2-Ethoxyethanethiol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    17362-04-8

    Molecular formula
    C4H10OS

    SMILES
    CCOCCS

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sulfurous 76.59%
    Meaty 70.83%
    Onion 53.52%
    Savory 46.05%
    Alliaceous 42.08%
    Garlic 41.04%
    Vegetable 39.62%
    Roasted 39.09%
    Cooked 33.35%
    Sweet 30.57%

     

    Flavor
    Sulfurous 56.6%
    Sweet 52.24%
    Vegetable 43.59%
    Onion 40.93%
    Alcoholic 34.69%
    Meaty 32.3%
    Sulfury 30.65%
    Coffee 30.36%
    Potato 29.84%
    Roasted 28.75%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.7

    pKa est.
    7.88 (neutral)

    Molecular weight
    106.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    129°C

    Flash point

    • 19.94 ˚C est.

  • Synonyms

    • 2-Ethoxyethanethiol
    • 2-ethoxyethane-1-thiol
    • 17362-04-8
    • Ethanethiol, 2-ethoxy-
    • TT795DE88E
    • EINECS 241-390-4
    • DTXSID30169639
    • RefChem:86839
    • DTXCID8092130
    • 241-390-4
    • 2-mercaptoethyl ethyl ether
    • 2-Thioather
    • UNII-TT795DE88E
    • SCHEMBL193452
    • SCHEMBL193453
    • SCHEMBL547441
    • SCHEMBL5248014
    • NS00025702
    • EN300-95872
    • 17362-04-8

  • Applications

    2-Ethoxyethanethiol is an organosulfur compound with a thiol group and an ethoxy moiety. In industrial practice, it is primarily used as an intermediate to synthesize thioether derivatives and to introduce sulfur-containing functionality in organic synthesis. It serves as a curing agent for epoxy resins, enabling thiol-epoxy crosslinking in coatings and adhesives. It can act as a chain-transfer agent in radical polymerizations to control molecular weight. It can function as a surface-binding linker for metal substrates (e.g., gold) in electronics and sensing applications. It is used as a reagent to introduce sulfur-containing functionality in organic synthesis. Use is subject to local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 541.76
    methanol 814.86
    isopropanol 349.83
    water 12.92
    ethyl acetate 198.1
    n-propanol 391.88
    acetone 458.48
    n-butanol 332.41
    acetonitrile 402.96
    DMF 523.92
    toluene 110.77
    isobutanol 255.98
    1,4-dioxane 515.51
    methyl acetate 273.94
    THF 604.12
    2-butanone 304.46
    n-pentanol 237.69
    sec-butanol 322.75
    n-hexane 72.13
    ethylene glycol 302.49
    NMP 441.77
    cyclohexane 106.37
    DMSO 707.31
    n-butyl acetate 175.88
    n-octanol 145.12
    chloroform 733.95
    n-propyl acetate 135.46
    acetic acid 683.21
    dichloromethane 618.07
    cyclohexanone 398.39
    propylene glycol 279.18
    isopropyl acetate 110.15
    DMAc 400.53
    2-ethoxyethanol 403.24
    isopentanol 216.94
    n-heptane 74.59
    ethyl formate 167.41
    1,2-dichloroethane 325.18
    n-hexanol 264.37
    2-methoxyethanol 641.38
    isobutyl acetate 98.6
    tetrachloromethane 196.7
    n-pentyl acetate 121.93
    transcutol 774.02
    n-heptanol 126.61
    ethylbenzene 61.76
    MIBK 113.05
    2-propoxyethanol 416.4
    tert-butanol 356.54
    MTBE 230.55
    2-butoxyethanol 218.45
    propionic acid 348.88
    o-xylene 81.46
    formic acid 287.35
    diethyl ether 272.25
    m-xylene 74.2
    p-xylene 86.38
    chlorobenzene 174.4
    dimethyl carbonate 63.43
    n-octane 25.61
    formamide 241.28
    cyclopentanone 444.79
    2-pentanone 204.94
    anisole 142.31
    cyclopentyl methyl ether 237.77
    gamma-butyrolactone 400.54
    1-methoxy-2-propanol 366.43
    pyridine 355.77
    3-pentanone 172.45
    furfural 438.19
    n-dodecane 21.56
    diethylene glycol 444.12
    diisopropyl ether 64.03
    tert-amyl alcohol 279.55
    acetylacetone 219.58
    n-hexadecane 23.57
    acetophenone 137.47
    methyl propionate 154.35
    isopentyl acetate 130.31
    trichloroethylene 552.32
    n-nonanol 121.82
    cyclohexanol 296.62
    benzyl alcohol 162.7
    2-ethylhexanol 148.78
    isooctanol 98.15
    dipropyl ether 169.41
    1,2-dichlorobenzene 149.73
    ethyl lactate 100.39
    propylene carbonate 185.65
    n-methylformamide 302.51
    2-pentanol 198.0
    n-pentane 76.77
    1-propoxy-2-propanol 278.02
    1-methoxy-2-propyl acetate 148.14
    2-(2-methoxypropoxy) propanol 206.14
    mesitylene 49.3
    ε-caprolactone 280.01
    p-cymene 63.04
    epichlorohydrin 409.47
    1,1,1-trichloroethane 340.9
    2-aminoethanol 389.52
    morpholine-4-carbaldehyde 480.76
    sulfolane 450.94
    2,2,4-trimethylpentane 34.05
    2-methyltetrahydrofuran 419.52
    n-hexyl acetate 179.22
    isooctane 20.61
    2-(2-butoxyethoxy)ethanol 271.35
    sec-butyl acetate 89.96
    tert-butyl acetate 113.58
    decalin 36.59
    glycerin 382.81
    diglyme 469.14
    acrylic acid 335.06
    isopropyl myristate 76.42
    n-butyric acid 327.4
    acetyl acetate 151.37
    di(2-ethylhexyl) phthalate 84.14
    ethyl propionate 107.83
    nitromethane 608.53
    1,2-diethoxyethane 241.11
    benzonitrile 205.39
    trioctyl phosphate 65.04
    1-bromopropane 244.21
    gamma-valerolactone 457.97
    n-decanol 88.58
    triethyl phosphate 74.65
    4-methyl-2-pentanol 91.02
    propionitrile 258.3
    vinylene carbonate 180.49
    1,1,2-trichlorotrifluoroethane 412.97
    DMS 120.35
    cumene 54.13
    2-octanol 94.16
    2-hexanone 176.93
    octyl acetate 101.35
    limonene 105.55
    1,2-dimethoxyethane 483.98
    ethyl orthosilicate 75.96
    tributyl phosphate 74.09
    diacetone alcohol 174.25
    N,N-dimethylaniline 110.17
    acrylonitrile 308.97
    aniline 186.91
    1,3-propanediol 387.78
    bromobenzene 161.8
    dibromomethane 447.81
    1,1,2,2-tetrachloroethane 470.59
    2-methyl-cyclohexyl acetate 117.35
    tetrabutyl urea 101.59
    diisobutyl methanol 82.67
    2-phenylethanol 149.03
    styrene 86.11
    dioctyl adipate 113.71
    dimethyl sulfate 119.25
    ethyl butyrate 124.35
    methyl lactate 130.2
    butyl lactate 111.76
    diethyl carbonate 82.25
    propanediol butyl ether 224.67
    triethyl orthoformate 100.14
    p-tert-butyltoluene 61.44
    methyl 4-tert-butylbenzoate 133.67
    morpholine 536.53
    tert-butylamine 230.73
    n-dodecanol 71.56
    dimethoxymethane 252.69
    ethylene carbonate 138.82
    cyrene 181.86
    2-ethoxyethyl acetate 155.46
    2-ethylhexyl acetate 112.18
    1,2,4-trichlorobenzene 198.96
    4-methylpyridine 292.34
    dibutyl ether 146.63
    2,6-dimethyl-4-heptanol 82.67
    DEF 244.76
    dimethyl isosorbide 245.83
    tetrachloroethylene 364.18
    eugenol 150.87
    triacetin 180.61
    span 80 200.34
    1,4-butanediol 206.86
    1,1-dichloroethane 361.81
    2-methyl-1-pentanol 183.77
    methyl formate 197.23
    2-methyl-1-butanol 237.44
    n-decane 34.69
    butyronitrile 236.79
    3,7-dimethyl-1-octanol 124.03
    1-chlorooctane 94.99
    1-chlorotetradecane 42.5
    n-nonane 36.91
    undecane 26.0
    tert-butylcyclohexane 38.0
    cyclooctane 31.71
    cyclopentanol 330.96
    tetrahydropyran 434.8
    tert-amyl methyl ether 170.84
    2,5,8-trioxanonane 343.49
    1-hexene 158.25
    2-isopropoxyethanol 259.21
    2,2,2-trifluoroethanol 193.84
    methyl butyrate 148.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction