(((2-hydroxyethyl)imino)dimethylene)bisphosphonic acid, sodium salt

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  • Identifiers

    CAS number
    22036-78-8

    Molecular formula
    C4H13NNaO7P2+

    SMILES
    C(CO)N(CP(=O)(O)O)CP(=O)(O)O.[Na+]

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 70.3%
    Sweet 32.87%
    Savory 18.72%
    Clean 17.9%
    Fishy 16.35%
    Alcoholic 16.3%
    Bitter 14.5%
    Oily 13.79%
    Sour 13.35%
    Cooling 12.98%

     

    Flavor
    Odorless 73.18%
    Mild 33.63%
    Bland 28.98%
    Sour 26.01%
    Very mild 23.7%
    Yeast 22.58%
    Sweet-like 22.43%
    Faint 21.25%
    Formyl 19.7%
    Soy 19.69%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.97 (weak acid)

    Molecular weight
    272.09 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1332°C

    Flash point

    • 322.15 ˚C est.

  • Synonyms

    • EINECS 244-743-0
    • (((2-Hydroxyethyl)imino)dimethylene)bisphosphonic acid, sodium salt
    • 22036-78-8
    • [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt
    • RefChem:67062
    • 244-743-0
    • TZMFSKGQNJCLEU-UHFFFAOYSA-N
    • 22036-78-8

  • Applications

    Applications of the disodium salt of (((2-hydroxyethyl)imino)dimethylene)bisphosphonic acid, CAS 22036-78-8 include industrial water treatment, detergents and cleaners, paper and process water conditioning, metal finishing and surface treatment, and polymer or plastics processing. It is commonly used as a scale inhibitor and corrosion inhibitor in cooling water and boiler systems; as a chelating and dispersing agent in household and industrial detergents and cleaners; as a process water conditioner in papermaking and related process waters to reduce scaling and metal ion precipitation; as a chelating agent and corrosion inhibitor in metal finishing and pretreatment for plating; and as a processing aid or stabilizer in plastics and polymer manufacture to control metal-catalyst activity and minimize precipitation during processing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.46
    methanol 1.09
    isopropanol 0.36
    water 38.17
    ethyl acetate 0.42
    n-propanol 0.48
    acetone 0.54
    n-butanol 0.43
    acetonitrile 0.37
    DMF 10.34
    toluene 0.41
    isobutanol 0.34
    1,4-dioxane 0.61
    methyl acetate 0.25
    THF 1.49
    2-butanone 0.37
    n-pentanol 0.3
    sec-butanol 0.34
    n-hexane 0.11
    ethylene glycol 5.94
    NMP 31.64
    cyclohexane 0.24
    DMSO 15.33
    n-butyl acetate 0.62
    n-octanol 0.37
    chloroform 0.07
    n-propyl acetate 0.26
    acetic acid 1.99
    dichloromethane 0.15
    cyclohexanone 1.49
    propylene glycol 3.81
    isopropyl acetate 0.35
    DMAc 8.38
    2-ethoxyethanol 1.95
    isopentanol 0.36
    n-heptane 0.45
    ethyl formate 0.48
    1,2-dichloroethane 0.21
    n-hexanol 1.0
    2-methoxyethanol 5.33
    isobutyl acetate 0.14
    tetrachloromethane 0.05
    n-pentyl acetate 0.37
    transcutol 3.02
    n-heptanol 0.8
    ethylbenzene 0.21
    MIBK 0.38
    2-propoxyethanol 5.45
    tert-butanol 0.42
    MTBE 0.14
    2-butoxyethanol 2.8
    propionic acid 1.08
    o-xylene 0.64
    formic acid 12.96
    diethyl ether 0.22
    m-xylene 0.56
    p-xylene 0.22
    chlorobenzene 0.13
    dimethyl carbonate 1.13
    n-octane 0.12
    formamide 12.21
    cyclopentanone 2.31
    2-pentanone 0.52
    anisole 0.26
    cyclopentyl methyl ether 1.37
    gamma-butyrolactone 3.62
    1-methoxy-2-propanol 4.73
    pyridine 0.85
    3-pentanone 0.55
    furfural 5.26
    n-dodecane 0.05
    diethylene glycol 12.15
    diisopropyl ether 0.17
    tert-amyl alcohol 0.41
    acetylacetone 1.01
    n-hexadecane 0.06
    acetophenone 0.67
    methyl propionate 0.9
    isopentyl acetate 0.44
    trichloroethylene 0.21
    n-nonanol 0.37
    cyclohexanol 0.95
    benzyl alcohol 0.59
    2-ethylhexanol 0.6
    isooctanol 0.48
    dipropyl ether 0.81
    1,2-dichlorobenzene 0.17
    ethyl lactate 1.29
    propylene carbonate 1.46
    n-methylformamide 4.06
    2-pentanol 0.38
    n-pentane 0.13
    1-propoxy-2-propanol 3.77
    1-methoxy-2-propyl acetate 1.75
    2-(2-methoxypropoxy) propanol 1.84
    mesitylene 0.46
    ε-caprolactone 1.59
    p-cymene 0.55
    epichlorohydrin 0.91
    1,1,1-trichloroethane 0.06
    2-aminoethanol 4.81
    morpholine-4-carbaldehyde 12.92
    sulfolane 16.03
    2,2,4-trimethylpentane 0.06
    2-methyltetrahydrofuran 0.64
    n-hexyl acetate 0.35
    isooctane 0.04
    2-(2-butoxyethoxy)ethanol 2.39
    sec-butyl acetate 0.19
    tert-butyl acetate 0.38
    decalin 0.1
    glycerin 23.93
    diglyme 3.37
    acrylic acid 2.31
    isopropyl myristate 0.17
    n-butyric acid 1.12
    acetyl acetate 0.33
    di(2-ethylhexyl) phthalate 0.35
    ethyl propionate 0.41
    nitromethane 2.13
    1,2-diethoxyethane 0.41
    benzonitrile 0.38
    trioctyl phosphate 0.37
    1-bromopropane 0.12
    gamma-valerolactone 5.25
    n-decanol 0.29
    triethyl phosphate 0.66
    4-methyl-2-pentanol 0.27
    propionitrile 0.3
    vinylene carbonate 1.32
    1,1,2-trichlorotrifluoroethane 3.9
    DMS 0.52
    cumene 0.2
    2-octanol 0.36
    2-hexanone 0.25
    octyl acetate 0.24
    limonene 0.71
    1,2-dimethoxyethane 1.19
    ethyl orthosilicate 0.61
    tributyl phosphate 0.32
    diacetone alcohol 1.49
    N,N-dimethylaniline 0.67
    acrylonitrile 0.65
    aniline 0.82
    1,3-propanediol 2.42
    bromobenzene 0.11
    dibromomethane 0.11
    1,1,2,2-tetrachloroethane 0.28
    2-methyl-cyclohexyl acetate 0.58
    tetrabutyl urea 0.82
    diisobutyl methanol 0.48
    2-phenylethanol 1.01
    styrene 0.16
    dioctyl adipate 0.27
    dimethyl sulfate 3.93
    ethyl butyrate 0.63
    methyl lactate 4.23
    butyl lactate 1.36
    diethyl carbonate 0.36
    propanediol butyl ether 2.78
    triethyl orthoformate 0.7
    p-tert-butyltoluene 0.56
    methyl 4-tert-butylbenzoate 1.43
    morpholine 1.24
    tert-butylamine 0.28
    n-dodecanol 0.22
    dimethoxymethane 2.61
    ethylene carbonate 0.95
    cyrene 5.52
    2-ethoxyethyl acetate 0.51
    2-ethylhexyl acetate 0.4
    1,2,4-trichlorobenzene 0.22
    4-methylpyridine 0.74
    dibutyl ether 0.2
    2,6-dimethyl-4-heptanol 0.48
    DEF 2.2
    dimethyl isosorbide 4.19
    tetrachloroethylene 0.26
    eugenol 2.02
    triacetin 0.67
    span 80 2.13
    1,4-butanediol 1.11
    1,1-dichloroethane 0.07
    2-methyl-1-pentanol 0.23
    methyl formate 2.01
    2-methyl-1-butanol 0.39
    n-decane 0.1
    butyronitrile 0.27
    3,7-dimethyl-1-octanol 0.27
    1-chlorooctane 0.13
    1-chlorotetradecane 0.07
    n-nonane 0.1
    undecane 0.07
    tert-butylcyclohexane 0.07
    cyclooctane 0.23
    cyclopentanol 1.14
    tetrahydropyran 0.38
    tert-amyl methyl ether 0.28
    2,5,8-trioxanonane 2.87
    1-hexene 0.12
    2-isopropoxyethanol 0.95
    2,2,2-trifluoroethanol 2.34
    methyl butyrate 0.48

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction