2-Butanol, 1-methoxy-

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  • Identifiers

    CAS number
    53778-73-7

    Molecular formula
    C5H12O2

    SMILES
    CCC(COC)O

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Ethereal 54.92%
    Fruity 53.97%
    Alcoholic 50.01%
    Sweet 47.19%
    Solvent 40.94%
    Fermented 39.14%
    Oily 35.88%
    Buttery 34.12%
    Musty 30.23%
    Caramellic 29.33%

     

    Flavor
    Alcoholic 47.6%
    Bitter 37.05%
    Sweet 35.51%
    Odorless 33.07%
    Musty 32.39%
    Oily 30.47%
    Fermented 26.69%
    Onion 26.63%
    Fusel 26.53%
    Ether 26.51%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.4

    pKa est.
    7.73 (neutral)

    Molecular weight
    104.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    138°C

    Flash point

    • 40.15 ˚C est.

  • Synonyms

    • 1-METHOXY-2-BUTANOL
    • 1-Methoxybutan-2-ol
    • 53778-73-7
    • 2-Butanol, 1-methoxy-
    • EINECS 258-763-2
    • CSZZMFWKAQEMPB-UHFFFAOYSA-
    • DTXSID00866360
    • RefChem:467349
    • DTXCID10814650
    • 258-763-2
    • InChI=1/C5H12O2/c1-3-5(6)4-7-2/h5-6H,3-4H2,1-2H3
    • MFCD00059143
    • 1,2-Butanediol 1-Monomethyl Ether
    • rac-1-methoxy-2-butanol
    • SCHEMBL283332
    • 1-Methoxy-2-butanol, 97%
    • SCHEMBL2642368
    • SCHEMBL5070460
    • SCHEMBL7536563
    • ALBB-025835
    • (2R)-1-METHOXYBUTAN-2-OL
    • SBB072708
    • AKOS009156938
    • LS-08706
    • CS-0199441
    • M0747
    • NS00057712
    • ST45028985
    • E78134
    • EN300-1256792
    • 53778-73-7

  • Applications

    2-Butanol, 1-methoxy- (CAS 53778-73-7) is a glycol ether used as a solvent and co-solvent in coatings, inks, and adhesives, and it has a role in cleaning and industrial wash formulations; it also serves as a chemical intermediate for the synthesis of ethers and related derivatives; in solvent or additive form, it can be used for plastics and polymer systems as a processing aid or solvent; it is considered for cosmetic and personal care applications under regulatory control, and may be evaluated for electronics and specialty cleaning applications in industrial manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1026.51
    methanol 1723.35
    isopropanol 652.32
    water 73.0
    ethyl acetate 153.39
    n-propanol 742.51
    acetone 231.86
    n-butanol 583.06
    acetonitrile 271.06
    DMF 367.48
    toluene 25.48
    isobutanol 468.29
    1,4-dioxane 440.45
    methyl acetate 190.69
    THF 495.23
    2-butanone 180.26
    n-pentanol 282.79
    sec-butanol 539.78
    n-hexane 18.46
    ethylene glycol 602.29
    NMP 338.0
    cyclohexane 36.28
    DMSO 566.96
    n-butyl acetate 141.39
    n-octanol 127.71
    chloroform 465.54
    n-propyl acetate 101.94
    acetic acid 1507.46
    dichloromethane 377.21
    cyclohexanone 300.46
    propylene glycol 587.11
    isopropyl acetate 73.58
    DMAc 232.79
    2-ethoxyethanol 473.39
    isopentanol 309.69
    n-heptane 27.93
    ethyl formate 194.78
    1,2-dichloroethane 174.33
    n-hexanol 309.21
    2-methoxyethanol 924.52
    isobutyl acetate 65.29
    tetrachloromethane 111.61
    n-pentyl acetate 85.71
    transcutol 694.04
    n-heptanol 139.24
    ethylbenzene 19.7
    MIBK 68.21
    2-propoxyethanol 442.88
    tert-butanol 603.11
    MTBE 173.35
    2-butoxyethanol 245.62
    propionic acid 636.06
    o-xylene 29.77
    formic acid 880.99
    diethyl ether 142.38
    m-xylene 23.75
    p-xylene 30.72
    chlorobenzene 74.36
    dimethyl carbonate 35.81
    n-octane 9.26
    formamide 486.91
    cyclopentanone 332.13
    2-pentanone 115.6
    anisole 66.81
    cyclopentyl methyl ether 176.08
    gamma-butyrolactone 424.93
    1-methoxy-2-propanol 463.2
    pyridine 199.1
    3-pentanone 80.47
    furfural 378.5
    n-dodecane 8.08
    diethylene glycol 504.52
    diisopropyl ether 32.94
    tert-amyl alcohol 468.25
    acetylacetone 108.88
    n-hexadecane 8.41
    acetophenone 77.78
    methyl propionate 115.47
    isopentyl acetate 117.92
    trichloroethylene 359.21
    n-nonanol 101.26
    cyclohexanol 373.52
    benzyl alcohol 122.2
    2-ethylhexanol 152.41
    isooctanol 109.27
    dipropyl ether 95.08
    1,2-dichlorobenzene 80.1
    ethyl lactate 97.26
    propylene carbonate 208.63
    n-methylformamide 366.87
    2-pentanol 269.27
    n-pentane 24.53
    1-propoxy-2-propanol 309.79
    1-methoxy-2-propyl acetate 117.18
    2-(2-methoxypropoxy) propanol 180.45
    mesitylene 20.09
    ε-caprolactone 267.45
    p-cymene 34.22
    epichlorohydrin 334.4
    1,1,1-trichloroethane 157.18
    2-aminoethanol 810.53
    morpholine-4-carbaldehyde 386.24
    sulfolane 483.83
    2,2,4-trimethylpentane 19.37
    2-methyltetrahydrofuran 368.61
    n-hexyl acetate 123.26
    isooctane 11.91
    2-(2-butoxyethoxy)ethanol 253.03
    sec-butyl acetate 56.93
    tert-butyl acetate 84.62
    decalin 15.42
    glycerin 747.0
    diglyme 401.3
    acrylic acid 547.4
    isopropyl myristate 46.26
    n-butyric acid 591.44
    acetyl acetate 95.4
    di(2-ethylhexyl) phthalate 64.68
    ethyl propionate 67.77
    nitromethane 705.33
    1,2-diethoxyethane 137.07
    benzonitrile 126.3
    trioctyl phosphate 54.6
    1-bromopropane 107.85
    gamma-valerolactone 414.59
    n-decanol 70.59
    triethyl phosphate 56.46
    4-methyl-2-pentanol 108.54
    propionitrile 223.46
    vinylene carbonate 190.72
    1,1,2-trichlorotrifluoroethane 465.1
    DMS 74.08
    cumene 22.66
    2-octanol 83.83
    2-hexanone 97.74
    octyl acetate 64.45
    limonene 62.84
    1,2-dimethoxyethane 378.39
    ethyl orthosilicate 58.04
    tributyl phosphate 61.15
    diacetone alcohol 173.89
    N,N-dimethylaniline 54.29
    acrylonitrile 273.78
    aniline 122.25
    1,3-propanediol 839.16
    bromobenzene 54.68
    dibromomethane 241.59
    1,1,2,2-tetrachloroethane 310.71
    2-methyl-cyclohexyl acetate 93.17
    tetrabutyl urea 69.07
    diisobutyl methanol 79.28
    2-phenylethanol 117.23
    styrene 24.89
    dioctyl adipate 77.58
    dimethyl sulfate 77.81
    ethyl butyrate 97.27
    methyl lactate 138.51
    butyl lactate 110.99
    diethyl carbonate 62.08
    propanediol butyl ether 262.08
    triethyl orthoformate 83.99
    p-tert-butyltoluene 33.81
    methyl 4-tert-butylbenzoate 106.02
    morpholine 552.98
    tert-butylamine 330.07
    n-dodecanol 53.57
    dimethoxymethane 147.87
    ethylene carbonate 157.24
    cyrene 162.97
    2-ethoxyethyl acetate 104.23
    2-ethylhexyl acetate 90.07
    1,2,4-trichlorobenzene 106.15
    4-methylpyridine 142.34
    dibutyl ether 75.14
    2,6-dimethyl-4-heptanol 79.28
    DEF 169.24
    dimethyl isosorbide 213.64
    tetrachloroethylene 270.23
    eugenol 127.88
    triacetin 124.11
    span 80 192.23
    1,4-butanediol 339.48
    1,1-dichloroethane 174.29
    2-methyl-1-pentanol 202.9
    methyl formate 229.44
    2-methyl-1-butanol 349.97
    n-decane 12.85
    butyronitrile 234.6
    3,7-dimethyl-1-octanol 113.82
    1-chlorooctane 48.42
    1-chlorotetradecane 19.51
    n-nonane 12.9
    undecane 9.62
    tert-butylcyclohexane 18.31
    cyclooctane 11.18
    cyclopentanol 456.51
    tetrahydropyran 345.85
    tert-amyl methyl ether 125.05
    2,5,8-trioxanonane 275.1
    1-hexene 53.04
    2-isopropoxyethanol 262.09
    2,2,2-trifluoroethanol 377.73
    methyl butyrate 121.78

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction