2-Butylpyrazine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    29460-91-1

    Molecular formula
    C8H12N2

    SMILES
    CCCCC1=NC=CN=C1

    Safety labels

  • Odor profile

    Fragrance
    Green 75.18%
    Nutty 65.31%
    Earthy 57.15%
    Roasted 56.67%
    Vegetable 48.96%
    Musty 45.08%
    Cocoa 37.19%
    Hazelnut 36.7%
    Meaty 33.5%
    Potato 33.5%

     

    Flavor
    Green 85.79%
    Nutty 63.75%
    Fatty 52.9%
    Earthy 51.05%
    Vegetable 49.88%
    Pepper 47.6%
    Herbal 43.24%
    Musty 40.42%
    Roasted 40.21%
    Raw 39.95%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.6

    pKa est.
    4.03 (weak acid)

    Molecular weight
    136.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    217°C

    Flash point

    • 90.92 ˚C est.

  • Synonyms

    • 2-butylpyrazine
    • 29460-91-1
    • butylpyrazine
    • Pyrazine,2-butyl-
    • butyl pyrazine
    • Pyrazine, butyl
    • CHEMBL93499
    • SCHEMBL293167
    • SCHEMBL499883
    • SCHEMBL559050
    • SCHEMBL4412197
    • SCHEMBL4925057
    • SCHEMBL4927993
    • SCHEMBL11515740
    • DTXSID70335932
    • TVAVRPSANVGCNH-UHFFFAOYSA-N
    • AKOS006291470
    • DB-086665
    • 29460-91-1

  • Applications

    2-Butylpyrazine (CAS 29460-91-1) is a heterocyclic aroma compound whose odor activity makes it useful as an odorant and fragrance ingredient in perfumery and cosmetics, contributing to savory, roasted, and nutty notes. In the flavor industry, it may be used to enhance savory profiles in processed foods and flavor formulations. In household products, it can be added to air fresheners and cleaners to establish a consistent odor. It may also serve as a synthetic intermediate in the industrial synthesis of other pyrazine-based compounds, subject to applicable regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 408.62
    methanol 501.27
    isopropanol 219.66
    water 0.78
    ethyl acetate 300.64
    n-propanol 316.19
    acetone 425.07
    n-butanol 298.11
    acetonitrile 245.53
    DMF 846.11
    toluene 180.19
    isobutanol 233.81
    1,4-dioxane 383.19
    methyl acetate 240.02
    THF 501.19
    2-butanone 267.74
    n-pentanol 184.77
    sec-butanol 180.24
    n-hexane 20.05
    ethylene glycol 133.86
    NMP 596.37
    cyclohexane 58.1
    DMSO 934.26
    n-butyl acetate 408.56
    n-octanol 70.86
    chloroform 1179.42
    n-propyl acetate 175.68
    acetic acid 589.19
    dichloromethane 1204.56
    cyclohexanone 577.35
    propylene glycol 145.6
    isopropyl acetate 154.28
    DMAc 451.97
    2-ethoxyethanol 221.21
    isopentanol 202.83
    n-heptane 29.07
    ethyl formate 292.85
    1,2-dichloroethane 678.48
    n-hexanol 295.79
    2-methoxyethanol 473.11
    isobutyl acetate 116.46
    tetrachloromethane 182.38
    n-pentyl acetate 131.12
    transcutol 784.56
    n-heptanol 88.77
    ethylbenzene 67.75
    MIBK 115.15
    2-propoxyethanol 365.83
    tert-butanol 233.13
    MTBE 162.46
    2-butoxyethanol 169.04
    propionic acid 344.43
    o-xylene 102.95
    formic acid 183.76
    diethyl ether 172.82
    m-xylene 111.67
    p-xylene 98.43
    chlorobenzene 399.55
    dimethyl carbonate 111.97
    n-octane 8.93
    formamide 200.39
    cyclopentanone 551.49
    2-pentanone 226.98
    anisole 136.56
    cyclopentyl methyl ether 254.01
    gamma-butyrolactone 649.51
    1-methoxy-2-propanol 304.01
    pyridine 615.23
    3-pentanone 169.38
    furfural 695.85
    n-dodecane 8.22
    diethylene glycol 294.51
    diisopropyl ether 43.98
    tert-amyl alcohol 175.61
    acetylacetone 262.86
    n-hexadecane 9.45
    acetophenone 151.63
    methyl propionate 243.74
    isopentyl acetate 277.86
    trichloroethylene 1386.09
    n-nonanol 61.56
    cyclohexanol 252.68
    benzyl alcohol 165.97
    2-ethylhexanol 163.32
    isooctanol 68.99
    dipropyl ether 151.1
    1,2-dichlorobenzene 353.23
    ethyl lactate 92.07
    propylene carbonate 453.46
    n-methylformamide 376.6
    2-pentanol 143.64
    n-pentane 21.98
    1-propoxy-2-propanol 274.59
    1-methoxy-2-propyl acetate 252.17
    2-(2-methoxypropoxy) propanol 150.25
    mesitylene 65.34
    ε-caprolactone 430.38
    p-cymene 74.26
    epichlorohydrin 622.73
    1,1,1-trichloroethane 515.29
    2-aminoethanol 213.21
    morpholine-4-carbaldehyde 495.84
    sulfolane 762.09
    2,2,4-trimethylpentane 17.18
    2-methyltetrahydrofuran 370.72
    n-hexyl acetate 157.69
    isooctane 11.25
    2-(2-butoxyethoxy)ethanol 216.27
    sec-butyl acetate 95.1
    tert-butyl acetate 138.77
    decalin 26.54
    glycerin 210.09
    diglyme 374.42
    acrylic acid 331.25
    isopropyl myristate 58.92
    n-butyric acid 532.47
    acetyl acetate 197.05
    di(2-ethylhexyl) phthalate 83.99
    ethyl propionate 130.32
    nitromethane 614.17
    1,2-diethoxyethane 246.13
    benzonitrile 307.31
    trioctyl phosphate 58.37
    1-bromopropane 331.2
    gamma-valerolactone 639.79
    n-decanol 48.98
    triethyl phosphate 86.49
    4-methyl-2-pentanol 77.61
    propionitrile 263.04
    vinylene carbonate 437.9
    1,1,2-trichlorotrifluoroethane 573.92
    DMS 144.68
    cumene 51.57
    2-octanol 49.82
    2-hexanone 153.22
    octyl acetate 81.07
    limonene 127.05
    1,2-dimethoxyethane 330.41
    ethyl orthosilicate 84.43
    tributyl phosphate 77.06
    diacetone alcohol 165.18
    N,N-dimethylaniline 100.17
    acrylonitrile 369.31
    aniline 285.47
    1,3-propanediol 274.66
    bromobenzene 418.79
    dibromomethane 746.69
    1,1,2,2-tetrachloroethane 988.38
    2-methyl-cyclohexyl acetate 140.52
    tetrabutyl urea 106.85
    diisobutyl methanol 79.89
    2-phenylethanol 207.73
    styrene 106.29
    dioctyl adipate 101.06
    dimethyl sulfate 200.08
    ethyl butyrate 203.83
    methyl lactate 144.25
    butyl lactate 122.11
    diethyl carbonate 136.42
    propanediol butyl ether 150.76
    triethyl orthoformate 132.57
    p-tert-butyltoluene 65.21
    methyl 4-tert-butylbenzoate 129.27
    morpholine 463.49
    tert-butylamine 149.11
    n-dodecanol 40.81
    dimethoxymethane 281.58
    ethylene carbonate 353.44
    cyrene 140.58
    2-ethoxyethyl acetate 182.64
    2-ethylhexyl acetate 213.65
    1,2,4-trichlorobenzene 378.31
    4-methylpyridine 503.41
    dibutyl ether 98.19
    2,6-dimethyl-4-heptanol 79.89
    DEF 356.93
    dimethyl isosorbide 257.59
    tetrachloroethylene 706.7
    eugenol 141.16
    triacetin 136.47
    span 80 147.64
    1,4-butanediol 112.1
    1,1-dichloroethane 549.66
    2-methyl-1-pentanol 155.6
    methyl formate 290.19
    2-methyl-1-butanol 211.62
    n-decane 12.04
    butyronitrile 291.84
    3,7-dimethyl-1-octanol 81.13
    1-chlorooctane 57.41
    1-chlorotetradecane 26.63
    n-nonane 11.31
    undecane 9.67
    tert-butylcyclohexane 22.49
    cyclooctane 16.03
    cyclopentanol 267.86
    tetrahydropyran 407.08
    tert-amyl methyl ether 114.8
    2,5,8-trioxanonane 263.9
    1-hexene 90.66
    2-isopropoxyethanol 135.11
    2,2,2-trifluoroethanol 161.71
    methyl butyrate 219.52

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction