2-Hydroxyethyl 4-[bis[2-(2-hydroxyethoxy)ethyl]amino]benzoate

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  • Identifiers

    CAS number
    116242-27-4

    Molecular formula
    C17H27NO7

    SMILES
    C1=CC(=CC=C1C(=O)OCCO)N(CCOCCO)CCOCCO

    Safety labels

  • Odor profile

    Fragrance
    Odorless 50.01%
    Alcoholic 28.07%
    Sweet 27.61%
    Fishy 20.36%
    Fresh 18.09%
    Savory 17.01%
    Oily 16.9%
    Clean 16.68%
    Milky 16.18%
    Buttery 16.08%

     

    Flavor
    Odorless 47.16%
    Bitter 38.28%
    Sweet 33.68%
    Fruity 33.38%
    Mild 30.95%
    Sweet-like 26.62%
    Fatty 23.32%
    Bland 22.82%
    Very mild 22.42%
    Creamy 22.14%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.5

    pKa est.
    4.7 (weak acid)

    Molecular weight
    357.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1636°C

    Flash point

    • 274.1 ˚C est.

  • Synonyms

    • 116242-27-4
    • 2-hydroxyethyl 4-[bis[2-(2-hydroxyethoxy)ethyl]amino]benzoate
    • SCHEMBL23069367
    • PEG-25PABA Polyethylene Glycol (25) PABA
    • 116242-27-4

  • Applications

    2-Hydroxyethyl 4-[bis[2-(2-hydroxyethoxy)ethyl]amino]benzoate (CAS 116242-27-4) is a multifunctional additive and intermediate used in industrial and consumer formulations. In cosmetics and personal care, it may function as a humectant and emollient and can act as a surfactant or co-solvent in emulsions and cleansing products. In polymers and coatings, it can serve as a processing aid or plasticizer to adjust rheology and flexibility; in coatings/inks, as a compatibility modifier to improve dispersion and film formation. In cleaning and household products, it can contribute as a soluble polyether-containing component to enhance formulation stability. It may also be used as an organic synthesis intermediate in industrial manufacturing. All uses are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.11
    methanol 15.89
    isopropanol 2.05
    water 7.91
    ethyl acetate 3.52
    n-propanol 4.18
    acetone 4.44
    n-butanol 3.2
    acetonitrile 3.21
    DMF 86.22
    toluene 0.88
    isobutanol 2.19
    1,4-dioxane 5.24
    methyl acetate 4.1
    THF 7.45
    2-butanone 3.79
    n-pentanol 2.16
    sec-butanol 2.8
    n-hexane 0.18
    ethylene glycol 12.06
    NMP 107.38
    cyclohexane 0.49
    DMSO 259.41
    n-butyl acetate 1.27
    n-octanol 1.28
    chloroform 6.79
    n-propyl acetate 1.81
    acetic acid 49.49
    dichloromethane 10.55
    cyclohexanone 10.6
    propylene glycol 9.0
    isopropyl acetate 1.96
    DMAc 133.56
    2-ethoxyethanol 17.58
    isopentanol 2.3
    n-heptane 0.26
    ethyl formate 5.14
    1,2-dichloroethane 7.56
    n-hexanol 1.3
    2-methoxyethanol 33.84
    isobutyl acetate 0.79
    tetrachloromethane 1.33
    n-pentyl acetate 1.32
    transcutol 32.41
    n-heptanol 1.35
    ethylbenzene 0.62
    MIBK 1.63
    2-propoxyethanol 8.69
    tert-butanol 2.32
    MTBE 1.23
    2-butoxyethanol 5.96
    propionic acid 13.17
    o-xylene 1.53
    formic acid 87.87
    diethyl ether 1.62
    m-xylene 0.86
    p-xylene 0.72
    chlorobenzene 1.25
    dimethyl carbonate 6.33
    n-octane 0.14
    formamide 110.29
    cyclopentanone 13.37
    2-pentanone 2.84
    anisole 1.81
    cyclopentyl methyl ether 4.08
    gamma-butyrolactone 24.17
    1-methoxy-2-propanol 15.34
    pyridine 6.79
    3-pentanone 3.65
    furfural 26.68
    n-dodecane 0.09
    diethylene glycol 17.46
    diisopropyl ether 0.5
    tert-amyl alcohol 3.35
    acetylacetone 6.64
    n-hexadecane 0.1
    acetophenone 4.29
    methyl propionate 6.45
    isopentyl acetate 1.28
    trichloroethylene 13.63
    n-nonanol 1.34
    cyclohexanol 4.77
    benzyl alcohol 3.96
    2-ethylhexanol 0.99
    isooctanol 1.14
    dipropyl ether 1.45
    1,2-dichlorobenzene 2.0
    ethyl lactate 5.46
    propylene carbonate 9.34
    n-methylformamide 34.11
    2-pentanol 1.72
    n-pentane 0.21
    1-propoxy-2-propanol 5.1
    1-methoxy-2-propyl acetate 4.31
    2-(2-methoxypropoxy) propanol 9.02
    mesitylene 0.67
    ε-caprolactone 11.73
    p-cymene 0.7
    epichlorohydrin 16.12
    1,1,1-trichloroethane 2.54
    2-aminoethanol 15.32
    morpholine-4-carbaldehyde 51.98
    sulfolane 77.8
    2,2,4-trimethylpentane 0.18
    2-methyltetrahydrofuran 4.16
    n-hexyl acetate 1.76
    isooctane 0.06
    2-(2-butoxyethoxy)ethanol 10.16
    sec-butyl acetate 1.11
    tert-butyl acetate 1.97
    decalin 0.23
    glycerin 31.95
    diglyme 23.23
    acrylic acid 21.78
    isopropyl myristate 0.78
    n-butyric acid 10.22
    acetyl acetate 4.44
    di(2-ethylhexyl) phthalate 1.84
    ethyl propionate 2.64
    nitromethane 57.07
    1,2-diethoxyethane 3.29
    benzonitrile 2.56
    trioctyl phosphate 1.28
    1-bromopropane 2.0
    gamma-valerolactone 29.0
    n-decanol 0.96
    triethyl phosphate 3.3
    4-methyl-2-pentanol 0.97
    propionitrile 2.57
    vinylene carbonate 11.03
    1,1,2-trichlorotrifluoroethane 48.74
    DMS 4.08
    cumene 0.53
    2-octanol 0.8
    2-hexanone 1.72
    octyl acetate 1.21
    limonene 1.08
    1,2-dimethoxyethane 15.39
    ethyl orthosilicate 2.81
    tributyl phosphate 1.74
    diacetone alcohol 6.19
    N,N-dimethylaniline 2.65
    acrylonitrile 5.57
    aniline 3.5
    1,3-propanediol 13.08
    bromobenzene 1.04
    dibromomethane 4.82
    1,1,2,2-tetrachloroethane 12.82
    2-methyl-cyclohexyl acetate 2.22
    tetrabutyl urea 3.17
    diisobutyl methanol 0.72
    2-phenylethanol 2.52
    styrene 0.69
    dioctyl adipate 2.36
    dimethyl sulfate 27.06
    ethyl butyrate 2.09
    methyl lactate 13.57
    butyl lactate 3.33
    diethyl carbonate 2.16
    propanediol butyl ether 6.75
    triethyl orthoformate 2.91
    p-tert-butyltoluene 0.65
    methyl 4-tert-butylbenzoate 5.49
    morpholine 10.96
    tert-butylamine 1.12
    n-dodecanol 0.69
    dimethoxymethane 14.59
    ethylene carbonate 7.54
    cyrene 15.7
    2-ethoxyethyl acetate 3.13
    2-ethylhexyl acetate 1.04
    1,2,4-trichlorobenzene 3.42
    4-methylpyridine 4.06
    dibutyl ether 1.07
    2,6-dimethyl-4-heptanol 0.72
    DEF 15.07
    dimethyl isosorbide 13.65
    tetrachloroethylene 9.64
    eugenol 6.18
    triacetin 5.82
    span 80 5.84
    1,4-butanediol 6.67
    1,1-dichloroethane 2.43
    2-methyl-1-pentanol 1.96
    methyl formate 19.61
    2-methyl-1-butanol 2.84
    n-decane 0.18
    butyronitrile 1.91
    3,7-dimethyl-1-octanol 1.08
    1-chlorooctane 0.61
    1-chlorotetradecane 0.24
    n-nonane 0.16
    undecane 0.12
    tert-butylcyclohexane 0.13
    cyclooctane 0.24
    cyclopentanol 5.14
    tetrahydropyran 3.13
    tert-amyl methyl ether 2.08
    2,5,8-trioxanonane 17.67
    1-hexene 0.44
    2-isopropoxyethanol 6.89
    2,2,2-trifluoroethanol 35.09
    methyl butyrate 3.55

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction