-(1-METHYLETHYL)PHENOL
    • UNII-RIM60IN3PY
    • m-Cymen-4-ol (8CI)
    • SCHEMBL852892
    • CHEMBL2288299
    • DTXCID4030671
    • NSC62110
    • AKOS006282268
    • CS-W006880
    • DS-5182
    • MB00760
    • SY114698
    • DB-051204
    • NS00012725
    • Q27288134
    • 224-611-9
    • 4-Methyl-2-isopropylphenol (Isothymol); 2-Isopropyl-4-methylphenol, 2-Isopropyl-p-cresol, 4-Methyl-2-isopropylphenol, Isothymol

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2527.43
    methanol 1919.44
    isopropanol 2461.52
    water 1.04
    ethyl acetate 2156.08
    n-propanol 2355.27
    acetone 3800.28
    n-butanol 1841.23
    acetonitrile 3482.07
    DMF 2766.48
    toluene 677.19
    isobutanol 1694.11
    1,4-dioxane 4440.51
    methyl acetate 2172.86
    THF 7045.82
    2-butanone 2720.06
    n-pentanol 1171.25
    sec-butanol 1805.55
    n-hexane 622.88
    ethylene glycol 214.45
    NMP 1438.05
    cyclohexane 412.6
    DMSO 2348.67
    n-butyl acetate 1645.89
    n-octanol 746.2
    chloroform 3041.55
    n-propyl acetate 1190.26
    acetic acid 728.53
    dichloromethane 2988.71
    cyclohexanone 2530.29
    propylene glycol 368.6
    isopropyl acetate 1098.84
    DMAc 980.64
    2-ethoxyethanol 1083.67
    isopentanol 1265.81
    n-heptane 255.96
    ethyl formate 1294.11
    1,2-dichloroethane 2345.83
    n-hexanol 1959.63
    2-methoxyethanol 1698.7
    isobutyl acetate 735.92
    tetrachloromethane 501.52
    n-pentyl acetate 711.92
    transcutol 1601.69
    n-heptanol 713.82
    ethylbenzene 453.59
    MIBK 1068.77
    2-propoxyethanol 1882.09
    tert-butanol 2329.4
    MTBE 2748.32
    2-butoxyethanol 827.71
    propionic acid 1014.84
    o-xylene 358.93
    formic acid 153.29
    diethyl ether 3241.15
    m-xylene 488.59
    p-xylene 500.66
    chlorobenzene 808.17
    dimethyl carbonate 489.4
    n-octane 148.06
    formamide 326.07
    cyclopentanone 3610.3
    2-pentanone 2232.42
    anisole 804.03
    cyclopentyl methyl ether 2366.41
    gamma-butyrolactone 3115.96
    1-methoxy-2-propanol 1557.72
    pyridine 1704.53
    3-pentanone 1401.55
    furfural 1221.23
    n-dodecane 104.12
    diethylene glycol 845.35
    diisopropyl ether 742.3
    tert-amyl alcohol 1519.37
    acetylacetone 1355.3
    n-hexadecane 119.36
    acetophenone 508.99
    methyl propionate 1490.81
    isopentyl acetate 1213.74
    trichloroethylene 2791.99
    n-nonanol 594.9
    cyclohexanol 1245.55
    benzyl alcohol 461.93
    2-ethylhexanol 772.8
    isooctanol 551.35
    dipropyl ether 1201.82
    1,2-dichlorobenzene 555.85
    ethyl lactate 348.49
    propylene carbonate 1245.19
    n-methylformamide 1466.47
    2-pentanol 1331.65
    n-pentane 425.6
    1-propoxy-2-propanol 1234.9
    1-methoxy-2-propyl acetate 944.37
    2-(2-methoxypropoxy) propanol 436.57
    mesitylene 311.54
    ε-caprolactone 1724.03
    p-cymene 237.09
    epichlorohydrin 3678.85
    1,1,1-trichloroethane 1917.55
    2-aminoethanol 553.33
    morpholine-4-carbaldehyde 1507.13
    sulfolane 2477.55
    2,2,4-trimethylpentane 146.84
    2-methyltetrahydrofuran 4140.52
    n-hexyl acetate 1070.89
    isooctane 162.57
    2-(2-butoxyethoxy)ethanol 769.6
    sec-butyl acetate 673.95
    tert-butyl acetate 1073.53
    decalin 183.11
    glycerin 325.54
    diglyme 1342.34
    acrylic acid 567.45
    isopropyl myristate 369.25
    n-butyric acid 1385.59
    acetyl acetate 657.8
    di(2-ethylhexyl) phthalate 216.36
    ethyl propionate 865.49
    nitromethane 2083.45
    1,2-diethoxyethane 1261.8
    benzonitrile 747.98
    trioctyl phosphate 231.37
    1-bromopropane 1903.88
    gamma-valerolactone 2866.13
    n-decanol 450.07
    triethyl phosphate 223.71
    4-methyl-2-pentanol 643.42
    propionitrile 2476.39
    vinylene carbonate 847.02
    1,1,2-trichlorotrifluoroethane 827.06
    DMS 554.68
    cumene 297.82
    2-octanol 563.46
    2-hexanone 1382.82
    octyl acetate 499.93
    limonene 406.09
    1,2-dimethoxyethane 2365.45
    ethyl orthosilicate 235.67
    tributyl phosphate 247.83
    diacetone alcohol 944.48
    N,N-dimethylaniline 430.51
    acrylonitrile 2058.15
    aniline 665.9
    1,3-propanediol 933.34
    bromobenzene 845.78
    dibromomethane 2198.91
    1,1,2,2-tetrachloroethane 2042.25
    2-methyl-cyclohexyl acetate 462.92
    tetrabutyl urea 297.27
    diisobutyl methanol 400.66
    2-phenylethanol 644.86
    styrene 518.25
    dioctyl adipate 354.41
    dimethyl sulfate 597.88
    ethyl butyrate 778.94
    methyl lactate 417.7
    butyl lactate 391.58
    diethyl carbonate 393.82
    propanediol butyl ether 636.02
    triethyl orthoformate 415.71
    p-tert-butyltoluene 263.11
    methyl 4-tert-butylbenzoate 437.97
    morpholine 4118.0
    tert-butylamine 1478.18
    n-dodecanol 346.67
    dimethoxymethane 1986.8
    ethylene carbonate 884.11
    cyrene 389.31
    2-ethoxyethyl acetate 725.2
    2-ethylhexyl acetate 853.33
    1,2,4-trichlorobenzene 561.51
    4-methylpyridine 1583.85
    dibutyl ether 925.54
    2,6-dimethyl-4-heptanol 400.66
    DEF 1477.74
    dimethyl isosorbide 744.04
    tetrachloroethylene 1178.58
    eugenol 422.61
    triacetin 427.77
    span 80 447.23
    1,4-butanediol 394.93
    1,1-dichloroethane 2874.87
    2-methyl-1-pentanol 830.04
    methyl formate 1207.39
    2-methyl-1-butanol 1187.72
    n-decane 179.89
    butyronitrile 2356.42
    3,7-dimethyl-1-octanol 546.41
    1-chlorooctane 617.73
    1-chlorotetradecane 220.47
    n-nonane 199.5
    undecane 133.32
    tert-butylcyclohexane 208.99
    cyclooctane 161.08
    cyclopentanol 1716.18
    tetrahydropyran 4515.59
    tert-amyl methyl ether 1272.92
    2,5,8-trioxanonane 712.72
    1-hexene 1588.21
    2-isopropoxyethanol 824.61
    2,2,2-trifluoroethanol 218.79
    methyl butyrate 1210.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Seafennel (Turkey) 2 89997-98-8 Crithmum maritimum L., fam. Apiaceae (Umbelliferae) 0.3%