2-Butyl-5-ethyl-4-methylthiazole

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  • Identifiers

    CAS number
    86290-20-2

    Molecular formula
    C10H17NS

    SMILES
    CCCCC1=NC(=C(S1)CC)C

    Safety labels

  • Odor profile

    Fragrance
    Green 82.79%
    Nutty 59.09%
    Vegetable 57.53%
    Roasted 55.16%
    Fruity 48.88%
    Earthy 46.46%
    Meaty 45.24%
    Sulfurous 32.28%
    Burnt 31.95%
    Tropical 31.38%

     

    Flavor
    Green 78.99%
    Earthy 51.84%
    Nutty 44.67%
    Vegetable 43.29%
    Pepper 41.23%
    Roasted 39.94%
    Raw 34.19%
    Meaty 34.01%
    Herbal 33.59%
    Burnt 29.7%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.9

    pKa est.
    7.76 (neutral)

    Molecular weight
    183.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    244°C

    Flash point

    • 80.73 ˚C est.

  • Synonyms

    • 2-BUTYL-5-ETHYL-4-METHYL-1,3-THIAZOLE
    • 2-Butyl-5-ethyl-4-methylthiazole
    • DTXSID80717604
    • RefChem:258050
    • DTXCID90668350
    • 86290-20-2
    • DLQAOPSTXFKJFN-UHFFFAOYSA-N
    • 2-butyl-4-methyl-5-ethylthiazole
    • 2-butyl-5-ethyl-4-methyl-thiazole
    • AKOS006371005
    • 86290-20-2

  • Applications

    2-Butyl-5-ethyl-4-methylthiazole (CAS 86290-20-2) is primarily used as an aroma chemical in perfumery and flavor formulations, contributing nutty and roasted notes to fragrances and taste profiles. It is commonly evaluated for use as a fragrance ingredient in cosmetics and personal care products and can serve as an odorant in household products such as air fresheners and cleaners. In industrial manufacturing, the compound may function as a specialty aroma intermediate or building block for flavor/fragrance development and related syntheses. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 688.95
    methanol 627.43
    isopropanol 666.98
    water 0.2
    ethyl acetate 1172.78
    n-propanol 702.19
    acetone 1689.11
    n-butanol 812.32
    acetonitrile 783.46
    DMF 2266.94
    toluene 1379.11
    isobutanol 714.22
    1,4-dioxane 2593.4
    methyl acetate 1014.4
    THF 3229.39
    2-butanone 1437.72
    n-pentanol 646.65
    sec-butanol 724.9
    n-hexane 319.69
    ethylene glycol 84.76
    NMP 2228.66
    cyclohexane 719.05
    DMSO 1385.08
    n-butyl acetate 1646.03
    n-octanol 473.19
    chloroform 3705.32
    n-propyl acetate 881.01
    acetic acid 613.51
    dichloromethane 2871.39
    cyclohexanone 3011.77
    propylene glycol 164.23
    isopropyl acetate 910.02
    DMAc 1614.88
    2-ethoxyethanol 628.18
    isopentanol 871.66
    n-heptane 229.19
    ethyl formate 640.08
    1,2-dichloroethane 2065.32
    n-hexanol 1068.92
    2-methoxyethanol 934.47
    isobutyl acetate 750.92
    tetrachloromethane 811.79
    n-pentyl acetate 907.18
    transcutol 1934.43
    n-heptanol 454.97
    ethylbenzene 617.75
    MIBK 830.45
    2-propoxyethanol 1177.71
    tert-butanol 876.81
    MTBE 1359.71
    2-butoxyethanol 625.35
    propionic acid 498.91
    o-xylene 685.74
    formic acid 98.71
    diethyl ether 1458.07
    m-xylene 762.69
    p-xylene 865.32
    chlorobenzene 1686.23
    dimethyl carbonate 414.45
    n-octane 116.09
    formamide 169.29
    cyclopentanone 2584.84
    2-pentanone 1321.78
    anisole 946.67
    cyclopentyl methyl ether 1691.98
    gamma-butyrolactone 2228.09
    1-methoxy-2-propanol 784.1
    pyridine 2283.97
    3-pentanone 1075.6
    furfural 1728.22
    n-dodecane 87.44
    diethylene glycol 531.11
    diisopropyl ether 510.34
    tert-amyl alcohol 811.41
    acetylacetone 1348.18
    n-hexadecane 104.74
    acetophenone 852.48
    methyl propionate 839.74
    isopentyl acetate 1477.53
    trichloroethylene 3494.31
    n-nonanol 413.02
    cyclohexanol 1204.95
    benzyl alcohol 701.88
    2-ethylhexanol 706.11
    isooctanol 414.05
    dipropyl ether 879.97
    1,2-dichlorobenzene 1296.44
    ethyl lactate 282.61
    propylene carbonate 1308.08
    n-methylformamide 564.12
    2-pentanol 639.13
    n-pentane 244.64
    1-propoxy-2-propanol 920.52
    1-methoxy-2-propyl acetate 1097.72
    2-(2-methoxypropoxy) propanol 593.76
    mesitylene 525.04
    ε-caprolactone 1896.24
    p-cymene 402.11
    epichlorohydrin 2402.42
    1,1,1-trichloroethane 2218.51
    2-aminoethanol 212.37
    morpholine-4-carbaldehyde 1885.53
    sulfolane 2312.17
    2,2,4-trimethylpentane 153.44
    2-methyltetrahydrofuran 2578.29
    n-hexyl acetate 1145.04
    isooctane 122.07
    2-(2-butoxyethoxy)ethanol 790.2
    sec-butyl acetate 667.83
    tert-butyl acetate 987.4
    decalin 280.02
    glycerin 230.48
    diglyme 1468.03
    acrylic acid 405.44
    isopropyl myristate 465.02
    n-butyric acid 986.42
    acetyl acetate 788.94
    di(2-ethylhexyl) phthalate 422.12
    ethyl propionate 666.15
    nitromethane 932.9
    1,2-diethoxyethane 1340.83
    benzonitrile 1237.61
    trioctyl phosphate 299.32
    1-bromopropane 1466.39
    gamma-valerolactone 2557.03
    n-decanol 307.02
    triethyl phosphate 365.34
    4-methyl-2-pentanol 420.94
    propionitrile 894.05
    vinylene carbonate 1126.27
    1,1,2-trichlorotrifluoroethane 1131.69
    DMS 742.4
    cumene 404.19
    2-octanol 402.81
    2-hexanone 1040.74
    octyl acetate 552.33
    limonene 691.71
    1,2-dimethoxyethane 1718.95
    ethyl orthosilicate 385.86
    tributyl phosphate 396.38
    diacetone alcohol 760.09
    N,N-dimethylaniline 681.22
    acrylonitrile 864.89
    aniline 1086.27
    1,3-propanediol 436.52
    bromobenzene 2033.66
    dibromomethane 2107.45
    1,1,2,2-tetrachloroethane 2921.4
    2-methyl-cyclohexyl acetate 759.07
    tetrabutyl urea 523.68
    diisobutyl methanol 391.26
    2-phenylethanol 837.19
    styrene 895.08
    dioctyl adipate 537.28
    dimethyl sulfate 621.92
    ethyl butyrate 846.58
    methyl lactate 323.76
    butyl lactate 532.89
    diethyl carbonate 538.28
    propanediol butyl ether 513.61
    triethyl orthoformate 600.78
    p-tert-butyltoluene 402.38
    methyl 4-tert-butylbenzoate 654.08
    morpholine 2410.75
    tert-butylamine 667.48
    n-dodecanol 247.06
    dimethoxymethane 1271.77
    ethylene carbonate 1041.65
    cyrene 643.37
    2-ethoxyethyl acetate 1003.69
    2-ethylhexyl acetate 1256.69
    1,2,4-trichlorobenzene 1461.33
    4-methylpyridine 2624.02
    dibutyl ether 861.07
    2,6-dimethyl-4-heptanol 391.26
    DEF 1452.95
    dimethyl isosorbide 1207.17
    tetrachloroethylene 1890.17
    eugenol 679.72
    triacetin 760.09
    span 80 632.38
    1,4-butanediol 210.32
    1,1-dichloroethane 2167.48
    2-methyl-1-pentanol 716.58
    methyl formate 512.69
    2-methyl-1-butanol 805.04
    n-decane 147.44
    butyronitrile 1140.84
    3,7-dimethyl-1-octanol 495.99
    1-chlorooctane 515.68
    1-chlorotetradecane 214.91
    n-nonane 153.92
    undecane 107.68
    tert-butylcyclohexane 237.45
    cyclooctane 227.85
    cyclopentanol 1044.41
    tetrahydropyran 2900.08
    tert-amyl methyl ether 962.07
    2,5,8-trioxanonane 982.49
    1-hexene 911.17
    2-isopropoxyethanol 527.01
    2,2,2-trifluoroethanol 202.04
    methyl butyrate 964.42

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction