Molecular formula
C8H13NS

SMILES
CC1=CN=C(S1)CC(C)C

Fragrance
Green	91.05%
Fruity	66.27%
Vegetable	64.53%
Tropical	53.22%
Nutty	53.07%
Earthy	45.35%
Roasted	40.05%
Leafy	36.93%
Meaty	36.36%
Tomato	35.69%

 

Flavor
Green	67.74%
Earthy	50.42%
Roasted	45.52%
Vegetable	41.71%
Burnt	35.74%
Earth	34.83%
Pepper	33.7%
Pea	29.01%
Tomato	28.16%
Metallic	27.75%

 

Odor impact est.
High

XLogP3-AA
3.0

pKa est.
6.32 (neutral)

Molecular weight
155.26 g/mol

Vapor pressure est.

• hPa @ 20°C
• hPa @ 25°C

Evaporation rate
Moderate

Boiling point est.
220°C

Flash point

• 66.33 ˚C est.

• 2-Isobutyl-5-methylthiazole
• Thiazole, 5-methyl-2-(2-methylpropyl)-
• 5-methyl-2-(2-methylpropyl)-1,3-thiazole
• SCHEMBL2629266
• SOWKBUUNEGNLMS-UHFFFAOYSA-
• SOWKBUUNEGNLMS-UHFFFAOYSA-N
• AKOS006275683
• 2-Isobutyl-5-methyl-1,3-thiazole #
• NS00113884
• InChI=1/C8H13NS/c1-6(2)4-8-9-5-7(3)10-8/h5-6H,4H2,1-3H3

2-Isobutyl-5-methylthiazole is primarily used as a flavor and fragrance ingredient, imparting roasted, nutty, and meaty notes that support flavor formulations (meat, coffee, and cereal profiles) and functioning as an odorant in perfumery. It may be incorporated into cosmetics and personal care products as a fragrance component, within regulatory and formulation limits. In industrial manufacturing, it acts as a synthetic intermediate for the preparation of other thiazole-containing compounds and related chemistries, supporting pharmaceutical and agrochemical R&D. It may also serve as a building block for the development of polymeric materials or specialty substrates. All uses are subject to local regulations and formulation constraints.

gpt-5-nano

Solvent	Solubility (g/L)
ethanol	167.53
methanol	132.98
isopropanol	187.72
water	0.83
ethyl acetate	203.21
n-propanol	188.92
acetone	329.48
n-butanol	215.33
acetonitrile	180.19
DMF	380.65
toluene	283.13
isobutanol	200.1
1,4-dioxane	430.38
methyl acetate	203.17
THF	804.08
2-butanone	276.26
n-pentanol	193.43
sec-butanol	204.22
n-hexane	94.37
ethylene glycol	48.57
NMP	540.37
cyclohexane	183.49
DMSO	301.48
n-butyl acetate	365.5
n-octanol	250.74
chloroform	874.52
n-propyl acetate	190.1
acetic acid	220.04
dichloromethane	561.75
cyclohexanone	606.7
propylene glycol	109.97
isopropyl acetate	175.56
DMAc	314.8
2-ethoxyethanol	159.58
isopentanol	214.73
n-heptane	163.38
ethyl formate	165.82
1,2-dichloroethane	311.05
n-hexanol	438.81
2-methoxyethanol	207.07
isobutyl acetate	186.75
tetrachloromethane	189.04
n-pentyl acetate	218.93
transcutol	440.31
n-heptanol	216.25
ethylbenzene	176.56
MIBK	212.14
2-propoxyethanol	395.84
tert-butanol	274.2
MTBE	257.78
2-butoxyethanol	235.23
propionic acid	190.73
o-xylene	207.1
formic acid	38.74
diethyl ether	198.09
m-xylene	228.76
p-xylene	239.9
chlorobenzene	335.34
dimethyl carbonate	109.05
n-octane	62.17
formamide	45.3
cyclopentanone	630.38
2-pentanone	268.11
anisole	253.14
cyclopentyl methyl ether	428.97
gamma-butyrolactone	514.19
1-methoxy-2-propanol	227.43
pyridine	386.68
3-pentanone	218.96
furfural	491.03
n-dodecane	59.98
diethylene glycol	226.11
diisopropyl ether	120.67
tert-amyl alcohol	248.5
acetylacetone	277.32
n-hexadecane	68.3
acetophenone	262.56
methyl propionate	185.38
isopentyl acetate	353.69
trichloroethylene	647.0
n-nonanol	217.21
cyclohexanol	350.71
benzyl alcohol	229.78
2-ethylhexanol	304.56
isooctanol	183.65
dipropyl ether	272.4
1,2-dichlorobenzene	310.12
ethyl lactate	137.07
propylene carbonate	417.38
n-methylformamide	132.12
2-pentanol	182.94
n-pentane	88.13
1-propoxy-2-propanol	348.91
1-methoxy-2-propyl acetate	302.16
2-(2-methoxypropoxy) propanol	264.76
mesitylene	177.6
ε-caprolactone	463.76
p-cymene	201.32
epichlorohydrin	472.98
1,1,1-trichloroethane	455.17
2-aminoethanol	100.52
morpholine-4-carbaldehyde	451.47
sulfolane	690.9
2,2,4-trimethylpentane	66.37
2-methyltetrahydrofuran	575.25
n-hexyl acetate	352.84
isooctane	54.04
2-(2-butoxyethoxy)ethanol	310.94
sec-butyl acetate	159.19
tert-butyl acetate	237.89
decalin	106.09
glycerin	124.87
diglyme	428.26
acrylic acid	171.64
isopropyl myristate	193.62
n-butyric acid	279.92
acetyl acetate	172.63
di(2-ethylhexyl) phthalate	199.9
ethyl propionate	159.12
nitromethane	248.71
1,2-diethoxyethane	233.63
benzonitrile	331.06
trioctyl phosphate	154.21
1-bromopropane	276.45
gamma-valerolactone	584.45
n-decanol	179.66
triethyl phosphate	153.45
4-methyl-2-pentanol	137.5
propionitrile	190.03
vinylene carbonate	359.17
1,1,2-trichlorotrifluoroethane	371.05
DMS	212.56
cumene	146.03
2-octanol	183.88
2-hexanone	250.48
octyl acetate	240.36
limonene	313.61
1,2-dimethoxyethane	304.18
ethyl orthosilicate	153.02
tributyl phosphate	170.79
diacetone alcohol	261.52
N,N-dimethylaniline	207.68
acrylonitrile	191.7
aniline	243.79
1,3-propanediol	136.59
bromobenzene	387.31
dibromomethane	450.68
1,1,2,2-tetrachloroethane	586.73
2-methyl-cyclohexyl acetate	310.75
tetrabutyl urea	221.47
diisobutyl methanol	177.8
2-phenylethanol	311.1
styrene	197.55
dioctyl adipate	248.03
dimethyl sulfate	163.38
ethyl butyrate	235.02
methyl lactate	138.17
butyl lactate	205.85
diethyl carbonate	174.82
propanediol butyl ether	273.33
triethyl orthoformate	198.74
p-tert-butyltoluene	209.18
methyl 4-tert-butylbenzoate	280.29
morpholine	437.23
tert-butylamine	219.22
n-dodecanol	155.49
dimethoxymethane	225.85
ethylene carbonate	291.37
cyrene	301.46
2-ethoxyethyl acetate	228.1
2-ethylhexyl acetate	308.33
1,2,4-trichlorobenzene	385.08
4-methylpyridine	451.68
dibutyl ether	232.46
2,6-dimethyl-4-heptanol	177.8
DEF	241.92
dimethyl isosorbide	464.0
tetrachloroethylene	364.93
eugenol	263.87
triacetin	279.56
span 80	334.31
1,4-butanediol	97.38
1,1-dichloroethane	371.08
2-methyl-1-pentanol	199.24
methyl formate	131.64
2-methyl-1-butanol	207.02
n-decane	87.58
butyronitrile	253.93
3,7-dimethyl-1-octanol	241.15
1-chlorooctane	211.54
1-chlorotetradecane	115.34
n-nonane	89.3
undecane	70.28
tert-butylcyclohexane	96.87
cyclooctane	89.24
cyclopentanol	364.74
tetrahydropyran	498.25
tert-amyl methyl ether	221.86
2,5,8-trioxanonane	359.69
1-hexene	195.81
2-isopropoxyethanol	164.55
2,2,2-trifluoroethanol	91.22
methyl butyrate	218.29

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