2-Hydroxy-22-methyltetracosanoic acid

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  • Identifiers

    CAS number
    52900-16-0

    Molecular formula
    C25H50O3

    SMILES
    CCC(C)CCCCCCCCCCCCCCCCCCCC(C(=O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 74.88%
    Fatty 58.69%
    Oily 36.0%
    Odorless 35.7%
    Creamy 20.35%
    Savory 20.24%
    Milky 18.61%
    Meaty 18.21%
    Fishy 17.31%
    Dairy 16.88%

     

    Flavor
    Waxy 41.3%
    Mild 37.82%
    Bland 37.6%
    Fatty 36.21%
    Odorless 31.29%
    Faint 31.22%
    Fat 24.8%
    Slightly waxy 24.02%
    Oily 23.45%
    Delicate 22.19%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    11.0

    pKa est.
    7.45 (neutral)

    Molecular weight
    398.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    498°C

    Flash point

    • 227.92 ˚C est.

  • Synonyms

    • 2-Hydroxy-22-methyltetracosanoic acid
    • 52900-16-0
    • RefChem:87363
    • 2-Hydroxy-22-methyltetracosanoate
    • CHEBI:172636
    • DTXSID001285510
    • LMFA01030969
    • 52900-16-0

  • Applications

    2-Hydroxy-22-methyltetracosanoic acid (CAS 52900-16-0) is a long-chain hydroxy fatty acid that serves as a building block for specialty esters and polymeric materials; in industry it is used as a raw material for the synthesis of wax esters and bio-based lubricants and as an intermediate for polyester-like polymers and coatings; in cosmetics and personal care it may be used, after derivatization, as an emollient and as a basis for ester-based surfactants and thickening agents; in coatings and inks it can function as a bio-based additive influencing film formation and rheology; and it can be explored as a plasticizer or additive in adhesives and polymer formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.88
    methanol 3.75
    isopropanol 2.76
    water 0.03
    ethyl acetate 12.75
    n-propanol 3.64
    acetone 8.72
    n-butanol 4.21
    acetonitrile 1.92
    DMF 19.38
    toluene 5.48
    isobutanol 3.55
    1,4-dioxane 19.79
    methyl acetate 8.83
    THF 81.59
    2-butanone 14.13
    n-pentanol 5.42
    sec-butanol 4.98
    n-hexane 2.63
    ethylene glycol 0.38
    NMP 85.46
    cyclohexane 8.98
    DMSO 38.41
    n-butyl acetate 26.35
    n-octanol 13.77
    chloroform 39.4
    n-propyl acetate 24.95
    acetic acid 6.57
    dichloromethane 37.03
    cyclohexanone 56.8
    propylene glycol 1.31
    isopropyl acetate 19.04
    DMAc 63.65
    2-ethoxyethanol 15.94
    isopentanol 6.76
    n-heptane 3.61
    ethyl formate 6.43
    1,2-dichloroethane 26.3
    n-hexanol 5.85
    2-methoxyethanol 11.95
    isobutyl acetate 19.71
    tetrachloromethane 14.7
    n-pentyl acetate 58.02
    transcutol 136.99
    n-heptanol 12.35
    ethylbenzene 7.8
    MIBK 20.32
    2-propoxyethanol 17.75
    tert-butanol 8.51
    MTBE 17.24
    2-butoxyethanol 34.51
    propionic acid 6.28
    o-xylene 8.67
    formic acid 2.08
    diethyl ether 8.23
    m-xylene 6.71
    p-xylene 10.53
    chlorobenzene 10.47
    dimethyl carbonate 5.88
    n-octane 2.75
    formamide 4.38
    cyclopentanone 62.62
    2-pentanone 15.19
    anisole 14.64
    cyclopentyl methyl ether 37.48
    gamma-butyrolactone 56.5
    1-methoxy-2-propanol 16.08
    pyridine 16.93
    3-pentanone 15.35
    furfural 35.22
    n-dodecane 1.35
    diethylene glycol 6.45
    diisopropyl ether 8.16
    tert-amyl alcohol 12.85
    acetylacetone 26.57
    n-hexadecane 1.62
    acetophenone 24.33
    methyl propionate 12.29
    isopentyl acetate 35.19
    trichloroethylene 49.3
    n-nonanol 15.38
    cyclohexanol 12.51
    benzyl alcohol 8.41
    2-ethylhexanol 9.85
    isooctanol 15.81
    dipropyl ether 19.0
    1,2-dichlorobenzene 18.21
    ethyl lactate 13.46
    propylene carbonate 33.86
    n-methylformamide 6.18
    2-pentanol 4.94
    n-pentane 1.42
    1-propoxy-2-propanol 25.49
    1-methoxy-2-propyl acetate 37.03
    2-(2-methoxypropoxy) propanol 39.75
    mesitylene 7.2
    ε-caprolactone 59.94
    p-cymene 9.98
    epichlorohydrin 50.41
    1,1,1-trichloroethane 34.66
    2-aminoethanol 1.59
    morpholine-4-carbaldehyde 47.05
    sulfolane 141.78
    2,2,4-trimethylpentane 3.56
    2-methyltetrahydrofuran 47.75
    n-hexyl acetate 51.72
    isooctane 1.93
    2-(2-butoxyethoxy)ethanol 51.75
    sec-butyl acetate 26.02
    tert-butyl acetate 42.27
    decalin 6.21
    glycerin 3.17
    diglyme 105.14
    acrylic acid 4.38
    isopropyl myristate 18.44
    n-butyric acid 15.19
    acetyl acetate 11.56
    di(2-ethylhexyl) phthalate 14.91
    ethyl propionate 22.42
    nitromethane 13.91
    1,2-diethoxyethane 45.71
    benzonitrile 8.72
    trioctyl phosphate 12.39
    1-bromopropane 14.58
    gamma-valerolactone 85.57
    n-decanol 9.32
    triethyl phosphate 24.43
    4-methyl-2-pentanol 6.3
    propionitrile 3.15
    vinylene carbonate 19.7
    1,1,2-trichlorotrifluoroethane 44.52
    DMS 21.41
    cumene 8.05
    2-octanol 13.42
    2-hexanone 21.91
    octyl acetate 21.1
    limonene 16.36
    1,2-dimethoxyethane 40.67
    ethyl orthosilicate 26.59
    tributyl phosphate 16.12
    diacetone alcohol 41.75
    N,N-dimethylaniline 16.35
    acrylonitrile 3.09
    aniline 5.96
    1,3-propanediol 3.78
    bromobenzene 12.68
    dibromomethane 24.27
    1,1,2,2-tetrachloroethane 60.05
    2-methyl-cyclohexyl acetate 37.63
    tetrabutyl urea 26.56
    diisobutyl methanol 11.36
    2-phenylethanol 10.39
    styrene 6.88
    dioctyl adipate 33.32
    dimethyl sulfate 20.13
    ethyl butyrate 31.91
    methyl lactate 8.9
    butyl lactate 40.2
    diethyl carbonate 16.63
    propanediol butyl ether 27.96
    triethyl orthoformate 35.19
    p-tert-butyltoluene 10.54
    methyl 4-tert-butylbenzoate 52.63
    morpholine 27.85
    tert-butylamine 6.49
    n-dodecanol 6.16
    dimethoxymethane 14.61
    ethylene carbonate 18.56
    cyrene 38.51
    2-ethoxyethyl acetate 56.46
    2-ethylhexyl acetate 30.55
    1,2,4-trichlorobenzene 23.9
    4-methylpyridine 15.13
    dibutyl ether 28.39
    2,6-dimethyl-4-heptanol 11.36
    DEF 25.98
    dimethyl isosorbide 93.87
    tetrachloroethylene 37.04
    eugenol 38.31
    triacetin 57.41
    span 80 36.55
    1,4-butanediol 2.13
    1,1-dichloroethane 18.56
    2-methyl-1-pentanol 9.0
    methyl formate 4.54
    2-methyl-1-butanol 6.4
    n-decane 3.55
    butyronitrile 4.45
    3,7-dimethyl-1-octanol 15.92
    1-chlorooctane 14.88
    1-chlorotetradecane 4.17
    n-nonane 3.33
    undecane 2.01
    tert-butylcyclohexane 5.15
    cyclooctane 3.58
    cyclopentanol 12.79
    tetrahydropyran 28.93
    tert-amyl methyl ether 21.64
    2,5,8-trioxanonane 62.58
    1-hexene 5.42
    2-isopropoxyethanol 15.9
    2,2,2-trifluoroethanol 5.37
    methyl butyrate 31.52

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction