2-Amino-5-methylphenol

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  • Identifiers

    CAS number
    2835-98-5

    Molecular formula
    C7H9NO

    SMILES
    CC1=CC(=C(C=C1)N)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Phenolic 68.45%
    Smoky 48.04%
    Burnt 41.74%
    Medicinal 39.49%
    Sweet 35.57%
    Spicy 32.83%
    Meaty 31.44%
    Animal 30.1%
    Odorless 27.86%
    Vanilla 27.42%

     

    Flavor
    Phenolic 65.08%
    Medicinal 45.47%
    Mild 33.96%
    Bitter 32.91%
    Phenol 31.8%
    Meaty 31.41%
    Smoke 30.71%
    Sweet 30.02%
    Medical 28.43%
    Smoky 28.42%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.2

    pKa est.
    7.29 (neutral)

    Molecular weight
    123.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    253°C

    Flash point

    • 122.84 ˚C est.

  • Synonyms

    • 2-Amino-5-methylphenol
    • 6-Amino-m-cresol
    • 2835-98-5
    • 2-Hydroxy-4-methylaniline
    • Phenol, 2-amino-5-methyl-
    • 4-Amino-3-hydroxytoluene
    • QCG4ES2A26
    • NSC-322874
    • DTXSID20182594
    • RefChem:85284
    • DTXCID60105085
    • 220-620-7
    • 6-Amino-3-methylphenol
    • 6-AMINO-3-CRESOL
    • MFCD00007693
    • Cetilistat Impurity 4
    • 5-methyl-2-aminophenol
    • EINECS 220-620-7
    • UNII-QCG4ES2A26
    • NSC 322874
    • CCRIS 8309
    • NSC322874
    • Cetilistat Impurity A
    • m-Cresol, 6-amino-
    • 2-amino-5-methyl-phenol
    • 2-hydroxy 4-methyl aniline
    • 2-hydroxy-4-methyl aniline
    • 2-hydroxy-4-methyl-aniline
    • 2A5MP
    • Oprea1_628116
    • SCHEMBL33821
    • BIDD:GT0077
    • SCHEMBL3855541
    • SCHEMBL9478896
    • 2-Amino-5-methylphenol, 98%
    • SCHEMBL27606355
    • SCHEMBL29356215
    • KUC106689N
    • BBL002991
    • STK378547
    • AKOS000120833
    • AB00890
    • CS-W013539
    • EBC-151097
    • FA67402
    • NCGC00332263-01
    • BP-12759
    • DS-18142
    • KSC-11-207-2
    • SY018794
    • DB-020478
    • A0919
    • NS00013354
    • ST50908773
    • EN300-20860
    • O10653
    • AB01274036-03
    • F043441
    • doi:10.14272/HCPJEHJGFKWRFM-UHFFFAOYSA-N.1
    • Q27287198
    • Z104483986
    • InChI=1/C7H9NO/c1-5-2-3-6(8)7(9)4-5/h2-4,9H,8H2,1H
    • 2835-98-5

  • Applications

    2-Amino-5-methylphenol, CAS number: 2835-98-5, is primarily used as an organic building block and chemical intermediate in industrial synthesis. In practice, it serves as a precursor for dye and pigment chemistry, enabling the production of colorants used in coatings, inks, and textiles. It is also employed as a reactive intermediate in the manufacture of polymer additives and functional materials for plastics and coatings. In pharmaceutical and agrochemical research, the compound is often evaluated as a synthetic building block for more complex molecules. Additionally, it may undergo further functionalization for niche specialty chemicals in research and development, with exact use governed by formulation needs and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 59.78
    methanol 83.44
    isopropanol 44.45
    water 8.14
    ethyl acetate 45.06
    n-propanol 38.44
    acetone 91.52
    n-butanol 30.66
    acetonitrile 55.44
    DMF 57.58
    toluene 3.94
    isobutanol 26.01
    1,4-dioxane 137.2
    methyl acetate 60.65
    THF 301.99
    2-butanone 68.25
    n-pentanol 28.72
    sec-butanol 28.88
    n-hexane 1.3
    ethylene glycol 24.45
    NMP 62.63
    cyclohexane 0.55
    DMSO 140.34
    n-butyl acetate 34.62
    n-octanol 26.32
    chloroform 16.75
    n-propyl acetate 27.9
    acetic acid 102.6
    dichloromethane 12.01
    cyclohexanone 54.56
    propylene glycol 21.02
    isopropyl acetate 25.23
    DMAc 82.35
    2-ethoxyethanol 74.69
    isopentanol 32.65
    n-heptane 3.09
    ethyl formate 40.15
    1,2-dichloroethane 10.95
    n-hexanol 58.75
    2-methoxyethanol 102.17
    isobutyl acetate 18.03
    tetrachloromethane 7.54
    n-pentyl acetate 22.98
    transcutol 92.81
    n-heptanol 41.18
    ethylbenzene 4.74
    MIBK 35.9
    2-propoxyethanol 106.02
    tert-butanol 75.2
    MTBE 47.28
    2-butoxyethanol 68.82
    propionic acid 52.88
    o-xylene 5.91
    formic acid 90.85
    diethyl ether 23.86
    m-xylene 7.96
    p-xylene 6.72
    chlorobenzene 8.78
    dimethyl carbonate 20.41
    n-octane 1.73
    formamide 99.43
    cyclopentanone 126.07
    2-pentanone 46.55
    anisole 21.75
    cyclopentyl methyl ether 52.32
    gamma-butyrolactone 143.49
    1-methoxy-2-propanol 69.55
    pyridine 26.69
    3-pentanone 25.61
    furfural 84.24
    n-dodecane 1.44
    diethylene glycol 86.64
    diisopropyl ether 9.08
    tert-amyl alcohol 52.24
    acetylacetone 53.88
    n-hexadecane 1.54
    acetophenone 21.87
    methyl propionate 36.44
    isopentyl acetate 31.62
    trichloroethylene 28.91
    n-nonanol 23.65
    cyclohexanol 18.62
    benzyl alcohol 19.8
    2-ethylhexanol 30.01
    isooctanol 32.2
    dipropyl ether 24.53
    1,2-dichlorobenzene 11.02
    ethyl lactate 20.26
    propylene carbonate 52.96
    n-methylformamide 61.12
    2-pentanol 22.04
    n-pentane 0.82
    1-propoxy-2-propanol 64.53
    1-methoxy-2-propyl acetate 44.04
    2-(2-methoxypropoxy) propanol 45.37
    mesitylene 6.24
    ε-caprolactone 45.1
    p-cymene 7.99
    epichlorohydrin 108.42
    1,1,1-trichloroethane 18.38
    2-aminoethanol 39.72
    morpholine-4-carbaldehyde 84.09
    sulfolane 118.71
    2,2,4-trimethylpentane 1.59
    2-methyltetrahydrofuran 107.91
    n-hexyl acetate 30.85
    isooctane 1.91
    2-(2-butoxyethoxy)ethanol 64.53
    sec-butyl acetate 16.51
    tert-butyl acetate 38.2
    decalin 1.31
    glycerin 53.02
    diglyme 103.25
    acrylic acid 43.12
    isopropyl myristate 13.02
    n-butyric acid 57.97
    acetyl acetate 24.75
    di(2-ethylhexyl) phthalate 15.82
    ethyl propionate 20.87
    nitromethane 178.26
    1,2-diethoxyethane 32.21
    benzonitrile 16.93
    trioctyl phosphate 14.99
    1-bromopropane 5.04
    gamma-valerolactone 128.49
    n-decanol 18.11
    triethyl phosphate 15.28
    4-methyl-2-pentanol 21.09
    propionitrile 24.82
    vinylene carbonate 40.21
    1,1,2-trichlorotrifluoroethane 64.66
    DMS 18.4
    cumene 6.01
    2-octanol 23.0
    2-hexanone 35.12
    octyl acetate 19.3
    limonene 10.74
    1,2-dimethoxyethane 107.27
    ethyl orthosilicate 15.33
    tributyl phosphate 13.85
    diacetone alcohol 63.47
    N,N-dimethylaniline 17.54
    acrylonitrile 35.66
    aniline 13.08
    1,3-propanediol 57.66
    bromobenzene 6.27
    dibromomethane 7.23
    1,1,2,2-tetrachloroethane 23.65
    2-methyl-cyclohexyl acetate 23.52
    tetrabutyl urea 18.85
    diisobutyl methanol 18.4
    2-phenylethanol 34.56
    styrene 4.0
    dioctyl adipate 16.99
    dimethyl sulfate 39.3
    ethyl butyrate 25.1
    methyl lactate 27.42
    butyl lactate 22.48
    diethyl carbonate 15.46
    propanediol butyl ether 38.74
    triethyl orthoformate 18.5
    p-tert-butyltoluene 8.72
    methyl 4-tert-butylbenzoate 35.63
    morpholine 102.32
    tert-butylamine 28.79
    n-dodecanol 13.6
    dimethoxymethane 62.1
    ethylene carbonate 32.22
    cyrene 44.96
    2-ethoxyethyl acetate 31.24
    2-ethylhexyl acetate 20.93
    1,2,4-trichlorobenzene 13.17
    4-methylpyridine 23.14
    dibutyl ether 14.97
    2,6-dimethyl-4-heptanol 18.4
    DEF 30.7
    dimethyl isosorbide 72.68
    tetrachloroethylene 20.38
    eugenol 39.76
    triacetin 25.5
    span 80 38.26
    1,4-butanediol 26.03
    1,1-dichloroethane 12.91
    2-methyl-1-pentanol 28.41
    methyl formate 61.1
    2-methyl-1-butanol 26.83
    n-decane 2.33
    butyronitrile 25.87
    3,7-dimethyl-1-octanol 21.94
    1-chlorooctane 10.22
    1-chlorotetradecane 3.86
    n-nonane 2.06
    undecane 1.78
    tert-butylcyclohexane 2.21
    cyclooctane 0.56
    cyclopentanol 34.91
    tetrahydropyran 50.91
    tert-amyl methyl ether 29.94
    2,5,8-trioxanonane 76.0
    1-hexene 5.09
    2-isopropoxyethanol 53.04
    2,2,2-trifluoroethanol 49.48
    methyl butyrate 30.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction