2-Imidazolidinone, 4,5-dihydroxy-

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  • Identifiers

    CAS number
    3720-97-6

    Molecular formula
    C3H6N2O3

    SMILES
    C1(C(NC(=O)N1)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 73.36%
    Sweet 30.22%
    Burnt 19.18%
    Fishy 17.43%
    Caramellic 16.28%
    Savory 16.26%
    Nutty 15.92%
    Bitter 14.53%
    Spicy 14.09%
    Popcorn 13.35%

     

    Flavor
    Bitter 62.6%
    Odorless 44.39%
    Sweet-like 23.82%
    Very mild 20.65%
    Alkaline 19.72%
    Rotten 19.68%
    Bland 19.65%
    Nitrile 19.4%
    Formyl 19.34%
    Cedarleaf 19.15%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.9

    pKa est.
    8.96 (weak base)

    Molecular weight
    118.09 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    489°C

    Flash point

    • 207.49 ˚C est.

  • Synonyms

    • 4,5-Dihydroxyimidazolidin-2-one
    • 3720-97-6
    • Dihydroxyethyleneurea
    • Glyoxalmonourein
    • Glyoxalmonoureine
    • 4,5-Dihydroxy-2-imidazolidinone
    • Acetylene monourein
    • 4,5-Dihydroxyethyleneurea
    • (1,2-Dihydroxyethylene)urea
    • 2-Imidazolidinone, 4,5-dihydroxy-
    • 4,5-Dihydroxyimidazolidone-2
    • 4,5-Dihydroxytetrahydroimidazol-2-one
    • EINECS 223-070-6
    • NSC 57542
    • DTXSID0052049
    • 4,5Dihydroxyethyleneurea
    • RefChem:473542
    • 4,5Dihydroxyimidazolidone2
    • (1,2Dihydroxyethylene)urea
    • 4,5Dihydroxyimidazolidin2one
    • 2Imidazolidinone, 4,5dihydroxy
    • DTXCID5030616
    • 4,5Dihydroxytetrahydroimidazol2one
    • 223-070-6
    • 4,5-dihydroxytetrahydro-2H-imidazol-2-one
    • Glyoxalurea
    • MFCD00186386
    • NSC57542
    • SCHEMBL30007
    • 2-Imidazolidinone,5-dihydroxy-
    • 4,5-dihydroxyimidazolidine-2-one
    • NSC-57542
    • STK042437
    • AKOS000487393
    • AKOS016339927
    • ST026461
    • DB-049080
    • CS-0317941
    • G85873
    • EN300-7278195
    • 11R-0058
    • 3720-97-6

  • Applications

    2-Imidazolidinone, 4,5-dihydroxy- (CAS 3720-97-6) is primarily used as an intermediate in organic synthesis and as a difunctional building block for specialty polymers and resin systems. The two hydroxyl groups enable it to act as a polyol or crosslinking site for polyurethane, epoxy, and other coatings formulations, after suitable derivatization. It can serve as a precursor to niche polymers and resin architectures used in industrial coatings, adhesives, and sealants. In formulation work, it may function as a chelating or complexing agent and as a reactive intermediate for further functionalization. Its use is typically as a chemical intermediate, with applications governed by process compatibility and regulatory requirements.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8.06
    methanol 28.67
    isopropanol 4.29
    water 763.11
    ethyl acetate 0.64
    n-propanol 4.3
    acetone 3.17
    n-butanol 2.81
    acetonitrile 1.8
    DMF 258.43
    toluene 0.21
    isobutanol 2.37
    1,4-dioxane 3.83
    methyl acetate 0.83
    THF 6.6
    2-butanone 1.34
    n-pentanol 1.33
    sec-butanol 2.41
    n-hexane 0.26
    ethylene glycol 56.14
    NMP 101.89
    cyclohexane 0.41
    DMSO 159.35
    n-butyl acetate 0.57
    n-octanol 0.65
    chloroform 0.37
    n-propyl acetate 0.48
    acetic acid 24.26
    dichloromethane 0.58
    cyclohexanone 3.25
    propylene glycol 31.26
    isopropyl acetate 0.53
    DMAc 82.73
    2-ethoxyethanol 11.8
    isopentanol 1.88
    n-heptane 0.42
    ethyl formate 2.69
    1,2-dichloroethane 0.55
    n-hexanol 1.2
    2-methoxyethanol 41.19
    isobutyl acetate 0.23
    tetrachloromethane 0.34
    n-pentyl acetate 0.53
    transcutol 6.52
    n-heptanol 1.23
    ethylbenzene 0.16
    MIBK 0.92
    2-propoxyethanol 7.45
    tert-butanol 4.03
    MTBE 0.72
    2-butoxyethanol 5.48
    propionic acid 6.46
    o-xylene 0.42
    formic acid 212.69
    diethyl ether 0.88
    m-xylene 0.31
    p-xylene 0.25
    chlorobenzene 0.11
    dimethyl carbonate 2.58
    n-octane 0.17
    formamide 169.01
    cyclopentanone 5.22
    2-pentanone 1.32
    anisole 0.34
    cyclopentyl methyl ether 2.25
    gamma-butyrolactone 8.66
    1-methoxy-2-propanol 19.09
    pyridine 1.82
    3-pentanone 1.12
    furfural 11.34
    n-dodecane 0.07
    diethylene glycol 19.91
    diisopropyl ether 0.33
    tert-amyl alcohol 2.7
    acetylacetone 1.85
    n-hexadecane 0.07
    acetophenone 0.74
    methyl propionate 1.6
    isopentyl acetate 0.51
    trichloroethylene 0.61
    n-nonanol 0.62
    cyclohexanol 2.49
    benzyl alcohol 0.98
    2-ethylhexanol 0.68
    isooctanol 0.85
    dipropyl ether 1.06
    1,2-dichlorobenzene 0.15
    ethyl lactate 2.41
    propylene carbonate 3.38
    n-methylformamide 68.1
    2-pentanol 1.43
    n-pentane 0.34
    1-propoxy-2-propanol 4.25
    1-methoxy-2-propyl acetate 1.44
    2-(2-methoxypropoxy) propanol 3.9
    mesitylene 0.29
    ε-caprolactone 3.12
    p-cymene 0.3
    epichlorohydrin 3.01
    1,1,1-trichloroethane 0.23
    2-aminoethanol 41.43
    morpholine-4-carbaldehyde 48.75
    sulfolane 31.36
    2,2,4-trimethylpentane 0.12
    2-methyltetrahydrofuran 2.21
    n-hexyl acetate 0.53
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 4.62
    sec-butyl acetate 0.28
    tert-butyl acetate 0.65
    decalin 0.11
    glycerin 88.51
    diglyme 9.67
    acrylic acid 13.27
    isopropyl myristate 0.26
    n-butyric acid 4.14
    acetyl acetate 0.54
    di(2-ethylhexyl) phthalate 0.63
    ethyl propionate 0.6
    nitromethane 21.66
    1,2-diethoxyethane 0.78
    benzonitrile 0.59
    trioctyl phosphate 0.61
    1-bromopropane 0.31
    gamma-valerolactone 14.92
    n-decanol 0.47
    triethyl phosphate 0.78
    4-methyl-2-pentanol 0.84
    propionitrile 1.11
    vinylene carbonate 3.23
    1,1,2-trichlorotrifluoroethane 14.03
    DMS 0.62
    cumene 0.18
    2-octanol 0.62
    2-hexanone 0.59
    octyl acetate 0.4
    limonene 0.46
    1,2-dimethoxyethane 10.45
    ethyl orthosilicate 0.68
    tributyl phosphate 0.58
    diacetone alcohol 3.52
    N,N-dimethylaniline 0.9
    acrylonitrile 2.43
    aniline 0.79
    1,3-propanediol 22.4
    bromobenzene 0.07
    dibromomethane 0.36
    1,1,2,2-tetrachloroethane 0.75
    2-methyl-cyclohexyl acetate 0.58
    tetrabutyl urea 1.36
    diisobutyl methanol 0.59
    2-phenylethanol 0.85
    styrene 0.14
    dioctyl adipate 0.49
    dimethyl sulfate 9.69
    ethyl butyrate 0.69
    methyl lactate 9.31
    butyl lactate 2.04
    diethyl carbonate 0.47
    propanediol butyl ether 6.4
    triethyl orthoformate 0.84
    p-tert-butyltoluene 0.3
    methyl 4-tert-butylbenzoate 1.78
    morpholine 8.25
    tert-butylamine 1.61
    n-dodecanol 0.36
    dimethoxymethane 16.02
    ethylene carbonate 2.21
    cyrene 8.57
    2-ethoxyethyl acetate 0.7
    2-ethylhexyl acetate 0.41
    1,2,4-trichlorobenzene 0.2
    4-methylpyridine 1.31
    dibutyl ether 0.38
    2,6-dimethyl-4-heptanol 0.59
    DEF 8.28
    dimethyl isosorbide 4.79
    tetrachloroethylene 0.79
    eugenol 2.84
    triacetin 0.97
    span 80 3.41
    1,4-butanediol 8.9
    1,1-dichloroethane 0.25
    2-methyl-1-pentanol 0.88
    methyl formate 25.69
    2-methyl-1-butanol 1.93
    n-decane 0.12
    butyronitrile 1.12
    3,7-dimethyl-1-octanol 0.47
    1-chlorooctane 0.16
    1-chlorotetradecane 0.08
    n-nonane 0.14
    undecane 0.09
    tert-butylcyclohexane 0.08
    cyclooctane 0.2
    cyclopentanol 4.36
    tetrahydropyran 1.8
    tert-amyl methyl ether 0.95
    2,5,8-trioxanonane 7.05
    1-hexene 0.34
    2-isopropoxyethanol 3.95
    2,2,2-trifluoroethanol 24.29
    methyl butyrate 1.08

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction