2-Hydroxytetracosanoic acid

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  • Identifiers

    CAS number
    544-57-0

    Molecular formula
    C24H48O3

    SMILES
    CCCCCCCCCCCCCCCCCCCCCCC(C(=O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 75.21%
    Fatty 61.49%
    Oily 38.23%
    Odorless 35.81%
    Creamy 21.88%
    Savory 19.83%
    Dairy 18.38%
    Milky 18.11%
    Sweet 17.59%
    Meaty 17.46%

     

    Flavor
    Waxy 45.67%
    Fatty 42.52%
    Mild 39.57%
    Bland 37.37%
    Odorless 32.41%
    Faint 31.81%
    Fat 27.07%
    Oily 25.06%
    Slightly waxy 24.55%
    Bay oil 22.64%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    10.7

    pKa est.
    7.21 (neutral)

    Molecular weight
    384.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    492°C

    Flash point

    • 230.05 ˚C est.

  • Synonyms

    • 2-Hydroxytetracosanoic acid
    • 544-57-0
    • Cerebronic acid
    • Phrenosinic acid
    • 2-hydroxylignoceric acid
    • 66QN3B074E
    • CHEBI:61302
    • DTXSID40969526
    • RefChem:909954
    • DTXCID601397076
    • DL-Cerebronic acid
    • Phrenosic acid
    • 2-hydroxy Lignoceric Acid
    • 2-hydroxy-tetracosanoic acid
    • Cerebronsaeure
    • acide cerebronique
    • a-hydroxylignoceric acid
    • 2-Hydroxy-tetracosansaeure
    • 2-hydroxytetraicosanoic acid
    • 2-hydroxytetraeicosanoic acid
    • alpha-hydroxytetracosanoic acid
    • SCHEMBL338278
    • UNII-66QN3B074E
    • orb1692229
    • Tetracosanoic acid, 2-hydroxy-
    • MSUOLNSQHLHDAS-UHFFFAOYSA-N
    • HY-N7811
    • LMFA01050080
    • MFCD00046527
    • .ALPHA.-HYDROXYLIGNOCERIC ACID
    • AKOS027379899
    • .ALPHA.-HYDROXYTETRACOSANOIC ACID
    • PD060508
    • DB-052577
    • C17873
    • Q11751627
    • 544-57-0

  • Applications

    2-Hydroxytetracosanoic acid (CAS 544-57-0) is a long-chain hydroxy fatty acid used as a versatile building block in industry. In polymers and plastics, it serves as a monomer or comonomer for specialty polyesters and polyurethanes and can be converted into esters or other derivatives for crosslinking and performance modifiers. In coatings, inks and related formulations, its waxy, hydrophobic tail and terminal hydroxyl enable use as a plasticizer or wax-like additive to adjust friction, gloss and rheology. In cosmetics and personal care, it can function as an emollient or starting material for surfactant or ester derivatives, contributing to moisturization and formulation stability. It is also evaluated for use in household cleaners and industrial cleaners as a surfactant or co-emulsifier, and may serve as an intermediate for bio-based surfactants or lubricant components in industrial manufacturing, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.93
    methanol 6.12
    isopropanol 3.87
    water 0.09
    ethyl acetate 18.59
    n-propanol 5.43
    acetone 13.6
    n-butanol 6.04
    acetonitrile 3.86
    DMF 35.64
    toluene 7.74
    isobutanol 5.25
    1,4-dioxane 26.76
    methyl acetate 14.01
    THF 102.19
    2-butanone 20.69
    n-pentanol 7.59
    sec-butanol 7.27
    n-hexane 4.22
    ethylene glycol 0.84
    NMP 142.67
    cyclohexane 16.62
    DMSO 75.14
    n-butyl acetate 36.21
    n-octanol 19.43
    chloroform 56.4
    n-propyl acetate 35.63
    acetic acid 11.4
    dichloromethane 55.45
    cyclohexanone 84.48
    propylene glycol 2.37
    isopropyl acetate 25.99
    DMAc 99.87
    2-ethoxyethanol 22.35
    isopentanol 9.34
    n-heptane 5.99
    ethyl formate 10.93
    1,2-dichloroethane 41.01
    n-hexanol 8.13
    2-methoxyethanol 18.71
    isobutyl acetate 27.03
    tetrachloromethane 22.26
    n-pentyl acetate 80.13
    transcutol 161.08
    n-heptanol 17.44
    ethylbenzene 10.75
    MIBK 27.99
    2-propoxyethanol 23.96
    tert-butanol 12.08
    MTBE 21.74
    2-butoxyethanol 47.01
    propionic acid 11.64
    o-xylene 12.46
    formic acid 4.12
    diethyl ether 11.44
    m-xylene 9.25
    p-xylene 15.13
    chlorobenzene 15.4
    dimethyl carbonate 10.5
    n-octane 4.57
    formamide 8.89
    cyclopentanone 90.34
    2-pentanone 21.64
    anisole 19.71
    cyclopentyl methyl ether 51.68
    gamma-butyrolactone 86.16
    1-methoxy-2-propanol 23.22
    pyridine 26.73
    3-pentanone 22.96
    furfural 56.79
    n-dodecane 2.26
    diethylene glycol 10.17
    diisopropyl ether 11.26
    tert-amyl alcohol 17.57
    acetylacetone 37.53
    n-hexadecane 2.67
    acetophenone 34.78
    methyl propionate 19.56
    isopentyl acetate 44.05
    trichloroethylene 73.56
    n-nonanol 20.78
    cyclohexanol 19.52
    benzyl alcohol 12.3
    2-ethylhexanol 13.46
    isooctanol 21.37
    dipropyl ether 26.84
    1,2-dichlorobenzene 27.35
    ethyl lactate 21.3
    propylene carbonate 52.89
    n-methylformamide 11.91
    2-pentanol 7.14
    n-pentane 2.38
    1-propoxy-2-propanol 33.48
    1-methoxy-2-propyl acetate 47.41
    2-(2-methoxypropoxy) propanol 48.7
    mesitylene 10.54
    ε-caprolactone 85.68
    p-cymene 13.65
    epichlorohydrin 70.44
    1,1,1-trichloroethane 51.91
    2-aminoethanol 2.93
    morpholine-4-carbaldehyde 72.8
    sulfolane 222.73
    2,2,4-trimethylpentane 5.06
    2-methyltetrahydrofuran 62.24
    n-hexyl acetate 70.07
    isooctane 2.81
    2-(2-butoxyethoxy)ethanol 64.91
    sec-butyl acetate 33.54
    tert-butyl acetate 54.2
    decalin 9.37
    glycerin 6.02
    diglyme 135.69
    acrylic acid 8.71
    isopropyl myristate 24.97
    n-butyric acid 23.47
    acetyl acetate 17.99
    di(2-ethylhexyl) phthalate 21.06
    ethyl propionate 32.66
    nitromethane 24.82
    1,2-diethoxyethane 57.72
    benzonitrile 13.87
    trioctyl phosphate 18.36
    1-bromopropane 21.63
    gamma-valerolactone 117.83
    n-decanol 12.7
    triethyl phosphate 35.71
    4-methyl-2-pentanol 8.57
    propionitrile 5.73
    vinylene carbonate 33.82
    1,1,2-trichlorotrifluoroethane 68.63
    DMS 33.18
    cumene 11.18
    2-octanol 19.17
    2-hexanone 29.68
    octyl acetate 29.65
    limonene 23.0
    1,2-dimethoxyethane 55.27
    ethyl orthosilicate 37.18
    tributyl phosphate 23.37
    diacetone alcohol 55.68
    N,N-dimethylaniline 23.05
    acrylonitrile 6.01
    aniline 8.92
    1,3-propanediol 6.05
    bromobenzene 18.51
    dibromomethane 36.82
    1,1,2,2-tetrachloroethane 89.03
    2-methyl-cyclohexyl acetate 50.28
    tetrabutyl urea 39.91
    diisobutyl methanol 15.47
    2-phenylethanol 13.87
    styrene 9.82
    dioctyl adipate 46.93
    dimethyl sulfate 35.7
    ethyl butyrate 44.03
    methyl lactate 15.45
    butyl lactate 57.6
    diethyl carbonate 25.29
    propanediol butyl ether 38.7
    triethyl orthoformate 48.25
    p-tert-butyltoluene 14.22
    methyl 4-tert-butylbenzoate 68.44
    morpholine 38.99
    tert-butylamine 9.48
    n-dodecanol 8.71
    dimethoxymethane 23.0
    ethylene carbonate 31.96
    cyrene 51.78
    2-ethoxyethyl acetate 73.69
    2-ethylhexyl acetate 39.38
    1,2,4-trichlorobenzene 35.19
    4-methylpyridine 22.44
    dibutyl ether 40.02
    2,6-dimethyl-4-heptanol 15.47
    DEF 40.77
    dimethyl isosorbide 112.43
    tetrachloroethylene 57.24
    eugenol 50.9
    triacetin 80.35
    span 80 46.63
    1,4-butanediol 3.55
    1,1-dichloroethane 27.86
    2-methyl-1-pentanol 11.66
    methyl formate 8.46
    2-methyl-1-butanol 8.96
    n-decane 5.59
    butyronitrile 7.42
    3,7-dimethyl-1-octanol 20.87
    1-chlorooctane 21.97
    1-chlorotetradecane 6.39
    n-nonane 5.39
    undecane 3.27
    tert-butylcyclohexane 7.29
    cyclooctane 6.24
    cyclopentanol 20.11
    tetrahydropyran 39.95
    tert-amyl methyl ether 27.87
    2,5,8-trioxanonane 82.28
    1-hexene 7.78
    2-isopropoxyethanol 20.9
    2,2,2-trifluoroethanol 10.01
    methyl butyrate 46.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction