2-Dodecen-4-one

Overview IFRA Request a quote

  • Identifiers

    CAS number
    65570-26-5

    Molecular formula
    C12H22O

    SMILES
    CCCCCCCCC(=O)/C=C/C

    Safety labels

  • Odor profile

    Fragrance
    Fruity 79.01%
    Earthy 55.8%
    Mushroom 54.65%
    Herbal 50.27%
    Fatty 49.68%
    Waxy 48.01%
    Green 44.04%
    Sweet 43.98%
    Floral 40.25%
    Fresh 40.22%

     

    Flavor
    Herbal 57.13%
    Fruity 52.31%
    Mushroom 34.14%
    Spicy 34.07%
    Fatty 31.27%
    Sweet 30.86%
    Fresh 30.55%
    Floral 30.46%
    Waxy 29.71%
    Earthy 28.0%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    4.6

    pKa est.
    8.42 (weak base)

    Molecular weight
    182.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    248°C

    Flash point

    • 97.64 ˚C est.

  • Synonyms

    • 2-Dodecen-4-one
    • 65570-26-5
    • dodec-2-en-4-one
    • (E)-dodec-2-en-4-one
    • RBDKOLXWSXOZLC-ONNFQVAWSA-N
    • 65570-26-5

  • Applications

    2-Dodecen-4-one (CAS 65570-26-5) is primarily utilized in fragrance chemistry as an odorant and fragrance ingredient for perfumery, and it is commonly evaluated for use in cosmetics and personal care products as a scent component. In household and cleaning product formulations, it can contribute characteristic aroma notes as a fragrance additive. It also serves as a chemical building block or intermediate in industrial synthesis of aroma compounds, enabling development of more complex fragrance ingredients. In addition, it may be employed as a synthetic intermediate in other specialty chemical routes within industrial manufacturing, subject to formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7321.3
    methanol 6323.48
    isopropanol 8292.72
    water 0.05
    ethyl acetate 8034.48
    n-propanol 7032.81
    acetone 13298.3
    n-butanol 6730.37
    acetonitrile 6670.97
    DMF 5914.35
    toluene 3148.66
    isobutanol 5855.07
    1,4-dioxane 7109.56
    methyl acetate 5017.32
    THF 10807.29
    2-butanone 8869.48
    n-pentanol 4492.99
    sec-butanol 7301.78
    n-hexane 5513.24
    ethylene glycol 306.38
    NMP 3945.65
    cyclohexane 5297.48
    DMSO 6143.03
    n-butyl acetate 7464.1
    n-octanol 1800.38
    chloroform 10819.06
    n-propyl acetate 5371.9
    acetic acid 2688.64
    dichloromethane 10477.96
    cyclohexanone 10986.45
    propylene glycol 776.67
    isopropyl acetate 4797.15
    DMAc 2957.17
    2-ethoxyethanol 2868.65
    isopentanol 5990.31
    n-heptane 1770.04
    ethyl formate 2940.95
    1,2-dichloroethane 8210.46
    n-hexanol 5179.72
    2-methoxyethanol 4664.54
    isobutyl acetate 2673.07
    tetrachloromethane 2252.22
    n-pentyl acetate 3321.05
    transcutol 9513.51
    n-heptanol 1630.92
    ethylbenzene 1774.4
    MIBK 3947.22
    2-propoxyethanol 4653.12
    tert-butanol 8379.57
    MTBE 9759.47
    2-butoxyethanol 2142.54
    propionic acid 2938.56
    o-xylene 1475.1
    formic acid 336.95
    diethyl ether 12716.91
    m-xylene 1767.55
    p-xylene 2030.77
    chlorobenzene 3544.5
    dimethyl carbonate 772.17
    n-octane 531.7
    formamide 644.32
    cyclopentanone 7829.27
    2-pentanone 9002.39
    anisole 2216.83
    cyclopentyl methyl ether 7456.87
    gamma-butyrolactone 6111.03
    1-methoxy-2-propanol 4137.57
    pyridine 6784.49
    3-pentanone 4986.91
    furfural 3546.67
    n-dodecane 223.12
    diethylene glycol 1589.07
    diisopropyl ether 3248.47
    tert-amyl alcohol 6277.78
    acetylacetone 4484.39
    n-hexadecane 271.68
    acetophenone 1757.73
    methyl propionate 4137.6
    isopentyl acetate 5508.08
    trichloroethylene 10588.09
    n-nonanol 1433.85
    cyclohexanol 6777.19
    benzyl alcohol 1612.64
    2-ethylhexanol 3381.81
    isooctanol 1425.93
    dipropyl ether 5964.11
    1,2-dichlorobenzene 2626.34
    ethyl lactate 981.12
    propylene carbonate 3124.44
    n-methylformamide 2560.05
    2-pentanol 5896.32
    n-pentane 2929.5
    1-propoxy-2-propanol 4226.2
    1-methoxy-2-propyl acetate 3440.92
    2-(2-methoxypropoxy) propanol 1547.33
    mesitylene 1175.86
    ε-caprolactone 6704.62
    p-cymene 949.26
    epichlorohydrin 7045.49
    1,1,1-trichloroethane 7889.59
    2-aminoethanol 1199.45
    morpholine-4-carbaldehyde 3563.68
    sulfolane 5738.44
    2,2,4-trimethylpentane 673.16
    2-methyltetrahydrofuran 11514.12
    n-hexyl acetate 3957.27
    isooctane 612.73
    2-(2-butoxyethoxy)ethanol 2396.65
    sec-butyl acetate 3221.53
    tert-butyl acetate 4239.02
    decalin 1177.59
    glycerin 716.98
    diglyme 4320.6
    acrylic acid 1558.84
    isopropyl myristate 1202.95
    n-butyric acid 6521.31
    acetyl acetate 2475.13
    di(2-ethylhexyl) phthalate 742.38
    ethyl propionate 3886.14
    nitromethane 4125.68
    1,2-diethoxyethane 6130.56
    benzonitrile 2950.41
    trioctyl phosphate 633.0
    1-bromopropane 8822.9
    gamma-valerolactone 7205.67
    n-decanol 961.8
    triethyl phosphate 902.55
    4-methyl-2-pentanol 2377.07
    propionitrile 5987.82
    vinylene carbonate 2428.58
    1,1,2-trichlorotrifluoroethane 3350.68
    DMS 1612.7
    cumene 970.16
    2-octanol 1435.6
    2-hexanone 5980.29
    octyl acetate 1386.0
    limonene 2116.65
    1,2-dimethoxyethane 6503.98
    ethyl orthosilicate 996.16
    tributyl phosphate 882.6
    diacetone alcohol 3064.63
    N,N-dimethylaniline 1305.29
    acrylonitrile 4557.2
    aniline 3064.77
    1,3-propanediol 2217.24
    bromobenzene 4048.83
    dibromomethane 9053.2
    1,1,2,2-tetrachloroethane 8636.63
    2-methyl-cyclohexyl acetate 1954.36
    tetrabutyl urea 1098.5
    diisobutyl methanol 1638.75
    2-phenylethanol 1837.37
    styrene 2478.4
    dioctyl adipate 1389.94
    dimethyl sulfate 1047.07
    ethyl butyrate 3895.19
    methyl lactate 991.3
    butyl lactate 1711.19
    diethyl carbonate 1688.29
    propanediol butyl ether 1669.0
    triethyl orthoformate 2025.34
    p-tert-butyltoluene 895.51
    methyl 4-tert-butylbenzoate 1245.85
    morpholine 10064.13
    tert-butylamine 6530.05
    n-dodecanol 705.73
    dimethoxymethane 3890.84
    ethylene carbonate 2455.58
    cyrene 1006.49
    2-ethoxyethyl acetate 2946.13
    2-ethylhexyl acetate 4173.12
    1,2,4-trichlorobenzene 2699.26
    4-methylpyridine 7107.73
    dibutyl ether 4984.63
    2,6-dimethyl-4-heptanol 1638.75
    DEF 6506.11
    dimethyl isosorbide 2351.63
    tetrachloroethylene 5611.16
    eugenol 1170.48
    triacetin 1897.8
    span 80 1645.17
    1,4-butanediol 822.47
    1,1-dichloroethane 10147.02
    2-methyl-1-pentanol 3759.01
    methyl formate 1482.75
    2-methyl-1-butanol 5424.42
    n-decane 508.47
    butyronitrile 8140.17
    3,7-dimethyl-1-octanol 1877.41
    1-chlorooctane 1813.87
    1-chlorotetradecane 542.06
    n-nonane 648.06
    undecane 316.5
    tert-butylcyclohexane 1039.33
    cyclooctane 1191.58
    cyclopentanol 5419.11
    tetrahydropyran 15480.1
    tert-amyl methyl ether 5511.56
    2,5,8-trioxanonane 2367.22
    1-hexene 10825.16
    2-isopropoxyethanol 2453.98
    2,2,2-trifluoroethanol 513.46
    methyl butyrate 5573.93

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction