2-Hydroxy-4-methoxy-4'-methylbenzophenone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    1641-17-4

    Molecular formula
    C15H14O3

    SMILES
    CC1=CC=C(C=C1)C(=O)C2=C(C=C(C=C2)OC)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 81.23%
    Floral 60.16%
    Phenolic 50.05%
    Balsamic 45.94%
    Powdery 42.54%
    Vanilla 41.94%
    Aromatic 38.02%
    Cherry 37.4%
    Hawthorn 37.37%
    Herbal 36.77%

     

    Flavor
    Bitter 80.4%
    Odorless 22.86%
    Wintergreen 22.46%
    Lovage 21.85%
    Balsam 21.69%
    Ethyl benzoate 20.56%
    Parsley 20.5%
    Very strong 20.25%
    Phenolic 20.23%
    Indole 20.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.0

    pKa est.
    9.39 (weak base)

    Molecular weight
    242.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    379°C

    Melting point expt.

    • 98 °C (208 °F)

    Flash point

    • 165.23 ˚C est.

  • Synonyms

    • Mexenone
    • 1641-17-4
    • 2-Hydroxy-4-methoxy-4'-methylbenzophenone
    • Uvistat
    • Mesenone
    • Mexenona
    • MEXENEONE
    • Mexenonum
    • Uvistat L
    • ET1UGF4A0B
    • NSC-760432
    • DTXSID8046242
    • DTXCID6026242
    • RefChem:158432
    • 216-688-2
    • Benzophenone-10
    • (2-Hydroxy-4-methoxyphenyl)(4-methylphenyl)methanone
    • (2-hydroxy-4-methoxyphenyl)(p-tolyl)methanone
    • Methanone, (2-hydroxy-4-methoxyphenyl)(4-methylphenyl)-
    • (2-hydroxy-4-methoxyphenyl)-(4-methylphenyl)methanone
    • Benzophenone 10
    • 5-methoxy-2-(4-methylbenzoyl)phenol
    • MFCD00017172
    • NCGC00160579-01
    • Mesenone [DCIT]
    • SMR001826585
    • CAS-1641-17-4
    • 2-hydroxy-4-methoxyphenyl 4-methylphenyl ketone
    • Mexenone [INN:BAN]
    • Mexenonum [INN-Latin]
    • Mexenona [INN-Spanish]
    • UNII-ET1UGF4A0B
    • EINECS 216-688-2
    • Mexenone (Standard)
    • MEXENONE [INN]
    • MEXENONE [MI]
    • MEXENONE [MART.]
    • MEXENONE [WHO-DD]
    • SCHEMBL39448
    • MLS004774060
    • MLS006011615
    • orb1311018
    • orb3025316
    • CHEMBL1898387
    • SCHEMBL29365598
    • HSDB 8475
    • HY-B1023R
    • MSK3450
    • CHEBI:134985
    • HMS3264C15
    • HMS5085G13
    • Pharmakon1600-01506199
    • ALBB-025889
    • BB_SC-06818
    • HY-B1023
    • Tox21_111913
    • Tox21_200930
    • BBL027831
    • MSK3450-100A
    • NSC760432
    • s5692
    • SBB057984
    • STL236751
    • AKOS015955442
    • MSK3450-1000A
    • CCG-214045
    • CS-4539
    • FH71545
    • NSC 760432
    • NCGC00160579-02
    • NCGC00258484-01
    • VS-08598
    • 2-hydroxy-4-methoxy 4'-methylbenzophenone
    • NS00013402
    • ST45029059
    • F72576
    • (2-hydroxy-4-methoxy-phenyl)-(p-tolyl)methanone
    • AB01563254_01
    • SR-01000940330
    • SR-01000940330-2
    • BRD-K18613660-001-01-4
    • BRD-K18613660-001-05-5
    • Q18344257
    • 2-Hydroxy-4-methoxy-4'-methylbenzophenone Solution in Acetonitrile, 1000ug/mL
    • 2-Hydroxy-4-methoxy-4'-methylbenzophenone Solution in Acetonitrile, 100ug/mL
    • 1641-17-4

  • Applications

    2-Hydroxy-4-methoxy-4'-methylbenzophenone (CAS 1641-17-4) is commonly evaluated as a UV-absorber and light stabilizer in cosmetic and personal care formulations, and as a light stabilizer for plastics, polymers, coatings, and inks to improve lightfastness; it may function as a photoinitiator or photosensitizer in UV-curing systems used in coatings and adhesives; it also serves as an intermediate in the synthesis of other benzophenone derivatives; and it may be used to enhance photostability of polymers used in electronics and packaging.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 116.3
    methanol 130.56
    isopropanol 78.16
    water 0.02
    ethyl acetate 291.41
    n-propanol 117.42
    acetone 289.21
    n-butanol 70.79
    acetonitrile 241.68
    DMF 436.33
    toluene 50.91
    isobutanol 56.11
    1,4-dioxane 367.16
    methyl acetate 343.13
    THF 716.23
    2-butanone 328.17
    n-pentanol 50.0
    sec-butanol 74.93
    n-hexane 0.49
    ethylene glycol 49.28
    NMP 216.34
    cyclohexane 1.25
    DMSO 810.68
    n-butyl acetate 88.71
    n-octanol 12.64
    chloroform 382.59
    n-propyl acetate 104.79
    acetic acid 131.59
    dichloromethane 360.52
    cyclohexanone 237.11
    propylene glycol 142.67
    isopropyl acetate 122.88
    DMAc 503.06
    2-ethoxyethanol 187.98
    isopentanol 58.2
    n-heptane 0.66
    ethyl formate 80.13
    1,2-dichloroethane 335.38
    n-hexanol 40.47
    2-methoxyethanol 455.49
    isobutyl acetate 58.51
    tetrachloromethane 11.76
    n-pentyl acetate 33.08
    transcutol 690.82
    n-heptanol 17.38
    ethylbenzene 22.63
    MIBK 100.68
    2-propoxyethanol 169.12
    tert-butanol 145.29
    MTBE 108.74
    2-butoxyethanol 66.31
    propionic acid 123.4
    o-xylene 23.91
    formic acid 51.93
    diethyl ether 109.5
    m-xylene 27.29
    p-xylene 26.05
    chlorobenzene 76.66
    dimethyl carbonate 158.15
    n-octane 0.38
    formamide 212.3
    cyclopentanone 436.92
    2-pentanone 179.45
    anisole 120.62
    cyclopentyl methyl ether 155.1
    gamma-butyrolactone 423.72
    1-methoxy-2-propanol 302.5
    pyridine 241.12
    3-pentanone 146.28
    furfural 253.6
    n-dodecane 0.69
    diethylene glycol 171.52
    diisopropyl ether 22.69
    tert-amyl alcohol 100.26
    acetylacetone 278.74
    n-hexadecane 0.84
    acetophenone 99.89
    methyl propionate 272.93
    isopentyl acetate 80.81
    trichloroethylene 604.9
    n-nonanol 13.69
    cyclohexanol 62.47
    benzyl alcohol 90.63
    2-ethylhexanol 25.06
    isooctanol 16.8
    dipropyl ether 35.92
    1,2-dichlorobenzene 67.06
    ethyl lactate 65.92
    propylene carbonate 149.14
    n-methylformamide 234.36
    2-pentanol 43.79
    n-pentane 0.32
    1-propoxy-2-propanol 109.03
    1-methoxy-2-propyl acetate 156.43
    2-(2-methoxypropoxy) propanol 105.84
    mesitylene 15.18
    ε-caprolactone 175.94
    p-cymene 14.05
    epichlorohydrin 665.95
    1,1,1-trichloroethane 164.56
    2-aminoethanol 122.96
    morpholine-4-carbaldehyde 312.27
    sulfolane 463.23
    2,2,4-trimethylpentane 1.44
    2-methyltetrahydrofuran 260.98
    n-hexyl acetate 48.53
    isooctane 1.34
    2-(2-butoxyethoxy)ethanol 146.71
    sec-butyl acetate 73.68
    tert-butyl acetate 146.03
    decalin 2.19
    glycerin 187.05
    diglyme 313.67
    acrylic acid 118.13
    isopropyl myristate 23.56
    n-butyric acid 122.65
    acetyl acetate 125.81
    di(2-ethylhexyl) phthalate 27.04
    ethyl propionate 105.13
    nitromethane 549.59
    1,2-diethoxyethane 140.05
    benzonitrile 83.33
    trioctyl phosphate 17.03
    1-bromopropane 77.32
    gamma-valerolactone 419.47
    n-decanol 11.18
    triethyl phosphate 42.82
    4-methyl-2-pentanol 29.61
    propionitrile 143.05
    vinylene carbonate 124.82
    1,1,2-trichlorotrifluoroethane 318.62
    DMS 107.72
    cumene 15.36
    2-octanol 10.45
    2-hexanone 99.85
    octyl acetate 27.99
    limonene 18.91
    1,2-dimethoxyethane 283.78
    ethyl orthosilicate 37.22
    tributyl phosphate 25.66
    diacetone alcohol 196.63
    N,N-dimethylaniline 55.68
    acrylonitrile 217.04
    aniline 112.76
    1,3-propanediol 168.72
    bromobenzene 70.07
    dibromomethane 163.08
    1,1,2,2-tetrachloroethane 428.69
    2-methyl-cyclohexyl acetate 54.75
    tetrabutyl urea 33.4
    diisobutyl methanol 19.44
    2-phenylethanol 71.79
    styrene 33.06
    dioctyl adipate 46.26
    dimethyl sulfate 239.43
    ethyl butyrate 68.75
    methyl lactate 135.1
    butyl lactate 41.08
    diethyl carbonate 59.36
    propanediol butyl ether 67.65
    triethyl orthoformate 54.13
    p-tert-butyltoluene 14.59
    methyl 4-tert-butylbenzoate 70.98
    morpholine 503.02
    tert-butylamine 45.42
    n-dodecanol 9.18
    dimethoxymethane 384.29
    ethylene carbonate 103.72
    cyrene 102.05
    2-ethoxyethyl acetate 90.88
    2-ethylhexyl acetate 57.28
    1,2,4-trichlorobenzene 94.65
    4-methylpyridine 180.36
    dibutyl ether 26.3
    2,6-dimethyl-4-heptanol 19.44
    DEF 165.43
    dimethyl isosorbide 187.06
    tetrachloroethylene 158.41
    eugenol 72.43
    triacetin 84.1
    span 80 60.29
    1,4-butanediol 42.62
    1,1-dichloroethane 211.63
    2-methyl-1-pentanol 47.64
    methyl formate 154.45
    2-methyl-1-butanol 51.85
    n-decane 0.98
    butyronitrile 83.17
    3,7-dimethyl-1-octanol 22.37
    1-chlorooctane 8.44
    1-chlorotetradecane 4.07
    n-nonane 0.75
    undecane 0.8
    tert-butylcyclohexane 2.31
    cyclooctane 0.46
    cyclopentanol 85.68
    tetrahydropyran 236.46
    tert-amyl methyl ether 75.81
    2,5,8-trioxanonane 214.96
    1-hexene 6.79
    2-isopropoxyethanol 116.62
    2,2,2-trifluoroethanol 54.01
    methyl butyrate 116.07

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction