2-Chlorobenzylamine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    89-97-4

    Molecular formula
    C7H8ClN

    SMILES
    C1=CC=C(C(=C1)CN)Cl

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 49.05%
    Cheesy 40.35%
    Animal 36.09%
    Ripe 34.17%
    Meaty 29.84%
    Phenolic 28.85%
    Burnt 26.44%
    Smoky 26.13%
    Odorless 25.89%
    Sweet 24.29%

     

    Flavor
    Meaty 45.51%
    Sulfurous 39.42%
    Mild 31.71%
    Fishy 30.53%
    Phenolic 27.55%
    Onion 27.39%
    Sulfury 26.7%
    Roasted 26.63%
    Egg 24.28%
    Garlic 24.12%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    4.41 (weak acid)

    Molecular weight
    141.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    218°C

    Flash point

    • 98.08 ˚C est.

  • Synonyms

    • 2-Chlorobenzylamine
    • 89-97-4
    • (2-Chlorophenyl)methanamine
    • o-Chlorobenzylamine
    • Benzenemethanamine, 2-chloro-
    • Benzylamine, o-chloro-
    • o-Chlorobenzyl amine
    • 2-Chlorobenzenemethanamine
    • 2-Chloro-benzylamine
    • (2-chlorophenyl)methylamine
    • 2-chlorobenzyl amine
    • MFCD00008108
    • UNII-L790J4Y7A3
    • 1-(2-chlorophenyl)methanamine
    • L790J4Y7A3
    • EINECS 201-955-8
    • NSC 60118
    • NSC-60118
    • CHEMBL12712
    • DTXSID3059002
    • EC 201-955-8
    • TICLOPIDINE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
    • TICLOPIDINE HYDROCHLORIDE IMPURITY C (EP IMPURITY)
    • NSC60118
    • 2-Choro-benzylamine
    • 2-chloro benzylamine
    • o-chloro-benzyl amine
    • ortho-chlorobenzylamine
    • 2-chloro benzyl amine
    • 2-Chlorobenzylamine, 95%
    • SCHEMBL9299
    • (2-chlorophenyl)-methyl-amine
    • Benzylamine, o-chloro-(8CI)
    • (2-Chlorophenyl)methanamine #
    • [(2-Chlorophenyl)methyl]amine
    • DTXCID6048672
    • BDBM50029104
    • CK2391
    • AKOS000119563
    • CS-W016433
    • PS-5316
    • DB-020922
    • NS00007676
    • EN300-16218
    • 1-Aminomethyl-2-chlorobenzene2-Chlorobenzylamine
    • Q27282805
    • Z55002587
    • F2190-0389
    • 2-Chlorobenzenemethanamine ; 1-Aminomethyl-2-chlorobenzene
    • 201-955-8

  • Applications

    2-Chlorobenzylamine (CAS 89-97-4) is primarily used as an organic synthesis intermediate. It serves as a building block for the preparation of heterocyclic compounds such as benzimidazoles and other arylamine derivatives used in medicinal chemistry and agricultural chemical research, and it functions as a precursor to dye and pigment intermediates as well as to amine linkers in polymers and coatings. It is also evaluated as a source of benzylamine functionality for fragrance and cosmetic chemistries, depending on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 297.68
    methanol 356.24
    isopropanol 196.91
    water 9.71
    ethyl acetate 286.95
    n-propanol 234.05
    acetone 613.56
    n-butanol 184.73
    acetonitrile 345.75
    DMF 839.29
    toluene 130.27
    isobutanol 145.8
    1,4-dioxane 906.04
    methyl acetate 294.12
    THF 1098.73
    2-butanone 370.68
    n-pentanol 129.79
    sec-butanol 128.14
    n-hexane 6.32
    ethylene glycol 85.11
    NMP 700.0
    cyclohexane 9.68
    DMSO 1231.55
    n-butyl acetate 214.33
    n-octanol 62.48
    chloroform 590.41
    n-propyl acetate 183.43
    acetic acid 379.24
    dichloromethane 470.02
    cyclohexanone 571.88
    propylene glycol 59.44
    isopropyl acetate 146.75
    DMAc 363.82
    2-ethoxyethanol 230.01
    isopentanol 129.3
    n-heptane 14.38
    ethyl formate 297.7
    1,2-dichloroethane 344.22
    n-hexanol 140.88
    2-methoxyethanol 401.69
    isobutyl acetate 114.13
    tetrachloromethane 134.5
    n-pentyl acetate 119.23
    transcutol 396.84
    n-heptanol 82.31
    ethylbenzene 40.11
    MIBK 165.85
    2-propoxyethanol 272.19
    tert-butanol 221.76
    MTBE 183.7
    2-butoxyethanol 158.76
    propionic acid 228.28
    o-xylene 59.56
    formic acid 209.41
    diethyl ether 207.12
    m-xylene 79.01
    p-xylene 53.32
    chlorobenzene 197.06
    dimethyl carbonate 138.87
    n-octane 6.49
    formamide 332.18
    cyclopentanone 847.42
    2-pentanone 301.07
    anisole 137.36
    cyclopentyl methyl ether 302.84
    gamma-butyrolactone 886.58
    1-methoxy-2-propanol 241.03
    pyridine 472.67
    3-pentanone 184.37
    furfural 598.97
    n-dodecane 4.92
    diethylene glycol 234.25
    diisopropyl ether 50.14
    tert-amyl alcohol 128.11
    acetylacetone 344.04
    n-hexadecane 5.62
    acetophenone 133.18
    methyl propionate 222.57
    isopentyl acetate 150.87
    trichloroethylene 717.82
    n-nonanol 55.13
    cyclohexanol 138.51
    benzyl alcohol 118.83
    2-ethylhexanol 79.04
    isooctanol 67.54
    dipropyl ether 108.99
    1,2-dichlorobenzene 148.54
    ethyl lactate 84.05
    propylene carbonate 351.56
    n-methylformamide 476.69
    2-pentanol 94.83
    n-pentane 7.81
    1-propoxy-2-propanol 177.61
    1-methoxy-2-propyl acetate 181.84
    2-(2-methoxypropoxy) propanol 106.51
    mesitylene 46.69
    ε-caprolactone 402.22
    p-cymene 37.73
    epichlorohydrin 768.47
    1,1,1-trichloroethane 356.13
    2-aminoethanol 137.89
    morpholine-4-carbaldehyde 556.66
    sulfolane 896.17
    2,2,4-trimethylpentane 8.24
    2-methyltetrahydrofuran 551.86
    n-hexyl acetate 118.8
    isooctane 8.36
    2-(2-butoxyethoxy)ethanol 161.0
    sec-butyl acetate 90.04
    tert-butyl acetate 165.82
    decalin 8.53
    glycerin 134.38
    diglyme 321.83
    acrylic acid 204.53
    isopropyl myristate 47.93
    n-butyric acid 310.08
    acetyl acetate 164.03
    di(2-ethylhexyl) phthalate 54.37
    ethyl propionate 122.49
    nitromethane 846.76
    1,2-diethoxyethane 171.47
    benzonitrile 187.61
    trioctyl phosphate 46.2
    1-bromopropane 151.39
    gamma-valerolactone 951.35
    n-decanol 41.36
    triethyl phosphate 63.22
    4-methyl-2-pentanol 60.01
    propionitrile 220.54
    vinylene carbonate 352.75
    1,1,2-trichlorotrifluoroethane 397.96
    DMS 106.58
    cumene 31.15
    2-octanol 52.26
    2-hexanone 189.8
    octyl acetate 64.17
    limonene 56.12
    1,2-dimethoxyethane 400.93
    ethyl orthosilicate 61.53
    tributyl phosphate 51.28
    diacetone alcohol 192.52
    N,N-dimethylaniline 86.08
    acrylonitrile 285.36
    aniline 177.52
    1,3-propanediol 214.22
    bromobenzene 179.44
    dibromomethane 296.0
    1,1,2,2-tetrachloroethane 446.67
    2-methyl-cyclohexyl acetate 91.19
    tetrabutyl urea 68.55
    diisobutyl methanol 51.59
    2-phenylethanol 121.79
    styrene 57.83
    dioctyl adipate 65.61
    dimethyl sulfate 265.37
    ethyl butyrate 132.93
    methyl lactate 119.72
    butyl lactate 92.35
    diethyl carbonate 82.89
    propanediol butyl ether 110.35
    triethyl orthoformate 88.02
    p-tert-butyltoluene 39.71
    methyl 4-tert-butylbenzoate 119.1
    morpholine 724.34
    tert-butylamine 104.19
    n-dodecanol 31.88
    dimethoxymethane 430.76
    ethylene carbonate 289.51
    cyrene 143.92
    2-ethoxyethyl acetate 157.78
    2-ethylhexyl acetate 113.32
    1,2,4-trichlorobenzene 180.72
    4-methylpyridine 401.38
    dibutyl ether 64.67
    2,6-dimethyl-4-heptanol 51.59
    DEF 268.49
    dimethyl isosorbide 218.66
    tetrachloroethylene 330.02
    eugenol 119.63
    triacetin 110.47
    span 80 102.48
    1,4-butanediol 91.86
    1,1-dichloroethane 349.83
    2-methyl-1-pentanol 89.67
    methyl formate 411.88
    2-methyl-1-butanol 115.82
    n-decane 8.18
    butyronitrile 234.51
    3,7-dimethyl-1-octanol 54.01
    1-chlorooctane 41.31
    1-chlorotetradecane 16.17
    n-nonane 7.78
    undecane 6.06
    tert-butylcyclohexane 11.03
    cyclooctane 4.92
    cyclopentanol 212.52
    tetrahydropyran 534.15
    tert-amyl methyl ether 100.38
    2,5,8-trioxanonane 207.88
    1-hexene 34.96
    2-isopropoxyethanol 145.64
    2,2,2-trifluoroethanol 201.47
    methyl butyrate 186.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction