2-Hydroxyethyl hexadecanoate

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  • Identifiers

    CAS number
    4219-49-2

    Molecular formula
    C18H36O3

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCCO

    Safety labels

  • Properties

    XLogP3-AA
    6.8

    Molecular weight
    300.5 g/mol

  • Synonyms

    • 2-Hydroxyethyl palmitate
    • Glycol palmitate
    • 4219-49-2
    • 2-Hydroxyethyl hexadecanoate
    • Ethylene glycol monopalmitate
    • Palmitoylglycol
    • Hexadecanoic acid, 2-hydroxyethyl ester
    • Glycol monopalmitate
    • PALMITIC ACID, 2-HYDROXYETHYL ESTER
    • Lanol P
    • NSC 406556
    • EINECS 224-160-8
    • BRN 1789719
    • T80A3T38WE
    • AI3-03503
    • NSC-406556
    • CHEBI:136809
    • DTXSID10863345
    • RefChem:473432
    • Hexadecanoic acid, 2-hydroxyethyl ester (9CI)
    • GLYCOL PALMITATE [INCI]
    • DTXCID60811977
    • 224-160-8
    • 618-403-0
    • 1-monopalmitoylethylene glycol
    • MFCD01709442
    • 9004-94-8
    • UNII-T80A3T38WE
    • mono-C16-EG
    • SCHEMBL406849
    • ethylene glycol monohexadecanoate
    • NSC406556
    • AKOS027321382
    • AS-58105
    • CS-0160236
    • NS00013717
    • D82526
    • Q27289787
    • 9004-94-8

  • Applications

    2-Hydroxyethyl hexadecanoate (CAS 4219-49-2) is commonly used as an emollient and conditioning agent in cosmetics and personal care. In industry, it serves as an intermediate for the synthesis of fatty acid esters and other additives for plastics, and it can act as a plasticizer or lubricating additive in polymer systems. It may function as a nonionic surfactant or co-surfactant in formulations, helping to improve solubility, dispersion, and processability in cleaning, coatings, and inks. In coatings, inks, and plastics applications, it can contribute as a lubricating additive or processing aid to enhance handling and performance of films and materials. Use is formulation-dependent and subject to local regulations.

    gpt-5-nano

1 3

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction