2-Hydroxy-4-methylbenzaldehyde

Overview IFRA Request a quote

  • Identifiers

    CAS number
    698-27-1

    Molecular formula
    C8H8O2

    SMILES
    CC1=CC(=C(C=C1)C=O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 78.56%
    Phenolic 70.21%
    Almond 61.73%
    Bitter 56.43%
    Cherry 54.22%
    Fruity 53.26%
    Spicy 50.6%
    Medicinal 48.14%
    Vanilla 45.97%
    Aromatic 36.99%

     

    Flavor
    Bitter 60.01%
    Phenolic 57.97%
    Almond 41.52%
    Medical 34.2%
    Medicinal 30.66%
    Spicy 30.63%
    Woody 30.41%
    Sweet 29.4%
    Nutty 27.96%
    Vanilla 27.32%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.7

    pKa est.
    8.11 (weak base)

    Molecular weight
    136.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Melting point expt.

    • 60 - 61 °C

    Boiling point

    • 760.00 to 223.00 °C. @ 760.00 mm Hg

    Flash point

    • 112.6 ˚C est.

    Solubility expt.

    • very slightly
    • insoluble in water; soluble in organic solvents, oils
    • freely soluble (in ethanol)

  • Synonyms

    • 2-Hydroxy-4-methylbenzaldehyde
    • 698-27-1
    • 4-Methylsalicylaldehyde
    • 2,4-Cresotaldehyde
    • BENZALDEHYDE, 2-HYDROXY-4-METHYL-
    • 2-Formyl-5-methylphenol
    • 4-Methyl-2-hydroxybenzaldehyde
    • m-Homosalicylaldehyde
    • 2-Hydroxy-4-methyl-benzaldehyde
    • 4-Methylsalicyclic aldehyde
    • FEMA No. 3697
    • Homosalicylaldehyde, m-
    • 4-Methyl salicylaldehyde
    • MFCD00799550
    • UNII-9N0S26G61J
    • m-Cresol-6-aldehyde
    • 9N0S26G61J
    • 2-hydroxy-p-tolualdehyde
    • EINECS 211-813-7
    • DTXSID2074407
    • FEMA 3697
    • 2-HYDROXY-4-METHYL BENZALDEHYDE [FHFI]
    • 4-methyl-salicylaldehyde
    • SCHEMBL225766
    • 2-hydroxy 4-methyl benzaldehyde
    • DTXCID5046566
    • 2-Hydroxy-4-methyl benzaldehyde
    • CHEBI:178982
    • CL8286
    • AKOS000112538
    • 2-Hydroxy-4-methylbenzenecarboxaldehyde
    • CS-W007888
    • FH70218
    • HY-W007888
    • 2-Hydroxy-4-methylbenzaldehyde, >=98%
    • BP-12466
    • DS-11894
    • PD158256
    • SY050636
    • M2431
    • NS00022709
    • EN300-83165
    • AE-907/30536011
    • Q15634117
    • Z1203159482

  • Applications

    2-Hydroxy-4-methylbenzaldehyde (CAS 698-27-1) is used as an aroma chemical and fragrance intermediate in perfumery, contributing to floral and woody notes, and is also employed as a scent component in cosmetic formulations. It serves as a chemical intermediate for the synthesis of other substituted salicylaldehyde derivatives and related aromatic compounds in industrial manufacturing. The compound functions as a building block in polymer and resin chemistry, enabling functionalization through its phenolic and aldehyde groups. In coatings and inks, it can act as a precursor to specialty resins and dye/aromatic intermediates. Depending on regulatory constraints, it may be evaluated for use as a flavor/aroma ingredient in formulations, always subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 737.12
    methanol 432.96
    isopropanol 537.31
    water 2.17
    ethyl acetate 780.67
    n-propanol 601.39
    acetone 1208.36
    n-butanol 415.7
    acetonitrile 952.27
    DMF 890.93
    toluene 40.81
    isobutanol 345.38
    1,4-dioxane 850.34
    methyl acetate 821.76
    THF 2079.22
    2-butanone 830.36
    n-pentanol 261.27
    sec-butanol 429.27
    n-hexane 9.98
    ethylene glycol 119.67
    NMP 664.06
    cyclohexane 6.54
    DMSO 1484.66
    n-butyl acetate 248.26
    n-octanol 97.59
    chloroform 293.02
    n-propyl acetate 320.05
    acetic acid 535.36
    dichloromethane 367.92
    cyclohexanone 597.79
    propylene glycol 185.31
    isopropyl acetate 308.54
    DMAc 392.57
    2-ethoxyethanol 372.95
    isopentanol 280.45
    n-heptane 12.3
    ethyl formate 349.55
    1,2-dichloroethane 370.16
    n-hexanol 261.66
    2-methoxyethanol 710.14
    isobutyl acetate 163.65
    tetrachloromethane 37.4
    n-pentyl acetate 112.56
    transcutol 902.12
    n-heptanol 102.25
    ethylbenzene 34.52
    MIBK 285.5
    2-propoxyethanol 430.21
    tert-butanol 550.17
    MTBE 346.88
    2-butoxyethanol 198.36
    propionic acid 551.98
    o-xylene 36.96
    formic acid 203.04
    diethyl ether 478.94
    m-xylene 52.18
    p-xylene 47.84
    chlorobenzene 92.7
    dimethyl carbonate 247.25
    n-octane 5.68
    formamide 500.61
    cyclopentanone 1265.77
    2-pentanone 625.8
    anisole 170.64
    cyclopentyl methyl ether 480.39
    gamma-butyrolactone 1537.02
    1-methoxy-2-propanol 556.2
    pyridine 284.38
    3-pentanone 371.62
    furfural 526.76
    n-dodecane 6.78
    diethylene glycol 336.43
    diisopropyl ether 101.43
    tert-amyl alcohol 351.53
    acetylacetone 556.82
    n-hexadecane 7.5
    acetophenone 148.49
    methyl propionate 589.76
    isopentyl acetate 200.43
    trichloroethylene 591.3
    n-nonanol 85.36
    cyclohexanol 212.04
    benzyl alcohol 112.47
    2-ethylhexanol 113.7
    isooctanol 84.2
    dipropyl ether 152.19
    1,2-dichlorobenzene 91.22
    ethyl lactate 133.51
    propylene carbonate 490.03
    n-methylformamide 695.02
    2-pentanol 286.16
    n-pentane 9.2
    1-propoxy-2-propanol 267.17
    1-methoxy-2-propyl acetate 275.73
    2-(2-methoxypropoxy) propanol 179.67
    mesitylene 38.82
    ε-caprolactone 484.9
    p-cymene 37.11
    epichlorohydrin 1339.04
    1,1,1-trichloroethane 290.77
    2-aminoethanol 271.68
    morpholine-4-carbaldehyde 530.7
    sulfolane 1094.46
    2,2,4-trimethylpentane 10.01
    2-methyltetrahydrofuran 1100.43
    n-hexyl acetate 178.38
    isooctane 11.58
    2-(2-butoxyethoxy)ethanol 269.6
    sec-butyl acetate 194.65
    tert-butyl acetate 324.37
    decalin 9.69
    glycerin 218.29
    diglyme 469.61
    acrylic acid 382.55
    isopropyl myristate 76.68
    n-butyric acid 507.68
    acetyl acetate 307.15
    di(2-ethylhexyl) phthalate 62.86
    ethyl propionate 274.72
    nitromethane 1246.63
    1,2-diethoxyethane 232.6
    benzonitrile 138.67
    trioctyl phosphate 57.68
    1-bromopropane 163.66
    gamma-valerolactone 947.38
    n-decanol 66.7
    triethyl phosphate 81.64
    4-methyl-2-pentanol 140.84
    propionitrile 474.52
    vinylene carbonate 340.09
    1,1,2-trichlorotrifluoroethane 371.85
    DMS 184.73
    cumene 35.01
    2-octanol 69.75
    2-hexanone 326.21
    octyl acetate 100.58
    limonene 55.02
    1,2-dimethoxyethane 513.71
    ethyl orthosilicate 72.2
    tributyl phosphate 66.41
    diacetone alcohol 402.86
    N,N-dimethylaniline 95.26
    acrylonitrile 502.0
    aniline 117.67
    1,3-propanediol 424.43
    bromobenzene 70.2
    dibromomethane 179.44
    1,1,2,2-tetrachloroethane 378.99
    2-methyl-cyclohexyl acetate 127.9
    tetrabutyl urea 80.42
    diisobutyl methanol 72.64
    2-phenylethanol 139.53
    styrene 37.26
    dioctyl adipate 107.86
    dimethyl sulfate 335.45
    ethyl butyrate 176.24
    methyl lactate 220.63
    butyl lactate 98.7
    diethyl carbonate 123.05
    propanediol butyl ether 178.0
    triethyl orthoformate 105.8
    p-tert-butyltoluene 38.79
    methyl 4-tert-butylbenzoate 145.94
    morpholine 1008.89
    tert-butylamine 227.45
    n-dodecanol 51.92
    dimethoxymethane 613.3
    ethylene carbonate 299.69
    cyrene 194.61
    2-ethoxyethyl acetate 187.69
    2-ethylhexyl acetate 136.18
    1,2,4-trichlorobenzene 121.62
    4-methylpyridine 235.21
    dibutyl ether 100.05
    2,6-dimethyl-4-heptanol 72.64
    DEF 408.33
    dimethyl isosorbide 327.76
    tetrachloroethylene 185.71
    eugenol 139.0
    triacetin 175.92
    span 80 141.69
    1,4-butanediol 133.31
    1,1-dichloroethane 364.54
    2-methyl-1-pentanol 180.34
    methyl formate 551.14
    2-methyl-1-butanol 263.4
    n-decane 10.04
    butyronitrile 385.04
    3,7-dimethyl-1-octanol 96.6
    1-chlorooctane 52.55
    1-chlorotetradecane 22.09
    n-nonane 9.35
    undecane 8.19
    tert-butylcyclohexane 13.2
    cyclooctane 3.53
    cyclopentanol 442.42
    tetrahydropyran 734.32
    tert-amyl methyl ether 213.07
    2,5,8-trioxanonane 312.02
    1-hexene 62.06
    2-isopropoxyethanol 259.98
    2,2,2-trifluoroethanol 208.68
    methyl butyrate 345.18

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction