2'-Fucosyllactose

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  • Identifiers

    CAS number
    41263-94-9

    Molecular formula
    C18H32O15

    SMILES
    C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O[C@@H]2[C@H]([C@H]([C@H](O[C@H]2O[C@H]([C@@H](CO)O)[C@@H]([C@H](C=O)O)O)CO)O)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 76.23%
    Sweet 41.36%
    Caramellic 21.23%
    Alcoholic 20.17%
    Savory 17.87%
    Milky 17.24%
    Cooling 15.78%
    Bitter 15.67%
    Buttery 15.6%
    Clean 15.22%

     

    Flavor
    Sweet 59.32%
    Odorless 58.02%
    Bitter 43.68%
    Sweet-like 34.11%
    Very mild 24.32%
    Bland 24.25%
    Very slight 21.98%
    Cauliflower 21.17%
    Alkaline 20.14%
    Soup 19.94%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -6.1

    pKa est.
    3.17 (weak acid)

    Molecular weight
    488.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    4401°C

    Flash point

    • 283.71 ˚C est.

  • Synonyms

    • 2'-Fucosyllactose
    • 41263-94-9
    • 2'-O-fucosyllactose
    • Lactose, 2'-o-fucosyl-
    • XO2533XO8R
    • 2'-o-l-fucosyl-d-lactose
    • DTXSID40194179
    • (2R,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,3,5,6-tetrahydroxyhexanal
    • (2R,3R,4R,5R)-4-(((2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl)oxy)oxan-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal
    • RefChem:80341
    • DTXCID00116670
    • 807-054-1
    • CHEBI:147155
    • 2'-Fucosyl-D-lactose
    • 2'-Fucosyllactose - Synthetic
    • MFCD00079286
    • (2R,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,3,5,6-tetrahydroxyhexanal
    • CID 170484
    • (2R,3R,4R,5R)-4-(((2S,3R,4S,5R,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal
    • 2'-Fucosyllactose (~90%)
    • Fuc-a-1,2-Gal-b-1,4-Glc
    • 2 inverted exclamation marka-Fucosyl-D-lactose
    • 2/'-FUCOSYLLACTOSE
    • UNII-XO2533XO8R
    • 2-FL
    • orb1296957
    • SCHEMBL2505859
    • 2'-Fucosyllactose - min 90%
    • CHEMBL4297252
    • HWHQUWQCBPAQQH-BWRPKUOHSA-N
    • HY-N9965
    • MSK001232
    • EBC-616958
    • OF06739
    • BS-48262
    • OF137553
    • PD143760
    • 2 inverted exclamation marka-Fucosyllactose
    • CS-0227010
    • E80805
    • Q4596726
    • 6-Deoxy-alpha-L-galactopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->4)-D-glucose
    • D-Glucose, O-6-deoxy-alpha-L-galactopyranosyl-(1-->2)-O-beta-D-galactopyranosyl-(1-->4)-
    • D-Glucose, O-6-deoxy-alpha-L-galactopyranosyl-(1-2)-O-beta-D-galactopyranosyl-(1-4)-
    • O-6-Deoxy-alpha-L-galactopyranosyl-(1-->2)-O-beta-D-galactopyranosyl-(1-->4)-D-glucose
    • (2R,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-2,3,5,6-tetrakis(oxidanyl)hexanal
    • 41263-94-9

  • Applications

    2'-Fucosyllactose (CAS number: 41263-94-9) is a human milk oligosaccharide commonly used as a prebiotic ingredient in infant formula and certain nutritional products to promote the growth of beneficial gut bacteria; it is also evaluated as a functional ingredient in broader food processing, including fortified foods and beverages. In cosmetics and personal care, it is being explored as a bioactive carbohydrate that may support skin microbiome balance and hydration in formulation research. In research and development, it serves as a defined carbohydrate substrate for gut microbiome studies and related fermentation contexts. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 9.44
    methanol 29.43
    isopropanol 1.96
    water 174.37
    ethyl acetate 1.3
    n-propanol 3.51
    acetone 3.55
    n-butanol 2.15
    acetonitrile 1.74
    DMF 85.74
    toluene 0.36
    isobutanol 0.99
    1,4-dioxane 5.38
    methyl acetate 1.43
    THF 5.08
    2-butanone 1.84
    n-pentanol 0.83
    sec-butanol 1.3
    n-hexane 0.04
    ethylene glycol 63.52
    NMP 91.46
    cyclohexane 0.21
    DMSO 302.59
    n-butyl acetate 0.41
    n-octanol 0.72
    chloroform 0.41
    n-propyl acetate 0.41
    acetic acid 59.44
    dichloromethane 0.67
    cyclohexanone 3.6
    propylene glycol 32.99
    isopropyl acetate 0.64
    DMAc 56.54
    2-ethoxyethanol 14.37
    isopentanol 0.8
    n-heptane 0.15
    ethyl formate 2.39
    1,2-dichloroethane 0.77
    n-hexanol 0.75
    2-methoxyethanol 53.97
    isobutyl acetate 0.15
    tetrachloromethane 0.16
    n-pentyl acetate 0.61
    transcutol 19.29
    n-heptanol 0.94
    ethylbenzene 0.12
    MIBK 0.59
    2-propoxyethanol 7.88
    tert-butanol 0.95
    MTBE 0.32
    2-butoxyethanol 5.56
    propionic acid 7.54
    o-xylene 0.36
    formic acid 294.27
    diethyl ether 0.76
    m-xylene 0.26
    p-xylene 0.11
    chlorobenzene 0.15
    dimethyl carbonate 5.34
    n-octane 0.09
    formamide 202.25
    cyclopentanone 6.31
    2-pentanone 1.54
    anisole 0.4
    cyclopentyl methyl ether 1.9
    gamma-butyrolactone 10.33
    1-methoxy-2-propanol 21.55
    pyridine 2.97
    3-pentanone 1.4
    furfural 13.23
    n-dodecane 0.04
    diethylene glycol 27.03
    diisopropyl ether 0.18
    tert-amyl alcohol 0.94
    acetylacetone 4.23
    n-hexadecane 0.05
    acetophenone 0.96
    methyl propionate 2.95
    isopentyl acetate 0.28
    trichloroethylene 1.14
    n-nonanol 0.69
    cyclohexanol 1.89
    benzyl alcohol 1.23
    2-ethylhexanol 0.33
    isooctanol 0.5
    dipropyl ether 0.68
    1,2-dichlorobenzene 0.17
    ethyl lactate 2.37
    propylene carbonate 3.27
    n-methylformamide 42.66
    2-pentanol 0.86
    n-pentane 0.1
    1-propoxy-2-propanol 3.82
    1-methoxy-2-propyl acetate 2.13
    2-(2-methoxypropoxy) propanol 4.65
    mesitylene 0.17
    ε-caprolactone 4.05
    p-cymene 0.16
    epichlorohydrin 4.77
    1,1,1-trichloroethane 0.17
    2-aminoethanol 43.32
    morpholine-4-carbaldehyde 57.59
    sulfolane 47.33
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 1.69
    n-hexyl acetate 0.66
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 7.69
    sec-butyl acetate 0.22
    tert-butyl acetate 0.58
    decalin 0.04
    glycerin 120.41
    diglyme 12.75
    acrylic acid 17.74
    isopropyl myristate 0.23
    n-butyric acid 5.21
    acetyl acetate 1.49
    di(2-ethylhexyl) phthalate 0.56
    ethyl propionate 0.58
    nitromethane 42.91
    1,2-diethoxyethane 1.48
    benzonitrile 0.49
    trioctyl phosphate 0.5
    1-bromopropane 0.24
    gamma-valerolactone 23.97
    n-decanol 0.5
    triethyl phosphate 0.59
    4-methyl-2-pentanol 0.31
    propionitrile 0.71
    vinylene carbonate 3.67
    1,1,2-trichlorotrifluoroethane 22.36
    DMS 1.44
    cumene 0.08
    2-octanol 0.45
    2-hexanone 0.44
    octyl acetate 0.48
    limonene 0.3
    1,2-dimethoxyethane 6.09
    ethyl orthosilicate 0.49
    tributyl phosphate 0.39
    diacetone alcohol 3.59
    N,N-dimethylaniline 0.57
    acrylonitrile 1.95
    aniline 1.35
    1,3-propanediol 27.55
    bromobenzene 0.1
    dibromomethane 0.33
    1,1,2,2-tetrachloroethane 1.07
    2-methyl-cyclohexyl acetate 0.41
    tetrabutyl urea 1.0
    diisobutyl methanol 0.22
    2-phenylethanol 0.88
    styrene 0.13
    dioctyl adipate 0.64
    dimethyl sulfate 18.28
    ethyl butyrate 0.5
    methyl lactate 15.67
    butyl lactate 1.8
    diethyl carbonate 0.37
    propanediol butyl ether 8.4
    triethyl orthoformate 0.65
    p-tert-butyltoluene 0.16
    methyl 4-tert-butylbenzoate 2.0
    morpholine 10.27
    tert-butylamine 0.31
    n-dodecanol 0.36
    dimethoxymethane 15.13
    ethylene carbonate 2.48
    cyrene 11.29
    2-ethoxyethyl acetate 1.79
    2-ethylhexyl acetate 0.22
    1,2,4-trichlorobenzene 0.3
    4-methylpyridine 1.35
    dibutyl ether 0.34
    2,6-dimethyl-4-heptanol 0.22
    DEF 7.24
    dimethyl isosorbide 6.31
    tetrachloroethylene 1.05
    eugenol 2.46
    triacetin 2.39
    span 80 4.69
    1,4-butanediol 8.12
    1,1-dichloroethane 0.24
    2-methyl-1-pentanol 0.4
    methyl formate 22.38
    2-methyl-1-butanol 0.92
    n-decane 0.09
    butyronitrile 0.58
    3,7-dimethyl-1-octanol 0.31
    1-chlorooctane 0.19
    1-chlorotetradecane 0.08
    n-nonane 0.09
    undecane 0.06
    tert-butylcyclohexane 0.02
    cyclooctane 0.12
    cyclopentanol 2.75
    tetrahydropyran 1.62
    tert-amyl methyl ether 0.52
    2,5,8-trioxanonane 10.11
    1-hexene 0.09
    2-isopropoxyethanol 3.91
    2,2,2-trifluoroethanol 32.0
    methyl butyrate 0.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction