2-(Hexyloxy)ethanol

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  • Identifiers

    CAS number
    112-25-4

    Molecular formula
    C8H18O2

    SMILES
    CCCCCCOCCO

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Green 80.65%
    Sweet 63.44%
    Oily 61.95%
    Fruity 60.71%
    Herbal 51.0%
    Fresh 50.37%
    Floral 48.09%
    Alcoholic 44.94%
    Fermented 39.35%
    Musty 38.4%

     

    Flavor
    Sweet 60.1%
    Green 48.78%
    Herbal 42.93%
    Fruity 40.41%
    Oil 37.64%
    Earthy 37.05%
    Mushroom 37.01%
    Musty 33.59%
    Alcoholic 31.81%
    Oily 31.24%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    7.61 (neutral)

    Molecular weight
    146.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    209°C

    Flash point

    • 89.22 ˚C est.

  • Synonyms

    • 2-(Hexyloxy)ethanol
    • 112-25-4
    • Ethylene glycol monohexyl ether
    • 2-Hexyloxyethanol
    • Ethanol, 2-(hexyloxy)-
    • 2-HEXOXYETHANOL
    • Hexyl cellosolve
    • n-Hexyl cellosolve
    • 2-Hexyloxy-1-ethanol
    • Glycol monohexyl ether
    • Cellosolve, N-hexyl-
    • Ethylene glycol n-hexyl ether
    • MFCD00045997
    • DTXSID1026908
    • 7P0O8282NR
    • Ethylene glycol mono-n-hexyl ether
    • 31726-34-8
    • DTXCID606908
    • Ethanol, 2-hexyloxy-
    • 2-(hexyloxy)ethan-1-ol
    • CAS-112-25-4
    • Ethylene glycol-n-monohexyl ether
    • HSDB 5569
    • EINECS 203-951-1
    • BRN 1734691
    • hexyloxyethanol
    • Hexylglycol
    • UNII-7P0O8282NR
    • 2-hexyloxy-ethanol
    • 2-(n-Hexyloxy)ethanol
    • Ethylenglykolmonohexylether
    • 2-(1-Hexyloxy) ethanol
    • EC 203-951-1
    • SCHEMBL24741
    • 4-01-00-02383 (Beilstein Handbook Reference)
    • C6E1
    • CHEMBL3188016
    • HY-W130500A
    • Tox21_202105
    • Tox21_300545
    • AKOS009156771
    • Ethylene glycol monohexyl ether, 99%
    • NCGC00248089-01
    • NCGC00248089-02
    • NCGC00254448-01
    • NCGC00259654-01
    • LS-13544
    • DB-041064
    • H0343
    • NS00007590
    • EN300-114321
    • F71224
    • Q27268660
    • Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)

  • Applications

    2-(Hexyloxy)ethanol (CAS 112-25-4) is used mainly as a solvent and processing aid across multiple industries. In cosmetics and personal care, it serves as a humectant and solvent; in household products and cleaners, it functions as a solvent for detergents and surfactants; in industrial manufacturing, it acts as a co-solvent and processing aid in coatings, inks, and adhesives; it also serves as an intermediate for the synthesis of other chemicals and polymer additives, and may be used as a carrier or co-solvent in electronics-related coatings and cleaning formulations, with use subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10338.23
    methanol 12110.12
    isopropanol 7466.14
    water 2.27
    ethyl acetate 2982.19
    n-propanol 7647.28
    acetone 4987.87
    n-butanol 6776.7
    acetonitrile 2733.53
    DMF 2680.1
    toluene 461.03
    isobutanol 4513.87
    1,4-dioxane 4416.8
    methyl acetate 2105.92
    THF 5755.92
    2-butanone 2557.41
    n-pentanol 3087.56
    sec-butanol 4604.06
    n-hexane 653.29
    ethylene glycol 1489.8
    NMP 1329.33
    cyclohexane 1174.01
    DMSO 6652.49
    n-butyl acetate 2543.77
    n-octanol 753.32
    chloroform 3697.06
    n-propyl acetate 1795.92
    acetic acid 4780.63
    dichloromethane 3758.32
    cyclohexanone 3560.55
    propylene glycol 1976.93
    isopropyl acetate 1425.81
    DMAc 1078.55
    2-ethoxyethanol 3311.81
    isopentanol 3937.57
    n-heptane 569.94
    ethyl formate 1787.82
    1,2-dichloroethane 2851.72
    n-hexanol 3077.64
    2-methoxyethanol 6351.66
    isobutyl acetate 891.07
    tetrachloromethane 814.46
    n-pentyl acetate 962.62
    transcutol 5907.95
    n-heptanol 907.71
    ethylbenzene 254.76
    MIBK 1044.18
    2-propoxyethanol 3367.51
    tert-butanol 6165.96
    MTBE 2870.6
    2-butoxyethanol 1454.25
    propionic acid 2969.37
    o-xylene 280.93
    formic acid 1272.7
    diethyl ether 4177.53
    m-xylene 311.97
    p-xylene 334.45
    chlorobenzene 759.88
    dimethyl carbonate 282.51
    n-octane 130.55
    formamide 1512.31
    cyclopentanone 2864.89
    2-pentanone 2542.42
    anisole 573.31
    cyclopentyl methyl ether 2555.89
    gamma-butyrolactone 2714.0
    1-methoxy-2-propanol 3810.04
    pyridine 2409.35
    3-pentanone 1266.55
    furfural 1837.82
    n-dodecane 62.23
    diethylene glycol 2431.69
    diisopropyl ether 752.07
    tert-amyl alcohol 3454.25
    acetylacetone 1585.38
    n-hexadecane 69.42
    acetophenone 506.5
    methyl propionate 1555.58
    isopentyl acetate 1662.2
    trichloroethylene 3648.52
    n-nonanol 595.03
    cyclohexanol 3891.43
    benzyl alcohol 736.61
    2-ethylhexanol 1555.69
    isooctanol 682.17
    dipropyl ether 2175.37
    1,2-dichlorobenzene 603.71
    ethyl lactate 577.12
    propylene carbonate 1347.65
    n-methylformamide 2160.83
    2-pentanol 3604.23
    n-pentane 740.35
    1-propoxy-2-propanol 2747.61
    1-methoxy-2-propyl acetate 1271.23
    2-(2-methoxypropoxy) propanol 729.02
    mesitylene 210.14
    ε-caprolactone 2545.09
    p-cymene 273.0
    epichlorohydrin 3249.27
    1,1,1-trichloroethane 2017.48
    2-aminoethanol 3204.59
    morpholine-4-carbaldehyde 1942.57
    sulfolane 2491.41
    2,2,4-trimethylpentane 187.48
    2-methyltetrahydrofuran 4396.86
    n-hexyl acetate 1083.48
    isooctane 147.75
    2-(2-butoxyethoxy)ethanol 1365.53
    sec-butyl acetate 913.87
    tert-butyl acetate 1265.94
    decalin 205.65
    glycerin 1856.55
    diglyme 2616.75
    acrylic acid 1757.21
    isopropyl myristate 331.13
    n-butyric acid 5458.29
    acetyl acetate 1080.34
    di(2-ethylhexyl) phthalate 262.96
    ethyl propionate 1083.25
    nitromethane 3965.23
    1,2-diethoxyethane 2287.28
    benzonitrile 874.26
    trioctyl phosphate 243.05
    1-bromopropane 2481.71
    gamma-valerolactone 3304.42
    n-decanol 390.48
    triethyl phosphate 381.47
    4-methyl-2-pentanol 1202.03
    propionitrile 2638.54
    vinylene carbonate 1079.79
    1,1,2-trichlorotrifluoroethane 2486.0
    DMS 498.82
    cumene 191.08
    2-octanol 536.43
    2-hexanone 1619.07
    octyl acetate 418.08
    limonene 621.44
    1,2-dimethoxyethane 3853.63
    ethyl orthosilicate 444.5
    tributyl phosphate 328.69
    diacetone alcohol 1411.3
    N,N-dimethylaniline 333.98
    acrylonitrile 2259.75
    aniline 1011.98
    1,3-propanediol 4519.92
    bromobenzene 694.93
    dibromomethane 2927.16
    1,1,2,2-tetrachloroethane 2957.32
    2-methyl-cyclohexyl acetate 718.29
    tetrabutyl urea 383.8
    diisobutyl methanol 731.86
    2-phenylethanol 762.25
    styrene 376.49
    dioctyl adipate 484.86
    dimethyl sulfate 425.09
    ethyl butyrate 1463.71
    methyl lactate 654.17
    butyl lactate 723.02
    diethyl carbonate 661.49
    propanediol butyl ether 1157.75
    triethyl orthoformate 913.5
    p-tert-butyltoluene 262.14
    methyl 4-tert-butylbenzoate 442.08
    morpholine 6203.26
    tert-butylamine 3922.25
    n-dodecanol 289.68
    dimethoxymethane 1822.15
    ethylene carbonate 1188.1
    cyrene 513.88
    2-ethoxyethyl acetate 994.02
    2-ethylhexyl acetate 1157.87
    1,2,4-trichlorobenzene 647.48
    4-methylpyridine 1655.64
    dibutyl ether 1314.81
    2,6-dimethyl-4-heptanol 731.86
    DEF 2158.97
    dimethyl isosorbide 981.53
    tetrachloroethylene 2448.64
    eugenol 467.1
    triacetin 705.88
    span 80 905.35
    1,4-butanediol 1466.84
    1,1-dichloroethane 2815.1
    2-methyl-1-pentanol 1838.15
    methyl formate 1205.03
    2-methyl-1-butanol 3347.31
    n-decane 130.07
    butyronitrile 3323.96
    3,7-dimethyl-1-octanol 750.72
    1-chlorooctane 444.05
    1-chlorotetradecane 137.48
    n-nonane 150.28
    undecane 83.81
    tert-butylcyclohexane 196.46
    cyclooctane 243.52
    cyclopentanol 3871.02
    tetrahydropyran 6251.74
    tert-amyl methyl ether 1495.98
    2,5,8-trioxanonane 1324.19
    1-hexene 1766.03
    2-isopropoxyethanol 1875.65
    2,2,2-trifluoroethanol 889.21
    methyl butyrate 1842.76

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction