2-(Ethylthio)ethanol

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  • Identifiers

    CAS number
    110-77-0

    Molecular formula
    C4H10OS

    SMILES
    CCSCCO

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Sulfurous 85.5%
    Meaty 74.59%
    Onion 61.42%
    Savory 57.4%
    Garlic 54.29%
    Vegetable 51.81%
    Alliaceous 50.96%
    Roasted 45.66%
    Cooked 40.36%
    Tropical 39.55%

     

    Flavor
    Sulfurous 70.71%
    Onion 55.96%
    Vegetable 45.28%
    Meaty 41.43%
    Sulfury 41.26%
    Garlic 36.9%
    Roasted 31.45%
    Potato 31.37%
    Sweet 30.65%
    Cabbage 29.56%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    7.06 (neutral)

    Molecular weight
    106.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Melting point expt.

    • -100 °C

    Boiling point

    • 184.5 °C
    • Boiling point at 28 mm Hg = 99 °C

    Flash point

    • 67.0 ˚C est.

    Solubility expt.

    • Sol in ether, other org solvents
    • Soluble in ethanol, very sol in acetone
    • Practically insoluble or insoluble in water
    • Soluble (in ethanol)

  • Synonyms

    • 2-(ETHYLTHIO)ETHANOL
    • Ethyl 2-hydroxyethyl sulfide
    • 110-77-0
    • Ethanol, 2-(ethylthio)-
    • 2-ethylsulfanylethanol
    • Ethyl thioethanol
    • 2-Hydroxyethyl ethyl sulfide
    • Ethyl 2-hydroxyethyl thioether
    • beta-Hydroxydiethyl sulfide
    • .beta.-Hydroxydiethyl sulfide
    • NSC 57105
    • Ethyl beta-hydroxyethyl sulfide
    • beta-ethylmerkaptoethanol
    • HSDB 5541
    • beta-Ethylmerkaptoethanol [Czech]
    • .beta.-ethylmerkaptoethanol
    • 2-ethylthioethanol
    • EINECS 203-802-0
    • 2-(ethylsulfanyl)ethan-1-ol
    • BRN 1731373
    • 2-ethylmercaptoethanol
    • Ethyl .beta.-hydroxyethyl sulfide
    • .beta.-Ethylthioethanol
    • UNII-6091RQ1378
    • NSC-57105
    • 6091RQ1378
    • DTXSID3059393
    • FEMA NO. 4562
    • EC 203-802-0
    • 2-(ETHYLTHIO)ETHANOL [MI]
    • 2-(ETHYLTHIO)ETHANOL [HSDB]
    • beta-Ethylthioethanol
    • BETA-ETHYLMERKAPTOETHANOL (CZECH)
    • 2-Hydroxydiethyl Sulfide
    • 2-(Ethylsulfanyl)ethanol
    • 2-(ethylmercapto)-ethanol
    • ethyl 2-hydroxyethyl sulphide
    • betaEthylthioethanol
    • 3-Thiapentane-1-ol
    • betaEthylmerkaptoethanol
    • 2-(ethylthio) ethanol
    • 2-(ethylthio)-ethanol
    • 2-ethylmercapto-ethanol
    • Ethanol, 2(ethylthio)
    • 1-hydroxy-3-thiapentane
    • betaHydroxydiethyl sulfide
    • hydroxyethyl ethyl sulphide
    • 2-(ethylthio)ethan-1-ol
    • 2-(Ethylthio)-1-ethanol
    • 2Hydroxyethyl ethyl sulfide
    • Ethyl 2hydroxyethyl sulfide
    • 2-(Ethylsulfanyl)ethanol #
    • SCHEMBL22177
    • 2-hydroxyethyl ethyl sulphide
    • Ethyl 2hydroxyethyl thioether
    • Ethyl betahydroxyethyl sulfide
    • WLN: Q2S2
    • DTXCID6033168
    • NSC57105
    • 2-(ETHYLSULFANYL)-1-ETHANOL
    • MFCD00002909
    • STK523315
    • AKOS000120314
    • NS-01005
    • E0248
    • NS00003100
    • EN300-21383
    • Q27263192
    • 203-802-0

  • Applications

    2-(Ethylthio)ethanol (CAS 110-77-0) is primarily used as an organic synthesis intermediate, particularly as a building block for sulfur-containing thioether compounds. It serves as a precursor for polymers and crosslinkers with thioether functionalities in specialty polymer applications. It can function as a co-solvent or processing aid in industrial manufacturing and as a precursor for surfactants and adhesion promoters in coatings and inks. In cosmetics and personal care, it is sometimes evaluated as a precursor for fragrance-related sulfur-containing compounds. It may be used in cleaning formulations as a solvent or processing aid. In pharmaceutical or agrochemical research, it may be evaluated as a reactive starting material under appropriate controls. All uses are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1177.04
    methanol 1429.77
    isopropanol 794.46
    water 10.82
    ethyl acetate 265.7
    n-propanol 817.69
    acetone 680.63
    n-butanol 656.36
    acetonitrile 354.97
    DMF 751.64
    toluene 99.38
    isobutanol 463.23
    1,4-dioxane 776.68
    methyl acetate 278.7
    THF 1101.89
    2-butanone 357.81
    n-pentanol 321.39
    sec-butanol 476.89
    n-hexane 26.97
    ethylene glycol 451.67
    NMP 581.75
    cyclohexane 70.61
    DMSO 1387.81
    n-butyl acetate 304.77
    n-octanol 166.43
    chloroform 565.13
    n-propyl acetate 179.97
    acetic acid 852.19
    dichloromethane 365.92
    cyclohexanone 710.58
    propylene glycol 434.53
    isopropyl acetate 143.64
    DMAc 296.15
    2-ethoxyethanol 421.08
    isopentanol 344.5
    n-heptane 64.41
    ethyl formate 263.68
    1,2-dichloroethane 258.14
    n-hexanol 504.88
    2-methoxyethanol 896.9
    isobutyl acetate 110.21
    tetrachloromethane 145.46
    n-pentyl acetate 164.56
    transcutol 827.95
    n-heptanol 198.22
    ethylbenzene 42.77
    MIBK 147.05
    2-propoxyethanol 647.47
    tert-butanol 667.33
    MTBE 214.72
    2-butoxyethanol 322.19
    propionic acid 557.4
    o-xylene 69.8
    formic acid 403.15
    diethyl ether 258.05
    m-xylene 78.8
    p-xylene 57.81
    chlorobenzene 172.59
    dimethyl carbonate 70.95
    n-octane 19.33
    formamide 388.88
    cyclopentanone 790.23
    2-pentanone 315.13
    anisole 122.89
    cyclopentyl methyl ether 366.21
    gamma-butyrolactone 729.69
    1-methoxy-2-propanol 554.91
    pyridine 486.91
    3-pentanone 171.86
    furfural 635.85
    n-dodecane 14.37
    diethylene glycol 599.06
    diisopropyl ether 63.24
    tert-amyl alcohol 363.01
    acetylacetone 284.47
    n-hexadecane 15.79
    acetophenone 125.14
    methyl propionate 199.18
    isopentyl acetate 206.94
    trichloroethylene 501.77
    n-nonanol 138.8
    cyclohexanol 488.24
    benzyl alcohol 167.1
    2-ethylhexanol 224.84
    isooctanol 139.84
    dipropyl ether 247.3
    1,2-dichlorobenzene 147.11
    ethyl lactate 115.86
    propylene carbonate 312.35
    n-methylformamide 523.9
    2-pentanol 331.81
    n-pentane 35.44
    1-propoxy-2-propanol 475.94
    1-methoxy-2-propyl acetate 233.5
    2-(2-methoxypropoxy) propanol 217.77
    mesitylene 53.67
    ε-caprolactone 458.8
    p-cymene 63.43
    epichlorohydrin 518.8
    1,1,1-trichloroethane 270.52
    2-aminoethanol 655.18
    morpholine-4-carbaldehyde 652.29
    sulfolane 847.16
    2,2,4-trimethylpentane 16.6
    2-methyltetrahydrofuran 658.32
    n-hexyl acetate 196.53
    isooctane 15.92
    2-(2-butoxyethoxy)ethanol 335.5
    sec-butyl acetate 93.37
    tert-butyl acetate 154.35
    decalin 22.16
    glycerin 535.49
    diglyme 562.99
    acrylic acid 469.27
    isopropyl myristate 81.11
    n-butyric acid 628.23
    acetyl acetate 152.13
    di(2-ethylhexyl) phthalate 88.1
    ethyl propionate 117.15
    nitromethane 738.73
    1,2-diethoxyethane 258.29
    benzonitrile 227.48
    trioctyl phosphate 79.61
    1-bromopropane 163.5
    gamma-valerolactone 851.39
    n-decanol 103.57
    triethyl phosphate 76.52
    4-methyl-2-pentanol 131.94
    propionitrile 303.28
    vinylene carbonate 303.26
    1,1,2-trichlorotrifluoroethane 508.84
    DMS 115.17
    cumene 37.75
    2-octanol 119.62
    2-hexanone 191.66
    octyl acetate 110.43
    limonene 118.33
    1,2-dimethoxyethane 480.88
    ethyl orthosilicate 77.87
    tributyl phosphate 85.66
    diacetone alcohol 275.12
    N,N-dimethylaniline 87.25
    acrylonitrile 373.09
    aniline 218.12
    1,3-propanediol 770.92
    bromobenzene 138.74
    dibromomethane 272.21
    1,1,2,2-tetrachloroethane 433.61
    2-methyl-cyclohexyl acetate 138.29
    tetrabutyl urea 120.09
    diisobutyl methanol 115.48
    2-phenylethanol 208.67
    styrene 58.16
    dioctyl adipate 118.5
    dimethyl sulfate 140.07
    ethyl butyrate 178.17
    methyl lactate 170.46
    butyl lactate 162.13
    diethyl carbonate 100.22
    propanediol butyl ether 306.05
    triethyl orthoformate 131.47
    p-tert-butyltoluene 66.12
    methyl 4-tert-butylbenzoate 154.23
    morpholine 887.77
    tert-butylamine 333.3
    n-dodecanol 82.06
    dimethoxymethane 330.67
    ethylene carbonate 254.66
    cyrene 197.11
    2-ethoxyethyl acetate 182.74
    2-ethylhexyl acetate 155.88
    1,2,4-trichlorobenzene 172.36
    4-methylpyridine 348.32
    dibutyl ether 143.3
    2,6-dimethyl-4-heptanol 115.48
    DEF 297.13
    dimethyl isosorbide 330.06
    tetrachloroethylene 359.57
    eugenol 184.06
    triacetin 159.24
    span 80 269.12
    1,4-butanediol 264.86
    1,1-dichloroethane 296.38
    2-methyl-1-pentanol 182.97
    methyl formate 306.1
    2-methyl-1-butanol 330.67
    n-decane 24.52
    butyronitrile 363.82
    3,7-dimethyl-1-octanol 138.05
    1-chlorooctane 84.46
    1-chlorotetradecane 34.47
    n-nonane 24.9
    undecane 17.9
    tert-butylcyclohexane 23.47
    cyclooctane 21.49
    cyclopentanol 645.81
    tetrahydropyran 758.79
    tert-amyl methyl ether 142.46
    2,5,8-trioxanonane 400.39
    1-hexene 87.55
    2-isopropoxyethanol 256.38
    2,2,2-trifluoroethanol 248.52
    methyl butyrate 188.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction