2-Amino-1-butanol

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  • Identifiers

    CAS number
    96-20-8

    Molecular formula
    C4H11NO

    SMILES
    CCC(CO)N

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Fishy 70.87%
    Cheesy 46.36%
    Odorless 40.08%
    Ripe 38.9%
    Alcoholic 26.97%
    Oily 24.94%
    Sweet 20.72%
    Fermented 18.78%
    Malty 18.0%
    Animal 17.81%

     

    Flavor
    Sulfurous 39.45%
    Odorless 36.03%
    Fishy 33.57%
    Onion 28.6%
    Meaty 25.92%
    Mild 24.36%
    Ammoniacal 22.8%
    Roasted 22.15%
    Sulfury 22.12%
    Sweet 21.19%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    -0.4

    pKa est.
    6.21 (neutral)

    Molecular weight
    89.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    179°C

    Flash point

    • 74.0 ˚C est.

  • Synonyms

    • 2-Aminobutan-1-ol
    • 2-Amino-1-butanol
    • 96-20-8
    • 2-Aminobutanol
    • 1-BUTANOL, 2-AMINO-
    • 2-Aminobutyl alcohol
    • Butanol-2-amine
    • 1-(Hydroxymethyl)propylamine
    • 2-Amino-1-hydroxybutane
    • N008Q02GPS
    • NSC-1068
    • DTXSID60859935
    • RefChem:85045
    • DTXCID50209465
    • 202-488-2
    • 235-940-2
    • DL-2-Amino-1-butanol
    • 13054-87-0
    • 1-Hydroxy-2-butylamine
    • aminobutanol
    • MFCD00008095
    • 1-Hydroxybutan-2-amine
    • (+/-)-2-Amino-1-butanol
    • 2-Amino-butan-1-ol
    • ( inverted exclamation markA)-2-Amino-1-butanol
    • r-(-)-2-amino-1-butanol
    • 1-Butanol, 2-amino-, (S)-
    • butane, 2-amino-1-hydroxy-
    • L-2-AMINO-1-BUTANOL
    • 2-Amino-n-butyl alcohol
    • H-Ala-Oet HCl
    • (-)-2-Aminobutanol
    • DL-2-Aminobutanol
    • 2-Amino-1-butanol #
    • R(-)-2-Amino-1-butanol
    • NSC 1068
    • s-(+)-2-amino-1-butanol
    • 1-Hydroxy-2-aminobutane
    • 1-Hydroxy-sec-butylamine
    • EINECS 202-488-2
    • EINECS 235-940-2
    • Ethambutol EP Impurity A
    • (rs)-2-amino-1-butanol
    • BRN 1098274
    • UNII-N008Q02GPS
    • AI3-03357
    • 2-Amino-n-butanol
    • dl-2-amino-1butanol
    • rac-2-amino-1-butanol
    • EC 202-488-2
    • (?)-2-Amino-1-butanol
    • Oprea1_102773
    • SCHEMBL44084
    • 2-Amino-1-butanol, 97%
    • 4-04-00-01705 (Beilstein Handbook Reference)
    • r-(-)-2 amino-1-butanol
    • AMINOBUTANOL [USP-RS]
    • SCHEMBL360463
    • WLN: ZY2&1Q
    • (+/-) 2-amino-1-butanol
    • .+/-.-2-Amino-1-butanol
    • CHEMBL327032
    • SCHEMBL1509703
    • SCHEMBL1577039
    • SCHEMBL2252927
    • SCHEMBL6014458
    • DL-.ALPHA.-AMINOBUTANOL
    • SCHEMBL11096993
    • NSC1068
    • 2-AMINO-1-BUTANOL [MI]
    • BB_SC-06587
    • STR02718
    • 1-(r,s)-(hydroxymethyl)propylamine
    • BBL027677
    • EBC-14658
    • STL264181
    • AKOS000119782
    • AKOS016050696
    • Ethambutol Hydrochloride EP Impurity A
    • SB44650
    • SB44694
    • SB83767
    • [(1R)-1-(hydroxymethyl)propyl]ammonium
    • 1-Butanol, 2-amino-, (.+/-.)-
    • 2-AMINO-1-BUTANOL, (+/-)-
    • SY015133
    • SY049464
    • DB-016690
    • DB-016762
    • DB-031995
    • A0684
    • A8286
    • A8287
    • NS00001268
    • EN300-19709
    • D87517
    • F091481
    • Q27284318
    • ETHAMBUTOL HYDROCHLORIDE IMPURITY A [EP IMPURITY]
    • F2190-0370
    • Z104474862
    • Aminobutanol, United States Pharmacopeia (USP) Reference Standard
    • Aminobutanol, Pharmaceutical Secondary Standard; Certified Reference Material
    • 96-20-8

  • Applications

    2-Amino-1-butanol (CAS 96-20-8) is a versatile amino alcohol that serves as a synthetic intermediate across several industrial sectors: it is commonly used as a building block in the synthesis of pharmaceutical agents bearing β-amino alcohol motifs; it functions as an intermediate for agrochemical active ingredients; it can act as a reactive amine component in epoxy resin curing formulations and related coatings and adhesives; it serves as a precursor to polyetheramines and other polymeric curing agents used in plastics and coatings; and it is employed in the synthesis of amine-containing surfactants and specialty cleaners. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 32.58
    methanol 137.16
    isopropanol 7.57
    water 362.64
    ethyl acetate 3.78
    n-propanol 19.0
    acetone 3.13
    n-butanol 15.04
    acetonitrile 5.19
    DMF 8.21
    toluene 0.59
    isobutanol 13.01
    1,4-dioxane 7.63
    methyl acetate 4.09
    THF 19.02
    2-butanone 3.76
    n-pentanol 7.44
    sec-butanol 8.34
    n-hexane 0.39
    ethylene glycol 107.91
    NMP 67.67
    cyclohexane 0.72
    DMSO 53.58
    n-butyl acetate 10.61
    n-octanol 3.97
    chloroform 4.79
    n-propyl acetate 3.33
    acetic acid 296.16
    dichloromethane 3.95
    cyclohexanone 15.51
    propylene glycol 56.54
    isopropyl acetate 2.3
    DMAc 14.15
    2-ethoxyethanol 27.74
    isopentanol 10.63
    n-heptane 1.1
    ethyl formate 11.62
    1,2-dichloroethane 2.1
    n-hexanol 17.23
    2-methoxyethanol 56.16
    isobutyl acetate 2.33
    tetrachloromethane 3.55
    n-pentyl acetate 5.11
    transcutol 59.06
    n-heptanol 10.03
    ethylbenzene 0.38
    MIBK 2.34
    2-propoxyethanol 41.0
    tert-butanol 9.35
    MTBE 1.87
    2-butoxyethanol 26.18
    propionic acid 66.46
    o-xylene 0.98
    formic acid 682.06
    diethyl ether 1.55
    m-xylene 0.82
    p-xylene 0.75
    chlorobenzene 2.0
    dimethyl carbonate 1.6
    n-octane 0.36
    formamide 246.73
    cyclopentanone 22.74
    2-pentanone 2.9
    anisole 1.35
    cyclopentyl methyl ether 7.17
    gamma-butyrolactone 44.27
    1-methoxy-2-propanol 19.35
    pyridine 7.03
    3-pentanone 2.33
    furfural 54.12
    n-dodecane 0.21
    diethylene glycol 73.1
    diisopropyl ether 0.76
    tert-amyl alcohol 11.6
    acetylacetone 4.61
    n-hexadecane 0.21
    acetophenone 2.98
    methyl propionate 3.71
    isopentyl acetate 8.62
    trichloroethylene 5.85
    n-nonanol 3.57
    cyclohexanol 14.88
    benzyl alcohol 5.07
    2-ethylhexanol 9.65
    isooctanol 7.58
    dipropyl ether 3.43
    1,2-dichlorobenzene 2.55
    ethyl lactate 7.28
    propylene carbonate 21.53
    n-methylformamide 30.92
    2-pentanol 4.69
    n-pentane 0.42
    1-propoxy-2-propanol 26.04
    1-methoxy-2-propyl acetate 9.33
    2-(2-methoxypropoxy) propanol 16.18
    mesitylene 0.85
    ε-caprolactone 22.17
    p-cymene 1.78
    epichlorohydrin 13.74
    1,1,1-trichloroethane 2.02
    2-aminoethanol 107.09
    morpholine-4-carbaldehyde 39.07
    sulfolane 82.35
    2,2,4-trimethylpentane 0.51
    2-methyltetrahydrofuran 12.91
    n-hexyl acetate 4.89
    isooctane 0.35
    2-(2-butoxyethoxy)ethanol 25.35
    sec-butyl acetate 1.91
    tert-butyl acetate 3.4
    decalin 0.42
    glycerin 141.36
    diglyme 32.37
    acrylic acid 82.26
    isopropyl myristate 1.78
    n-butyric acid 61.97
    acetyl acetate 4.79
    di(2-ethylhexyl) phthalate 5.98
    ethyl propionate 2.13
    nitromethane 63.58
    1,2-diethoxyethane 4.95
    benzonitrile 4.66
    trioctyl phosphate 4.7
    1-bromopropane 0.95
    gamma-valerolactone 44.02
    n-decanol 2.57
    triethyl phosphate 4.85
    4-methyl-2-pentanol 3.54
    propionitrile 3.83
    vinylene carbonate 17.85
    1,1,2-trichlorotrifluoroethane 60.46
    DMS 3.77
    cumene 0.65
    2-octanol 3.68
    2-hexanone 2.51
    octyl acetate 2.94
    limonene 2.86
    1,2-dimethoxyethane 10.49
    ethyl orthosilicate 4.89
    tributyl phosphate 5.4
    diacetone alcohol 11.7
    N,N-dimethylaniline 1.54
    acrylonitrile 6.75
    aniline 5.6
    1,3-propanediol 90.4
    bromobenzene 1.18
    dibromomethane 2.44
    1,1,2,2-tetrachloroethane 5.03
    2-methyl-cyclohexyl acetate 7.53
    tetrabutyl urea 5.75
    diisobutyl methanol 4.1
    2-phenylethanol 8.63
    styrene 0.47
    dioctyl adipate 4.03
    dimethyl sulfate 5.8
    ethyl butyrate 6.59
    methyl lactate 11.09
    butyl lactate 11.61
    diethyl carbonate 3.69
    propanediol butyl ether 24.08
    triethyl orthoformate 5.96
    p-tert-butyltoluene 1.72
    methyl 4-tert-butylbenzoate 8.83
    morpholine 13.51
    tert-butylamine 4.04
    n-dodecanol 1.9
    dimethoxymethane 3.22
    ethylene carbonate 12.63
    cyrene 24.51
    2-ethoxyethyl acetate 7.19
    2-ethylhexyl acetate 6.52
    1,2,4-trichlorobenzene 3.64
    4-methylpyridine 3.9
    dibutyl ether 1.7
    2,6-dimethyl-4-heptanol 4.1
    DEF 5.75
    dimethyl isosorbide 29.75
    tetrachloroethylene 9.07
    eugenol 12.6
    triacetin 7.94
    span 80 22.3
    1,4-butanediol 33.96
    1,1-dichloroethane 1.12
    2-methyl-1-pentanol 7.07
    methyl formate 17.65
    2-methyl-1-butanol 12.99
    n-decane 0.31
    butyronitrile 4.48
    3,7-dimethyl-1-octanol 4.11
    1-chlorooctane 0.85
    1-chlorotetradecane 0.42
    n-nonane 0.3
    undecane 0.25
    tert-butylcyclohexane 0.45
    cyclooctane 0.39
    cyclopentanol 26.75
    tetrahydropyran 4.71
    tert-amyl methyl ether 2.26
    2,5,8-trioxanonane 27.68
    1-hexene 0.68
    2-isopropoxyethanol 12.87
    2,2,2-trifluoroethanol 116.14
    methyl butyrate 4.21

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction