2-Amino-4-((2-hydroxyethyl)amino)anisole sulfate

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  • Identifiers

    CAS number
    83763-48-8

    Molecular formula
    C9H16N2O6S

    SMILES
    COC1=C(C=C(C=C1)NCCO)N.OS(=O)(=O)O

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 40.99%
    Savory 27.77%
    Sweet 27.56%
    Fishy 27.08%
    Meaty 26.74%
    Animal 23.03%
    Cheesy 21.75%
    Burnt 20.52%
    Vanilla 19.92%
    Cooling 19.87%

     

    Flavor
    Sweet 48.14%
    Bitter 41.61%
    Fruity 39.67%
    Mild 38.99%
    Odorless 33.35%
    Floral 23.92%
    Powdery 23.45%
    Meaty 23.26%
    Sweet-like 22.1%
    Smoked 21.41%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.12 (weak acid)

    Molecular weight
    280.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    438°C

    Flash point

    • 192.86 ˚C est.

  • Synonyms

    • 83763-48-8
    • 2-Amino-4-hydroxyethylaminoanisole sulfate
    • jarocol ahea
    • 2-((3-Amino-4-methoxyphenyl)amino)ethanol sulfate
    • COVASTYLE AHEAS
    • DTXSID30892455
    • UM91A54Z8G
    • 2-Amino-4-((2-hydroxyethyl)amino)anisole sulfate
    • 2-Amino-4-[(2-hydroxyethyl)amino]anisole Sulfate
    • ETHANOL, 2-((3-AMINO-4-METHOXYPHENYL)AMINO)-, SULFATE (1:1)
    • ETHANOL, 2-((3-AMINO-4-METHOXYPHENYL)AMINO)-, SULFATE (1:1) (SALT)
    • RefChem:85206
    • DTXCID201079640
    • 280-734-8
    • 5-(2-Hydroxyethylamino)-2-methoxylaniline sulfate
    • 2-Amino-4-hydroxyethylamino anisole sulfate
    • MFCD00467095
    • C9H16N2O6S
    • 2-(3-amino-4-methoxyanilino)ethanol;sulfuric acid
    • 2-[(3-amino-4-methoxyphenyl)amino]ethan-1-ol; sulfuric acid
    • 2-((3-Amino-4-methoxyphenyl)amino)ethanol sulfate;2-Amino-4-hydroxyethylaminoanisole sulfate
    • 2-AMINO-4-HYDROXYETHYLAMINOANISOLESULFATE
    • SCHEMBL143437
    • SCHEMBL29873108
    • MSK15596B
    • GWHLYFOWAINYAH-UHFFFAOYSA-N
    • AKOS015856651
    • AC-8294
    • DS-0791
    • FA144360
    • DB-020432
    • CS-0150576
    • 763A488
    • 2-(3-amino-4-methoxy-anilino)ethanol;sulfuric acid
    • Q27291147
    • Sulfuric acid--2-(3-amino-4-methoxyanilino)ethan-1-ol (1/1)
    • Ethanol, 2-a[(3-aamino-a4-amethoxyphenyl)aamino]a-a, sulfate (1:1)
    • 83763-48-8

  • Applications

    2-Amino-4-((2-hydroxyethyl)amino)anisole sulfate (CAS 83763-48-8) is the water-soluble sulfate salt of a substituted aminophenyl ether used primarily as an intermediate in dye and pigment synthesis. Practically, it serves as a building block for textile dye precursors and colorants for inks and coatings. It also functions as a precursor for polymer colorants used in plastics and coatings formulations. With its amino and hydroxyethyl functionality, it may participate in synthetic routes toward pharmaceutical intermediates, depending on process conditions and local regulation. The sulfate form enhances aqueous solubility and process compatibility; use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 74.82
    methanol 225.25
    isopropanol 22.35
    water 49.86
    ethyl acetate 33.96
    n-propanol 38.85
    acetone 33.29
    n-butanol 29.27
    acetonitrile 30.28
    DMF 281.09
    toluene 2.6
    isobutanol 20.34
    1,4-dioxane 74.57
    methyl acetate 27.45
    THF 116.57
    2-butanone 17.4
    n-pentanol 17.18
    sec-butanol 16.13
    n-hexane 0.17
    ethylene glycol 184.43
    NMP 216.94
    cyclohexane 0.68
    DMSO 1108.5
    n-butyl acetate 13.9
    n-octanol 7.12
    chloroform 21.48
    n-propyl acetate 14.64
    acetic acid 598.43
    dichloromethane 35.09
    cyclohexanone 56.94
    propylene glycol 107.51
    isopropyl acetate 11.97
    DMAc 223.19
    2-ethoxyethanol 152.52
    isopentanol 20.98
    n-heptane 0.64
    ethyl formate 65.03
    1,2-dichloroethane 22.82
    n-hexanol 16.99
    2-methoxyethanol 339.14
    isobutyl acetate 7.96
    tetrachloromethane 5.06
    n-pentyl acetate 7.53
    transcutol 166.02
    n-heptanol 9.74
    ethylbenzene 1.38
    MIBK 9.81
    2-propoxyethanol 82.95
    tert-butanol 40.85
    MTBE 9.88
    2-butoxyethanol 38.26
    propionic acid 99.47
    o-xylene 3.71
    formic acid 873.61
    diethyl ether 6.64
    m-xylene 3.32
    p-xylene 1.94
    chlorobenzene 7.83
    dimethyl carbonate 27.47
    n-octane 0.32
    formamide 787.24
    cyclopentanone 99.79
    2-pentanone 15.03
    anisole 10.1
    cyclopentyl methyl ether 24.69
    gamma-butyrolactone 206.17
    1-methoxy-2-propanol 114.94
    pyridine 30.61
    3-pentanone 9.76
    furfural 213.9
    n-dodecane 0.3
    diethylene glycol 174.36
    diisopropyl ether 1.92
    tert-amyl alcohol 25.72
    acetylacetone 48.3
    n-hexadecane 0.33
    acetophenone 17.41
    methyl propionate 31.13
    isopentyl acetate 12.91
    trichloroethylene 50.17
    n-nonanol 6.85
    cyclohexanol 22.66
    benzyl alcohol 22.8
    2-ethylhexanol 8.8
    isooctanol 8.15
    dipropyl ether 6.62
    1,2-dichlorobenzene 10.2
    ethyl lactate 27.93
    propylene carbonate 89.07
    n-methylformamide 247.6
    2-pentanol 8.3
    n-pentane 0.25
    1-propoxy-2-propanol 40.48
    1-methoxy-2-propyl acetate 32.27
    2-(2-methoxypropoxy) propanol 36.75
    mesitylene 2.63
    ε-caprolactone 62.37
    p-cymene 3.37
    epichlorohydrin 134.14
    1,1,1-trichloroethane 12.28
    2-aminoethanol 172.83
    morpholine-4-carbaldehyde 204.83
    sulfolane 339.65
    2,2,4-trimethylpentane 0.45
    2-methyltetrahydrofuran 43.61
    n-hexyl acetate 10.65
    isooctane 0.28
    2-(2-butoxyethoxy)ethanol 52.54
    sec-butyl acetate 6.58
    tert-butyl acetate 15.79
    decalin 0.47
    glycerin 278.52
    diglyme 105.51
    acrylic acid 139.51
    isopropyl myristate 4.26
    n-butyric acid 120.96
    acetyl acetate 33.35
    di(2-ethylhexyl) phthalate 11.43
    ethyl propionate 11.5
    nitromethane 646.36
    1,2-diethoxyethane 18.34
    benzonitrile 17.9
    trioctyl phosphate 8.0
    1-bromopropane 4.37
    gamma-valerolactone 198.99
    n-decanol 5.06
    triethyl phosphate 13.51
    4-methyl-2-pentanol 5.88
    propionitrile 14.81
    vinylene carbonate 80.1
    1,1,2-trichlorotrifluoroethane 223.72
    DMS 16.9
    cumene 1.79
    2-octanol 4.6
    2-hexanone 9.15
    octyl acetate 6.96
    limonene 5.12
    1,2-dimethoxyethane 108.87
    ethyl orthosilicate 12.09
    tributyl phosphate 9.24
    diacetone alcohol 44.11
    N,N-dimethylaniline 8.84
    acrylonitrile 33.42
    aniline 18.13
    1,3-propanediol 183.69
    bromobenzene 5.46
    dibromomethane 14.28
    1,1,2,2-tetrachloroethane 35.73
    2-methyl-cyclohexyl acetate 13.8
    tetrabutyl urea 12.45
    diisobutyl methanol 5.29
    2-phenylethanol 20.3
    styrene 1.74
    dioctyl adipate 10.55
    dimethyl sulfate 86.28
    ethyl butyrate 13.25
    methyl lactate 61.36
    butyl lactate 17.16
    diethyl carbonate 12.17
    propanediol butyl ether 39.42
    triethyl orthoformate 12.96
    p-tert-butyltoluene 3.37
    methyl 4-tert-butylbenzoate 23.63
    morpholine 106.62
    tert-butylamine 9.6
    n-dodecanol 3.83
    dimethoxymethane 77.47
    ethylene carbonate 61.24
    cyrene 61.71
    2-ethoxyethyl acetate 19.01
    2-ethylhexyl acetate 8.65
    1,2,4-trichlorobenzene 14.89
    4-methylpyridine 22.23
    dibutyl ether 3.97
    2,6-dimethyl-4-heptanol 5.29
    DEF 49.62
    dimethyl isosorbide 64.84
    tetrachloroethylene 29.24
    eugenol 29.36
    triacetin 23.1
    span 80 30.13
    1,4-butanediol 76.35
    1,1-dichloroethane 8.6
    2-methyl-1-pentanol 14.87
    methyl formate 180.77
    2-methyl-1-butanol 19.29
    n-decane 0.44
    butyronitrile 16.4
    3,7-dimethyl-1-octanol 6.9
    1-chlorooctane 2.12
    1-chlorotetradecane 0.99
    n-nonane 0.37
    undecane 0.35
    tert-butylcyclohexane 0.44
    cyclooctane 0.38
    cyclopentanol 37.81
    tetrahydropyran 21.91
    tert-amyl methyl ether 8.96
    2,5,8-trioxanonane 77.43
    1-hexene 0.67
    2-isopropoxyethanol 55.17
    2,2,2-trifluoroethanol 245.64
    methyl butyrate 20.84

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction