2-Amino-2-methyl-1,3-propanediol

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  • Identifiers

    CAS number
    115-69-5

    Molecular formula
    C4H11NO2

    SMILES
    CC(CO)(CO)N

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 51.84%
    Fishy 47.69%
    Sweet 34.5%
    Alcoholic 26.86%
    Ripe 21.87%
    Cheesy 20.38%
    Cooling 19.66%
    Oily 18.06%
    Mint 17.19%
    Savory 16.63%

     

    Flavor
    Odorless 47.62%
    Sweet 32.19%
    Sulfurous 25.69%
    Bitter 25.63%
    Sweet-like 24.11%
    Very slight 21.4%
    Meat broth 19.4%
    Mild 19.26%
    Alcoholic 19.24%
    Cauliflower 19.03%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.8

    pKa est.
    6.41 (neutral)

    Molecular weight
    105.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    255°C

    Flash point

    • 134.98 ˚C est.

  • Synonyms

    • 2-Amino-2-methyl-1,3-propanediol
    • 115-69-5
    • 2-Amino-2-methylpropane-1,3-diol
    • AMPD
    • Aminoglycol
    • Gentimon
    • Aminomethyl propanediol
    • 1,3-Propanediol, 2-amino-2-methyl-
    • Isobutandiol-2-amine
    • 1,1-Di(hydroxymethyl)ethylamine
    • Ammediol
    • 2-Amino-2-methyl-1,3-propandiol
    • CZ7BU4QZJZ
    • NSC-6364
    • CHEBI:991
    • DTXSID7059430
    • RefChem:557559
    • GlyTouCan:G22655ST
    • DTXCID8033356
    • G22655ST
    • 204-100-7
    • Pentaerythritol dichlorohydrin
    • MFCD00004678
    • NSC 6364
    • 2-amino-2-methyl-propane-1,3-diol
    • 2-methyl-2-amino-1,3-propanediol
    • 2-Amino-2-methylpropan-1,3-diol
    • 1,3-Dihydroxy-2-methyl-2-propylamine
    • 1,3-Dihydroxy-2-amino-2-methylpropane
    • 2-Amino-2-methyl-1,3-propanediol(AMPD)
    • Amediol
    • AMPO
    • UNII-CZ7BU4QZJZ
    • EINECS 204-100-7
    • BRN 0635708
    • AI3-03949
    • 1, 2-amino-2-methyl-
    • SCHEMBL23687
    • 4-04-00-01881 (Beilstein Handbook Reference)
    • SCHEMBL750672
    • orb2942433
    • SCHEMBL1663749
    • SCHEMBL5975691
    • SCHEMBL6545694
    • WLN: Q1XZ1 & 1Q
    • UXFQFBNBSPQBJW-UHFFFAOYSA-
    • NSC6364
    • 2-amino-2-methyl-1,3propanediol
    • 2-amino-2-methylpropane-1,3diol
    • 2-amino-2-methyl-1-3-propandiol
    • 2-amino-2-methylpropane 1,3-diol
    • BB_SC-06454
    • 2-hydroxymethyl-2-amino-1-propanol
    • BBL027473
    • SBB004360
    • STL373468
    • AKOS006222995
    • AT27658
    • CS-W017770
    • FA46974
    • HY-W017054
    • MSK168111-100M
    • SB83841
    • 1,3-dihydroxy-2-methyl-2-amino-propane
    • DA-49361
    • SY011284
    • VS-08545
    • propane, 2-amino-1,3-dihydroxy-2-methyl-
    • A0332
    • NS00007933
    • ST50998252
    • 2-Amino-2-methyl-1,3-propanediol, >=99%
    • EN300-93582
    • propane, 2-amino-3-hydroxy-2-hydroxymethyl-
    • 2-AMINO-2-METHYL-1,3-PROPANEDIOL [MI]
    • 2-Amino-2-methylpropane-1,3-diol, high purity
    • F791485
    • Q3598002
    • F2190-0374
    • 95E0210B-CCBA-4485-9DA0-34844FF88E42
    • 2-Amino-2-methyl-1,3-propanediol, BioUltra, >=99.5% (NT)
    • 2-Amino-2-methyl-1,3-propanediol Solution in Methanol, 100ug/mL
    • InChI=1/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3
    • 2-Amino-2-methyl-1,3-propanediol, BioXtra, pH 10.0-12.0 (20 C, 0.5 M in H2O), >=99%
    • 115-69-5

  • Applications

    2-Amino-2-methyl-1,3-propanediol is a diol-amine building block with an amino group and two hydroxyl groups, used as a building block in polymer synthesis. In the polymer and plastics industries it serves as a chain extender and has potential as a crosslinking component for polyurethane and polyurea formulations. It can function as a reactive intermediate for specialty polymers and high-performance materials. In coatings and adhesives, it can act as a crosslinking agent or curing component for epoxy resins and UV-curable systems. It also serves as a synthetic building block for pharmaceutical and agrochemical intermediates. Additionally, it may be employed in electronics-related polymer applications such as encapsulation materials, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 16.35
    methanol 56.04
    isopropanol 4.72
    water 990.61
    ethyl acetate 1.28
    n-propanol 14.85
    acetone 1.43
    n-butanol 8.84
    acetonitrile 2.14
    DMF 13.59
    toluene 0.2
    isobutanol 6.69
    1,4-dioxane 3.09
    methyl acetate 1.45
    THF 6.29
    2-butanone 2.31
    n-pentanol 2.46
    sec-butanol 6.69
    n-hexane 0.22
    ethylene glycol 90.55
    NMP 46.79
    cyclohexane 0.49
    DMSO 21.97
    n-butyl acetate 0.93
    n-octanol 1.23
    chloroform 0.95
    n-propyl acetate 0.72
    acetic acid 100.13
    dichloromethane 0.75
    cyclohexanone 4.52
    propylene glycol 54.3
    isopropyl acetate 0.79
    DMAc 16.36
    2-ethoxyethanol 13.18
    isopentanol 3.62
    n-heptane 0.59
    ethyl formate 3.38
    1,2-dichloroethane 0.51
    n-hexanol 3.13
    2-methoxyethanol 40.35
    isobutyl acetate 0.45
    tetrachloromethane 0.96
    n-pentyl acetate 0.9
    transcutol 13.94
    n-heptanol 2.99
    ethylbenzene 0.14
    MIBK 1.1
    2-propoxyethanol 11.6
    tert-butanol 3.53
    MTBE 0.9
    2-butoxyethanol 9.22
    propionic acid 26.34
    o-xylene 0.4
    formic acid 464.94
    diethyl ether 1.06
    m-xylene 0.3
    p-xylene 0.23
    chlorobenzene 0.25
    dimethyl carbonate 1.27
    n-octane 0.22
    formamide 185.1
    cyclopentanone 7.7
    2-pentanone 1.79
    anisole 0.4
    cyclopentyl methyl ether 3.0
    gamma-butyrolactone 11.18
    1-methoxy-2-propanol 14.3
    pyridine 1.85
    3-pentanone 1.75
    furfural 11.06
    n-dodecane 0.09
    diethylene glycol 25.76
    diisopropyl ether 0.41
    tert-amyl alcohol 5.29
    acetylacetone 1.59
    n-hexadecane 0.09
    acetophenone 0.83
    methyl propionate 2.26
    isopentyl acetate 0.82
    trichloroethylene 1.02
    n-nonanol 1.15
    cyclohexanol 5.94
    benzyl alcohol 1.31
    2-ethylhexanol 1.64
    isooctanol 1.96
    dipropyl ether 1.18
    1,2-dichlorobenzene 0.31
    ethyl lactate 2.73
    propylene carbonate 4.37
    n-methylformamide 28.39
    2-pentanol 3.09
    n-pentane 0.34
    1-propoxy-2-propanol 6.6
    1-methoxy-2-propyl acetate 1.9
    2-(2-methoxypropoxy) propanol 4.92
    mesitylene 0.31
    ε-caprolactone 5.44
    p-cymene 0.43
    epichlorohydrin 3.26
    1,1,1-trichloroethane 0.43
    2-aminoethanol 91.34
    morpholine-4-carbaldehyde 21.84
    sulfolane 26.14
    2,2,4-trimethylpentane 0.26
    2-methyltetrahydrofuran 3.98
    n-hexyl acetate 0.92
    isooctane 0.14
    2-(2-butoxyethoxy)ethanol 7.78
    sec-butyl acetate 0.5
    tert-butyl acetate 1.05
    decalin 0.16
    glycerin 133.04
    diglyme 9.95
    acrylic acid 36.04
    isopropyl myristate 0.38
    n-butyric acid 16.78
    acetyl acetate 1.07
    di(2-ethylhexyl) phthalate 1.01
    ethyl propionate 0.85
    nitromethane 21.1
    1,2-diethoxyethane 0.88
    benzonitrile 0.64
    trioctyl phosphate 0.91
    1-bromopropane 0.37
    gamma-valerolactone 15.16
    n-decanol 0.78
    triethyl phosphate 1.09
    4-methyl-2-pentanol 1.47
    propionitrile 1.82
    vinylene carbonate 3.44
    1,1,2-trichlorotrifluoroethane 20.94
    DMS 0.81
    cumene 0.21
    2-octanol 1.16
    2-hexanone 0.69
    octyl acetate 0.63
    limonene 0.73
    1,2-dimethoxyethane 3.99
    ethyl orthosilicate 1.14
    tributyl phosphate 0.83
    diacetone alcohol 4.73
    N,N-dimethylaniline 0.63
    acrylonitrile 2.65
    aniline 1.54
    1,3-propanediol 54.39
    bromobenzene 0.15
    dibromomethane 0.55
    1,1,2,2-tetrachloroethane 1.04
    2-methyl-cyclohexyl acetate 1.11
    tetrabutyl urea 1.24
    diisobutyl methanol 0.97
    2-phenylethanol 1.4
    styrene 0.13
    dioctyl adipate 0.71
    dimethyl sulfate 3.61
    ethyl butyrate 1.18
    methyl lactate 8.39
    butyl lactate 2.98
    diethyl carbonate 0.64
    propanediol butyl ether 9.35
    triethyl orthoformate 1.28
    p-tert-butyltoluene 0.45
    methyl 4-tert-butylbenzoate 2.48
    morpholine 7.91
    tert-butylamine 1.71
    n-dodecanol 0.56
    dimethoxymethane 3.57
    ethylene carbonate 2.52
    cyrene 10.67
    2-ethoxyethyl acetate 1.33
    2-ethylhexyl acetate 0.68
    1,2,4-trichlorobenzene 0.47
    4-methylpyridine 1.03
    dibutyl ether 0.47
    2,6-dimethyl-4-heptanol 0.97
    DEF 4.62
    dimethyl isosorbide 6.65
    tetrachloroethylene 1.81
    eugenol 3.64
    triacetin 1.86
    span 80 6.5
    1,4-butanediol 15.18
    1,1-dichloroethane 0.33
    2-methyl-1-pentanol 1.71
    methyl formate 10.57
    2-methyl-1-butanol 5.97
    n-decane 0.17
    butyronitrile 1.6
    3,7-dimethyl-1-octanol 0.93
    1-chlorooctane 0.28
    1-chlorotetradecane 0.12
    n-nonane 0.17
    undecane 0.12
    tert-butylcyclohexane 0.15
    cyclooctane 0.29
    cyclopentanol 11.92
    tetrahydropyran 2.31
    tert-amyl methyl ether 1.34
    2,5,8-trioxanonane 7.84
    1-hexene 0.3
    2-isopropoxyethanol 4.77
    2,2,2-trifluoroethanol 60.26
    methyl butyrate 1.28

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction