2-Ethyl-6-methoxyphenol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    90534-46-6

    Molecular formula
    C9H12O2

    SMILES
    CCC1=C(C(=CC=C1)OC)O

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 86.54%
    Sweet 77.5%
    Smoky 76.01%
    Spicy 73.11%
    Vanilla 65.54%
    Medicinal 59.84%
    Woody 58.04%
    Burnt 53.09%
    Clove 46.94%
    Balsamic 44.47%

     

    Flavor
    Phenolic 80.89%
    Smoky 66.23%
    Sweet 61.92%
    Spicy 58.76%
    Medicinal 57.51%
    Spice 56.19%
    Bacon 55.73%
    Clove 55.57%
    Vanilla 53.96%
    Smoke 52.15%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    9.68 (weak base)

    Molecular weight
    152.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    242°C

    Flash point

    • 95.21 ˚C est.

  • Synonyms

    • 2-ethyl-6-methoxyphenol
    • 90534-46-6
    • 6-Ethylguaiacol
    • 6-Ethyl-2-methoxyphenol
    • L5S7PJR6D7
    • 2-METHOXY-6-ETHYLPHENOL
    • 3-ETHYL-2-HYDROXYANISOLE
    • DTXSID00920335
    • RefChem:86923
    • DTXCID801349247
    • Phenol, 2-ethyl-6-methoxy-
    • MFCD16997784
    • 2-ethyl-6-methoxy-phenol
    • UNII-L5S7PJR6D7
    • SCHEMBL9576160
    • RSZPVOABCKCPKY-UHFFFAOYSA-N
    • AKOS024049866
    • MB24092
    • AS-50067
    • O10769
    • 90534-46-6

  • Applications

    2-Ethyl-6-methoxyphenol (CAS number: 90534-46-6) is primarily used as an odorant/fragrance ingredient in perfumery and cosmetics, contributing woody, phenolic notes and aiding fragrance longevity. It is also employed as an aroma/flavor intermediate for formulation of flavorings in the food and beverage sector, subject to regulatory approvals. In the plastics and coatings sector, the compound may function as an antioxidant or stabilizer to improve the durability of polymer systems and coatings. It serves as a chemical intermediate in the synthesis of other fragrance, flavor, or industrial compounds. Additionally, it may be used as a fragrance component in cleaning products to impart desirable scents, within formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1345.19
    methanol 1565.83
    isopropanol 737.29
    water 5.27
    ethyl acetate 841.97
    n-propanol 854.3
    acetone 1308.15
    n-butanol 601.01
    acetonitrile 1909.79
    DMF 1271.91
    toluene 220.47
    isobutanol 487.83
    1,4-dioxane 2312.25
    methyl acetate 1191.44
    THF 1560.8
    2-butanone 846.44
    n-pentanol 473.72
    sec-butanol 541.3
    n-hexane 53.87
    ethylene glycol 457.68
    NMP 619.84
    cyclohexane 141.86
    DMSO 1661.73
    n-butyl acetate 640.4
    n-octanol 320.25
    chloroform 2613.83
    n-propyl acetate 653.54
    acetic acid 1193.22
    dichloromethane 3377.78
    cyclohexanone 961.36
    propylene glycol 305.3
    isopropyl acetate 346.76
    DMAc 491.23
    2-ethoxyethanol 949.08
    isopentanol 368.76
    n-heptane 78.53
    ethyl formate 1154.92
    1,2-dichloroethane 1874.43
    n-hexanol 488.28
    2-methoxyethanol 1350.69
    isobutyl acetate 301.64
    tetrachloromethane 514.63
    n-pentyl acetate 362.5
    transcutol 1194.84
    n-heptanol 295.66
    ethylbenzene 174.33
    MIBK 272.2
    2-propoxyethanol 782.16
    tert-butanol 840.07
    MTBE 531.79
    2-butoxyethanol 497.77
    propionic acid 796.24
    o-xylene 157.36
    formic acid 562.23
    diethyl ether 744.81
    m-xylene 162.82
    p-xylene 233.62
    chlorobenzene 565.23
    dimethyl carbonate 328.96
    n-octane 50.11
    formamide 1170.08
    cyclopentanone 1081.61
    2-pentanone 520.39
    anisole 452.86
    cyclopentyl methyl ether 429.64
    gamma-butyrolactone 1537.28
    1-methoxy-2-propanol 679.65
    pyridine 1158.3
    3-pentanone 375.9
    furfural 1204.86
    n-dodecane 43.34
    diethylene glycol 649.03
    diisopropyl ether 157.05
    tert-amyl alcohol 522.85
    acetylacetone 610.96
    n-hexadecane 49.5
    acetophenone 378.83
    methyl propionate 558.69
    isopentyl acetate 422.66
    trichloroethylene 2780.66
    n-nonanol 262.65
    cyclohexanol 397.73
    benzyl alcohol 371.47
    2-ethylhexanol 280.79
    isooctanol 232.85
    dipropyl ether 359.38
    1,2-dichlorobenzene 536.64
    ethyl lactate 272.32
    propylene carbonate 798.37
    n-methylformamide 1365.35
    2-pentanol 317.06
    n-pentane 58.81
    1-propoxy-2-propanol 493.84
    1-methoxy-2-propyl acetate 382.62
    2-(2-methoxypropoxy) propanol 309.46
    mesitylene 125.65
    ε-caprolactone 810.9
    p-cymene 143.42
    epichlorohydrin 1826.16
    1,1,1-trichloroethane 1356.9
    2-aminoethanol 646.81
    morpholine-4-carbaldehyde 969.13
    sulfolane 1355.21
    2,2,4-trimethylpentane 36.79
    2-methyltetrahydrofuran 894.4
    n-hexyl acetate 457.8
    isooctane 34.8
    2-(2-butoxyethoxy)ethanol 496.26
    sec-butyl acetate 277.92
    tert-butyl acetate 345.25
    decalin 60.39
    glycerin 399.3
    diglyme 1083.85
    acrylic acid 707.04
    isopropyl myristate 188.46
    n-butyric acid 839.26
    acetyl acetate 458.75
    di(2-ethylhexyl) phthalate 149.13
    ethyl propionate 415.35
    nitromethane 2568.5
    1,2-diethoxyethane 618.36
    benzonitrile 618.6
    trioctyl phosphate 138.71
    1-bromopropane 786.34
    gamma-valerolactone 1305.91
    n-decanol 198.86
    triethyl phosphate 184.49
    4-methyl-2-pentanol 162.67
    propionitrile 1076.33
    vinylene carbonate 930.72
    1,1,2-trichlorotrifluoroethane 951.21
    DMS 324.57
    cumene 133.43
    2-octanol 221.37
    2-hexanone 475.62
    octyl acetate 252.29
    limonene 187.31
    1,2-dimethoxyethane 1433.23
    ethyl orthosilicate 170.33
    tributyl phosphate 157.8
    diacetone alcohol 402.2
    N,N-dimethylaniline 241.54
    acrylonitrile 1536.49
    aniline 354.61
    1,3-propanediol 784.67
    bromobenzene 597.17
    dibromomethane 2135.86
    1,1,2,2-tetrachloroethane 1691.87
    2-methyl-cyclohexyl acetate 254.52
    tetrabutyl urea 192.57
    diisobutyl methanol 163.64
    2-phenylethanol 345.06
    styrene 245.55
    dioctyl adipate 245.33
    dimethyl sulfate 413.81
    ethyl butyrate 455.37
    methyl lactate 276.87
    butyl lactate 252.94
    diethyl carbonate 346.88
    propanediol butyl ether 383.25
    triethyl orthoformate 275.98
    p-tert-butyltoluene 134.17
    methyl 4-tert-butylbenzoate 296.36
    morpholine 1841.12
    tert-butylamine 458.84
    n-dodecanol 154.0
    dimethoxymethane 879.8
    ethylene carbonate 794.51
    cyrene 290.21
    2-ethoxyethyl acetate 446.25
    2-ethylhexyl acetate 328.54
    1,2,4-trichlorobenzene 538.68
    4-methylpyridine 709.24
    dibutyl ether 327.96
    2,6-dimethyl-4-heptanol 163.64
    DEF 543.31
    dimethyl isosorbide 473.71
    tetrachloroethylene 1321.54
    eugenol 327.46
    triacetin 358.09
    span 80 273.35
    1,4-butanediol 370.4
    1,1-dichloroethane 1536.43
    2-methyl-1-pentanol 307.58
    methyl formate 1311.96
    2-methyl-1-butanol 345.18
    n-decane 68.03
    butyronitrile 918.13
    3,7-dimethyl-1-octanol 215.64
    1-chlorooctane 235.02
    1-chlorotetradecane 97.14
    n-nonane 69.86
    undecane 53.1
    tert-butylcyclohexane 55.74
    cyclooctane 47.29
    cyclopentanol 505.56
    tetrahydropyran 1203.18
    tert-amyl methyl ether 294.07
    2,5,8-trioxanonane 609.97
    1-hexene 185.27
    2-isopropoxyethanol 539.03
    2,2,2-trifluoroethanol 420.53
    methyl butyrate 614.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction