2-Hexadecanol

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  • Identifiers

    CAS number
    14852-31-4

    Molecular formula
    C16H34O

    SMILES
    CCCCCCCCCCCCCCC(C)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 66.17%
    Fatty 65.94%
    Oily 60.5%
    Fruity 60.12%
    Floral 42.96%
    Citrus 37.95%
    Fresh 36.22%
    Clean 32.15%
    Orange 28.44%
    Sweet 28.17%

     

    Flavor
    Waxy 63.33%
    Fatty 41.26%
    Fresh 36.37%
    Fat 36.16%
    Mild 34.16%
    Soapy 32.94%
    Floral 32.21%
    Flower 30.43%
    Oily 30.24%
    Wax 29.22%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    7.2

    pKa est.
    7.97 (neutral)

    Molecular weight
    242.44 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    312°C

    Flash point

    • 142.62 ˚C est.

  • Synonyms

    • 2-Hexadecanol
    • Hexadecan-2-ol
    • Hexadecanol-2
    • EINECS 238-917-5
    • NSC 87605
    • AI3-35278
    • DTXSID80871235
    • RefChem:87270
    • DTXCID60818906
    • 238-917-5
    • FVDRFBGMOWJEOR-UHFFFAOYSA-N
    • 14852-31-4
    • MFCD00004553
    • NSC87605
    • 2-Hexadecanol, 99%
    • Methyl tetradecyl carbinol
    • SCHEMBL259176
    • SCHEMBL336677
    • CHEMBL446956
    • SCHEMBL3620831
    • SCHEMBL28334079
    • CHEBI:185029
    • NSC-87605
    • AKOS009157550
    • SY445036
    • NS00052285
    • G85770
    • 14852-31-4

  • Applications

    2-Hexadecanol (CAS 14852-31-4) is a long-chain fatty alcohol that can serve as an intermediate in organic synthesis and as a component in fragrance formulations, acting as a precursor for fragrance esters. In cosmetics and personal care, it may contribute to texture and feel due to its waxy, long-chain nature and is considered an emollient or thickening aid in various personal care formulas. In industrial manufacturing, it can be used as a solvent or co-solvent for specialty formulations. In coatings and inks, it can function as a waxy additive and lubricating aid to improve processability and gloss. In polymers and plastics, it may be evaluated as a plasticizer or processing aid for certain specialty polymer systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 509.88
    methanol 241.53
    isopropanol 844.51
    water 0.01
    ethyl acetate 1314.84
    n-propanol 688.19
    acetone 975.73
    n-butanol 951.08
    acetonitrile 247.77
    DMF 633.65
    toluene 478.08
    isobutanol 724.67
    1,4-dioxane 1376.48
    methyl acetate 601.28
    THF 3833.74
    2-butanone 1183.62
    n-pentanol 647.19
    sec-butanol 917.04
    n-hexane 1102.94
    ethylene glycol 15.18
    NMP 996.34
    cyclohexane 2154.44
    DMSO 1010.76
    n-butyl acetate 2117.17
    n-octanol 502.34
    chloroform 1892.42
    n-propyl acetate 1467.52
    acetic acid 204.85
    dichloromethane 1740.43
    cyclohexanone 2475.93
    propylene glycol 71.19
    isopropyl acetate 1309.91
    DMAc 759.84
    2-ethoxyethanol 609.06
    isopentanol 1082.77
    n-heptane 1363.95
    ethyl formate 404.36
    1,2-dichloroethane 1481.14
    n-hexanol 943.18
    2-methoxyethanol 703.28
    isobutyl acetate 1046.04
    tetrachloromethane 635.18
    n-pentyl acetate 1424.29
    transcutol 2695.83
    n-heptanol 544.8
    ethylbenzene 407.87
    MIBK 1198.82
    2-propoxyethanol 1054.71
    tert-butanol 1466.72
    MTBE 2136.88
    2-butoxyethanol 875.87
    propionic acid 336.36
    o-xylene 400.34
    formic acid 17.96
    diethyl ether 2022.83
    m-xylene 396.44
    p-xylene 549.5
    chlorobenzene 572.6
    dimethyl carbonate 137.03
    n-octane 316.55
    formamide 35.52
    cyclopentanone 2060.65
    2-pentanone 1525.73
    anisole 573.86
    cyclopentyl methyl ether 2455.04
    gamma-butyrolactone 1517.72
    1-methoxy-2-propanol 929.9
    pyridine 997.93
    3-pentanone 1059.44
    furfural 804.84
    n-dodecane 105.98
    diethylene glycol 263.33
    diisopropyl ether 1008.58
    tert-amyl alcohol 1269.47
    acetylacetone 1029.69
    n-hexadecane 133.56
    acetophenone 590.13
    methyl propionate 725.0
    isopentyl acetate 1961.2
    trichloroethylene 1693.16
    n-nonanol 500.51
    cyclohexanol 1477.29
    benzyl alcohol 328.18
    2-ethylhexanol 1067.73
    isooctanol 620.96
    dipropyl ether 3351.88
    1,2-dichlorobenzene 606.16
    ethyl lactate 370.87
    propylene carbonate 917.05
    n-methylformamide 189.42
    2-pentanol 991.01
    n-pentane 637.91
    1-propoxy-2-propanol 1432.29
    1-methoxy-2-propyl acetate 1250.49
    2-(2-methoxypropoxy) propanol 586.83
    mesitylene 346.69
    ε-caprolactone 1834.38
    p-cymene 465.34
    epichlorohydrin 1657.67
    1,1,1-trichloroethane 1713.11
    2-aminoethanol 88.36
    morpholine-4-carbaldehyde 939.66
    sulfolane 1970.44
    2,2,4-trimethylpentane 275.87
    2-methyltetrahydrofuran 2979.78
    n-hexyl acetate 1378.2
    isooctane 235.9
    2-(2-butoxyethoxy)ethanol 878.81
    sec-butyl acetate 1277.94
    tert-butyl acetate 1655.7
    decalin 500.09
    glycerin 88.9
    diglyme 1848.55
    acrylic acid 146.83
    isopropyl myristate 601.23
    n-butyric acid 1101.9
    acetyl acetate 561.14
    di(2-ethylhexyl) phthalate 291.65
    ethyl propionate 1215.22
    nitromethane 395.68
    1,2-diethoxyethane 2123.94
    benzonitrile 476.24
    trioctyl phosphate 289.18
    1-bromopropane 1731.92
    gamma-valerolactone 1900.31
    n-decanol 346.68
    triethyl phosphate 639.32
    4-methyl-2-pentanol 668.72
    propionitrile 523.9
    vinylene carbonate 516.26
    1,1,2-trichlorotrifluoroethane 916.58
    DMS 466.89
    cumene 330.44
    2-octanol 504.77
    2-hexanone 1398.07
    octyl acetate 609.26
    limonene 1045.2
    1,2-dimethoxyethane 1804.46
    ethyl orthosilicate 729.62
    tributyl phosphate 401.21
    diacetone alcohol 1144.08
    N,N-dimethylaniline 455.91
    acrylonitrile 323.36
    aniline 427.7
    1,3-propanediol 277.26
    bromobenzene 703.3
    dibromomethane 1501.09
    1,1,2,2-tetrachloroethane 2027.49
    2-methyl-cyclohexyl acetate 1137.19
    tetrabutyl urea 536.49
    diisobutyl methanol 837.34
    2-phenylethanol 438.79
    styrene 436.83
    dioctyl adipate 689.8
    dimethyl sulfate 274.82
    ethyl butyrate 1986.55
    methyl lactate 215.07
    butyl lactate 755.0
    diethyl carbonate 888.09
    propanediol butyl ether 493.42
    triethyl orthoformate 1453.4
    p-tert-butyltoluene 465.67
    methyl 4-tert-butylbenzoate 651.16
    morpholine 2060.98
    tert-butylamine 1277.63
    n-dodecanol 261.57
    dimethoxymethane 707.71
    ethylene carbonate 644.89
    cyrene 442.83
    2-ethoxyethyl acetate 1057.76
    2-ethylhexyl acetate 1720.74
    1,2,4-trichlorobenzene 670.46
    4-methylpyridine 994.14
    dibutyl ether 2104.41
    2,6-dimethyl-4-heptanol 837.34
    DEF 1343.76
    dimethyl isosorbide 1113.84
    tetrachloroethylene 1273.93
    eugenol 439.16
    triacetin 887.8
    span 80 647.77
    1,4-butanediol 94.82
    1,1-dichloroethane 1542.27
    2-methyl-1-pentanol 696.37
    methyl formate 119.86
    2-methyl-1-butanol 885.35
    n-decane 285.11
    butyronitrile 870.94
    3,7-dimethyl-1-octanol 712.04
    1-chlorooctane 758.58
    1-chlorotetradecane 244.65
    n-nonane 330.71
    undecane 159.1
    tert-butylcyclohexane 427.13
    cyclooctane 568.44
    cyclopentanol 1183.61
    tetrahydropyran 3619.87
    tert-amyl methyl ether 1526.93
    2,5,8-trioxanonane 1006.77
    1-hexene 1578.2
    2-isopropoxyethanol 667.27
    2,2,2-trifluoroethanol 64.68
    methyl butyrate 1544.54

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction