2-Ethoxyethyl isobutyrate

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  • Identifiers

    CAS number
    54396-97-3

    Molecular formula
    C8H16O3

    SMILES
    CCOCCOC(=O)C(C)C

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Fruity 96.65%
    Sweet 63.16%
    Ethereal 58.66%
    Pineapple 52.91%
    Tropical 49.66%
    Apple 48.21%
    Winey 39.28%
    Rummy 38.05%
    Banana 36.5%
    Green 36.4%

     

    Flavor
    Fruity 88.86%
    Sweet 72.96%
    Pineapple 54.95%
    Green 52.12%
    Apple 50.79%
    Tropical 48.65%
    Fruit 42.18%
    Berry 37.88%
    Banana 37.65%
    Bitter 34.54%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    7.3 (neutral)

    Molecular weight
    160.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    178°C

    Flash point

    • 62.12 ˚C est.

  • Synonyms

    • 2-Ethoxyethyl isobutyrate
    • 54396-97-3
    • EINECS 259-146-0
    • Propanoic acid, 2-methyl-, 2-ethoxyethyl ester
    • AI3-21633
    • DTXSID9068952
    • RefChem:471668
    • DTXCID7041700
    • 259-146-0
    • Isobutyric Acid 2-Ethoxyethyl Ester
    • 2-Ethoxyethyl 2-methylpropanoate
    • MFCD00009250
    • ISOBUTYRICACID2-ETHOXYETHYLESTER
    • Cellosolve Isobutyrate
    • Ethylene Glycol Monoethyl Ether Isobutyrate
    • SCHEMBL4676247
    • SCHEMBL4676252
    • SCHEMBL10761885
    • ANSOCBLHUNAGRK-UHFFFAOYSA-
    • 2-Ethoxyethyl 2-methylpropanoate #
    • 2-Ethoxyethyl isobutyrate, >=99%
    • AKOS024342549
    • SY053774
    • DB-052560
    • CS-0453471
    • I0282
    • NS00033072
    • D91115
    • InChI=1/C8H16O3/c1-4-10-5-6-11-8(9)7(2)3/h7H,4-6H2,1-3H3
    • 54396-97-3

  • Applications

    2-Ethoxyethyl isobutyrate is a glycol ester commonly used as a versatile solvent and plasticizer in industrial formulations. In coatings, inks, and adhesives, it acts as a high-boiling, low-odor solvent that improves solvency and film formation. It is also employed as a plasticizer for polymers such as PVC and polyurethanes, enhancing flexibility and processability. In UV- and thermally cured coatings, it can function as a reactive or non-reactive diluent to reduce viscosity and aid processing. It is used in industrial cleaning formulations and degreasers due to its solvating power for resins, oils, and greases. It may serve as an intermediate in chemical synthesis, enabling the preparation of other glycol ester derivatives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2166.4
    methanol 3053.36
    isopropanol 1688.92
    water 18.4
    ethyl acetate 2234.64
    n-propanol 1607.12
    acetone 3115.04
    n-butanol 1495.99
    acetonitrile 3305.26
    DMF 2443.61
    toluene 924.42
    isobutanol 1403.52
    1,4-dioxane 2504.54
    methyl acetate 2058.1
    THF 2344.8
    2-butanone 2093.08
    n-pentanol 1076.59
    sec-butanol 1522.37
    n-hexane 319.91
    ethylene glycol 464.5
    NMP 2410.43
    cyclohexane 508.16
    DMSO 2852.87
    n-butyl acetate 1444.03
    n-octanol 434.02
    chloroform 5465.82
    n-propyl acetate 1294.81
    acetic acid 5138.31
    dichloromethane 4813.66
    cyclohexanone 2690.03
    propylene glycol 488.56
    isopropyl acetate 1262.21
    DMAc 2525.1
    2-ethoxyethanol 1826.87
    isopentanol 1470.59
    n-heptane 120.61
    ethyl formate 1501.09
    1,2-dichloroethane 3007.47
    n-hexanol 795.64
    2-methoxyethanol 2481.39
    isobutyl acetate 779.51
    tetrachloromethane 1356.21
    n-pentyl acetate 781.68
    transcutol 3601.36
    n-heptanol 366.18
    ethylbenzene 575.94
    MIBK 928.71
    2-propoxyethanol 1337.62
    tert-butanol 2432.17
    MTBE 2227.86
    2-butoxyethanol 740.94
    propionic acid 1999.76
    o-xylene 675.29
    formic acid 1992.34
    diethyl ether 1950.98
    m-xylene 599.89
    p-xylene 881.07
    chlorobenzene 1403.48
    dimethyl carbonate 570.8
    n-octane 60.79
    formamide 2411.35
    cyclopentanone 2427.65
    2-pentanone 1574.34
    anisole 1025.74
    cyclopentyl methyl ether 1529.05
    gamma-butyrolactone 2829.39
    1-methoxy-2-propanol 1386.13
    pyridine 2391.86
    3-pentanone 1303.68
    furfural 2596.96
    n-dodecane 43.51
    diethylene glycol 988.04
    diisopropyl ether 532.96
    tert-amyl alcohol 2198.04
    acetylacetone 1805.28
    n-hexadecane 49.78
    acetophenone 1102.85
    methyl propionate 1355.2
    isopentyl acetate 1249.74
    trichloroethylene 5896.23
    n-nonanol 358.4
    cyclohexanol 1731.93
    benzyl alcohol 917.0
    2-ethylhexanol 583.44
    isooctanol 329.69
    dipropyl ether 622.08
    1,2-dichlorobenzene 1377.24
    ethyl lactate 471.72
    propylene carbonate 1588.24
    n-methylformamide 1760.43
    2-pentanol 1066.04
    n-pentane 247.07
    1-propoxy-2-propanol 882.82
    1-methoxy-2-propyl acetate 960.25
    2-(2-methoxypropoxy) propanol 697.13
    mesitylene 373.21
    ε-caprolactone 2469.62
    p-cymene 330.41
    epichlorohydrin 2976.21
    1,1,1-trichloroethane 3604.1
    2-aminoethanol 926.38
    morpholine-4-carbaldehyde 2384.49
    sulfolane 2923.93
    2,2,4-trimethylpentane 178.99
    2-methyltetrahydrofuran 2333.15
    n-hexyl acetate 1027.13
    isooctane 96.13
    2-(2-butoxyethoxy)ethanol 895.8
    sec-butyl acetate 934.6
    tert-butyl acetate 1262.51
    decalin 221.92
    glycerin 694.76
    diglyme 1881.85
    acrylic acid 1834.68
    isopropyl myristate 330.42
    n-butyric acid 2561.72
    acetyl acetate 1707.81
    di(2-ethylhexyl) phthalate 331.06
    ethyl propionate 1082.52
    nitromethane 6067.47
    1,2-diethoxyethane 1317.09
    benzonitrile 1410.95
    trioctyl phosphate 228.88
    1-bromopropane 1779.28
    gamma-valerolactone 2953.12
    n-decanol 240.92
    triethyl phosphate 423.89
    4-methyl-2-pentanol 561.59
    propionitrile 1884.32
    vinylene carbonate 1572.73
    1,1,2-trichlorotrifluoroethane 2718.45
    DMS 850.43
    cumene 391.06
    2-octanol 294.33
    2-hexanone 1085.83
    octyl acetate 403.88
    limonene 540.61
    1,2-dimethoxyethane 2529.34
    ethyl orthosilicate 438.88
    tributyl phosphate 359.3
    diacetone alcohol 1148.91
    N,N-dimethylaniline 713.34
    acrylonitrile 2243.99
    aniline 1159.18
    1,3-propanediol 1422.47
    bromobenzene 1562.55
    dibromomethane 3258.21
    1,1,2,2-tetrachloroethane 4738.27
    2-methyl-cyclohexyl acetate 668.1
    tetrabutyl urea 410.45
    diisobutyl methanol 349.81
    2-phenylethanol 703.95
    styrene 740.99
    dioctyl adipate 527.01
    dimethyl sulfate 933.79
    ethyl butyrate 910.22
    methyl lactate 543.66
    butyl lactate 562.56
    diethyl carbonate 650.14
    propanediol butyl ether 657.87
    triethyl orthoformate 615.01
    p-tert-butyltoluene 300.96
    methyl 4-tert-butylbenzoate 679.84
    morpholine 2967.26
    tert-butylamine 1629.45
    n-dodecanol 174.82
    dimethoxymethane 1263.55
    ethylene carbonate 1345.96
    cyrene 686.48
    2-ethoxyethyl acetate 985.95
    2-ethylhexyl acetate 1006.47
    1,2,4-trichlorobenzene 1578.08
    4-methylpyridine 2484.44
    dibutyl ether 645.07
    2,6-dimethyl-4-heptanol 349.81
    DEF 2058.56
    dimethyl isosorbide 1115.55
    tetrachloroethylene 3776.49
    eugenol 652.74
    triacetin 915.98
    span 80 599.13
    1,4-butanediol 625.55
    1,1-dichloroethane 3370.27
    2-methyl-1-pentanol 1087.84
    methyl formate 1397.1
    2-methyl-1-butanol 1436.4
    n-decane 81.98
    butyronitrile 1920.21
    3,7-dimethyl-1-octanol 478.28
    1-chlorooctane 354.26
    1-chlorotetradecane 119.23
    n-nonane 84.38
    undecane 55.81
    tert-butylcyclohexane 198.42
    cyclooctane 136.72
    cyclopentanol 1452.83
    tetrahydropyran 2510.91
    tert-amyl methyl ether 1623.95
    2,5,8-trioxanonane 1100.69
    1-hexene 862.15
    2-isopropoxyethanol 1136.93
    2,2,2-trifluoroethanol 1639.09
    methyl butyrate 1588.56

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction