2-Hydroxyhexacosanoic acid

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  • Identifiers

    CAS number
    14176-13-7

    Molecular formula
    C26H52O3

    SMILES
    CCCCCCCCCCCCCCCCCCCCCCCCC(C(=O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 76.37%
    Fatty 60.81%
    Oily 37.78%
    Odorless 35.76%
    Creamy 20.51%
    Savory 19.29%
    Fishy 17.04%
    Meaty 16.99%
    Dairy 16.95%
    Sweet 16.75%

     

    Flavor
    Waxy 45.81%
    Fatty 40.81%
    Mild 39.15%
    Bland 37.48%
    Faint 31.66%
    Odorless 31.54%
    Fat 26.18%
    Slightly waxy 24.41%
    Oily 24.09%
    Bay oil 22.36%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    11.8

    pKa est.
    7.53 (neutral)

    Molecular weight
    412.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    540°C

    Flash point

    • 241.4 ˚C est.

  • Synonyms

    • 2-Hydroxyhexacosanoic acid
    • 14176-13-7
    • 2-hydroxy-hexacosanoic acid
    • 2-hydroxycerotic acid
    • Hexacosanoic acid, 2-hydroxy-
    • EINECS 238-029-8
    • alpha-hydroxycerotic acid
    • alpha-hydroxyhexacosanoic acid
    • SCHEMBL337352
    • CHEBI:76986
    • DTXSID60931189
    • IFYDZTDBJZWEPK-UHFFFAOYSA-N
    • LMFA01050218
    • NS00052694
    • Q27146499
    • 14176-13-7

  • Applications

    2-Hydroxyhexacosanoic acid (CAS 14176-13-7) is a long-chain alpha-hydroxy fatty acid that functions as a versatile building block in polymer and formulation chemistry. In industrial manufacturing it is used as a monomer or chain extender for specialty polyesters and polyurethane polyols, aiding coatings, adhesives, and high-performance plastics, while its hydroxyl group enables esterification to make lubricants or internal plasticizers for polymer systems. In coatings and inks, it serves as a raw material for polyester resins and related UV-curable systems. It can be derivatized to prepare cosmetic esters and conditioning ingredients for personal care, and may be employed as a surfactant or emulsifier in cleaning and household formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.65
    methanol 5.71
    isopropanol 3.47
    water 0.12
    ethyl acetate 18.59
    n-propanol 5.09
    acetone 13.5
    n-butanol 5.51
    acetonitrile 3.88
    DMF 33.73
    toluene 7.8
    isobutanol 4.93
    1,4-dioxane 26.62
    methyl acetate 13.76
    THF 94.72
    2-butanone 20.5
    n-pentanol 7.0
    sec-butanol 6.83
    n-hexane 4.29
    ethylene glycol 0.81
    NMP 140.72
    cyclohexane 17.05
    DMSO 69.0
    n-butyl acetate 34.59
    n-octanol 18.52
    chloroform 57.98
    n-propyl acetate 34.16
    acetic acid 11.34
    dichloromethane 56.09
    cyclohexanone 82.15
    propylene glycol 2.17
    isopropyl acetate 25.68
    DMAc 97.26
    2-ethoxyethanol 20.66
    isopentanol 8.35
    n-heptane 6.1
    ethyl formate 10.85
    1,2-dichloroethane 40.39
    n-hexanol 7.31
    2-methoxyethanol 17.16
    isobutyl acetate 26.13
    tetrachloromethane 23.29
    n-pentyl acetate 78.84
    transcutol 147.86
    n-heptanol 16.58
    ethylbenzene 10.64
    MIBK 26.94
    2-propoxyethanol 21.78
    tert-butanol 10.48
    MTBE 20.53
    2-butoxyethanol 44.6
    propionic acid 11.21
    o-xylene 12.61
    formic acid 4.21
    diethyl ether 10.97
    m-xylene 9.11
    p-xylene 15.09
    chlorobenzene 15.28
    dimethyl carbonate 10.83
    n-octane 4.69
    formamide 8.83
    cyclopentanone 86.22
    2-pentanone 20.98
    anisole 19.12
    cyclopentyl methyl ether 49.65
    gamma-butyrolactone 83.92
    1-methoxy-2-propanol 21.1
    pyridine 26.57
    3-pentanone 23.26
    furfural 55.65
    n-dodecane 2.28
    diethylene glycol 9.35
    diisopropyl ether 10.87
    tert-amyl alcohol 16.12
    acetylacetone 37.05
    n-hexadecane 2.67
    acetophenone 34.14
    methyl propionate 19.76
    isopentyl acetate 42.62
    trichloroethylene 72.22
    n-nonanol 19.93
    cyclohexanol 18.23
    benzyl alcohol 11.52
    2-ethylhexanol 12.68
    isooctanol 20.41
    dipropyl ether 26.37
    1,2-dichlorobenzene 27.16
    ethyl lactate 20.63
    propylene carbonate 52.87
    n-methylformamide 11.52
    2-pentanol 6.52
    n-pentane 2.43
    1-propoxy-2-propanol 31.08
    1-methoxy-2-propyl acetate 46.44
    2-(2-methoxypropoxy) propanol 46.63
    mesitylene 10.27
    ε-caprolactone 85.28
    p-cymene 13.56
    epichlorohydrin 68.52
    1,1,1-trichloroethane 53.14
    2-aminoethanol 2.74
    morpholine-4-carbaldehyde 70.19
    sulfolane 216.78
    2,2,4-trimethylpentane 5.1
    2-methyltetrahydrofuran 58.89
    n-hexyl acetate 68.94
    isooctane 2.71
    2-(2-butoxyethoxy)ethanol 61.52
    sec-butyl acetate 32.83
    tert-butyl acetate 52.64
    decalin 9.5
    glycerin 5.6
    diglyme 129.53
    acrylic acid 8.52
    isopropyl myristate 24.58
    n-butyric acid 22.64
    acetyl acetate 18.08
    di(2-ethylhexyl) phthalate 20.82
    ethyl propionate 32.38
    nitromethane 24.27
    1,2-diethoxyethane 55.3
    benzonitrile 13.23
    trioctyl phosphate 17.98
    1-bromopropane 21.48
    gamma-valerolactone 112.95
    n-decanol 12.16
    triethyl phosphate 36.26
    4-methyl-2-pentanol 7.79
    propionitrile 5.61
    vinylene carbonate 34.56
    1,1,2-trichlorotrifluoroethane 66.79
    DMS 33.12
    cumene 11.0
    2-octanol 18.62
    2-hexanone 28.82
    octyl acetate 29.3
    limonene 22.68
    1,2-dimethoxyethane 51.91
    ethyl orthosilicate 37.73
    tributyl phosphate 23.02
    diacetone alcohol 52.29
    N,N-dimethylaniline 22.56
    acrylonitrile 5.85
    aniline 8.59
    1,3-propanediol 5.52
    bromobenzene 18.7
    dibromomethane 37.46
    1,1,2,2-tetrachloroethane 87.54
    2-methyl-cyclohexyl acetate 49.54
    tetrabutyl urea 39.28
    diisobutyl methanol 14.7
    2-phenylethanol 13.02
    styrene 9.65
    dioctyl adipate 46.62
    dimethyl sulfate 36.78
    ethyl butyrate 43.52
    methyl lactate 15.13
    butyl lactate 56.32
    diethyl carbonate 25.33
    propanediol butyl ether 36.41
    triethyl orthoformate 48.46
    p-tert-butyltoluene 14.02
    methyl 4-tert-butylbenzoate 68.3
    morpholine 37.33
    tert-butylamine 8.3
    n-dodecanol 8.32
    dimethoxymethane 22.07
    ethylene carbonate 32.59
    cyrene 49.27
    2-ethoxyethyl acetate 73.09
    2-ethylhexyl acetate 38.37
    1,2,4-trichlorobenzene 35.28
    4-methylpyridine 21.93
    dibutyl ether 38.91
    2,6-dimethyl-4-heptanol 14.7
    DEF 39.44
    dimethyl isosorbide 109.55
    tetrachloroethylene 57.48
    eugenol 49.77
    triacetin 79.96
    span 80 44.96
    1,4-butanediol 3.27
    1,1-dichloroethane 28.03
    2-methyl-1-pentanol 10.73
    methyl formate 8.45
    2-methyl-1-butanol 8.25
    n-decane 5.66
    butyronitrile 7.06
    3,7-dimethyl-1-octanol 19.74
    1-chlorooctane 21.7
    1-chlorotetradecane 6.38
    n-nonane 5.51
    undecane 3.3
    tert-butylcyclohexane 7.24
    cyclooctane 6.51
    cyclopentanol 18.5
    tetrahydropyran 38.97
    tert-amyl methyl ether 26.66
    2,5,8-trioxanonane 78.2
    1-hexene 7.61
    2-isopropoxyethanol 19.24
    2,2,2-trifluoroethanol 10.14
    methyl butyrate 44.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction