2-Ethoxyethanol

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  • Identifiers

    CAS number
    110-80-5

    Molecular formula
    C4H10O2

    SMILES
    CCOCCO

    Safety labels

    Flammable
    Flammable

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

  • Odor profile

    Ethereal 67.38%
    Alcoholic 59.86%
    Sweet 48.14%
    Solvent 44.8%
    Fruity 40.42%
    Fermented 39.25%
    Oily 31.27%
    Winey 26.89%
    Odorless 26.83%
    Musty 26.58%

    Scent© AI

    Odor threshold>

    • Odor Threshold Low: 0.3 [mmHg]. Odor Threshold High: 24.0 [mmHg]. Detection odor threshold from AIHA (mean = 2.7 ppm)
    • ...Odor threshold of about 25 ppm and a strong odor at about 50 ppm.
    • Human volunteers with some work experience in industrial environments reported that /odor/ levels of 125 ppm were noticeable and that the intolerable odor level was higher then 255 ppm. Thus the warning properties should not be relied up on to prevent prolonged daily exposures to a concentration of vapors that could cause adverse affects.

  • Properties

    XLogP3-AA
    -0.3

    Molecular weight
    90.12 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -94 °F (NTP, 1992)
    • -70 °C
    • -94 °F
    • -130 °F

    Boiling point

    • 275 °F at 760 mmHg (NTP, 1992)
    • 135 °C
    • 135.7 °C
    • 135.00 °C. @ 760.00 mm Hg
    • 275 °F

    Flash point est.
    43.51 ˚C

    Flash point expt.

    • 105 °F (NTP, 1992)
    • 43 °C
    • 110 °F (43 °C) (closed cup)
    • 120 °F (49 °C) open cup
    • 202 °F
    • 44 °C c.c.
    • 105 °F
    • 110 °F

    Solubility expt.

    • greater than or equal to 100 mg/mL at 64 °F (NTP, 1992)
    • 1000000 mg/L
    • Miscible with water
    • Very soluble in acetone, ethyl ether, ethanol
    • Miscible with hydrocarbons
    • Miscible in all proportions of acetone, benzene, carbon tetrachloride, ethyl ether, methanol, and water.
    • 1000 mg/mL
    • Solubility in water: miscible
    • Miscible

  • Synonyms

    • 2-Ethoxyethanol
    • 110-80-5
    • Cellosolve
    • ETHYLENE GLYCOL MONOETHYL ETHER
    • Oxitol
    • Ethyl cellosolve
    • Ethanol, 2-ethoxy-
    • Ethyl glycol
    • Emkanol
    • Hydroxy ether
    • Ethylethylene glycol
    • Ethylene glycol ethyl ether
    • Dowanol EE
    • Cellosolve solvent
    • 2-Ethoxyethyl alcohol
    • Glycol monoethyl ether
    • 2-Ethoxyethan-1-Ol
    • Plastiazan 60
    • Ethoxyethanol
    • Solvid
    • EGEE
    • Jeffersol EE
    • beta-Ethoxyethanol
    • Bikanol E 1
    • Solvulose
    • Etoksyetylowy alkohol
    • Ektasolve EE
    • Dowanol 8
    • Celosolv
    • Ethyl ethylene glycol
    • Ethyl icinol
    • EE solvent
    • Glycol ether EE
    • 2-ethoxy-ethanol
    • 2-Ethoxy ethanol
    • HOCH2CH2OC2H5
    • NCI-C54853
    • .beta.-Ethoxyethanol
    • HSDB 54
    • CCRIS 2294
    • 2ethoxyethanol
    • DTXSID7024087
    • Ether monoethylique de l'ethylene-glycol
    • Ethylene glycol monoethyl ether (EGMEE)
    • Cellosolve(R)
    • Athylenglykol-monoathylather
    • UNII-IDK7C2HS09
    • Ethyl-2-hydroxyethyl ether
    • NSC 8837
    • Bikanol E1
    • EINECS 203-804-1
    • UN1171
    • 2-Ethoxyethanol (cellosolve)
    • Eter monoetilico del etilenglicol
    • AI3-01236
    • NSC-8837
    • IDK7C2HS09
    • 2-ETHOXYETHANOL [MI]
    • DTXCID604087
    • CHEBI:46788
    • NSC8837
    • 2-ETHOXYETHANOL [USP-RS]
    • EC 203-804-1
    • ETHYLENE GLYCOL MONOETHYL ETHER [II]
    • ETHYLENE GLYCOL MONOETHYL ETHER [HSDB]
    • Celosolv [Czech]
    • ETX
    • Ethoxyethanol, 2-
    • ethylcellosolve
    • 2-ETHOXYETHANOL (USP-RS)
    • 2EE
    • CAS-110-80-5
    • Etoksyetylowy alkohol [Polish]
    • ETHYLENE GLYCOL MONOETHYL ETHER (II)
    • Athylenglykol-monoathylather [German]
    • RCRA waste no. U359
    • ethylene glycol-monoethyl ether
    • 2-ethoxyetanol
    • betaEthoxyethanol
    • Eter monoetilico del etilenglicol [Spanish]
    • 2-Ehoxyethanol
    • 2-ethyoxyethanol
    • PolySolv EE
    • Ethanol, 2ethoxy
    • ethoxyethyl alcohol
    • Ether monoethylique de l'ethylene-glycol [French]
    • 2Ethoxyethyl alcohol
    • Cellosolve (OSHA)
    • MFCD00002869
    • 1-ethoxy-2-ethanol
    • Monoethyl glycol ether
    • EtOCH2CH2OH
    • ethyl 2-hydroxyethyl ether
    • ethyleneglycol monoethylether
    • ETHOXYETHANOL [INCI]
    • ethylene glycol monoethylether
    • ethyleneglycol monoethyl ether
    • WLN: Q2O2
    • BIDD:ER0296
    • CHEMBL119596
    • Glycol monoethyl ether (OSHA)
    • ethylene glycol mono ethyl ether
    • 2-Ethoxyethanol (ACGIH:OSHA)
    • 2-Ethoxyethanol, ~99% (GC)
    • 2-Ethoxyethanol, LR, >=99%
    • dimethylene glycol monoethyl ether
    • Ethylene glycol monoethyl ether [UN1171] [Flammable liquid]
    • 2-Ethoxyethanol, analytical standard
    • Tox21_201697
    • Tox21_300031
    • STL282734
    • AKOS000119042
    • MONOETHYLENE GLYCOL ETHYL ETHER
    • DB02249
    • 2-Ethoxyethanol, for synthesis, 99.0%
    • 2-Ethoxyethanol, ReagentPlus(R), 99%
    • NCGC00091522-01
    • NCGC00091522-02
    • NCGC00091522-03
    • NCGC00254064-01
    • NCGC00259246-01
    • BP-31042
    • PD008106
    • E0047
    • NS00007272
    • EN300-19199
    • 2-Ethoxyethanol, SAJ first grade, >=97.0%
    • 2-Ethoxyethanol, SAJ special grade, >=99.0%

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 969.79
    methanol 1929.29
    isopropanol 569.86
    water 72.44
    ethyl acetate 189.17
    n-propanol 650.75
    acetone 381.51
    n-butanol 455.25
    acetonitrile 476.77
    DMF 853.96
    toluene 39.98
    isobutanol 343.93
    1,4-dioxane 524.14
    methyl acetate 253.1
    THF 534.14
    2-butanone 217.54
    n-pentanol 217.14
    sec-butanol 387.86
    n-hexane 22.73
    ethylene glycol 718.24
    NMP 507.62
    cyclohexane 44.57
    DMSO 1195.67
    n-butyl acetate 111.83
    n-octanol 87.69
    chloroform 433.32
    n-propyl acetate 88.58
    acetic acid 1279.87
    dichloromethane 467.23
    cyclohexanone 301.42
    propylene glycol 523.25
    isopropyl acetate 75.96
    DMAc 405.88
    2-ethoxyethanol 397.71
    isopentanol 223.48
    n-heptane 30.29
    ethyl formate 216.12
    1,2-dichloroethane 261.75
    n-hexanol 199.1
    2-methoxyethanol 974.77
    isobutyl acetate 46.04
    tetrachloromethane 106.54
    n-pentyl acetate 66.1
    transcutol 575.01
    n-heptanol 80.47
    ethylbenzene 21.61
    MIBK 57.51
    2-propoxyethanol 373.96
    tert-butanol 438.77
    MTBE 159.15
    2-butoxyethanol 165.52
    propionic acid 563.21
    o-xylene 36.32
    formic acid 869.44
    diethyl ether 197.51
    m-xylene 30.16
    p-xylene 30.45
    chlorobenzene 97.28
    dimethyl carbonate 56.06
    n-octane 9.3
    formamide 647.63
    cyclopentanone 357.53
    2-pentanone 144.95
    anisole 74.2
    cyclopentyl methyl ether 164.25
    gamma-butyrolactone 443.45
    1-methoxy-2-propanol 445.17
    pyridine 305.38
    3-pentanone 100.36
    furfural 445.58
    n-dodecane 7.92
    diethylene glycol 497.5
    diisopropyl ether 30.16
    tert-amyl alcohol 292.87
    acetylacetone 139.13
    n-hexadecane 8.47
    acetophenone 75.66
    methyl propionate 153.16
    isopentyl acetate 79.85
    trichloroethylene 387.31
    n-nonanol 72.47
    cyclohexanol 285.46
    benzyl alcohol 120.99
    2-ethylhexanol 93.26
    isooctanol 57.77
    dipropyl ether 97.62
    1,2-dichlorobenzene 86.49
    ethyl lactate 85.5
    propylene carbonate 184.94
    n-methylformamide 633.77
    2-pentanol 191.37
    n-pentane 33.39
    1-propoxy-2-propanol 225.59
    1-methoxy-2-propyl acetate 105.33
    2-(2-methoxypropoxy) propanol 142.05
    mesitylene 21.1
    ε-caprolactone 243.14
    p-cymene 28.79
    epichlorohydrin 366.18
    1,1,1-trichloroethane 174.12
    2-aminoethanol 808.66
    morpholine-4-carbaldehyde 530.43
    sulfolane 520.61
    2,2,4-trimethylpentane 14.1
    2-methyltetrahydrofuran 325.19
    n-hexyl acetate 94.79
    isooctane 8.01
    2-(2-butoxyethoxy)ethanol 198.33
    sec-butyl acetate 44.5
    tert-butyl acetate 66.39
    decalin 13.44
    glycerin 678.94
    diglyme 345.48
    acrylic acid 540.14
    isopropyl myristate 37.33
    n-butyric acid 459.67
    acetyl acetate 115.66
    di(2-ethylhexyl) phthalate 52.68
    ethyl propionate 72.27
    nitromethane 900.87
    1,2-diethoxyethane 139.05
    benzonitrile 146.16
    trioctyl phosphate 40.63
    1-bromopropane 151.32
    gamma-valerolactone 487.01
    n-decanol 52.21
    triethyl phosphate 50.76
    4-methyl-2-pentanol 66.72
    propionitrile 281.67
    vinylene carbonate 192.55
    1,1,2-trichlorotrifluoroethane 474.1
    DMS 76.79
    cumene 19.94
    2-octanol 51.07
    2-hexanone 86.42
    octyl acetate 54.07
    limonene 51.04
    1,2-dimethoxyethane 424.72
    ethyl orthosilicate 47.09
    tributyl phosphate 48.59
    diacetone alcohol 132.87
    N,N-dimethylaniline 58.44
    acrylonitrile 385.13
    aniline 147.75
    1,3-propanediol 722.29
    bromobenzene 71.83
    dibromomethane 291.45
    1,1,2,2-tetrachloroethane 312.36
    2-methyl-cyclohexyl acetate 60.84
    tetrabutyl urea 70.76
    diisobutyl methanol 48.43
    2-phenylethanol 101.07
    styrene 33.43
    dioctyl adipate 69.03
    dimethyl sulfate 115.1
    ethyl butyrate 83.15
    methyl lactate 156.15
    butyl lactate 82.55
    diethyl carbonate 58.08
    propanediol butyl ether 173.62
    triethyl orthoformate 66.71
    p-tert-butyltoluene 28.95
    methyl 4-tert-butylbenzoate 78.89
    morpholine 641.8
    tert-butylamine 251.28
    n-dodecanol 40.91
    dimethoxymethane 269.58
    ethylene carbonate 153.07
    cyrene 134.0
    2-ethoxyethyl acetate 89.31
    2-ethylhexyl acetate 61.65
    1,2,4-trichlorobenzene 100.37
    4-methylpyridine 215.62
    dibutyl ether 69.88
    2,6-dimethyl-4-heptanol 48.43
    DEF 238.7
    dimethyl isosorbide 183.54
    tetrachloroethylene 268.51
    eugenol 104.78
    triacetin 102.54
    span 80 150.54
    1,4-butanediol 279.35
    1,1-dichloroethane 225.7
    2-methyl-1-pentanol 134.2
    methyl formate 354.75
    2-methyl-1-butanol 238.33
    n-decane 12.95
    butyronitrile 262.85
    3,7-dimethyl-1-octanol 73.14
    1-chlorooctane 42.23
    1-chlorotetradecane 17.52
    n-nonane 13.29
    undecane 9.52
    tert-butylcyclohexane 13.17
    cyclooctane 12.0
    cyclopentanol 383.54
    tetrahydropyran 372.45
    tert-amyl methyl ether 105.48
    2,5,8-trioxanonane 259.18
    1-hexene 63.47
    2-isopropoxyethanol 191.19
    2,2,2-trifluoroethanol 358.34
    methyl butyrate 116.71

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction