2-Ethoxypropanal

Overview IFRA Request a quote

  • Identifiers

    CAS number
    5393-69-1

    Molecular formula
    C5H10O2

    SMILES
    CCOC(C)C=O

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 62.99%
    Ethereal 62.61%
    Green 52.09%
    Pungent 43.84%
    Nutty 40.94%
    Alcoholic 39.61%
    Sweet 39.57%
    Fermented 36.37%
    Fresh 35.25%
    Sharp 34.09%

     

    Flavor
    Pungent 44.54%
    Ethereal 42.8%
    Musty 37.18%
    Vegetable 37.08%
    Green 37.04%
    Earthy 35.22%
    Nutty 34.93%
    Fatty 30.78%
    Fruity 30.71%
    Sweet 29.36%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.4

    pKa est.
    6.46 (neutral)

    Molecular weight
    102.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    111°C

    Flash point

    • 23.29 ˚C est.

  • Synonyms

    • 2-ethoxypropanal
    • 5393-69-1
    • DTXSID30277905
    • RefChem:260407
    • DTXCID10229063
    • 858-180-9
    • NSC4770
    • SCHEMBL618012
    • SCHEMBL945319
    • SCHEMBL1562985
    • SCHEMBL3026953
    • SCHEMBL27276537
    • NSC-4770
    • AKOS022632609
    • DA-26268
    • DB-370071
    • EN300-1725405
    • 5393-69-1

  • Applications

    2-Ethoxypropanal (CAS 5393-69-1) is primarily used as a reactive aldehyde building block in organic synthesis and as a fragrance/odorant intermediate. In industry, it can serve as a precursor for specialty chemicals used in fragrance and flavor applications, enabling the synthesis of ether-containing aldehydes and related aroma compounds. It may be evaluated for use in coatings, inks, and adhesives as a reactive aldehyde component or fragrance carrier, and in cosmetics, personal care, and household products where controlled aroma notes are desirable, subject to regulatory limits. It can also function as a laboratory or pilot-scale intermediate in polymer chemistry and other industrial manufacturing contexts, where it participates in route development for functionalized propanal derivatives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 306.27
    methanol 587.62
    isopropanol 169.21
    water 13.08
    ethyl acetate 173.97
    n-propanol 196.77
    acetone 219.32
    n-butanol 177.51
    acetonitrile 351.7
    DMF 294.31
    toluene 64.11
    isobutanol 127.92
    1,4-dioxane 368.7
    methyl acetate 200.43
    THF 341.62
    2-butanone 167.27
    n-pentanol 116.67
    sec-butanol 139.1
    n-hexane 25.86
    ethylene glycol 140.92
    NMP 355.07
    cyclohexane 45.87
    DMSO 444.98
    n-butyl acetate 135.76
    n-octanol 56.21
    chloroform 482.41
    n-propyl acetate 87.99
    acetic acid 561.28
    dichloromethane 557.97
    cyclohexanone 253.66
    propylene glycol 94.47
    isopropyl acetate 71.08
    DMAc 251.36
    2-ethoxyethanol 205.35
    isopentanol 128.9
    n-heptane 22.22
    ethyl formate 155.07
    1,2-dichloroethane 289.01
    n-hexanol 124.51
    2-methoxyethanol 368.9
    isobutyl acetate 51.59
    tetrachloromethane 120.52
    n-pentyl acetate 67.1
    transcutol 581.11
    n-heptanol 45.4
    ethylbenzene 37.85
    MIBK 55.83
    2-propoxyethanol 207.37
    tert-butanol 194.71
    MTBE 126.46
    2-butoxyethanol 92.31
    propionic acid 230.75
    o-xylene 55.21
    formic acid 342.17
    diethyl ether 155.65
    m-xylene 41.8
    p-xylene 55.37
    chlorobenzene 136.87
    dimethyl carbonate 39.34
    n-octane 8.02
    formamide 279.09
    cyclopentanone 255.15
    2-pentanone 111.75
    anisole 97.36
    cyclopentyl methyl ether 133.76
    gamma-butyrolactone 334.3
    1-methoxy-2-propanol 168.22
    pyridine 275.0
    3-pentanone 93.52
    furfural 383.29
    n-dodecane 7.21
    diethylene glycol 234.3
    diisopropyl ether 31.85
    tert-amyl alcohol 155.03
    acetylacetone 130.1
    n-hexadecane 7.95
    acetophenone 90.08
    methyl propionate 114.36
    isopentyl acetate 105.35
    trichloroethylene 464.93
    n-nonanol 48.51
    cyclohexanol 163.28
    benzyl alcohol 103.78
    2-ethylhexanol 76.1
    isooctanol 36.88
    dipropyl ether 74.58
    1,2-dichlorobenzene 133.08
    ethyl lactate 55.29
    propylene carbonate 162.4
    n-methylformamide 223.05
    2-pentanol 89.71
    n-pentane 25.68
    1-propoxy-2-propanol 127.45
    1-methoxy-2-propyl acetate 107.41
    2-(2-methoxypropoxy) propanol 131.05
    mesitylene 28.65
    ε-caprolactone 246.15
    p-cymene 39.99
    epichlorohydrin 323.96
    1,1,1-trichloroethane 232.41
    2-aminoethanol 173.21
    morpholine-4-carbaldehyde 353.02
    sulfolane 356.57
    2,2,4-trimethylpentane 15.22
    2-methyltetrahydrofuran 279.47
    n-hexyl acetate 99.35
    isooctane 7.82
    2-(2-butoxyethoxy)ethanol 157.53
    sec-butyl acetate 56.3
    tert-butyl acetate 70.71
    decalin 20.45
    glycerin 154.3
    diglyme 278.5
    acrylic acid 236.5
    isopropyl myristate 42.26
    n-butyric acid 244.59
    acetyl acetate 128.95
    di(2-ethylhexyl) phthalate 52.55
    ethyl propionate 80.48
    nitromethane 551.49
    1,2-diethoxyethane 167.4
    benzonitrile 163.23
    trioctyl phosphate 33.29
    1-bromopropane 164.1
    gamma-valerolactone 346.35
    n-decanol 35.73
    triethyl phosphate 57.55
    4-methyl-2-pentanol 45.72
    propionitrile 205.9
    vinylene carbonate 167.27
    1,1,2-trichlorotrifluoroethane 299.84
    DMS 97.11
    cumene 33.48
    2-octanol 32.1
    2-hexanone 87.5
    octyl acetate 52.39
    limonene 64.17
    1,2-dimethoxyethane 302.31
    ethyl orthosilicate 54.42
    tributyl phosphate 49.47
    diacetone alcohol 94.6
    N,N-dimethylaniline 71.0
    acrylonitrile 254.14
    aniline 126.94
    1,3-propanediol 213.83
    bromobenzene 129.34
    dibromomethane 337.53
    1,1,2,2-tetrachloroethane 334.25
    2-methyl-cyclohexyl acetate 78.17
    tetrabutyl urea 63.53
    diisobutyl methanol 44.02
    2-phenylethanol 95.38
    styrene 54.3
    dioctyl adipate 74.36
    dimethyl sulfate 78.51
    ethyl butyrate 95.98
    methyl lactate 71.6
    butyl lactate 62.36
    diethyl carbonate 73.1
    propanediol butyl ether 91.2
    triethyl orthoformate 69.94
    p-tert-butyltoluene 36.8
    methyl 4-tert-butylbenzoate 81.1
    morpholine 384.71
    tert-butylamine 134.19
    n-dodecanol 28.52
    dimethoxymethane 134.49
    ethylene carbonate 131.52
    cyrene 115.32
    2-ethoxyethyl acetate 106.95
    2-ethylhexyl acetate 85.56
    1,2,4-trichlorobenzene 161.22
    4-methylpyridine 216.09
    dibutyl ether 71.5
    2,6-dimethyl-4-heptanol 44.02
    DEF 173.17
    dimethyl isosorbide 201.56
    tetrachloroethylene 282.95
    eugenol 91.61
    triacetin 117.65
    span 80 106.66
    1,4-butanediol 93.23
    1,1-dichloroethane 244.34
    2-methyl-1-pentanol 102.75
    methyl formate 160.87
    2-methyl-1-butanol 125.4
    n-decane 11.54
    butyronitrile 199.28
    3,7-dimethyl-1-octanol 64.77
    1-chlorooctane 42.5
    1-chlorotetradecane 18.68
    n-nonane 11.82
    undecane 8.73
    tert-butylcyclohexane 18.63
    cyclooctane 13.78
    cyclopentanol 173.5
    tetrahydropyran 283.58
    tert-amyl methyl ether 98.83
    2,5,8-trioxanonane 221.99
    1-hexene 67.85
    2-isopropoxyethanol 116.91
    2,2,2-trifluoroethanol 173.62
    methyl butyrate 112.46

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction