2-Hydroxy-1,8-cineole

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    60761-00-4

    Molecular formula
    C10H18O2

    SMILES
    CC1([C@@H]2CCC(O1)([C@H](C2)O)C)C

    Retention indicies (RI)

    • Carbowax: 1824.0

  • Odor profile

    Mint 57.6%
    Camphoreous 56.77%
    Herbal 54.83%
    Woody 54.05%
    Cooling 46.42%
    Earthy 45.57%
    Fresh 43.68%
    Sweet 41.55%
    Pine 41.27%
    Musty 35.46%

    Scent© AI

  • Properties

    XLogP3-AA
    1.2

    Molecular weight
    170.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    241°C

    Flash point est.
    91.78 ˚C

  • Synonyms

    • 2-Hydroxy-1,8-cineole
    • 60761-00-4
    • SCHEMBL25873961
    • FS-8865

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 209.97
    methanol 395.42
    isopropanol 147.66
    water 24.83
    ethyl acetate 150.97
    n-propanol 179.73
    acetone 142.75
    n-butanol 136.56
    acetonitrile 172.01
    DMF 218.79
    toluene 89.31
    isobutanol 117.54
    1,4-dioxane 314.03
    methyl acetate 156.48
    THF 410.07
    2-butanone 140.97
    n-pentanol 81.79
    sec-butanol 106.1
    n-hexane 10.68
    ethylene glycol 116.26
    NMP 176.86
    cyclohexane 17.69
    DMSO 203.64
    n-butyl acetate 118.24
    n-octanol 90.1
    chloroform 452.01
    n-propyl acetate 73.3
    acetic acid 159.6
    dichloromethane 358.34
    cyclohexanone 180.75
    propylene glycol 102.13
    isopropyl acetate 103.41
    DMAc 168.9
    2-ethoxyethanol 154.51
    isopentanol 99.67
    n-heptane 15.32
    ethyl formate 126.35
    1,2-dichloroethane 171.82
    n-hexanol 151.71
    2-methoxyethanol 286.16
    isobutyl acetate 61.53
    tetrachloromethane 103.61
    n-pentyl acetate 89.57
    transcutol 393.55
    n-heptanol 91.84
    ethylbenzene 46.62
    MIBK 86.99
    2-propoxyethanol 283.12
    tert-butanol 146.36
    MTBE 95.25
    2-butoxyethanol 162.42
    propionic acid 143.36
    o-xylene 69.57
    formic acid 160.38
    diethyl ether 120.44
    m-xylene 83.69
    p-xylene 64.91
    chlorobenzene 124.71
    dimethyl carbonate 75.06
    n-octane 8.99
    formamide 156.47
    cyclopentanone 237.06
    2-pentanone 112.21
    anisole 101.11
    cyclopentyl methyl ether 144.94
    gamma-butyrolactone 288.14
    1-methoxy-2-propanol 205.23
    pyridine 174.01
    3-pentanone 93.05
    furfural 271.29
    n-dodecane 8.68
    diethylene glycol 248.61
    diisopropyl ether 47.55
    tert-amyl alcohol 98.27
    acetylacetone 151.87
    n-hexadecane 9.77
    acetophenone 89.83
    methyl propionate 125.04
    isopentyl acetate 110.14
    trichloroethylene 310.76
    n-nonanol 76.7
    cyclohexanol 101.55
    benzyl alcohol 88.73
    2-ethylhexanol 79.13
    isooctanol 68.86
    dipropyl ether 75.93
    1,2-dichlorobenzene 119.6
    ethyl lactate 65.18
    propylene carbonate 159.34
    n-methylformamide 188.14
    2-pentanol 82.88
    n-pentane 15.21
    1-propoxy-2-propanol 170.09
    1-methoxy-2-propyl acetate 151.7
    2-(2-methoxypropoxy) propanol 124.6
    mesitylene 59.28
    ε-caprolactone 181.3
    p-cymene 50.22
    epichlorohydrin 297.38
    1,1,1-trichloroethane 181.34
    2-aminoethanol 164.71
    morpholine-4-carbaldehyde 256.17
    sulfolane 258.89
    2,2,4-trimethylpentane 11.0
    2-methyltetrahydrofuran 194.0
    n-hexyl acetate 125.69
    isooctane 11.09
    2-(2-butoxyethoxy)ethanol 167.74
    sec-butyl acetate 59.27
    tert-butyl acetate 108.17
    decalin 13.89
    glycerin 156.32
    diglyme 293.55
    acrylic acid 128.58
    isopropyl myristate 57.08
    n-butyric acid 157.2
    acetyl acetate 118.2
    di(2-ethylhexyl) phthalate 54.89
    ethyl propionate 74.95
    nitromethane 249.62
    1,2-diethoxyethane 134.93
    benzonitrile 122.85
    trioctyl phosphate 48.21
    1-bromopropane 105.85
    gamma-valerolactone 333.62
    n-decanol 56.33
    triethyl phosphate 54.27
    4-methyl-2-pentanol 63.8
    propionitrile 142.08
    vinylene carbonate 163.62
    1,1,2-trichlorotrifluoroethane 197.33
    DMS 101.96
    cumene 43.84
    2-octanol 60.39
    2-hexanone 76.72
    octyl acetate 69.13
    limonene 57.22
    1,2-dimethoxyethane 203.22
    ethyl orthosilicate 54.14
    tributyl phosphate 55.86
    diacetone alcohol 121.98
    N,N-dimethylaniline 70.76
    acrylonitrile 168.07
    aniline 114.12
    1,3-propanediol 176.55
    bromobenzene 125.99
    dibromomethane 218.93
    1,1,2,2-tetrachloroethane 244.45
    2-methyl-cyclohexyl acetate 75.38
    tetrabutyl urea 63.09
    diisobutyl methanol 55.9
    2-phenylethanol 119.54
    styrene 50.02
    dioctyl adipate 67.23
    dimethyl sulfate 110.34
    ethyl butyrate 82.8
    methyl lactate 90.02
    butyl lactate 81.21
    diethyl carbonate 63.11
    propanediol butyl ether 128.87
    triethyl orthoformate 69.92
    p-tert-butyltoluene 53.36
    methyl 4-tert-butylbenzoate 107.83
    morpholine 267.46
    tert-butylamine 100.18
    n-dodecanol 43.55
    dimethoxymethane 195.57
    ethylene carbonate 148.57
    cyrene 98.67
    2-ethoxyethyl acetate 127.77
    2-ethylhexyl acetate 88.86
    1,2,4-trichlorobenzene 132.36
    4-methylpyridine 161.53
    dibutyl ether 70.02
    2,6-dimethyl-4-heptanol 55.9
    DEF 106.95
    dimethyl isosorbide 184.73
    tetrachloroethylene 188.38
    eugenol 107.86
    triacetin 113.85
    span 80 99.24
    1,4-butanediol 73.78
    1,1-dichloroethane 182.22
    2-methyl-1-pentanol 66.46
    methyl formate 172.18
    2-methyl-1-butanol 92.69
    n-decane 14.51
    butyronitrile 128.96
    3,7-dimethyl-1-octanol 79.47
    1-chlorooctane 53.67
    1-chlorotetradecane 23.45
    n-nonane 13.4
    undecane 10.89
    tert-butylcyclohexane 15.81
    cyclooctane 10.49
    cyclopentanol 127.65
    tetrahydropyran 196.45
    tert-amyl methyl ether 75.77
    2,5,8-trioxanonane 201.44
    1-hexene 33.94
    2-isopropoxyethanol 106.46
    2,2,2-trifluoroethanol 111.74
    methyl butyrate 84.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Nepeta crassifolia Nepeta crassifolia Boiss. & Buhse, fam. Lamiaceae (Labiatae) 0.2%
Turmeric 3 8024-37-1 Curcuma longa L. (C. domestica Val.), fam. Zingiberaceae 0.05%
Laurel leaf (Turkey) 2a hydrodistilled 8006-78-8 Laurus nobilis L., fam. Lauraceae 0.4%