2-(Ethoxymethyl)phenol

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  • Identifiers

    CAS number
    20920-83-6

    Molecular formula
    C9H12O2

    SMILES
    CCOCC1=CC=CC=C1O

  • Odor profile

    Fragrance
    Sweet 90.98%
    Vanilla 64.2%
    Phenolic 62.72%
    Anisic 51.93%
    Aromatic 49.49%
    Spicy 43.41%
    Almond 39.27%
    Smoky 39.25%
    Floral 38.64%
    Medicinal 37.47%

     

    Flavor
    Sweet 78.5%
    Floral 54.85%
    Spicy 52.76%
    Fruity 47.58%
    Powdery 41.21%
    Phenolic 40.36%
    Vanilla 39.23%
    Chocolate 35.4%
    Flower 32.41%
    Smoky 31.91%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.1

    pKa est.
    8.15 (weak base)

    Molecular weight
    152.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point

    • 111.00 to 113.00 °C. @ 20.00 mm Hg

    Flash point

    • 103.6 ˚C est.

    Solubility expt.

    • slightly
    • slightly soluble in water; soluble in oils
    • miscible (in ethanol)

  • Synonyms

    • 2-(Ethoxymethyl)phenol
    • 20920-83-6
    • Phenol, 2-(ethoxymethyl)-
    • o-(Ethoxymethyl)phenol
    • FEMA No. 3485
    • alpha-Ethoxy-O-cresol
    • .alpha.-Ethoxy-o-cresol
    • Z4A6NG7L1F
    • alpha-ethoxy-ortho-cresol
    • O-Cresol, alpha-ethoxy-
    • UNII-Z4A6NG7L1F
    • O-Hydroxybenzyl ethyl ether
    • Hydroxybenzyl ethyl ether, o-
    • o-(ethoxymethyl) phenol
    • DTXSID0066664
    • ETHYL 2-HYDROXYBENZYL ETHER
    • .ALPHA.-ETHOXY-ORTHO-CRESOL
    • O-CRESOL, .ALPHA.-ETHOXY-
    • 2-(ETHOXYMETHYL)PHENOL [FHFI]
    • Athyl-o-oxybenzylather
    • 2-(Ethoxymethyl)-Phenol
    • 2-(Ethoxymethyl)phenol, 9CI
    • SCHEMBL1245021
    • DTXCID7036400
    • FEMA 3485
    • CHEBI:179253
    • GNNUWFUVNWRCEO-UHFFFAOYSA-N
    • NS00121658
    • Q27294980

  • Applications

    2-(Ethoxymethyl)phenol is primarily used as a chemical intermediate in the synthesis of specialty compounds, including fragrance ingredients, dyes, and polymer additives. It can serve as a fragrance or odorant precursor in perfumery and related industries, and may function as an antioxidant or stabilizer in polymer formulations, coatings, and inks, as well as a reactive additive or crosslinking modifier in coatings and adhesives. It is also evaluated as a building block for other specialty chemicals in industrial manufacturing, with applications governed by formulation needs and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1423.7
    methanol 892.18
    isopropanol 1056.52
    water 2.34
    ethyl acetate 503.72
    n-propanol 996.2
    acetone 476.52
    n-butanol 756.09
    acetonitrile 823.49
    DMF 526.1
    toluene 119.37
    isobutanol 604.36
    1,4-dioxane 1184.79
    methyl acetate 524.63
    THF 810.77
    2-butanone 400.77
    n-pentanol 406.95
    sec-butanol 676.03
    n-hexane 22.42
    ethylene glycol 328.91
    NMP 237.4
    cyclohexane 69.98
    DMSO 1093.17
    n-butyl acetate 277.02
    n-octanol 161.36
    chloroform 1324.46
    n-propyl acetate 243.93
    acetic acid 808.92
    dichloromethane 1245.28
    cyclohexanone 456.08
    propylene glycol 548.28
    isopropyl acetate 176.59
    DMAc 369.49
    2-ethoxyethanol 510.72
    isopentanol 431.24
    n-heptane 32.92
    ethyl formate 406.87
    1,2-dichloroethane 671.52
    n-hexanol 406.44
    2-methoxyethanol 929.44
    isobutyl acetate 141.7
    tetrachloromethane 147.0
    n-pentyl acetate 120.6
    transcutol 1004.62
    n-heptanol 155.51
    ethylbenzene 74.33
    MIBK 151.22
    2-propoxyethanol 478.93
    tert-butanol 1004.92
    MTBE 380.26
    2-butoxyethanol 249.17
    propionic acid 632.95
    o-xylene 89.23
    formic acid 214.29
    diethyl ether 410.53
    m-xylene 86.52
    p-xylene 103.51
    chlorobenzene 210.56
    dimethyl carbonate 121.27
    n-octane 13.07
    formamide 363.0
    cyclopentanone 431.93
    2-pentanone 279.15
    anisole 207.16
    cyclopentyl methyl ether 276.67
    gamma-butyrolactone 543.1
    1-methoxy-2-propanol 579.5
    pyridine 608.15
    3-pentanone 179.72
    furfural 465.34
    n-dodecane 14.6
    diethylene glycol 432.44
    diisopropyl ether 76.55
    tert-amyl alcohol 603.36
    acetylacetone 254.96
    n-hexadecane 15.97
    acetophenone 173.21
    methyl propionate 310.88
    isopentyl acetate 209.89
    trichloroethylene 1098.95
    n-nonanol 130.81
    cyclohexanol 457.32
    benzyl alcohol 209.5
    2-ethylhexanol 184.05
    isooctanol 114.92
    dipropyl ether 201.5
    1,2-dichlorobenzene 181.18
    ethyl lactate 138.39
    propylene carbonate 341.2
    n-methylformamide 389.31
    2-pentanol 389.64
    n-pentane 30.99
    1-propoxy-2-propanol 314.45
    1-methoxy-2-propyl acetate 219.44
    2-(2-methoxypropoxy) propanol 206.47
    mesitylene 58.16
    ε-caprolactone 381.44
    p-cymene 61.29
    epichlorohydrin 696.54
    1,1,1-trichloroethane 513.57
    2-aminoethanol 595.58
    morpholine-4-carbaldehyde 434.88
    sulfolane 525.59
    2,2,4-trimethylpentane 20.81
    2-methyltetrahydrofuran 538.91
    n-hexyl acetate 183.64
    isooctane 17.57
    2-(2-butoxyethoxy)ethanol 311.57
    sec-butyl acetate 133.83
    tert-butyl acetate 176.76
    decalin 27.67
    glycerin 466.04
    diglyme 580.05
    acrylic acid 436.9
    isopropyl myristate 80.52
    n-butyric acid 739.14
    acetyl acetate 235.3
    di(2-ethylhexyl) phthalate 80.19
    ethyl propionate 181.8
    nitromethane 873.09
    1,2-diethoxyethane 272.11
    benzonitrile 260.28
    trioctyl phosphate 64.47
    1-bromopropane 357.13
    gamma-valerolactone 505.09
    n-decanol 99.75
    triethyl phosphate 89.55
    4-methyl-2-pentanol 144.37
    propionitrile 551.91
    vinylene carbonate 341.4
    1,1,2-trichlorotrifluoroethane 498.04
    DMS 144.0
    cumene 60.53
    2-octanol 95.31
    2-hexanone 211.17
    octyl acetate 101.27
    limonene 94.77
    1,2-dimethoxyethane 648.14
    ethyl orthosilicate 89.19
    tributyl phosphate 76.78
    diacetone alcohol 252.12
    N,N-dimethylaniline 128.26
    acrylonitrile 574.44
    aniline 269.93
    1,3-propanediol 718.48
    bromobenzene 211.35
    dibromomethane 777.2
    1,1,2,2-tetrachloroethane 827.5
    2-methyl-cyclohexyl acetate 131.82
    tetrabutyl urea 99.65
    diisobutyl methanol 98.71
    2-phenylethanol 191.92
    styrene 102.91
    dioctyl adipate 124.56
    dimethyl sulfate 170.49
    ethyl butyrate 199.18
    methyl lactate 185.92
    butyl lactate 119.34
    diethyl carbonate 151.65
    propanediol butyl ether 247.8
    triethyl orthoformate 131.81
    p-tert-butyltoluene 59.49
    methyl 4-tert-butylbenzoate 157.72
    morpholine 1212.56
    tert-butylamine 559.49
    n-dodecanol 80.56
    dimethoxymethane 350.04
    ethylene carbonate 309.36
    cyrene 179.32
    2-ethoxyethyl acetate 166.34
    2-ethylhexyl acetate 145.92
    1,2,4-trichlorobenzene 207.88
    4-methylpyridine 387.53
    dibutyl ether 142.41
    2,6-dimethyl-4-heptanol 98.71
    DEF 312.93
    dimethyl isosorbide 268.76
    tetrachloroethylene 497.82
    eugenol 163.01
    triacetin 177.17
    span 80 197.21
    1,4-butanediol 253.38
    1,1-dichloroethane 708.34
    2-methyl-1-pentanol 257.17
    methyl formate 286.58
    2-methyl-1-butanol 416.98
    n-decane 21.48
    butyronitrile 544.42
    3,7-dimethyl-1-octanol 131.09
    1-chlorooctane 83.59
    1-chlorotetradecane 37.51
    n-nonane 20.49
    undecane 17.14
    tert-butylcyclohexane 27.05
    cyclooctane 18.95
    cyclopentanol 440.62
    tetrahydropyran 857.06
    tert-amyl methyl ether 202.03
    2,5,8-trioxanonane 396.11
    1-hexene 117.26
    2-isopropoxyethanol 299.77
    2,2,2-trifluoroethanol 198.47
    methyl butyrate 273.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction