2-Butyl-5-[2-(4-hydroxy-3-methoxyphenyl)ethyl]furan

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  • Identifiers

    CAS number
    143114-90-3

    Molecular formula
    C17H22O3

    SMILES
    CCCCC1=CC=C(O1)CCC2=CC(=C(C=C2)O)OC

    Safety labels

  • Odor profile

    Fragrance
    Spicy 62.58%
    Sweet 48.2%
    Phenolic 43.0%
    Fruity 40.05%
    Vanilla 38.8%
    Floral 38.43%
    Burnt 36.71%
    Smoky 36.59%
    Balsamic 35.15%
    Roasted 26.59%

     

    Flavor
    Spicy 53.15%
    Phenolic 41.57%
    Sweet 38.72%
    Spice 37.86%
    Smoky 37.27%
    Earthy 35.79%
    Burnt 33.05%
    Musty 30.22%
    Creamy 29.9%
    Coconut 29.83%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.9

    pKa est.
    9.75 (weak base)

    Molecular weight
    274.35 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    443°C

    Flash point

    • 171.33 ˚C est.

  • Synonyms

    • 2-Butyl-5-[2-(4-hydroxy-3-methoxyphenyl)ethyl]furan
    • 143114-90-3
    • 4-[2-(5-butylfuran-2-yl)ethyl]-2-methoxyphenol
    • Phenol, 4-[2-(5-butyl-2-furanyl)ethyl]-2-methoxy-
    • 4-[2-(5-butyl-2-furyl)ethyl]-2-methoxy-phenol
    • SCHEMBL8236421
    • CHEMBL2071438
    • DTXSID40451416
    • CHEBI:174626
    • 4-[2-(5-butyl-2-furanyl)ethyl]-2-methoxyphenol
    • 4-[2-(5-butyluran-2-yl)ethyl]-2-methoxyphenol
    • 4-[2-(5-Butyl-2-furanyl)ethyl]-2-methoxyphenol, 9CI
    • 143114-90-3

  • Applications

    2-Butyl-5-[2-(4-hydroxy-3-methoxyphenyl)ethyl]furan (CAS 143114-90-3) is used primarily as an odorant in fragrance formulations and flavor applications. It is also evaluated as an intermediate in the synthesis of fragrance and flavor compounds for the food and beverage sector. In cosmetics and personal care, it may be used as a fragrance additive in products such as creams and cleansers. In household and cleaning products, it can contribute to scent profiles in detergents and cleaners. Additionally, it may serve as an intermediate for the synthesis of fragrance-related compounds used in polymers, coatings, and inks, depending on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1142.12
    methanol 1379.96
    isopropanol 593.94
    water 0.06
    ethyl acetate 879.24
    n-propanol 733.01
    acetone 745.72
    n-butanol 479.37
    acetonitrile 475.16
    DMF 323.8
    toluene 179.81
    isobutanol 356.88
    1,4-dioxane 1539.48
    methyl acetate 590.97
    THF 1577.46
    2-butanone 608.62
    n-pentanol 316.95
    sec-butanol 401.62
    n-hexane 4.71
    ethylene glycol 75.32
    NMP 73.57
    cyclohexane 25.9
    DMSO 1049.56
    n-butyl acetate 247.27
    n-octanol 75.76
    chloroform 1166.32
    n-propyl acetate 318.43
    acetic acid 343.68
    dichloromethane 1436.4
    cyclohexanone 498.19
    propylene glycol 176.36
    isopropyl acetate 352.87
    DMAc 359.09
    2-ethoxyethanol 803.44
    isopentanol 293.78
    n-heptane 5.95
    ethyl formate 328.46
    1,2-dichloroethane 904.86
    n-hexanol 190.27
    2-methoxyethanol 1120.8
    isobutyl acetate 222.25
    tetrachloromethane 65.71
    n-pentyl acetate 142.1
    transcutol 1156.05
    n-heptanol 77.46
    ethylbenzene 80.88
    MIBK 221.71
    2-propoxyethanol 503.55
    tert-butanol 590.51
    MTBE 475.97
    2-butoxyethanol 202.5
    propionic acid 226.12
    o-xylene 71.45
    formic acid 84.01
    diethyl ether 674.67
    m-xylene 83.37
    p-xylene 98.87
    chlorobenzene 208.88
    dimethyl carbonate 124.75
    n-octane 6.29
    formamide 206.07
    cyclopentanone 426.01
    2-pentanone 447.58
    anisole 235.0
    cyclopentyl methyl ether 289.54
    gamma-butyrolactone 443.18
    1-methoxy-2-propanol 645.21
    pyridine 606.08
    3-pentanone 267.93
    furfural 364.81
    n-dodecane 8.09
    diethylene glycol 338.52
    diisopropyl ether 73.52
    tert-amyl alcohol 338.4
    acetylacetone 494.39
    n-hexadecane 9.27
    acetophenone 184.58
    methyl propionate 383.94
    isopentyl acetate 243.67
    trichloroethylene 1055.63
    n-nonanol 76.33
    cyclohexanol 258.76
    benzyl alcohol 214.26
    2-ethylhexanol 82.82
    isooctanol 69.97
    dipropyl ether 122.73
    1,2-dichlorobenzene 163.2
    ethyl lactate 108.07
    propylene carbonate 228.27
    n-methylformamide 223.39
    2-pentanol 219.05
    n-pentane 4.42
    1-propoxy-2-propanol 243.13
    1-methoxy-2-propyl acetate 269.6
    2-(2-methoxypropoxy) propanol 186.1
    mesitylene 45.73
    ε-caprolactone 384.15
    p-cymene 41.94
    epichlorohydrin 1057.83
    1,1,1-trichloroethane 432.18
    2-aminoethanol 230.32
    morpholine-4-carbaldehyde 335.52
    sulfolane 314.11
    2,2,4-trimethylpentane 8.04
    2-methyltetrahydrofuran 617.91
    n-hexyl acetate 163.13
    isooctane 6.49
    2-(2-butoxyethoxy)ethanol 295.55
    sec-butyl acetate 204.99
    tert-butyl acetate 305.75
    decalin 12.94
    glycerin 175.82
    diglyme 625.85
    acrylic acid 137.33
    isopropyl myristate 73.46
    n-butyric acid 446.62
    acetyl acetate 314.22
    di(2-ethylhexyl) phthalate 67.68
    ethyl propionate 232.74
    nitromethane 633.12
    1,2-diethoxyethane 430.04
    benzonitrile 197.99
    trioctyl phosphate 46.81
    1-bromopropane 393.63
    gamma-valerolactone 664.47
    n-decanol 59.36
    triethyl phosphate 74.84
    4-methyl-2-pentanol 102.27
    propionitrile 348.47
    vinylene carbonate 219.5
    1,1,2-trichlorotrifluoroethane 328.59
    DMS 156.36
    cumene 49.41
    2-octanol 58.03
    2-hexanone 272.44
    octyl acetate 89.44
    limonene 55.42
    1,2-dimethoxyethane 978.7
    ethyl orthosilicate 79.79
    tributyl phosphate 63.05
    diacetone alcohol 285.29
    N,N-dimethylaniline 97.64
    acrylonitrile 363.94
    aniline 200.67
    1,3-propanediol 479.91
    bromobenzene 227.11
    dibromomethane 800.03
    1,1,2,2-tetrachloroethane 767.96
    2-methyl-cyclohexyl acetate 122.11
    tetrabutyl urea 78.83
    diisobutyl methanol 58.66
    2-phenylethanol 164.81
    styrene 111.22
    dioctyl adipate 110.4
    dimethyl sulfate 132.73
    ethyl butyrate 168.12
    methyl lactate 119.48
    butyl lactate 104.55
    diethyl carbonate 125.55
    propanediol butyl ether 156.61
    triethyl orthoformate 120.11
    p-tert-butyltoluene 40.86
    methyl 4-tert-butylbenzoate 134.31
    morpholine 1576.02
    tert-butylamine 224.46
    n-dodecanol 47.97
    dimethoxymethane 685.57
    ethylene carbonate 219.98
    cyrene 137.72
    2-ethoxyethyl acetate 273.97
    2-ethylhexyl acetate 159.82
    1,2,4-trichlorobenzene 166.64
    4-methylpyridine 381.5
    dibutyl ether 123.75
    2,6-dimethyl-4-heptanol 58.66
    DEF 265.69
    dimethyl isosorbide 259.75
    tetrachloroethylene 405.38
    eugenol 146.24
    triacetin 173.5
    span 80 135.59
    1,4-butanediol 176.82
    1,1-dichloroethane 691.34
    2-methyl-1-pentanol 212.3
    methyl formate 184.19
    2-methyl-1-butanol 248.71
    n-decane 12.37
    butyronitrile 386.26
    3,7-dimethyl-1-octanol 82.79
    1-chlorooctane 56.55
    1-chlorotetradecane 25.47
    n-nonane 10.39
    undecane 9.66
    tert-butylcyclohexane 11.79
    cyclooctane 5.71
    cyclopentanol 212.99
    tetrahydropyran 1211.69
    tert-amyl methyl ether 235.85
    2,5,8-trioxanonane 391.75
    1-hexene 50.48
    2-isopropoxyethanol 406.7
    2,2,2-trifluoroethanol 67.35
    methyl butyrate 308.26

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction