2-Ethoxyphenol

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  • Identifiers

    CAS number
    94-71-3

    Molecular formula
    C8H10O2

    SMILES
    CCOC1=CC=CC=C1O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Phenolic 85.94%
    Sweet 84.58%
    Vanilla 79.89%
    Smoky 71.96%
    Spicy 68.11%
    Woody 57.41%
    Medicinal 55.42%
    Balsamic 47.97%
    Burnt 47.28%
    Clove 47.09%

     

    Flavor
    Sweet 81.64%
    Phenolic 76.15%
    Vanilla 66.89%
    Smoky 59.92%
    Spicy 57.63%
    Woody 55.21%
    Powdery 53.76%
    Clove 53.46%
    Spice 51.43%
    Medicinal 49.55%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.7

    pKa est.
    8.88 (weak base)

    Molecular weight
    138.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    213°C

    Flash point

    • 90.16 ˚C est.

  • Synonyms

    • 2-Ethoxyphenol
    • 94-71-3
    • Guaethol
    • o-Ethoxyphenol
    • Phenol, 2-ethoxy-
    • Guethol
    • Pyrocatechol monoethyl ether
    • 2-Ethyloxyphenol
    • Guaiethol
    • Catechol monoethyl ether
    • Phenol, o-ethoxy-
    • 1-hydroxy-2-ethoxybenzene
    • UNII-878IW8P9PW
    • MFCD00002187
    • 878IW8P9PW
    • DTXSID2042276
    • NSC 1809
    • NSC-1809
    • EINECS 202-358-5
    • DTXCID0022276
    • CHEBI:141701
    • EC 202-358-5
    • oEthoxyphenol
    • 2Ethyloxyphenol
    • 2-ethoxylphenol
    • o-ethoxy phenol
    • Phenol, oethoxy
    • 2-ethoxy phenol
    • 2-ethoxy-phenol
    • Phenol, 2ethoxy
    • 2-Ethoxyphenol, 98%
    • 1,2-Benzenediol,ethyl-
    • Phenol, oethoxy (8CI)
    • GUETHOL [WHO-DD]
    • SCHEMBL28519
    • CHEMBL225436
    • NSC1809
    • Tox21_301383
    • AKOS000120135
    • GS-3119
    • HY-W022036
    • CAS-94-71-3
    • NCGC00255986-01
    • DB-021026
    • CS-0040351
    • E0230
    • NS00004396
    • EN300-20727
    • D72674
    • Q21547070
    • Z104480244

  • Applications

    2-Ethoxyphenol (CAS 94-71-3) is primarily used as an organic synthesis intermediate, notably for the production of fragrance components and dyes/pigments. It also serves as a precursor for compounds used in polymer materials and plastics, and acts as a building block in formulations for coatings and inks, as well as in specialized chemical applications and development research.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1068.74
    methanol 1417.75
    isopropanol 688.02
    water 4.91
    ethyl acetate 726.98
    n-propanol 653.19
    acetone 1368.38
    n-butanol 515.2
    acetonitrile 1425.29
    DMF 1308.71
    toluene 226.7
    isobutanol 421.29
    1,4-dioxane 1389.0
    methyl acetate 988.7
    THF 1249.12
    2-butanone 843.04
    n-pentanol 412.21
    sec-butanol 503.63
    n-hexane 110.75
    ethylene glycol 403.64
    NMP 751.27
    cyclohexane 182.45
    DMSO 2376.26
    n-butyl acetate 774.02
    n-octanol 365.31
    chloroform 1902.53
    n-propyl acetate 677.74
    acetic acid 944.96
    dichloromethane 2859.2
    cyclohexanone 845.17
    propylene glycol 281.61
    isopropyl acetate 323.49
    DMAc 811.84
    2-ethoxyethanol 744.71
    isopentanol 344.1
    n-heptane 157.17
    ethyl formate 823.58
    1,2-dichloroethane 1670.55
    n-hexanol 474.37
    2-methoxyethanol 1044.76
    isobutyl acetate 310.42
    tetrachloromethane 380.03
    n-pentyl acetate 378.54
    transcutol 1272.0
    n-heptanol 267.16
    ethylbenzene 212.0
    MIBK 298.57
    2-propoxyethanol 692.53
    tert-butanol 708.98
    MTBE 494.05
    2-butoxyethanol 422.69
    propionic acid 646.33
    o-xylene 202.74
    formic acid 317.76
    diethyl ether 693.98
    m-xylene 181.27
    p-xylene 294.06
    chlorobenzene 492.03
    dimethyl carbonate 352.46
    n-octane 81.14
    formamide 686.6
    cyclopentanone 1038.97
    2-pentanone 581.45
    anisole 472.83
    cyclopentyl methyl ether 430.01
    gamma-butyrolactone 1278.46
    1-methoxy-2-propanol 600.59
    pyridine 876.8
    3-pentanone 477.03
    furfural 990.29
    n-dodecane 71.96
    diethylene glycol 599.16
    diisopropyl ether 180.66
    tert-amyl alcohol 525.85
    acetylacetone 655.85
    n-hexadecane 78.16
    acetophenone 432.97
    methyl propionate 579.56
    isopentyl acetate 484.23
    trichloroethylene 2233.94
    n-nonanol 293.12
    cyclohexanol 379.52
    benzyl alcohol 330.29
    2-ethylhexanol 319.63
    isooctanol 215.32
    dipropyl ether 522.34
    1,2-dichlorobenzene 500.08
    ethyl lactate 297.51
    propylene carbonate 715.8
    n-methylformamide 882.95
    2-pentanol 323.21
    n-pentane 110.33
    1-propoxy-2-propanol 524.23
    1-methoxy-2-propyl acetate 446.23
    2-(2-methoxypropoxy) propanol 379.73
    mesitylene 149.68
    ε-caprolactone 707.24
    p-cymene 194.17
    epichlorohydrin 1418.36
    1,1,1-trichloroethane 1083.44
    2-aminoethanol 463.06
    morpholine-4-carbaldehyde 904.29
    sulfolane 1414.92
    2,2,4-trimethylpentane 58.93
    2-methyltetrahydrofuran 734.81
    n-hexyl acetate 560.69
    isooctane 49.58
    2-(2-butoxyethoxy)ethanol 534.55
    sec-butyl acetate 298.86
    tert-butyl acetate 337.67
    decalin 95.01
    glycerin 363.74
    diglyme 1091.85
    acrylic acid 553.23
    isopropyl myristate 244.65
    n-butyric acid 660.86
    acetyl acetate 420.73
    di(2-ethylhexyl) phthalate 173.24
    ethyl propionate 492.22
    nitromethane 1864.06
    1,2-diethoxyethane 631.46
    benzonitrile 567.69
    trioctyl phosphate 164.34
    1-bromopropane 771.83
    gamma-valerolactone 1009.18
    n-decanol 232.95
    triethyl phosphate 232.49
    4-methyl-2-pentanol 164.53
    propionitrile 844.36
    vinylene carbonate 734.24
    1,1,2-trichlorotrifluoroethane 789.85
    DMS 401.59
    cumene 165.8
    2-octanol 224.64
    2-hexanone 549.03
    octyl acetate 310.73
    limonene 269.83
    1,2-dimethoxyethane 1369.69
    ethyl orthosilicate 211.26
    tributyl phosphate 209.72
    diacetone alcohol 376.57
    N,N-dimethylaniline 300.31
    acrylonitrile 1095.57
    aniline 301.2
    1,3-propanediol 575.13
    bromobenzene 579.49
    dibromomethane 1810.19
    1,1,2,2-tetrachloroethane 1520.65
    2-methyl-cyclohexyl acetate 308.65
    tetrabutyl urea 267.91
    diisobutyl methanol 207.66
    2-phenylethanol 335.0
    styrene 294.1
    dioctyl adipate 310.76
    dimethyl sulfate 517.32
    ethyl butyrate 589.51
    methyl lactate 303.8
    butyl lactate 288.33
    diethyl carbonate 437.64
    propanediol butyl ether 386.03
    triethyl orthoformate 331.92
    p-tert-butyltoluene 175.43
    methyl 4-tert-butylbenzoate 332.23
    morpholine 1098.55
    tert-butylamine 463.63
    n-dodecanol 195.91
    dimethoxymethane 834.97
    ethylene carbonate 622.85
    cyrene 303.24
    2-ethoxyethyl acetate 448.93
    2-ethylhexyl acetate 383.41
    1,2,4-trichlorobenzene 507.67
    4-methylpyridine 668.87
    dibutyl ether 458.43
    2,6-dimethyl-4-heptanol 207.66
    DEF 705.63
    dimethyl isosorbide 557.75
    tetrachloroethylene 1114.06
    eugenol 348.19
    triacetin 438.57
    span 80 321.55
    1,4-butanediol 315.16
    1,1-dichloroethane 1307.52
    2-methyl-1-pentanol 300.57
    methyl formate 916.29
    2-methyl-1-butanol 342.39
    n-decane 103.65
    butyronitrile 762.01
    3,7-dimethyl-1-octanol 276.4
    1-chlorooctane 309.44
    1-chlorotetradecane 143.65
    n-nonane 112.46
    undecane 83.29
    tert-butylcyclohexane 84.99
    cyclooctane 71.36
    cyclopentanol 470.16
    tetrahydropyran 873.15
    tert-amyl methyl ether 345.7
    2,5,8-trioxanonane 722.33
    1-hexene 287.4
    2-isopropoxyethanol 469.07
    2,2,2-trifluoroethanol 297.54
    methyl butyrate 737.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction