2-Isopropyl-3,5,6-trimethylpyrazine

Overview IFRA Botanical Request a quote

  • Identifiers

    Molecular formula
    C10H16N2

    SMILES
    CC1=C(N=C(C(=N1)C)C(C)C)C

  • Odor profile

    Nutty 63.14%
    Roasted 59.43%
    Earthy 58.67%
    Burnt 55.46%
    Cocoa 49.32%
    Musty 48.8%
    Coffee 46.24%
    Hazelnut 45.23%
    Chocolate 42.62%
    Potato 38.92%

    Scent© AI

  • Properties

    XLogP3-AA
    2.1

    Molecular weight
    164.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    224°C

    Flash point est.
    80.84 ˚C

  • Synonyms

    • 2-isopropyl-3,5,6-trimethylpyrazine
    • 104638-10-0
    • Pyrazine, trimethyl(1-methylethyl)- (9CI)
    • 2,3,5-trimethyl-6-propan-2-ylpyrazine
    • SCHEMBL2600737

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 611.22
    methanol 643.42
    isopropanol 525.99
    water 2.94
    ethyl acetate 852.46
    n-propanol 679.24
    acetone 869.67
    n-butanol 643.09
    acetonitrile 628.53
    DMF 1019.23
    toluene 909.65
    isobutanol 577.44
    1,4-dioxane 1405.18
    methyl acetate 789.46
    THF 2082.73
    2-butanone 905.3
    n-pentanol 501.18
    sec-butanol 645.38
    n-hexane 558.6
    ethylene glycol 105.63
    NMP 1289.79
    cyclohexane 739.54
    DMSO 644.43
    n-butyl acetate 1118.6
    n-octanol 540.84
    chloroform 3691.95
    n-propyl acetate 640.78
    acetic acid 469.99
    dichloromethane 3191.06
    cyclohexanone 1583.65
    propylene glycol 164.13
    isopropyl acetate 557.0
    DMAc 921.08
    2-ethoxyethanol 427.89
    isopentanol 521.67
    n-heptane 482.99
    ethyl formate 665.08
    1,2-dichloroethane 1617.23
    n-hexanol 827.2
    2-methoxyethanol 638.24
    isobutyl acetate 485.07
    tetrachloromethane 1085.82
    n-pentyl acetate 702.97
    transcutol 721.18
    n-heptanol 465.39
    ethylbenzene 639.72
    MIBK 503.76
    2-propoxyethanol 742.55
    tert-butanol 552.7
    MTBE 793.32
    2-butoxyethanol 472.35
    propionic acid 496.02
    o-xylene 675.57
    formic acid 136.31
    diethyl ether 1039.3
    m-xylene 662.64
    p-xylene 954.11
    chlorobenzene 1152.38
    dimethyl carbonate 370.3
    n-octane 228.89
    formamide 174.93
    cyclopentanone 1646.32
    2-pentanone 768.02
    anisole 659.81
    cyclopentyl methyl ether 1202.73
    gamma-butyrolactone 1687.03
    1-methoxy-2-propanol 497.65
    pyridine 1233.05
    3-pentanone 780.04
    furfural 1325.17
    n-dodecane 156.51
    diethylene glycol 339.49
    diisopropyl ether 402.56
    tert-amyl alcohol 608.21
    acetylacetone 746.1
    n-hexadecane 180.54
    acetophenone 599.71
    methyl propionate 710.38
    isopentyl acetate 902.86
    trichloroethylene 2723.42
    n-nonanol 438.21
    cyclohexanol 831.87
    benzyl alcohol 465.94
    2-ethylhexanol 612.94
    isooctanol 370.05
    dipropyl ether 853.13
    1,2-dichlorobenzene 1063.84
    ethyl lactate 269.78
    propylene carbonate 1077.5
    n-methylformamide 500.61
    2-pentanol 496.44
    n-pentane 426.59
    1-propoxy-2-propanol 578.37
    1-methoxy-2-propyl acetate 639.26
    2-(2-methoxypropoxy) propanol 343.36
    mesitylene 500.09
    ε-caprolactone 1236.9
    p-cymene 538.62
    epichlorohydrin 1606.21
    1,1,1-trichloroethane 1879.46
    2-aminoethanol 217.74
    morpholine-4-carbaldehyde 1031.84
    sulfolane 1485.85
    2,2,4-trimethylpentane 215.33
    2-methyltetrahydrofuran 1567.26
    n-hexyl acetate 923.13
    isooctane 143.11
    2-(2-butoxyethoxy)ethanol 421.21
    sec-butyl acetate 434.95
    tert-butyl acetate 549.59
    decalin 335.33
    glycerin 173.43
    diglyme 814.89
    acrylic acid 401.66
    isopropyl myristate 374.67
    n-butyric acid 700.5
    acetyl acetate 581.0
    di(2-ethylhexyl) phthalate 303.99
    ethyl propionate 607.55
    nitromethane 696.5
    1,2-diethoxyethane 693.47
    benzonitrile 804.15
    trioctyl phosphate 271.83
    1-bromopropane 1278.13
    gamma-valerolactone 1525.58
    n-decanol 329.01
    triethyl phosphate 362.71
    4-methyl-2-pentanol 284.09
    propionitrile 692.5
    vinylene carbonate 1069.89
    1,1,2-trichlorotrifluoroethane 791.95
    DMS 624.23
    cumene 483.46
    2-octanol 431.37
    2-hexanone 689.19
    octyl acetate 474.76
    limonene 707.06
    1,2-dimethoxyethane 944.4
    ethyl orthosilicate 348.54
    tributyl phosphate 318.0
    diacetone alcohol 402.41
    N,N-dimethylaniline 550.73
    acrylonitrile 693.77
    aniline 642.51
    1,3-propanediol 355.69
    bromobenzene 1442.32
    dibromomethane 2336.88
    1,1,2,2-tetrachloroethane 2247.16
    2-methyl-cyclohexyl acetate 565.91
    tetrabutyl urea 378.66
    diisobutyl methanol 312.81
    2-phenylethanol 582.48
    styrene 680.33
    dioctyl adipate 438.92
    dimethyl sulfate 478.21
    ethyl butyrate 716.62
    methyl lactate 265.57
    butyl lactate 411.3
    diethyl carbonate 519.09
    propanediol butyl ether 362.49
    triethyl orthoformate 521.02
    p-tert-butyltoluene 502.54
    methyl 4-tert-butylbenzoate 526.09
    morpholine 1219.11
    tert-butylamine 490.28
    n-dodecanol 266.82
    dimethoxymethane 834.76
    ethylene carbonate 903.92
    cyrene 386.42
    2-ethoxyethyl acetate 645.46
    2-ethylhexyl acetate 847.87
    1,2,4-trichlorobenzene 1111.14
    4-methylpyridine 1333.34
    dibutyl ether 749.96
    2,6-dimethyl-4-heptanol 312.81
    DEF 855.53
    dimethyl isosorbide 724.39
    tetrachloroethylene 1687.42
    eugenol 418.79
    triacetin 533.58
    span 80 389.37
    1,4-butanediol 192.64
    1,1-dichloroethane 1671.72
    2-methyl-1-pentanol 465.2
    methyl formate 518.19
    2-methyl-1-butanol 580.27
    n-decane 257.95
    butyronitrile 835.42
    3,7-dimethyl-1-octanol 438.41
    1-chlorooctane 641.57
    1-chlorotetradecane 268.24
    n-nonane 293.64
    undecane 195.36
    tert-butylcyclohexane 298.91
    cyclooctane 332.1
    cyclopentanol 876.54
    tetrahydropyran 1624.61
    tert-amyl methyl ether 717.79
    2,5,8-trioxanonane 522.91
    1-hexene 906.53
    2-isopropoxyethanol 342.33
    2,2,2-trifluoroethanol 218.89
    methyl butyrate 772.37

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Chicory root, roasted 2 68650-43-1 Cichorium intybus L., fam. Asteraceae (Compositae) 0.15%