2-Hydroxypropyl methacrylate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    923-26-2

    Molecular formula
    C7H12O3

    SMILES
    CC(COC(=O)C(=C)C)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Caramellic 55.51%
    Fruity 53.98%
    Sweet 46.82%
    Buttery 43.75%
    Ethereal 33.33%
    Creamy 31.7%
    Burnt 27.9%
    Nutty 27.74%
    Milky 27.26%
    Rummy 25.41%

     

    Flavor
    Fruity 69.76%
    Sweet 37.34%
    Creamy 33.57%
    Berry 30.4%
    Caramel 28.58%
    Buttery 25.66%
    Tropical 24.85%
    Grape 23.67%
    Butter 22.89%
    Musty 21.73%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    8.08 (weak base)

    Molecular weight
    144.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    202°C

    Flash point

    • 84.37 ˚C est.

  • Synonyms

    • 2-Hydroxypropyl methacrylate
    • 923-26-2
    • Acryester HP
    • beta-Hydroxypropyl methacrylate
    • 2-Hydroxypropyl 2-methyl-2-propenoate
    • 2-Propenoic acid, 2-methyl-, 2-hydroxypropyl ester
    • 2-HPMA
    • METHACRYLIC ACID, 2-HYDROXYPROPYL ESTER
    • V9B8S034AW
    • CHEBI:53440
    • BLEMMER P
    • RefChem:87608
    • GlyTouCan:G03618RH
    • G03618RH
    • 213-090-3
    • 2-Hydroxypropylmethacrylate
    • 2-hydroxypropyl 2-methylprop-2-enoate
    • 2-Hydroxypropyl 2-methylacrylate
    • methacrylic acid 2-hydroxypropyl ester
    • DTXSID1029629
    • 2HPMA
    • 2-hydroxy-n-propyl methacrylate
    • 2-hydroxy-3-propyl methacrylate
    • .beta.-hydroxypropyl methacrylate
    • DSSTox_CID_5934
    • EINECS 213-090-3
    • BRN 1752228
    • UNII-V9B8S034AW
    • Epitope ID:131322
    • DSSTox_RID_77971
    • DSSTox_RID_78619
    • DSSTox_GSID_25934
    • DSSTox_GSID_27936
    • SCHEMBL19017
    • SCHEMBL166150
    • SCHEMBL198125
    • DTXCID805934
    • CHEMBL1873783
    • SCHEMBL27697323
    • SCHEMBL28747006
    • 1,2-Propanediol, 1-methacrylate
    • 2-Hydroxypropyl 2-methylacrylate #
    • Tox21_200694
    • Tox21_201232
    • Tox21_202531
    • 2-Hydroxypropyl methacrylate (HPMA)
    • MFCD00004536
    • AKOS015899917
    • CS-W011008
    • NCGC00090806-01
    • NCGC00090806-02
    • NCGC00090806-03
    • NCGC00258248-01
    • NCGC00258784-01
    • NCGC00260080-01
    • AS-59279
    • CAS-923-26-2
    • CAS-25703-79-1
    • CAS-27813-02-1
    • M0512
    • NS00014926
    • Hydroxypropyl methacrylate, mixture of isomers
    • D93082
    • 2-Propenoic acid,2-methyl-,2-hydroxypropyl ester
    • Q27124054
    • 923-26-2

  • Applications

    2-Hydroxypropyl methacrylate (CAS 923-26-2) is a reactive monomer and functional intermediate widely used to synthesize water-compatible polyacrylates and hydrogel-forming polymers. In practice, it serves as a reactive diluent and hydroxyl-functional monomer for UV-curable coatings and inks, enabling improved crosslinking and surface adhesion. It is also employed in adhesive formulations and specialty resins where the pendant hydroxyl group allows post-polymerization modification. Additionally, it participates in hydrogel materials and polymer networks with swelling properties, and can be used as a modifier in resin systems to introduce hydroxyl functionality for coatings and related applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 655.55
    methanol 965.44
    isopropanol 422.91
    water 45.52
    ethyl acetate 105.98
    n-propanol 389.14
    acetone 263.47
    n-butanol 374.59
    acetonitrile 182.3
    DMF 465.82
    toluene 47.6
    isobutanol 269.43
    1,4-dioxane 393.33
    methyl acetate 148.59
    THF 388.96
    2-butanone 195.09
    n-pentanol 287.37
    sec-butanol 351.6
    n-hexane 20.04
    ethylene glycol 234.5
    NMP 314.61
    cyclohexane 26.62
    DMSO 450.62
    n-butyl acetate 134.26
    n-octanol 143.72
    chloroform 150.19
    n-propyl acetate 100.35
    acetic acid 393.54
    dichloromethane 212.91
    cyclohexanone 217.17
    propylene glycol 215.96
    isopropyl acetate 68.47
    DMAc 432.7
    2-ethoxyethanol 441.36
    isopentanol 293.42
    n-heptane 22.03
    ethyl formate 173.99
    1,2-dichloroethane 127.05
    n-hexanol 221.53
    2-methoxyethanol 627.0
    isobutyl acetate 64.33
    tetrachloromethane 21.48
    n-pentyl acetate 83.93
    transcutol 538.85
    n-heptanol 121.86
    ethylbenzene 55.43
    MIBK 100.99
    2-propoxyethanol 302.41
    tert-butanol 461.46
    MTBE 211.9
    2-butoxyethanol 206.34
    propionic acid 185.6
    o-xylene 56.81
    formic acid 343.16
    diethyl ether 164.84
    m-xylene 44.4
    p-xylene 74.35
    chlorobenzene 58.45
    dimethyl carbonate 46.21
    n-octane 11.28
    formamide 338.65
    cyclopentanone 217.24
    2-pentanone 156.47
    anisole 133.17
    cyclopentyl methyl ether 137.45
    gamma-butyrolactone 226.19
    1-methoxy-2-propanol 344.58
    pyridine 164.09
    3-pentanone 93.87
    furfural 254.38
    n-dodecane 11.94
    diethylene glycol 289.85
    diisopropyl ether 40.4
    tert-amyl alcohol 393.92
    acetylacetone 119.66
    n-hexadecane 12.31
    acetophenone 134.4
    methyl propionate 94.26
    isopentyl acetate 126.29
    trichloroethylene 170.86
    n-nonanol 116.75
    cyclohexanol 201.7
    benzyl alcohol 161.95
    2-ethylhexanol 131.38
    isooctanol 91.18
    dipropyl ether 96.32
    1,2-dichlorobenzene 57.05
    ethyl lactate 79.96
    propylene carbonate 143.44
    n-methylformamide 266.29
    2-pentanol 216.3
    n-pentane 24.74
    1-propoxy-2-propanol 205.07
    1-methoxy-2-propyl acetate 114.41
    2-(2-methoxypropoxy) propanol 199.8
    mesitylene 31.94
    ε-caprolactone 195.38
    p-cymene 46.14
    epichlorohydrin 256.79
    1,1,1-trichloroethane 60.61
    2-aminoethanol 358.13
    morpholine-4-carbaldehyde 393.11
    sulfolane 251.19
    2,2,4-trimethylpentane 17.6
    2-methyltetrahydrofuran 283.69
    n-hexyl acetate 136.46
    isooctane 11.11
    2-(2-butoxyethoxy)ethanol 256.94
    sec-butyl acetate 64.96
    tert-butyl acetate 89.6
    decalin 19.01
    glycerin 263.58
    diglyme 391.88
    acrylic acid 167.31
    isopropyl myristate 61.46
    n-butyric acid 221.88
    acetyl acetate 61.79
    di(2-ethylhexyl) phthalate 76.12
    ethyl propionate 78.1
    nitromethane 340.51
    1,2-diethoxyethane 176.95
    benzonitrile 116.93
    trioctyl phosphate 61.0
    1-bromopropane 84.57
    gamma-valerolactone 312.94
    n-decanol 91.31
    triethyl phosphate 55.87
    4-methyl-2-pentanol 110.0
    propionitrile 138.23
    vinylene carbonate 137.78
    1,1,2-trichlorotrifluoroethane 214.02
    DMS 71.73
    cumene 48.31
    2-octanol 81.46
    2-hexanone 138.4
    octyl acetate 87.12
    limonene 70.08
    1,2-dimethoxyethane 533.15
    ethyl orthosilicate 55.47
    tributyl phosphate 65.61
    diacetone alcohol 170.92
    N,N-dimethylaniline 119.82
    acrylonitrile 160.12
    aniline 104.62
    1,3-propanediol 419.61
    bromobenzene 44.41
    dibromomethane 127.84
    1,1,2,2-tetrachloroethane 148.82
    2-methyl-cyclohexyl acetate 102.47
    tetrabutyl urea 96.08
    diisobutyl methanol 73.83
    2-phenylethanol 131.46
    styrene 59.26
    dioctyl adipate 99.4
    dimethyl sulfate 73.07
    ethyl butyrate 103.82
    methyl lactate 87.49
    butyl lactate 92.4
    diethyl carbonate 67.35
    propanediol butyl ether 212.44
    triethyl orthoformate 75.82
    p-tert-butyltoluene 44.81
    methyl 4-tert-butylbenzoate 119.04
    morpholine 421.62
    tert-butylamine 279.37
    n-dodecanol 74.21
    dimethoxymethane 244.96
    ethylene carbonate 109.03
    cyrene 176.26
    2-ethoxyethyl acetate 111.49
    2-ethylhexyl acetate 95.5
    1,2,4-trichlorobenzene 75.19
    4-methylpyridine 170.44
    dibutyl ether 103.93
    2,6-dimethyl-4-heptanol 73.83
    DEF 204.67
    dimethyl isosorbide 226.42
    tetrachloroethylene 106.96
    eugenol 138.41
    triacetin 115.08
    span 80 163.04
    1,4-butanediol 238.32
    1,1-dichloroethane 94.55
    2-methyl-1-pentanol 245.63
    methyl formate 200.77
    2-methyl-1-butanol 274.28
    n-decane 16.89
    butyronitrile 179.85
    3,7-dimethyl-1-octanol 129.11
    1-chlorooctane 55.32
    1-chlorotetradecane 26.56
    n-nonane 15.9
    undecane 13.76
    tert-butylcyclohexane 18.72
    cyclooctane 11.0
    cyclopentanol 217.38
    tetrahydropyran 253.34
    tert-amyl methyl ether 179.66
    2,5,8-trioxanonane 303.04
    1-hexene 70.5
    2-isopropoxyethanol 263.87
    2,2,2-trifluoroethanol 119.59
    methyl butyrate 134.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction